2003-09--2009-04 PhD: Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences
1999-09--2003-07 Bachelor's: East China Normal University
2023-01~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Researcher
2019-05~2022-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
2013-01~2019-04 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
2010-01~2012-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Postdoctoral Researcher
2009-05~2009-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Assistant Researcher
Sanofi-Excellent Young Talent Award, Chinese Academy of Sciences, 2018
Research
Tumor Molecular Biology
XAF1 promotes colorectal cancer metastasis via VCP-RNF114-JUP axis, JOURNAL OF CELL BIOLOGY, 2024
PPDPF Promotes the Development of Mutant KRAS-Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1, ADVANCED SCIENCE, 2023
ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2, CELL DEATH AND DIFFERENTIATION, 2023
PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1, CELL REPORTS, 2023
Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma, CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2022
PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT3, ONCOGENE, 2022
INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling, EXPERIMENTAL CELL RESEARCH, 2021
PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling, NATURE COMMUNICATIONS, 2021
Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis, ONCOGENE, 2021
Ochratoxin A Induces Steatosis via PPAR-CD36 Axis, TOXINS (Basel), 2021
Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway, CANCER SCIENCE, 2020
Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020
Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of beta-catenin/TCF/LEF signalling, CELL PROLIFERATION, 2019
CHML promotes liver cancer metastasis by facilitating Rab14 recycle, NATURE COMMUNICATIONS, 2019
BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis, ONCOGENE, 2019
FABP4 suppresses proliferation and invasion of hepatocellular carcinoma cells and predicts a poor prognosis for hepatocellular carcinoma, CANCER MEDICINE, 2018
Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis, BRITISH JOURNAL OF CANCER, 2018
hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating beta-Catenin Signaling, CANCER RESEARCH, 2018
PRMT1 Promoted HCC Growth and Metastasis In Vitro and In Vivo via Activating the STAT3 Signalling Pathway, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018
EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer, JOURNAL OF BIOLOGICAL CHEMISTRY, 2017
Iron overload in hereditary tyrosinemia type 1 induces liver injury through the Sp1/Tfr2/hepcidin axis, JOURNAL OF HEPATOLOGY, 2016
Sorafenib Enriches Epithelial Cell Adhesion Molecule-Positive Tumor Initiating Cells and Exacerbates a Subtype of Hepatocellular Carcinoma Through TSC2-AKT Cascade, HEPATOLOGY, 2015
RACK1, a versatile hub in cancer, ONCOGENE, 2015
RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex, CELL RESEARCH, 2014
Recruitment of Phosphatase PP2A by RACK1 Adaptor Protein Deactivates Transcription Factor IRF3 and Limits Type I Interferon Signaling, IMMUNITY, 2014
All-trans retinoic acid potentiates the chemotherapeutic effect of cisplatin by inducing differentiation of tumor initiating cells in liver cancer, JOURNAL OF HEPATOLOGY, 2013
The roles and therapeutic potentials of Ephs and ephrins in lung cancer, EXPERIMENTAL CELL RESEARCH, 2013
Proteomics in gastric cancer research: Benefits and challenges, PROTEOMICS CLINICAL APPLICATIONS, 2009
Ephrina5 acts as a tumor suppressor in glioma by negative regulation of epidermal growth factor receptor, ONCOGENE, 2009
Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid, MOLECULAR NUTRITION & FOOD RESEARCH, 2008
Cleavage of focal adhesion kinase (FAK) is essential in adipocyte differentiation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007
