Professor | Xiaofeng Ma | Asia Growth Partners

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Name	Xiaofeng Ma
Contact Information	maxiaofeng@ucas.ac.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Xiaofeng Ma

Contact Information

maxiaofeng@ucas.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2000-09 to 2003-07: PhD, Shenyang Pharmaceutical University 1997-09 to 2000-07: Master's, Liaoning University of Traditional Chinese Medicine 1993-09 to 1997-07: Bachelor's, Shenyang Pharmaceutical University
Work Experience	2015-02 to 2016-02: Visiting Scholar, National Institutes of Health 2006-06 to 2011-06: Associate Professor, Graduate University of Chinese Academy of Sciences 2005-06 to 2006-06: Lecturer, Graduate University of Chinese Academy of Sciences 2003-09 to 2005-05: Postdoctoral Researcher, Graduate University of Chinese Academy of Sciences
Awards	2013: Outstanding Member, Youth Innovation Promotion Association, Chinese Academy of Sciences 2012: Second Prize, Scientific and Technological Progress Award, Ministry of Education 2011: Youth Innovation Promotion Association, Chinese Academy of Sciences 2010: Lu Jiaxi Young Talent Award, Chinese Academy of Sciences 2008: First Prize, Li Shizhen Medical Innovation Award, Chinese Association of Traditional Chinese Medicine 2008: Third Prize, Beijing Science and Technology Award

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2000-09 to 2003-07: PhD, Shenyang Pharmaceutical University
1997-09 to 2000-07: Master's, Liaoning University of Traditional Chinese Medicine
1993-09 to 1997-07: Bachelor's, Shenyang Pharmaceutical University

Work Experience

2015-02 to 2016-02: Visiting Scholar, National Institutes of Health
2006-06 to 2011-06: Associate Professor, Graduate University of Chinese Academy of Sciences
2005-06 to 2006-06: Lecturer, Graduate University of Chinese Academy of Sciences
2003-09 to 2005-05: Postdoctoral Researcher, Graduate University of Chinese Academy of Sciences

Awards

2013: Outstanding Member, Youth Innovation Promotion Association, Chinese Academy of Sciences
2012: Second Prize, Scientific and Technological Progress Award, Ministry of Education
2011: Youth Innovation Promotion Association, Chinese Academy of Sciences
2010: Lu Jiaxi Young Talent Award, Chinese Academy of Sciences
2008: First Prize, Li Shizhen Medical Innovation Award, Chinese Association of Traditional Chinese Medicine
2008: Third Prize, Beijing Science and Technology Award

