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Jianxu Li
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Plant Metabolism
Structural Biology
Metabolic Enzymes
Enzyme Engineering
Biochemistry
Molecular Biology
Plant Physiology
Genetic Engineering
Protein Structure
Biosynthesis
Areas of Focus
- Plant Metabolism and Structural Biology
- Engineering of Metabolic Enzymes
Work Experience
- 2023-04~Present - Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences - Associate Researcher, Young Research Group Leader
- 2020-05~2023-03 - Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences - Associate Researcher
- 2017-12~2020-04 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Associate Researcher
- 2015-11~2017-11 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Assistant Researcher
- 2013-06~2015-10 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Postdoctoral Researcher
- 2012-06~2013-05 - University of California, Berkeley - Postdoctoral Researcher
- 2005-09~2012-07 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Ph.D. Student
- 2001-09~2005-07 - Shandong Normal University - Bachelor's Student
Academic Background & Achievements
- 2005-09--2012-07 Ph.D.: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences
- 2001-09--2005-07 Bachelor's: Shandong Normal University
Publications
- A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, 5th Author, 2022
- Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4 '-deoxyflavones in Scutellaria baicalensis Georgi, 3rd Author, 2022
- Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum, 11th Author, 2022
- Functional and Structural Investigation of Chalcone Synthases Based on Integrated Metabolomics and Transcriptome Analysis on Flavonoids and Anthocyanins Biosynthesis of the Fern Cyclosorus parasiticus, 11th Author, 2021
- Structural insights into phospholipase D function, 2nd Author, 2021
- A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes, 5th Author, 2021
- 1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue, 3rd Author, 2021
- Structural and Biochemical Insights Into Two BAHD Acyltransferases (AtSHT and AtSDT) Involved in Phenolamide Biosynthesis, 2nd Author, 2021
- Occurrence and biosynthesis of plant sesterterpenes (C25), a new addition to terpene diversity, 2nd Author, 2021
- Aromatization of natural products by a specialized detoxification enzyme, 7th Author, 2020
- Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D, 1st Author, 2020
- Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases, 2nd Author, 2020
- Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1, 2nd Author, 2020
- Diterpenoid UDP-Glycosyltransferases from Chinese Sweet Tea and Ashitaba Complete the Biosynthesis of Rubusoside, 3rd Author, 2018
- Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, 2nd Author, 2017
- Molecular mechanism of environmental d -xylose perception by a XylFII-LytS complex in bacteria, 1st Author, 2017
- Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua, 2nd Author, 2016
- Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants., 4th Author, 2016
- Isolation and characterization of AaAER, a novel double bond reductase from Artemisia annua, 2nd Author, 2015
- Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex, 6th Author, 2015
- ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes, 9th Author, 2015
- Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency, 1st Author, 2013
- Biosynthesis and Regulation of Secondary Terpenoid Metabolism in Plants, 4th Author, 2013
- The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua L., 2nd Author, 2012
- Increased Accumulation of Artemisinin and Anthocyanins in Artemisia annua Expressing the Arabidopsis Blue Light Receptor CRY1, 3rd Author, 2009
- The rice ( E)-β-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes, 3rd Author, 2007
Awards
- Shanghai Oriental Talent Youth Project (2023): Provincial Level
- Sanofi-Excellent Young Talent Award, Shanghai Institute of Life Sciences, Chinese Academy of Sciences (2018): Institute Level
