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Xiaofeng Ma
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Natural Products
Fatty Acid Synthase Inhibitors
Structure
Biological Function
Enzymes
Mechanism Of Action
Inhibition
Fat Cells
Biochemistry
Molecular Biology
Areas of Focus
- Natural Product Chemistry
- Enzymology
Work Experience
- 2015-02 to 2016-02: Visiting Scholar, National Institutes of Health
- 2006-06 to 2011-06: Associate Professor, Graduate University of Chinese Academy of Sciences
- 2005-06 to 2006-06: Lecturer, Graduate University of Chinese Academy of Sciences
- 2003-09 to 2005-05: Postdoctoral Researcher, Graduate University of Chinese Academy of Sciences
Academic Background & Achievements
- 2000-09 to 2003-07: PhD, Shenyang Pharmaceutical University
- 1997-09 to 2000-07: Master's, Liaoning University of Traditional Chinese Medicine
- 1993-09 to 1997-07: Bachelor's, Shenyang Pharmaceutical University
Publications
- Alpha-Linolenic Acid Suppresses Proliferation and Invasion in Osteosarcoma Cells via Inhibiting Fatty Acid Synthase, Huijin Fan, Wenyuan Huang, Yong Guo, Xiaofeng Ma, Jianhong Yang, 2022
- α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase, Wenyuan Huang, Xing Guo, Chunyan Wang, Zhengan Liu, Xiaofeng Ma, Qingyan Shu, 2022
- ?-Mangostin suppresses proliferation and invasion in osteosarcoma cells via inhibiting fatty acid synthase, Fan, Huijin, Guo, Yong, Zhang, Yaonan, Ding, Ning, Liu, Meiling, Ma, Xiaofeng, Yang, Jianhong, 2022
- Inhibitory Effect of Acer truncatum Bunge Seed Coat Extract on Fatty Acid Synthase, Differentiation and Lipid Accumulation in 3T3-L1 Adipocytes, Yan Liang, Fan Kong, Xiaofeng Ma, Qingyan Shu, 2022
- Traditional Chinese Medicines With Anti-inflammatory Functions and Their Inhibitory Effects on Fatty Acid Synthase, Huang WenYuan, Wang HongJun, Alzhan, Amantay, Tian WeiXi, Ma XiaoFeng, 2020
- Vitisin B as a novel fatty acid synthase inhibitor induces human breast cancer cells apoptosis, Wang, Xiaoyan, Jiang, Bing, Lv, Huanhuan, Liang, Yan, Ma, Xiaofeng, 2019
- Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells, Huang, Wenyuan, Liang, Yan, Ma, Xiaofeng, 2019
- Phenolic Compounds from Mangifera indica, Jiang, Hezhong, Yuan, Juanjuan, Ma, Qingyun, Ma, Xiaofeng, Zhao, Youxing, 2019
- 1, 3, 6-Trihydroxy-7-Methyl-9, 10-Anthracenedione Isolated from genus Lindera with Anti-Cancer Activity, Wei, Guoqing, Chen, Hui, Nie, Fangyuan, Ma, Xiaofeng, Jiang, Hezhong, 2017
- Apoptotic effect of tannic acid on fatty acid synthase over-expressed human breast cancer cells, Nie, Fangyuan, Liang, Yan, Jiang, Bing, Li, Xiabing, Xun, Hang, He, Wei, Lau, Hay Tong, Ma, Xiaofeng, 2016
- Curcumin inhibits intracellular fatty acid synthase and induces apoptosis in human breast cancer MDA-MB-231 cells, Fan, Huijin, Liang, Yan, Jiang, Bing, Li, Xiabing, Xun, Hang, Sun, Jia, He, Wei, Lau, Hay Tong, Ma, Xiaofeng, 2016
- Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis, Wei Cui, Yan Liang, Weixi Tian, Mingjuan Ji, Xiaofeng Ma, 2016
- Potent Inhibitory Effect of Chinese Dietary Spices on Fatty Acid Synthase, Jiang, Bing, Liang, Yan, Sun, Xuebing, Liu, Xiaoxin, Tian, Weixi, Ma, Xiaofeng, 2015
- Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase, Zhang, Qiulong, Luan, Guangxiang, Ma, Tao, Hu, Na, Suo, Yourui, Wang, Xiaoyan, Ma, Xiaofeng, Ding, Chenxu, 2015