Areas of Focus	Natural Product Chemistry Enzymology
Publications	Alpha-Linolenic Acid Suppresses Proliferation and Invasion in Osteosarcoma Cells via Inhibiting Fatty Acid Synthase, Huijin Fan, Wenyuan Huang, Yong Guo, Xiaofeng Ma, Jianhong Yang, 2022 α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase, Wenyuan Huang, Xing Guo, Chunyan Wang, Zhengan Liu, Xiaofeng Ma, Qingyan Shu, 2022 ?-Mangostin suppresses proliferation and invasion in osteosarcoma cells via inhibiting fatty acid synthase, Fan, Huijin, Guo, Yong, Zhang, Yaonan, Ding, Ning, Liu, Meiling, Ma, Xiaofeng, Yang, Jianhong, 2022 Inhibitory Effect of Acer truncatum Bunge Seed Coat Extract on Fatty Acid Synthase, Differentiation and Lipid Accumulation in 3T3-L1 Adipocytes, Yan Liang, Fan Kong, Xiaofeng Ma, Qingyan Shu, 2022 Traditional Chinese Medicines With Anti-inflammatory Functions and Their Inhibitory Effects on Fatty Acid Synthase, Huang WenYuan, Wang HongJun, Alzhan, Amantay, Tian WeiXi, Ma XiaoFeng, 2020 Vitisin B as a novel fatty acid synthase inhibitor induces human breast cancer cells apoptosis, Wang, Xiaoyan, Jiang, Bing, Lv, Huanhuan, Liang, Yan, Ma, Xiaofeng, 2019 Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells, Huang, Wenyuan, Liang, Yan, Ma, Xiaofeng, 2019 Phenolic Compounds from Mangifera indica, Jiang, Hezhong, Yuan, Juanjuan, Ma, Qingyun, Ma, Xiaofeng, Zhao, Youxing, 2019 1, 3, 6-Trihydroxy-7-Methyl-9, 10-Anthracenedione Isolated from genus Lindera with Anti-Cancer Activity, Wei, Guoqing, Chen, Hui, Nie, Fangyuan, Ma, Xiaofeng, Jiang, Hezhong, 2017 Apoptotic effect of tannic acid on fatty acid synthase over-expressed human breast cancer cells, Nie, Fangyuan, Liang, Yan, Jiang, Bing, Li, Xiabing, Xun, Hang, He, Wei, Lau, Hay Tong, Ma, Xiaofeng, 2016 Curcumin inhibits intracellular fatty acid synthase and induces apoptosis in human breast cancer MDA-MB-231 cells, Fan, Huijin, Liang, Yan, Jiang, Bing, Li, Xiabing, Xun, Hang, Sun, Jia, He, Wei, Lau, Hay Tong, Ma, Xiaofeng, 2016 Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis, Wei Cui, Yan Liang, Weixi Tian, Mingjuan Ji, Xiaofeng Ma, 2016 Potent Inhibitory Effect of Chinese Dietary Spices on Fatty Acid Synthase, Jiang, Bing, Liang, Yan, Sun, Xuebing, Liu, Xiaoxin, Tian, Weixi, Ma, Xiaofeng, 2015 Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase, Zhang, Qiulong, Luan, Guangxiang, Ma, Tao, Hu, Na, Suo, Yourui, Wang, Xiaoyan, Ma, Xiaofeng, Ding, Chenxu, 2015 Inhibitory effects of tannic acid in the early stage of 3T3-L1 preadipocytes differentiation by down-regulating PPAR gamma expression, Nie, Fangyuan, Liang, Yan, Xun, Hang, Sun, Jia, He, Fei, Ma, Xiaofeng, 2015 New analytical spiral tube assembly for separation of proteins by counter-current chromatography, Ma, Xiaofeng, Ito, Yoichiro, 2015 Curcumin induces apoptosis of HepG2 cells via inhibiting fatty acid synthase, Fan, Huijin, Tian, Weixi, Ma, Xiaofeng, 2014 Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells, Li, Ping, Tian, Weixi, Ma, Xiaofeng, 2014 Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan medicinal plant Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells, Ma Xiaofeng, 2014 Inhibitory effects of sea buckthorn procyanidins on fatty acid synthase and MDA-MB-231 cells, Wang, Yi, Nie, Fangyuan, Ouyang, Jian, Wang, Xiaoyan, Ma, Xiaofeng, 2014 Inhibitory effects of grape skin extract and resveratrol on fatty acid synthase, Xiaofeng Ma, Weixi Tian, Yan Liang, 2013 Inhibitory effects of tannic acid on fatty acid synthase and 3T3-L1 preadipocyte, Fan, Huijin, Wu, Dan, Tian, Weixi, Ma, Xiaofeng, 2013 Pomegranate husk extract, punicalagin and ellagic acid inhibit fatty acid synthase and adipogenesis of 3T3-L1 adipocyte, Wu, Dan, Ma, Xiaofeng, Tian, Weixi, 2013 中药寒热相关药性和抑制脂肪酸合酶能力关系的探索, 马晓丰, 刘杨, 张三国, 陈传楚, 田维熙, 2012 A new furostanol glycoside with fatty acid synthase inhibitory activity from Ophiopogon japonicas, Ma Xiaofeng, 2012 氧杂蒽酮对脂肪酸合酶的抑制作用及构效分析, 权小芳, 马晓丰, 2012 Inhibitory Effects of Onion (Allium cepa L.) Extract on Proliferation of Cancer Cells and Adipocytes via Inhibiting Fatty Acid Synthase, Wang, Yi, Tian, WeiXi, Ma, XiaoFeng, 2012 熊果酸抑制脂肪酸合酶及诱导HepG2细胞凋亡机制研究, 樊慧锦, 田维熙, 马晓丰, 2012 alpha-Mangostin Induces Apoptosis and Suppresses Differentiation of 3T3-L1 Cells via Inhibiting Fatty Acid Synthase, Quan, Xiaofang, Wang, Yi, Ma, Xiaofeng, Liang, Yan, Tian, Weixi, Ma, Qingyun, Jiang, Hezhong, Zhao, Youxing, 2012 Fatty Acid Synthase Inhibitors Isolated from Punica granatum L., Jiang, HeZhong, Ma, QingYun, Fan, HuiJin, Liang, WenJuan, Huang, ShengZhuo, Dai, HaoFu, Wang, PengCheng, Ma, XiaoFeng, Zhao, YouXing, 2012 Fatty Acid Synthase Inhibitors Separated from Oiltea Camellia by High-Speed Counter-Current Chromatography, Chen, Qiuping, Luo, Xiaowei, Ma, Xiaofeng, Jiang, Tianjia, Lu, Baiyi, Shen, Jianfu, Zhang, Ying, 2011 Fatty acid synthase inhibitors from the hulls of Nephelium lappaceum L., Zhao, YouXing, Liang, WenJuan, Fan, HuiJin, Ma, QingYun, Tian, WeiXi, Dai, HaoFu, Jiang, HeZhong, Li, Ning, Ma, XiaoFeng, 2011 Fatty acid synthase inhibitors from plants and their potential application in the prevention of metabolic syndrome, Weixi Tian, Xiaofeng Ma, Shuyan Zhang, Yinghui Sun, Binghui Li, 2011 Discovery of novel fatty acid synthase (FAS) inhibitors based on the structure of ketoaceyl synthase (KS) domain, Zeng, XiaoFei, Li, WeiWei, Fan, HuiJin, Wang, XiaoYan, Ji, Pan, Wang, ZeRong, Ma, Shuang, Li, LinLi, Ma, XiaoFeng, Yang, ShengYong, 2011

