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Jingjing Li
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
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Cancer Molecular Biology Tumor Oncology Cell Biology Genetics Biochemistry Pathology Research Medicine
Areas of Focus
  • Tumor Molecular Biology
Work Experience
  • 2023-01~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Researcher
  • 2019-05~2022-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
  • 2013-01~2019-04 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
  • 2010-01~2012-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Postdoctoral Researcher
  • 2009-05~2009-12 - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
  • 2003-09--2009-04 PhD: Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences
  • 1999-09--2003-07 Bachelor's: East China Normal University
Publications
  • XAF1 promotes colorectal cancer metastasis via VCP-RNF114-JUP axis, JOURNAL OF CELL BIOLOGY, 2024
  • PPDPF Promotes the Development of Mutant KRAS-Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1, ADVANCED SCIENCE, 2023
  • ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2, CELL DEATH AND DIFFERENTIATION, 2023
  • PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1, CELL REPORTS, 2023
  • Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma, CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2022
  • PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT3, ONCOGENE, 2022
  • INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling, EXPERIMENTAL CELL RESEARCH, 2021
  • PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling, NATURE COMMUNICATIONS, 2021
  • Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis, ONCOGENE, 2021
  • Ochratoxin A Induces Steatosis via PPAR-CD36 Axis, TOXINS (Basel), 2021
  • Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway, CANCER SCIENCE, 2020
  • Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020
  • Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of beta-catenin/TCF/LEF signalling, CELL PROLIFERATION, 2019
  • CHML promotes liver cancer metastasis by facilitating Rab14 recycle, NATURE COMMUNICATIONS, 2019
  • BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis, ONCOGENE, 2019
  • FABP4 suppresses proliferation and invasion of hepatocellular carcinoma cells and predicts a poor prognosis for hepatocellular carcinoma, CANCER MEDICINE, 2018
  • Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis, BRITISH JOURNAL OF CANCER, 2018
  • hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating beta-Catenin Signaling, CANCER RESEARCH, 2018
  • PRMT1 Promoted HCC Growth and Metastasis In Vitro and In Vivo via Activating the STAT3 Signalling Pathway, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018
  • EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer, JOURNAL OF BIOLOGICAL CHEMISTRY, 2017
  • Iron overload in hereditary tyrosinemia type 1 induces liver injury through the Sp1/Tfr2/hepcidin axis, JOURNAL OF HEPATOLOGY, 2016
  • Sorafenib Enriches Epithelial Cell Adhesion Molecule-Positive Tumor Initiating Cells and Exacerbates a Subtype of Hepatocellular Carcinoma Through TSC2-AKT Cascade, HEPATOLOGY, 2015
  • RACK1, a versatile hub in cancer, ONCOGENE, 2015
  • RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex, CELL RESEARCH, 2014
  • Recruitment of Phosphatase PP2A by RACK1 Adaptor Protein Deactivates Transcription Factor IRF3 and Limits Type I Interferon Signaling, IMMUNITY, 2014
  • All-trans retinoic acid potentiates the chemotherapeutic effect of cisplatin by inducing differentiation of tumor initiating cells in liver cancer, JOURNAL OF HEPATOLOGY, 2013
  • The roles and therapeutic potentials of Ephs and ephrins in lung cancer, EXPERIMENTAL CELL RESEARCH, 2013
  • Proteomics in gastric cancer research: Benefits and challenges, PROTEOMICS CLINICAL APPLICATIONS, 2009
  • Ephrina5 acts as a tumor suppressor in glioma by negative regulation of epidermal growth factor receptor, ONCOGENE, 2009
  • Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid, MOLECULAR NUTRITION & FOOD RESEARCH, 2008
  • Cleavage of focal adhesion kinase (FAK) is essential in adipocyte differentiation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007
Awards
  • Sanofi-Excellent Young Talent Award, Chinese Academy of Sciences, 2018
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