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Mao Yufeng
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Automated Design
Engineering Strains
Metabolic Engineering
Systems Biology
Multi-Gene Editing
High-Throughput Screening
Synthetic Biology
Genetic Manipulation
Biochemical Engineering
Bioinformatics
Areas of Focus
- Automated Design and Construction of Engineering Strains
- Metabolic Engineering and Systems Biology
- Multi-gene Simultaneous Editing Technology
Work Experience
- 2022-07 to Present - Chinese Academy of Sciences Tianjin Institute of Industrial Biotechnology - Associate Researcher
- 2018-07 to 2022-07 - Chinese Academy of Sciences Tianjin Institute of Industrial Biotechnology - Postdoctoral Researcher
- 2011-09 to 2018-06 - Tianjin University - Master's and Ph.D. in Biochemical Engineering
- 2007-09 to 2011-06 - Tianjin University - Bachelor's in Bioengineering
Academic Background & Achievements
- 2011-09 to 2018-06 Master's and Ph.D. in Biochemical Engineering: Tianjin University
- 2007-09 to 2011-06 Bachelor's in Bioengineering: Tianjin University
Publications
- Automated characterization and analysis of expression compatibility between regulatory sequences and metabolic genes in Escherichia coli, Synthetic and Systems Biotechnology, 2024
- Construction of L-phenylalanine High-producing Corynebacterium glutamicum Engineered Strains via Multi-gene Simultaneous Regulation Combined with High-throughput Screening, 生物技术通报, 2023
- ecBSU1: A Genome-Scale Enzyme-Constrained Model of Bacillus subtilis Based on the ECMpy Workflow, MICROORGANISMS, 2023
- Reconstruction of a Genome-Scale Metabolic Network for Shewanella oneidensis MR-1 and Analysis of its Metabolic Potential for Bioelectrochemical Systems, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022
- Construction and Analysis of an Enzyme-Constrained Metabolic Model of Corynebacterium glutamicum, BIOMOLECULES, 2022
- Global Cellular Metabolic Rewiring Adapts Corynebacterium glutamicum to Efficient Nonnatural Xylose Utilization, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2022
- Advances in automated high-throughput editing and screening of engineered strains, 生物工程学报, 2022
- Enhanced 3-Hydroxypropionic Acid Production From Acetate via the Malonyl-CoA Pathway in Corynebacterium glutamicum, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022
- Recent progress in ergothioneine biosynthesis: a review, 生物工程学报, 2022
- Natural 5-Aminolevulinic Acid: Sources, Biosynthesis, Detection and Applications, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022
- 面向微生物遗传操作的编辑序列设计工具的研究进展, 合成生物学, 2022
- AutoESD: a web tool for automatic editing sequence design for genetic manipulation of microorganisms, NUCLEIC ACIDS RESEARCH, 2022
- Advances in biotechnological production of beta-alanine, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2021
- GEDpm-cg: Genome Editing Automated Design Platform for Point Mutation Construction in Corynebacterium glutamicum, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021
- Non-natural Aldol Reactions Enable the Design and Construction of Novel One-Carbon Assimilation Pathways in vitro, FRONTIERS IN MICROBIOLOGY, 2021
- Engineering central pathways for industrial-level (3 R )-acetoin biosynthesis in Corynebacterium glutamicum, MICROBIAL CELL FACTORIES, 2020
- Substrate profiling and tolerance testing of Halomonas TD01 suggest its potential application in sustainable manufacturing of chemicals, JOURNAL OF BIOTECHNOLOGY, 2020
- One-pot efficient biosynthesis of (3R)-acetoin from pyruvate by a two-enzyme cascade, CATALYSIS SCIENCE & TECHNOLOGY, 2020
- Efficient solid-state fermentation for the production of 5-aminolevulinic acid enriched feed using recombinant Saccharomyces cerevisiae, JOURNAL OF BIOTECHNOLOGY, 2020
- Engineering Corynebacterium glutamicum for the Efficient Production of 3-Hydroxypropionic Acid from a Mixture of Glucose and Acetate via the Malonyl-CoA Pathway, CATALYSTS, 2020
- In vitro biosynthesis of optically pure d-(-)-acetoin from meso-2,3-butanediol using 2,3-butanediol dehydrogenase and NADH oxidase, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2019
- Screening, expression, purification and characterization of CoA-transferases for lactoyl-CoA generation, JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2019
- Systematic design and in vitro validation of novel one-carbon assimilation pathways, METABOLIC ENGINEERING, 2019
- Metabolic engineering of Corynebacterium glutamicum for efficient production of succinate from lignocellulosic hydrolysate, BIOTECHNOLOGY FOR BIOFUELS, 2018
- Concomitant cell-free biosynthesis of optically pure D-(-)-acetoin and xylitol via a novel NAD(+) regeneration in two-enzyme cascade, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2018
- Model-based reconstruction of synthetic promoter library in Corynebacterium glutamicum, BIOTECHNOLOGY LETTERS, 2018
- Recent progress in microbial production of 3-hydroxypropionic acid, 化工进展, 2018
- Recent advances for microbial production of diacetyl, 生物加工过程, 2017
- Effects of inactivation of acetate synthetic pathway genes and overexpression of NADH oxidase on acetoin production in Corynebacterium glutamicum, 微生物学通报, 2017
- Systematic metabolic engineering of Corynebacterium glutamicum for the industrial-level production of optically pure D-(-)-acetoin, GREEN CHEMISTRY, 2017
- Metabolic engineering of Corynebacterium glutamicum for efficient production of 5-aminolevulinic acid, BIOTECHNOLOGY AND BIOENGINEERING, 2016
- Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production, BIOTECHNOLOGY FOR BIOFUELS, 2016
- Development of a markerless gene replacement system in Corynebacterium glutamicum using upp as a counter-selection marker, BIOTECHNOLOGY LETTERS, 2015
- Engineering microorganisms based on molecular evolutionary analysis: a succinate production case study, EVOLUTIONARY APPLICATIONS, 2014
Awards
- Chinese Academy of Sciences Fourth 'Koyuan Craftsman' (Team) (2023)
