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Yongyong Shi
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Schizophrenia
Brain Diseases
Genetics
Neuroscience
Mental Health
Psychiatric Disorders
Genomic Analysis
Neurobiology
Bioinformatics
Disease Mechanisms
Areas of Focus
- Schizophrenia and Brain Diseases
Work Experience
- 2023-06~Present - Chinese Academy of Sciences, Institute of Neuroscience - Deputy Director
- 2022-07~Present - Shanghai Jiao Tong University, Bio-X Institute - Director
- 2019-01~2022-06 - Shanghai Jiao Tong University, Bio-X Institute - Deputy Director & Executive Director
- 2019-01~2023-05 - Shanghai Jiao Tong University, School of Life Sciences - Deputy Director
- 2014-01~Present - Shanghai Jiao Tong University - Distinguished Professor
- 2008-02~2013-12 - Shanghai Jiao Tong University - Researcher
- 2006-06~2008-01 - Shanghai Jiao Tong University - Associate Professor
Academic Background & Achievements
- 2001-09--2006-03 PhD: Shanghai Jiao Tong University
- 1997-09--2001-06 Bachelor of Science: Shanghai Jiao Tong University
Publications
- Highly accurate protein structure prediction and drug screen of monkeypox virus proteome, 5th Author, 2023
- Cancer Cells Enter an Adaptive Persistence to Survive Radiotherapy and Repopulate Tumor, 21st Author, 2023
- Whole-Exome Sequencing Reveals Distinct Genetic Profiles of Palindromic Rheumatism, 10th Author, 2023
- Multiomics Analyses Reveal Microbiome-Gut-Brain Crosstalk Centered on Aberrant Gamma-Aminobutyric Acid and Tryptophan Metabolism in Drug-Naïve Patients with First-Episode, 17th Author, 2023
- Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-related Traits Identifies Novel Risk Loci in Han Chinese Individuals, 25th Author, 2022
- Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants, 14th Author, 2022
- Cigarette smoking and schizophrenia: Mendelian randomisation study, 12th Author, 2021
- Structural Analysis of the SARS-CoV-2 Omicron Variant Proteins, 4th Author, 2021
- Both HLA class I and II regions identified as genome-wide significant susceptibility loci for adult-onset Still's disease in Chinese individuals, 37th Author, 2020
- Rare and common variants analysis of the EMB gene in patients with schizophrenia, 8th Author, 2020
- Discussion on the Safety and Ethical Issues of Medical Big Data, 3rd Author, 2019
- ACTN3 is associated with children's physical fitness in Han Chinese, 14th Author, 2019
- Amplicon targeted resequencing for SLC2A9 and SLC22A12 identified novel mutations in hypouricemia subjects, 15th Author, 2019
- Comparative genetic architectures of schizophrenia in East Asian and European populations, 11th Author, 2019
- Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese, 7th Author, 2019
- Identification of serum microRNAs as diagnostic biomarkers for schizophrenia, 8th Author, 2019
- INCREASING ANCESTRY DIVERSITY IN PSYCHIATRIC GENOMICS RESEARCH, 13th Author, 2019
- The schizophrenia genetics knowledgebase: a comprehensive update of findings from candidate gene studies, 19th Author, 2019
- Polymorphism of the PPARD Gene and Dynamic Balance Performance in Han Chinese Children, 15th Author, 2019
- Association study of NDST3 gene for schizophrenia, bipolar disorder, major depressive disorder in the Han Chinese population, 10th Author, 2018
- Biological data processing based on bio-processor unit (BPU), a new concept for next generation computational biology, 6th Author, 2018
- Meta-analysis of GABRB2 polymorphisms and the risk of schizophrenia combined with GWAS data of the Han Chinese population and psychiatric genomics consortium, 4th Author, 2018
- Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese, 32nd Author, 2018
- Identification of recurrent USP48 and BRAF mutations in Cushing's disease, 40th Author, 2018
- Significant Association of CD40-1C-T Polymorphism and Stroke in the Han Chinese Population, 7th Author, 2018
- Association between peroxisome proliferator-activated receptor, UCP3 and lipoprotein lipase gene polymorphisms and obesity in Chinese adolescents, 3rd Author, 2017
- Association between the variability of the ABCA13 gene and the risk of major depressive disorder and schizophrenia in the Han Chinese population, 12th Author, 2017
- META-ANALYSIS OF GENOME WIDE ASSOCIATION STUDIES SHOWED POLYMORPHISMS ON 2P16.1, 6P22.1 AND 10Q24.32 ASSOCIATED WITH SCHIZOPHRENIA IN CHINESE HAN POPULATION, 8th Author, 2017
- Genome-wide two-locus interaction analysis identifies multiple epistatic SNP pairs that confer risk of prostate cancer: A cross-population study, 5th Author, 2017
- Replication of Gout/Urate Concentrations GWAS Susceptibility Loci Associated with Gout in a Han Chinese Population, 24th Author, 2017
- Germline Mutations in CDH23, Encoding Cadherin-Related 23, Are Associated with Both Familial and Sporadic Pituitary Adenomas, 32nd Author, 2017
- The YWHAE gene confers risk to major depressive disorder in the male group of Chinese Han population, 9th Author, 2017
- An association between single nucleotide polymorphisms in the promoter region of alcohol dehydrogenase 1B and the risk of developing colorectal carcinoma in the Chinese Han population, 8th Author, 2017
- Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics, 23rd Author, 2017
- Associations of single nucleotide polymorphisms of UCP genes with diabetic retinopathy in Chinese Han population, 13th Author, 2017
- DNA origami-based shape IDs for single-molecule nanomechanical genotyping, 13th Author, 2017
- Consensus paper of the WFSBP Task Force on Genetics: Genetics, epigenetics and gene expression markers of major depressive disorder and antidepressant response, 25th Author, 2017
- Micro
Awards
- Shanghai Science and Technology Elite Award (2022): Provincial Level
- Second Prize for Key Gene Fine Mapping of Mental Disorders Based on Linkage Disequilibrium and Long Haplotype Analysis (2019): National Level
- First Prize for Key Gene Fine Mapping of Mental Disorders (2019): Ministerial Level
- Second Prize for the Creation of a Precision Intervention System for the Prevention and Treatment of Blinding Eye Diseases (2018): Ministerial Level
- Youth Science Award of the Ministry of Education (2016): Ministerial Level
- Shanghai Science and Technology Outstanding Contribution Award (2016): Provincial Level
- First Prize for Tumor Genetic Susceptibility Based on Genome-Wide Strategy (2015): Ministerial Level
- Ho Leung Ho Lee Foundation Award (2015): Other
- First Prize for the Design, Assembly, and Bioanalytical Application of Diverse and Collaborative Biosensing Interfaces (2014): Provincial Level
- Tan Jiazhen Science Innovation Award (2014): Other
- Young and Middle-aged Leading Talents in Science and Technology of the Ministry of Science and Technology (2014): Ministerial Level
- First Prize for Research and Application of Several Key Algorithms in the Genetic Mechanism of Complex Diseases (2013): Provincial Level
