2011-09 to 2018-06 Master's and Ph.D. in Biochemical Engineering: Tianjin University
2007-09 to 2011-06 Bachelor's in Bioengineering: Tianjin University
2022-07 to Present - Chinese Academy of Sciences Tianjin Institute of Industrial Biotechnology - Associate Researcher
2018-07 to 2022-07 - Chinese Academy of Sciences Tianjin Institute of Industrial Biotechnology - Postdoctoral Researcher
2011-09 to 2018-06 - Tianjin University - Master's and Ph.D. in Biochemical Engineering
2007-09 to 2011-06 - Tianjin University - Bachelor's in Bioengineering
Chinese Academy of Sciences Fourth 'Koyuan Craftsman' (Team) (2023)
Research
Automated Design and Construction of Engineering Strains Metabolic Engineering and Systems Biology Multi-gene Simultaneous Editing Technology
Automated characterization and analysis of expression compatibility between regulatory sequences and metabolic genes in Escherichia coli, Synthetic and Systems Biotechnology, 2024
Construction of L-phenylalanine High-producing Corynebacterium glutamicum Engineered Strains via Multi-gene Simultaneous Regulation Combined with High-throughput Screening, 生物技术通报, 2023
ecBSU1: A Genome-Scale Enzyme-Constrained Model of Bacillus subtilis Based on the ECMpy Workflow, MICROORGANISMS, 2023
Reconstruction of a Genome-Scale Metabolic Network for Shewanella oneidensis MR-1 and Analysis of its Metabolic Potential for Bioelectrochemical Systems, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022
Construction and Analysis of an Enzyme-Constrained Metabolic Model of Corynebacterium glutamicum, BIOMOLECULES, 2022
Global Cellular Metabolic Rewiring Adapts Corynebacterium glutamicum to Efficient Nonnatural Xylose Utilization, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2022
Advances in automated high-throughput editing and screening of engineered strains, 生物工程学报, 2022
Enhanced 3-Hydroxypropionic Acid Production From Acetate via the Malonyl-CoA Pathway in Corynebacterium glutamicum, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022
Recent progress in ergothioneine biosynthesis: a review, 生物工程学报, 2022
Natural 5-Aminolevulinic Acid: Sources, Biosynthesis, Detection and Applications, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022
面向微生物遗传操作的编辑序列设计工具的研究进展, 合成生物学, 2022
AutoESD: a web tool for automatic editing sequence design for genetic manipulation of microorganisms, NUCLEIC ACIDS RESEARCH, 2022
Advances in biotechnological production of beta-alanine, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2021
GEDpm-cg: Genome Editing Automated Design Platform for Point Mutation Construction in Corynebacterium glutamicum, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021
Non-natural Aldol Reactions Enable the Design and Construction of Novel One-Carbon Assimilation Pathways in vitro, FRONTIERS IN MICROBIOLOGY, 2021
Engineering central pathways for industrial-level (3 R )-acetoin biosynthesis in Corynebacterium glutamicum, MICROBIAL CELL FACTORIES, 2020
Substrate profiling and tolerance testing of Halomonas TD01 suggest its potential application in sustainable manufacturing of chemicals, JOURNAL OF BIOTECHNOLOGY, 2020
One-pot efficient biosynthesis of (3R)-acetoin from pyruvate by a two-enzyme cascade, CATALYSIS SCIENCE & TECHNOLOGY, 2020
Efficient solid-state fermentation for the production of 5-aminolevulinic acid enriched feed using recombinant Saccharomyces cerevisiae, JOURNAL OF BIOTECHNOLOGY, 2020
Engineering Corynebacterium glutamicum for the Efficient Production of 3-Hydroxypropionic Acid from a Mixture of Glucose and Acetate via the Malonyl-CoA Pathway, CATALYSTS, 2020
In vitro biosynthesis of optically pure d-(-)-acetoin from meso-2,3-butanediol using 2,3-butanediol dehydrogenase and NADH oxidase, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2019
Screening, expression, purification and characterization of CoA-transferases for lactoyl-CoA generation, JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2019
Systematic design and in vitro validation of novel one-carbon assimilation pathways, METABOLIC ENGINEERING, 2019
Metabolic engineering of Corynebacterium glutamicum for efficient production of succinate from lignocellulosic hydrolysate, BIOTECHNOLOGY FOR BIOFUELS, 2018
Concomitant cell-free biosynthesis of optically pure D-(-)-acetoin and xylitol via a novel NAD(+) regeneration in two-enzyme cascade, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2018
Model-based reconstruction of synthetic promoter library in Corynebacterium glutamicum, BIOTECHNOLOGY LETTERS, 2018
Recent progress in microbial production of 3-hydroxypropionic acid, 化工进展, 2018
Recent advances for microbial production of diacetyl, 生物加工过程, 2017
Effects of inactivation of acetate synthetic pathway genes and overexpression of NADH oxidase on acetoin production in Corynebacterium glutamicum, 微生物学通报, 2017
Systematic metabolic engineering of Corynebacterium glutamicum for the industrial-level production of optically pure D-(-)-acetoin, GREEN CHEMISTRY, 2017
Metabolic engineering of Corynebacterium glutamicum for efficient production of 5-aminolevulinic acid, BIOTECHNOLOGY AND BIOENGINEERING, 2016
Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production, BIOTECHNOLOGY FOR BIOFUELS, 2016
Development of a markerless gene replacement system in Corynebacterium glutamicum using upp as a counter-selection marker, BIOTECHNOLOGY LETTERS, 2015
Engineering microorganisms based on molecular evolutionary analysis: a succinate production case study, EVOLUTIONARY APPLICATIONS, 2014
Area of Focus
Metagenomics | Algorithms | Microbiome | Drug Development | Eukaryotic Evolution | Traditional Chinese Medicine | Systems Biology | Computational Chemistry | Bioinformatics | Pharmacogenomics