- Inhibitory effects of tannic acid in the early stage of 3T3-L1 preadipocytes differentiation by down-regulating PPAR gamma expression, Nie, Fangyuan, Liang, Yan, Xun, Hang, Sun, Jia, He, Fei, Ma, Xiaofeng, 2015
- New analytical spiral tube assembly for separation of proteins by counter-current chromatography, Ma, Xiaofeng, Ito, Yoichiro, 2015
- Curcumin induces apoptosis of HepG2 cells via inhibiting fatty acid synthase, Fan, Huijin, Tian, Weixi, Ma, Xiaofeng, 2014
- Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells, Li, Ping, Tian, Weixi, Ma, Xiaofeng, 2014
- Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan medicinal plant Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells, Ma Xiaofeng, 2014
- Inhibitory effects of sea buckthorn procyanidins on fatty acid synthase and MDA-MB-231 cells, Wang, Yi, Nie, Fangyuan, Ouyang, Jian, Wang, Xiaoyan, Ma, Xiaofeng, 2014
- Inhibitory effects of grape skin extract and resveratrol on fatty acid synthase, Xiaofeng Ma, Weixi Tian, Yan Liang, 2013
- Inhibitory effects of tannic acid on fatty acid synthase and 3T3-L1 preadipocyte, Fan, Huijin, Wu, Dan, Tian, Weixi, Ma, Xiaofeng, 2013
- Pomegranate husk extract, punicalagin and ellagic acid inhibit fatty acid synthase and adipogenesis of 3T3-L1 adipocyte, Wu, Dan, Ma, Xiaofeng, Tian, Weixi, 2013
- 中药寒热相关药性和抑制脂肪酸合酶能力关系的探索, 马晓丰, 刘杨, 张三国, 陈传楚, 田维熙, 2012
- A new furostanol glycoside with fatty acid synthase inhibitory activity from Ophiopogon japonicas, Ma Xiaofeng, 2012
- 氧杂蒽酮对脂肪酸合酶的抑制作用及构效分析, 权小芳, 马晓丰, 2012
- Inhibitory Effects of Onion (Allium cepa L.) Extract on Proliferation of Cancer Cells and Adipocytes via Inhibiting Fatty Acid Synthase, Wang, Yi, Tian, WeiXi, Ma, XiaoFeng, 2012
- 熊果酸抑制脂肪酸合酶及诱导HepG2细胞凋亡机制研究, 樊慧锦, 田维熙, 马晓丰, 2012
- alpha-Mangostin Induces Apoptosis and Suppresses Differentiation of 3T3-L1 Cells via Inhibiting Fatty Acid Synthase, Quan, Xiaofang, Wang, Yi, Ma, Xiaofeng, Liang, Yan, Tian, Weixi, Ma, Qingyun, Jiang, Hezhong, Zhao, Youxing, 2012
- Fatty Acid Synthase Inhibitors Isolated from Punica granatum L., Jiang, HeZhong, Ma, QingYun, Fan, HuiJin, Liang, WenJuan, Huang, ShengZhuo, Dai, HaoFu, Wang, PengCheng, Ma, XiaoFeng, Zhao, YouXing, 2012
- Fatty Acid Synthase Inhibitors Separated from Oiltea Camellia by High-Speed Counter-Current Chromatography, Chen, Qiuping, Luo, Xiaowei, Ma, Xiaofeng, Jiang, Tianjia, Lu, Baiyi, Shen, Jianfu, Zhang, Ying, 2011
- Fatty acid synthase inhibitors from the hulls of Nephelium lappaceum L., Zhao, YouXing, Liang, WenJuan, Fan, HuiJin, Ma, QingYun, Tian, WeiXi, Dai, HaoFu, Jiang, HeZhong, Li, Ning, Ma, XiaoFeng, 2011
- Fatty acid synthase inhibitors from plants and their potential application in the prevention of metabolic syndrome, Weixi Tian, Xiaofeng Ma, Shuyan Zhang, Yinghui Sun, Binghui Li, 2011
- Discovery of novel fatty acid synthase (FAS) inhibitors based on the structure of ketoaceyl synthase (KS) domain, Zeng, XiaoFei, Li, WeiWei, Fan, HuiJin, Wang, XiaoYan, Ji, Pan, Wang, ZeRong, Ma, Shuang, Li, LinLi, Ma, XiaoFeng, Yang, ShengYong, 2011
Awards
- 2013: Outstanding Member, Youth Innovation Promotion Association, Chinese Academy of Sciences
- 2012: Second Prize, Scientific and Technological Progress Award, Ministry of Education
- 2011: Youth Innovation Promotion Association, Chinese Academy of Sciences
- 2010: Lu Jiaxi Young Talent Award, Chinese Academy of Sciences
- 2008: First Prize, Li Shizhen Medical Innovation Award, Chinese Association of Traditional Chinese Medicine
- 2008: Third Prize, Beijing Science and Technology Award
