Areas of Focus
- Tumor Molecular Biology
Work Experience
- 2023-01~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Researcher
- 2019-05~2022-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
- 2013-01~2019-04 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
- 2010-01~2012-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Postdoctoral Researcher
- 2009-05~2009-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2003-09--2009-04 PhD: Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences
- 1999-09--2003-07 Bachelor's: East China Normal University
Publications
- XAF1 promotes colorectal cancer metastasis via VCP-RNF114-JUP axis, JOURNAL OF CELL BIOLOGY, 2024
- PPDPF Promotes the Development of Mutant KRAS-Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1, ADVANCED SCIENCE, 2023
- ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2, CELL DEATH AND DIFFERENTIATION, 2023
- PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1, CELL REPORTS, 2023
- Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma, CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2022
- PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT3, ONCOGENE, 2022
- INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling, EXPERIMENTAL CELL RESEARCH, 2021
- PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling, NATURE COMMUNICATIONS, 2021
- Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis, ONCOGENE, 2021
- Ochratoxin A Induces Steatosis via PPAR-CD36 Axis, TOXINS (Basel), 2021
- Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway, CANCER SCIENCE, 2020
- Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020
- Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of beta-catenin/TCF/LEF signalling, CELL PROLIFERATION, 2019
- CHML promotes liver cancer metastasis by facilitating Rab14 recycle, NATURE COMMUNICATIONS, 2019
- BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis, ONCOGENE, 2019
- FABP4 suppresses proliferation and invasion of hepatocellular carcinoma cells and predicts a poor prognosis for hepatocellular carcinoma, CANCER MEDICINE, 2018
- Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis, BRITISH JOURNAL OF CANCER, 2018
- hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating beta-Catenin Signaling, CANCER RESEARCH, 2018
- PRMT1 Promoted HCC Growth and Metastasis In Vitro and In Vivo via Activating the STAT3 Signalling Pathway, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018
- EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer, JOURNAL OF BIOLOGICAL CHEMISTRY, 2017
- Iron overload in hereditary tyrosinemia type 1 induces liver injury through the Sp1/Tfr2/hepcidin axis, JOURNAL OF HEPATOLOGY, 2016
- Sorafenib Enriches Epithelial Cell Adhesion Molecule-Positive Tumor Initiating Cells and Exacerbates a Subtype of Hepatocellular Carcinoma Through TSC2-AKT Cascade, HEPATOLOGY, 2015
- RACK1, a versatile hub in cancer, ONCOGENE, 2015
- RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex, CELL RESEARCH, 2014
- Recruitment of Phosphatase PP2A by RACK1 Adaptor Protein Deactivates Transcription Factor IRF3 and Limits Type I Interferon Signaling, IMMUNITY, 2014
- All-trans retinoic acid potentiates the chemotherapeutic effect of cisplatin by inducing differentiation of tumor initiating cells in liver cancer, JOURNAL OF HEPATOLOGY, 2013
- The roles and therapeutic potentials of Ephs and ephrins in lung cancer, EXPERIMENTAL CELL RESEARCH, 2013
- Proteomics in gastric cancer research: Benefits and challenges, PROTEOMICS CLINICAL APPLICATIONS, 2009
- Ephrina5 acts as a tumor suppressor in glioma by negative regulation of epidermal growth factor receptor, ONCOGENE, 2009
- Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid, MOLECULAR NUTRITION & FOOD RESEARCH, 2008
- Cleavage of focal adhesion kinase (FAK) is essential in adipocyte differentiation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007
Awards
- Sanofi-Excellent Young Talent Award, Chinese Academy of Sciences, 2018