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Shuangyan Tang
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English, Korean
Protein Engineering
Metabolic Engineering
Synthetic Biology
Biochemistry
Molecular Biology
Genetic Engineering
Biotechnology
Microbial Engineering
Enzyme Engineering
Cellular Engineering
Areas of Focus
- Protein Engineering
- Metabolic Engineering
- Synthetic Biology
Work Experience
- 2011-08~Present - Chinese Academy of Sciences, Institute of Microbiology - Researcher
- 2006-09~2010-12 - Pennsylvania State University - Postdoctoral Researcher
- 2003-03~2006-08 - Seoul National University, College of Agriculture and Life Sciences - Ph.D. Student
- 1998-07~2003-02 - Yunnan Institute for Drug Control - Chief Pharmacist
- 1995-09~1998-06 - Wuhan University, College of Life Sciences - Master's Student
- 1991-09~1995-06 - Wuhan University, College of Life Sciences - Bachelor's Student
Academic Background & Achievements
- 2003-03--2006-08 Ph.D.: Seoul National University, College of Agriculture and Life Sciences
- 1995-09--1998-06 Master's: Wuhan University, College of Life Sciences
- 1991-09--1995-06 Bachelor's: Wuhan University, College of Life Sciences
Publications
- Engineering and application of LacI mutants with stringent expressions, Shuangyan Tang, 2024
- Designing glucose utilization 'highway' for recombinant biosynthesis, Shuangyan Tang, 2023
- Engineering an SspB-mediated degron for novel controllable protein degradation, Shuangyan Tang, 2022
- Computational Redesign of a PETase for Plastic Biodegradation under Ambient Condition by the GRAPE Strategy, Shuangyan Tang, 2021
- Whole-Cell Biosensors Aid Exploration of Vanillin Transmembrane Transport, Shuangyan Tang, 2021
- De Novo Biosynthesis of Chlorogenic Acid Using an Artificial Microbial Community, Shuangyan Tang, 2021
- Dynamic control of toxic natural product biosynthesis by an artificial regulatory circuit, Shuangyan Tang, 2020
- Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps, Shuangyan Tang, 2020
- CRISPRi/dCpf1-mediated dynamic metabolic switch to enhance butenoic acid production in Escherichia coli, Shuangyan Tang, 2020
- Metabolic Engineering for Improved Curcumin Biosynthesis in Escherichia coli, Shuangyan Tang, 2020
- Development of a highly efficient and specific l-theanine synthase, Shuangyan Tang, 2020
- Engineering the effector specificity of regulatory proteins for the in vitro detection of biomarkers and pesticide residues, Shuangyan Tang, 2019
- Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis, Shuangyan Tang, 2019
- Towards the construction of high-quality mutagenesis libraries, Shuangyan Tang, 2018
- 人参果梗的化学成分研究, 唐双焱, 2018
- 2-O-α-D-吡喃葡萄糖基抗坏血酸研究进展, 唐双焱, 2017
- Design and application of a lactulose biosensor, Shuangyan Tang, 2017
- Biosensor-aided high-throughput screening of hyper-producing cells for malonyl-CoA-derived products, Shuangyan Tang, 2017
- Monitoring in vivo metabolic flux with a designed whole-cell metabolite biosensor of shikimic acid, Shuangyan Tang, 2017
- Improving key enzyme activity in phenylpropanoid pathway with a designed biosensor, Shuangyan Tang, 2017
- 碳水化合物结合结构域研究进展, 唐双焱, 2017
- Genetic biosensors for small-molecule products: Design and applications in high-throughput screening, Shuangyan Tang, 2017
- Research Progress on The Mechanism of Intramolecular Chaperone, Shuangyan Tang, 2016
- Putative Nonribosomal Peptide Synthetase and Cytochrome P450 Genes Responsible for Tentoxin Biosynthesis in Alternaria alternata ZJ33, Shuangyan Tang, 2016
- Directed evolution of leucine dehydrogenase for improved efficiency of l-tert-leucine synthesis, Shuangyan Tang, 2016
- Engineering a Carbohydrate-processing Transglycosidase into Glycosyltransferase for Natural Product Glycodiversification, Shuangyan Tang, 2016
- 人参茎叶总皂苷酶水解产物成分研究, 唐双焱, 2016
- Improving the thermoactivity and thermostability of pectate lyase from Bacillus pumilus for ramie degumming, Shuangyan Tang, 2015
- Design and Application of a Novel High-throughput Screening Technique for 1-Deoxynojirimycin, Shuangyan Tang, 2015
- Design of an ectoine-responsive AraC mutant and its application in metabolic engineering of ectoine biosynthesis, Shuangyan Tang, 2015
- Development of a novel uric-acid-responsive regulatory system in Escherichia coli, Shuangyan Tang, 2015
- 西洋参总皂苷酶水解产物成分研究, 唐双焱, 2014
- Screening for Enhanced Triacetic Acid Lactone Production by Recombinant Escherichia coli Expressing a Designed Triacetic Acid Lactone Reporter, Shuangyan Tang, 2013
- 高通量筛选工具的设计与应用, 唐双焱, 2012
- Design and Application of a Mevalonate-Responsive Regulatory Protein, Shuangyan Tang, 2011
- Elucidating residue roles in engineered variants of AraC regulatory protein, Shuangyan Tang, 2010
- AraC regulatory protein mutants with altered effector specificity, Shuangyan Tang, 2008
- Enhancing thermostability of maltogenic amylase from Bacillus thermoalkalophilus ET2 by DNA shuffling, Shuangyan Tang, 2006
- Contribution of W229 to the transglycosylation activity of 4-α-glucanotransferase from Pyrococcus furiosus, Shuangyan Tang, 2006
- Thermostable and alkalophilic maltogenic amylase of Bacillus thermoalkalophilus ET2 in monomer-dimer equilibrium, Shuangyan Tang, 2005