Areas of Focus

Natural Product Chemistry
Enzymology

Publications

Alpha-Linolenic Acid Suppresses Proliferation and Invasion in Osteosarcoma Cells via Inhibiting Fatty Acid Synthase, Huijin Fan, Wenyuan Huang, Yong Guo, Xiaofeng Ma, Jianhong Yang, 2022
α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase, Wenyuan Huang, Xing Guo, Chunyan Wang, Zhengan Liu, Xiaofeng Ma, Qingyan Shu, 2022
?-Mangostin suppresses proliferation and invasion in osteosarcoma cells via inhibiting fatty acid synthase, Fan, Huijin, Guo, Yong, Zhang, Yaonan, Ding, Ning, Liu, Meiling, Ma, Xiaofeng, Yang, Jianhong, 2022
Inhibitory Effect of Acer truncatum Bunge Seed Coat Extract on Fatty Acid Synthase, Differentiation and Lipid Accumulation in 3T3-L1 Adipocytes, Yan Liang, Fan Kong, Xiaofeng Ma, Qingyan Shu, 2022
Traditional Chinese Medicines With Anti-inflammatory Functions and Their Inhibitory Effects on Fatty Acid Synthase, Huang WenYuan, Wang HongJun, Alzhan, Amantay, Tian WeiXi, Ma XiaoFeng, 2020
Vitisin B as a novel fatty acid synthase inhibitor induces human breast cancer cells apoptosis, Wang, Xiaoyan, Jiang, Bing, Lv, Huanhuan, Liang, Yan, Ma, Xiaofeng, 2019
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells, Huang, Wenyuan, Liang, Yan, Ma, Xiaofeng, 2019
Phenolic Compounds from Mangifera indica, Jiang, Hezhong, Yuan, Juanjuan, Ma, Qingyun, Ma, Xiaofeng, Zhao, Youxing, 2019
1, 3, 6-Trihydroxy-7-Methyl-9, 10-Anthracenedione Isolated from genus Lindera with Anti-Cancer Activity, Wei, Guoqing, Chen, Hui, Nie, Fangyuan, Ma, Xiaofeng, Jiang, Hezhong, 2017
Apoptotic effect of tannic acid on fatty acid synthase over-expressed human breast cancer cells, Nie, Fangyuan, Liang, Yan, Jiang, Bing, Li, Xiabing, Xun, Hang, He, Wei, Lau, Hay Tong, Ma, Xiaofeng, 2016
Curcumin inhibits intracellular fatty acid synthase and induces apoptosis in human breast cancer MDA-MB-231 cells, Fan, Huijin, Liang, Yan, Jiang, Bing, Li, Xiabing, Xun, Hang, Sun, Jia, He, Wei, Lau, Hay Tong, Ma, Xiaofeng, 2016
Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis, Wei Cui, Yan Liang, Weixi Tian, Mingjuan Ji, Xiaofeng Ma, 2016
Potent Inhibitory Effect of Chinese Dietary Spices on Fatty Acid Synthase, Jiang, Bing, Liang, Yan, Sun, Xuebing, Liu, Xiaoxin, Tian, Weixi, Ma, Xiaofeng, 2015
Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase, Zhang, Qiulong, Luan, Guangxiang, Ma, Tao, Hu, Na, Suo, Yourui, Wang, Xiaoyan, Ma, Xiaofeng, Ding, Chenxu, 2015
Inhibitory effects of tannic acid in the early stage of 3T3-L1 preadipocytes differentiation by down-regulating PPAR gamma expression, Nie, Fangyuan, Liang, Yan, Xun, Hang, Sun, Jia, He, Fei, Ma, Xiaofeng, 2015
New analytical spiral tube assembly for separation of proteins by counter-current chromatography, Ma, Xiaofeng, Ito, Yoichiro, 2015
Curcumin induces apoptosis of HepG2 cells via inhibiting fatty acid synthase, Fan, Huijin, Tian, Weixi, Ma, Xiaofeng, 2014
Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells, Li, Ping, Tian, Weixi, Ma, Xiaofeng, 2014
Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan medicinal plant Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells, Ma Xiaofeng, 2014
Inhibitory effects of sea buckthorn procyanidins on fatty acid synthase and MDA-MB-231 cells, Wang, Yi, Nie, Fangyuan, Ouyang, Jian, Wang, Xiaoyan, Ma, Xiaofeng, 2014
Inhibitory effects of grape skin extract and resveratrol on fatty acid synthase, Xiaofeng Ma, Weixi Tian, Yan Liang, 2013
Inhibitory effects of tannic acid on fatty acid synthase and 3T3-L1 preadipocyte, Fan, Huijin, Wu, Dan, Tian, Weixi, Ma, Xiaofeng, 2013
Pomegranate husk extract, punicalagin and ellagic acid inhibit fatty acid synthase and adipogenesis of 3T3-L1 adipocyte, Wu, Dan, Ma, Xiaofeng, Tian, Weixi, 2013
中药寒热相关药性和抑制脂肪酸合酶能力关系的探索, 马晓丰, 刘杨, 张三国, 陈传楚, 田维熙, 2012
A new furostanol glycoside with fatty acid synthase inhibitory activity from Ophiopogon japonicas, Ma Xiaofeng, 2012
氧杂蒽酮对脂肪酸合酶的抑制作用及构效分析, 权小芳, 马晓丰, 2012
Inhibitory Effects of Onion (Allium cepa L.) Extract on Proliferation of Cancer Cells and Adipocytes via Inhibiting Fatty Acid Synthase, Wang, Yi, Tian, WeiXi, Ma, XiaoFeng, 2012
熊果酸抑制脂肪酸合酶及诱导HepG2细胞凋亡机制研究, 樊慧锦, 田维熙, 马晓丰, 2012
alpha-Mangostin Induces Apoptosis and Suppresses Differentiation of 3T3-L1 Cells via Inhibiting Fatty Acid Synthase, Quan, Xiaofang, Wang, Yi, Ma, Xiaofeng, Liang, Yan, Tian, Weixi, Ma, Qingyun, Jiang, Hezhong, Zhao, Youxing, 2012
Fatty Acid Synthase Inhibitors Isolated from Punica granatum L., Jiang, HeZhong, Ma, QingYun, Fan, HuiJin, Liang, WenJuan, Huang, ShengZhuo, Dai, HaoFu, Wang, PengCheng, Ma, XiaoFeng, Zhao, YouXing, 2012
Fatty Acid Synthase Inhibitors Separated from Oiltea Camellia by High-Speed Counter-Current Chromatography, Chen, Qiuping, Luo, Xiaowei, Ma, Xiaofeng, Jiang, Tianjia, Lu, Baiyi, Shen, Jianfu, Zhang, Ying, 2011
Fatty acid synthase inhibitors from the hulls of Nephelium lappaceum L., Zhao, YouXing, Liang, WenJuan, Fan, HuiJin, Ma, QingYun, Tian, WeiXi, Dai, HaoFu, Jiang, HeZhong, Li, Ning, Ma, XiaoFeng, 2011
Fatty acid synthase inhibitors from plants and their potential application in the prevention of metabolic syndrome, Weixi Tian, Xiaofeng Ma, Shuyan Zhang, Yinghui Sun, Binghui Li, 2011
Discovery of novel fatty acid synthase (FAS) inhibitors based on the structure of ketoaceyl synthase (KS) domain, Zeng, XiaoFei, Li, WeiWei, Fan, HuiJin, Wang, XiaoYan, Ji, Pan, Wang, ZeRong, Ma, Shuang, Li, LinLi, Ma, XiaoFeng, Yang, ShengYong, 2011

Natural Products Fatty Acid Synthase Inhibitors Structure Biological Function Enzymes Mechanism Of Action Inhibition Fat Cells Biochemistry Molecular Biology

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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