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Qiang Sun
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Non-Human Primate
Model Construction
Reproductive Endocrine
Animal Model
Somatic Cell Reprogramming
Transgenic
Gene Editing
Mammals
Neuroscience
Biotechnology
Areas of Focus
- Non-human primate model construction and related technologies
- Reproductive endocrine regulation and related animal model development
- Somatic cell reprogramming in non-human primates
- Transgenic and gene editing technologies in mammals
Work Experience
- 2018-02~Present - Institute of Neuroscience, Chinese Academy of Sciences - Researcher
- 2009-06~2018-01 - Institute of Neuroscience, Chinese Academy of Sciences - Senior Engineer
- 2005-09~2009-05 - East China Normal University - Associate Researcher
- 2002-09~2005-06 - Shanghai Institute of Pharmaceutical Industry - PhD
- 1999-07~2005-08 - Yangzhou University College of Veterinary Medicine - Lecturer
Academic Background & Achievements
- 2002-09--2005-06 PhD: Shanghai Institute of Pharmaceutical Industry
- 1996-09--1999-06 Master's: Yangzhou University College of Veterinary Medicine
- 1992-09--1996-06 Bachelor's: Inner Mongolia Zhelimu Animal Husbandry College
Publications
- Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys, 5th Author, 2023
- Cynomolgus monkey embryo model captures gastrulation and early pregnancy, 23rd Author, 2023
- Base-edited cynomolgus monkeys mimic core symptoms of STXBP1 encephalopathy, 11th Author, 2022
- Epigenetic manipulation to improve mouse SCNT embryonic development, 11th Author, 2022
- Characterization of gut microbial alterations in cynomolgus macaques during growth and maturation, 11th Author, 2022
- Accelerated passage of gene-modified monkeys by hormone-induced precocious puberty, 11th Author, 2021
- Mitochondrial replacement in macaque monkey offspring by first polar body transfer, 13th Author, 2021
- Modeling a cataract disorder in mice with prime editing, 11th Author, 2021
- Mitochondrial replacement in macaque monkey offspring by first polar body transfer, 11th Author, 2021
- Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin, 7th Author, 2020
- Efficient and risk-reduced genome editing using double nicks enhanced by bacterial recombination factors in multiple species, 11th Author, 2020
- Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice, 11th Author, 2020
- Single-cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis), 11th Author, 2020
- A pannexin 1 channelopathy causes human oocyte death, 18th Author, 2019
- Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer, 16th Author, 2019
- BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders, 14th Author, 2019
- Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes, 6th Author, 2019
- Age-related nomograms of serum anti-Mullerian hormone levels in female monkeys: Comparison of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) monkeys, 11th Author, 2018
- Serum anti-Mullerian hormone predicts ovarian response in (Macaca fascicularis) monkeys, 11th Author, 2018
- Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer, 11th Author, 2018
- Sleep and circadian abnormalities precede cognitive deficits in R521C FUS knockin rats, 11th Author, 2018
- Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing, 11th Author, 2018
- Reduction of HIP2 expression causes motor function impairment and increased vulnerability to dopaminergic degeneration in Parkinson's disease models, 13th Author, 2018
- Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing, 11th Author, 2018
- Homology-mediated end joining-based targeted integration using crispr/cas9, 11th Author, 2017
- One-step generation of complete gene knockout mice and monkeys by crispr/cas9-mediated gene editing with multiple sgrnas, 11th Author, 2017
- Generation of macaques with sperm derived from juvenile monkey testicular xenografts, 11th Author, 2016
- Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2, 11th Author, 2016
- Generation of a monkey with MECP2 mutations by TALEN-based gene targeting, 14th Author, 2014
- Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes, 17th Author, 2013
- Efficient reproduction of cynomolgus monkey using pronuclear embryo transfer technique, 11th Author, 2008
Awards
- Shanghai Science and Technology Award (2022): First Prize
- WuXi AppTec Life Chemistry Research Award (2020): First Prize
- Tan Jiazhen Life Science Innovation Award (2018): First Prize
- Top Ten Scientific Advances in China (2018): First Prize
- Young and Middle-aged Leading Talents in Science and Technology Innovation by Ministry of Science and Technology (2018): First Prize
- Top Ten Scientific Advances in China (2016): First Prize
- Top Ten Advances in Life Sciences in China (2016): First Prize
