Professor | Jianxu Li | Asia Growth Partners

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Name	Jianxu Li
Contact Information	lijx@cemps.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Jianxu Li

Contact Information

lijx@cemps.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2005-09--2012-07 Ph.D.: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences 2001-09--2005-07 Bachelor's: Shandong Normal University
Work Experience	2023-04~Present - Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences - Associate Researcher, Young Research Group Leader 2020-05~2023-03 - Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences - Associate Researcher 2017-12~2020-04 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Associate Researcher 2015-11~2017-11 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Assistant Researcher 2013-06~2015-10 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Postdoctoral Researcher 2012-06~2013-05 - University of California, Berkeley - Postdoctoral Researcher 2005-09~2012-07 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Ph.D. Student 2001-09~2005-07 - Shandong Normal University - Bachelor's Student
Awards	Shanghai Oriental Talent Youth Project (2023): Provincial Level Sanofi-Excellent Young Talent Award, Shanghai Institute of Life Sciences, Chinese Academy of Sciences (2018): Institute Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2005-09--2012-07 Ph.D.: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences
2001-09--2005-07 Bachelor's: Shandong Normal University

Work Experience

2023-04~Present - Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences - Associate Researcher, Young Research Group Leader
2020-05~2023-03 - Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences - Associate Researcher
2017-12~2020-04 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Associate Researcher
2015-11~2017-11 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Assistant Researcher
2013-06~2015-10 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Postdoctoral Researcher
2012-06~2013-05 - University of California, Berkeley - Postdoctoral Researcher
2005-09~2012-07 - Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences - Ph.D. Student
2001-09~2005-07 - Shandong Normal University - Bachelor's Student

Awards

Shanghai Oriental Talent Youth Project (2023): Provincial Level
Sanofi-Excellent Young Talent Award, Shanghai Institute of Life Sciences, Chinese Academy of Sciences (2018): Institute Level

Areas of Focus	Plant Metabolism and Structural Biology Engineering of Metabolic Enzymes
Publications	A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, 5th Author, 2022 Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4 '-deoxyflavones in Scutellaria baicalensis Georgi, 3rd Author, 2022 Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum, 11th Author, 2022 Functional and Structural Investigation of Chalcone Synthases Based on Integrated Metabolomics and Transcriptome Analysis on Flavonoids and Anthocyanins Biosynthesis of the Fern Cyclosorus parasiticus, 11th Author, 2021 Structural insights into phospholipase D function, 2nd Author, 2021 A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes, 5th Author, 2021 1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue, 3rd Author, 2021 Structural and Biochemical Insights Into Two BAHD Acyltransferases (AtSHT and AtSDT) Involved in Phenolamide Biosynthesis, 2nd Author, 2021 Occurrence and biosynthesis of plant sesterterpenes (C25), a new addition to terpene diversity, 2nd Author, 2021 Aromatization of natural products by a specialized detoxification enzyme, 7th Author, 2020 Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D, 1st Author, 2020 Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases, 2nd Author, 2020 Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1, 2nd Author, 2020 Diterpenoid UDP-Glycosyltransferases from Chinese Sweet Tea and Ashitaba Complete the Biosynthesis of Rubusoside, 3rd Author, 2018 Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, 2nd Author, 2017 Molecular mechanism of environmental d -xylose perception by a XylFII-LytS complex in bacteria, 1st Author, 2017 Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua, 2nd Author, 2016 Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants., 4th Author, 2016 Isolation and characterization of AaAER, a novel double bond reductase from Artemisia annua, 2nd Author, 2015 Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex, 6th Author, 2015 ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes, 9th Author, 2015 Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency, 1st Author, 2013 Biosynthesis and Regulation of Secondary Terpenoid Metabolism in Plants, 4th Author, 2013 The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua L., 2nd Author, 2012 Increased Accumulation of Artemisinin and Anthocyanins in Artemisia annua Expressing the Arabidopsis Blue Light Receptor CRY1, 3rd Author, 2009 The rice ( E)-β-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes, 3rd Author, 2007

Areas of Focus

Plant Metabolism and Structural Biology
Engineering of Metabolic Enzymes

Publications

A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, 5th Author, 2022
Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4 '-deoxyflavones in Scutellaria baicalensis Georgi, 3rd Author, 2022
Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum, 11th Author, 2022
Functional and Structural Investigation of Chalcone Synthases Based on Integrated Metabolomics and Transcriptome Analysis on Flavonoids and Anthocyanins Biosynthesis of the Fern Cyclosorus parasiticus, 11th Author, 2021
Structural insights into phospholipase D function, 2nd Author, 2021
A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes, 5th Author, 2021
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue, 3rd Author, 2021
Structural and Biochemical Insights Into Two BAHD Acyltransferases (AtSHT and AtSDT) Involved in Phenolamide Biosynthesis, 2nd Author, 2021
Occurrence and biosynthesis of plant sesterterpenes (C25), a new addition to terpene diversity, 2nd Author, 2021
Aromatization of natural products by a specialized detoxification enzyme, 7th Author, 2020
Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D, 1st Author, 2020
Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases, 2nd Author, 2020
Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1, 2nd Author, 2020
Diterpenoid UDP-Glycosyltransferases from Chinese Sweet Tea and Ashitaba Complete the Biosynthesis of Rubusoside, 3rd Author, 2018
Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, 2nd Author, 2017
Molecular mechanism of environmental d -xylose perception by a XylFII-LytS complex in bacteria, 1st Author, 2017
Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua, 2nd Author, 2016
Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants., 4th Author, 2016
Isolation and characterization of AaAER, a novel double bond reductase from Artemisia annua, 2nd Author, 2015
Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex, 6th Author, 2015
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes, 9th Author, 2015
Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency, 1st Author, 2013
Biosynthesis and Regulation of Secondary Terpenoid Metabolism in Plants, 4th Author, 2013
The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua L., 2nd Author, 2012
Increased Accumulation of Artemisinin and Anthocyanins in Artemisia annua Expressing the Arabidopsis Blue Light Receptor CRY1, 3rd Author, 2009
The rice ( E)-β-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes, 3rd Author, 2007

Plant Metabolism Structural Biology Metabolic Enzymes Enzyme Engineering Biochemistry Molecular Biology Plant Physiology Genetic Engineering Protein Structure Biosynthesis

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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