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Yiming Shi
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English, German
Contact
Molecule Discovery Functional Characterization Natural Products Species Interactions Microbiome Biosynthesis Biochemistry Molecular Biology Synthetic Biology Bioinformatics
Areas of Focus
  • Active Molecule Discovery and Functional Characterization
  • Natural Product Mediated Species Interactions
  • Human Microbiome
Work Experience
  • 2021-03 to 2023-02 - Max Planck Institute for Terrestrial Microbiology - Project Group Leader
  • 2016-01 to 2021-02 - Goethe University Frankfurt - Postdoctoral Researcher
Academic Background & Achievements
  • 2009-09 to 2014-07 Ph.D.: Kunming Institute of Botany, Chinese Academy of Sciences
Publications
  • Cleavage Off-Loading and Post-assembly-Line Conversions Yield Products with Unusual Termini during Biosynthesis, Yiming Shi, 2022
  • Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate-Containing Natural Products in Diverse Bacteria, Yiming Shi, 2022
  • Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria, Yiming Shi, 2022
  • An Unconventional Melanin Biosynthesis Pathway in Ustilago maydis, Yiming Shi, 2021
  • Engineering bacterial symbionts of nematodes improves their biocontrol potential to counter the western corn rootworm, Yiming Shi, 2020
  • Engineering bacterial symbionts of nematodes improves biocontrol potential of the western corn rootworm, Yiming Shi, 2020
  • (+/-)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp., Yiming Shi, 2019
  • Expanding the Isoprenoid Building Block Repertoire with an IPP Methyltransferase from Streptomyces monomycini, Yiming Shi, 2019
  • CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria, Yiming Shi, 2019
  • An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments, Yiming Shi, 2019
  • Dual phenazine gene clusters enable diversification during biosynthesis, Yiming Shi, 2019
  • Chemical language and warfare of bacterial natural products in bacteria-nematode-insect interactions, Yiming Shi, 2018
  • Schinortriterpenoids with Identical Configuration but Distinct ECD Spectra Generated by Nondegenerate Exciton Coupling, Yiming Shi, 2018
  • Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus, Yiming Shi, 2018
  • Refining the Natural Product Repertoire in Entomopathogenic Bacteria, Yiming Shi, 2018
  • Lanostane-type triterpenoids from Kadsura coccinea, Yiming Shi, 2017
  • Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Go66, Yiming Shi, 2017
  • MICROROBIOLOGY A new language for small talk, Yiming Shi, 2017
  • Natural product diversity associated with the nematode symbionts Photorhabdus and Xenorhabdus, Yiming Shi, 2017
  • Structural Characterization of Kadcoccinin A: A Sesquiterpenoid with a Tricyclo4.4.0.0(3,10)decane Scaffold from Kadsura coccinea, Yiming Shi, 2016
  • Plasiatine, an Unprecedented Indole-Phenylpropanoid Hybrid from Plantago asiatica as a Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2, Yiming Shi, 2016
  • LC-UV-Guided Isolation and Structure Determination of Lancolide E: A Nortriterpenoid with a Tetracyclo5.4.0.0(2,4).0(3,7)undecane-Bridged System from a 'Talented' Schisandra Plant, Yiming Shi, 2016
  • Rearranged 6/6/5/6-Fused Triterpenoid Acids from the Stems of Kadsura coccinea, Yiming Shi, 2016
  • Chemical constituents from Piper wallichii, Yiming Shi, 2015
  • Kadcoccinones A-F, New Biogenetically Related Lanostane-Type Triterpenoids with Diverse Skeletons from Kadsura coccinea, Yiming Shi, 2015
  • Laxiflorol A, the first example of 7,8:15,16-di-seco-15-nor-21-homo-ent-kauranoid from Isodon eriocalyx var. laxiflora, Yiming Shi, 2015
  • Triterpenoids from the Schisandraceae family: an update, Yiming Shi, 2015
  • Lignans and aromatic glycosides from Piper wallichii and their antithrombotic activities, Yiming Shi, 2015
  • Two New 18-Norschiartane-type Schinortriterpenoids from Schisandra lancifolia, Yiming Shi, 2015
  • Kadcoccinic Acids A-J, Triterpene Acids from Kadsura coccinea, Yiming Shi, 2015
  • Structure and bioactivity of triterpenoids from the stems of Schisandra sphenanthera, Yiming Shi, 2014
  • Three new diterpenoids from Leonurus japonicus, Yiming Shi, 2014
  • Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia, Yiming Shi, 2014
  • Nortriterpenoids from Schisandra chinensis and their absolute configurational assignments by electronic circular dichroism study, Yiming Shi, 2014
  • New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities, Yiming Shi, 2014
  • Six new lignans from the leaves and stems of Schisandra sphenanthera, Yiming Shi, 2013
  • Bioactive phenolics and terpenoids from Manglietia insignis, Yiming Shi, 2013
  • Lancolides, Antiplatelet Aggregation Nortriterpenoids with Tricyclo6.3.0.0(2,11)undecane-Bridged System from Schisandra lancifolia, Yiming Shi, 2013
  • Four new lignans from the leaves and stems of Schisandra propinqua var. sinensis, Yiming Shi, 2013
  • Five New Nortriterpenoids from the Stems of Schisandra neglecta, Yiming Shi, 2013
  • Schisphenlignans A-E: Five New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera, Yiming Shi, 2013
  • Kadcotriones A-C: Tricyclic Triterpenoids from Kadsura coccinea, Yiming Shi, 2013
  • Asperterrestide A, a Cytotoxic Cyclic Tetrapeptide from the Marine-Derived Fungus Aspergillus terreus SCSGAF0162, Yiming Shi, 2013
  • Phenolic constituents from Parakmeria yunnanensis and their anti-HIV-1 activity, Yiming Shi, 2013
  • Schilancitrilactones A-C: Three Unique Nortriterpenoids from Schisandra lancifolia, Yiming Shi, 2012
  • Four new indole alkaloids from Plantago asiatica, Yiming Shi, 2012
  • Schilancitrilactones A-C: Three Unique Nortriterpenoids from Schisandra lancifolia, Yiming Shi, 2012
  • Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea, Yiming Shi, 2012
  • Ternifolide A, a New Diterpenoid Possessing a Rare Macrolide Motif from Isodon ternifolius, Yiming Shi, 2012
  • Schicagenins A-C: Three Cagelike Nortriterpenoids from Leaves and Stems of Schisandra chinensis, Yiming Shi, 2011
Awards
  • The Alexander von Humboldt Fellowship for Postdoctoral Research (2016): Other
  • The CAS Presidential Excellence Award (2014): Other
  • Outstanding Graduate Student Award at the CAS (2014): Other
  • First-Prize Di-Ao Award of the CAS (2013): Other
  • National Scholarship for Ph.D. Students (2013): National Level
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