Professor | Honglong Wu | Asia Growth Partners

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Name	Honglong Wu
Contact Information	wuhl@tib.cas.cn
Language ability	Chinese, English
Province	Tianjin

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Name

Honglong Wu

Contact Information

wuhl@tib.cas.cn

Language ability

Chinese, English

Province

Tianjin

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2013-09 to 2021-09 PhD: Huazhong University of Science and Technology 2008-09 to 2011-06 Master's: Shenzhen University 2004-09 to 2008-06 Bachelor's: Xinxiang Medical University
Work Experience	2018-08 to 2023-02 - Shenzhen BGI Inyuan Pharmaceutical Technology Co., Ltd. - CTO 2012-08 to 2018-08 - Tianjin BGI Medical Testing Laboratory Co., Ltd. - Head of Infection Direction 2008-07 to 2012-08 - Shenzhen BGI Research Institute - Bioinformatics Engineer
Awards	Beijing Science and Technology Award - Science and Technology Progress Award, Second Prize, Provincial Level, 2021

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2013-09 to 2021-09 PhD: Huazhong University of Science and Technology
2008-09 to 2011-06 Master's: Shenzhen University
2004-09 to 2008-06 Bachelor's: Xinxiang Medical University

Work Experience

2018-08 to 2023-02 - Shenzhen BGI Inyuan Pharmaceutical Technology Co., Ltd. - CTO
2012-08 to 2018-08 - Tianjin BGI Medical Testing Laboratory Co., Ltd. - Head of Infection Direction
2008-07 to 2012-08 - Shenzhen BGI Research Institute - Bioinformatics Engineer

Awards

Beijing Science and Technology Award - Science and Technology Progress Award, Second Prize, Provincial Level, 2021

Areas of Focus	Application of omics technology in the field of industrial biology
Publications	Evaluation of superinfection, antimicrobial usage, and airway microbiome with metagenomic sequencing in COVID-19 patients: A cohort study in Shanghai., Miao, Qing, Ma, Yuyan, Ling, Yun, Jin, Wenting, Su, Yi, Wang, Qingqing, Pan, Jue, Zhang, Yao, Chen, Hongyou, Yuan, Jianying, Wu, Honglong, Hu, Bijie., 2021 Improved cancer biomarkers identification using network-constrained infinite latent feature selection., Lihua Cai, Honglong Wu, Ke Zhou., 2021 Total infectomes of 162 SARS-CoV-2 cases using meta-transcriptomic sequencing., Zhou, Hong, Li, Cixiu, Hu, Tao, Liu, Ti, Ni, Nan, Chen, Weijun, Zhao, Huailong, Ruan, Shiman, Li, Juan, Wu, Honglong, Francois, Sarah, Pybus, Oliver G, Holmes, Edward C, Kang, Dianmin, Hou, Peiqiang, Shi, Weifeng., 2020 HCMB: A stable and efficient algorithm for processing the normalization of highly sparse Hi-C contact data., Wu, Honglong, Wang, Xuebin, Chu, Mengtian, Li, Dongfang, Cheng, Lixin, Zhou, Ke. FRMC: a fast and robust method for the imputation of scRNA-seq data., Wu, Honglong, Wang, Xuebin, Chu, Mengtian, Xiang, Ruizhi, Zhou, Ke. Rapid diagnosis of Talaromyces marneffei infection assisted by metagenomic next-generation sequencing in a HIV-negative patient., Zhang, Jingjia, Zhang, Dong, Du, Juan, Zhou, Yang, Cai, Yunting, Sun, Ruixue, Zhou, Jiali, Tian, Jingjing, Wu, Honglong, Lu, Minya, Xu, Yingchun, Yang, Qiwen. A rare case of adrenal gland abscess due to anaerobes detected by metagenomic next-generation sequencing., Jin, Wenting, Miao, Qing, Wang, Mengran, Zhang, Yao, Ma, Yuyan, Huang, Yingnan, Wu, Honglong, Lin, Yang, Hu, Bijie, Pan, Jue. Diagnostic value and clinical application of next-generation sequencing for infections in immunosuppressed patients with corticosteroid therapy., Wang, Sen, Ai, Jingwen, Cui, Peng, Zhu, Yimin, Wu, Honglong, Zhang, Wenhong., 2020 Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples., Xiao, Minfeng, Liu, Xiaoqing, Ji, Jingkai, Li, Min, Li, Jiandong, Yang, Lin, Sun, Wanying, Ren, Peidi, Yang, Guifang, Zhao, Jincun, Liang, Tianzhu, Ren, Huahui, Chen, Tian, Zhong, Huanzi, Song, Wenchen, Wang, Yanqun, Deng, Ziqing, Zhao, Yanping, Ou, Zhihua, Wang, Daxi, Cai, Jielun, Cheng, Xinyi, Feng, Taiqing, Wu, Honglong, Gong, Yanping, Yang, Huanming, Wang, Jian, Xu, Xun, Zhu, Shida, Chen, Fang, Zhang, Yanyan, Chen, Weijun, Li, Yimin, Li, Junhua., 2020 Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding., Lu, Roujian, Zhao, Xiang, Li, Juan, Niu, Peihua, Yang, Bo, Wu, Honglong, Wang, Wenling, Song, Hao, Huang, Baoying, Zhu, Na, Bi, Yuhai, Ma, Xuejun, Zhan, Faxian, Wang, Liang, Hu, Tao, Zhou, Hong, Hu, Zhenhong, Zhou, Weimin, Zhao, Li, Chen, Jing, Meng, Yao, Wang, Ji, Lin, Yang, Yuan, Jianying, Xie, Zhihao, Ma, Jinmin, Liu, William J, Wang, Dayan, Xu, Wenbo, Holmes, Edward C, Gao, George F, Wu, Guizhen, Chen, Weijun, Shi, Weifeng, Tan, Wenjie., 2020 Total Infectomes of 162 SARS-CoV-2 Cases Using Meta-Transcriptomic Sequencing., Hong Zhou, Cixiu Li, Tao Hu, Ti Liu, Nan Ni, Weijun Chen, Huailong Zhao, Shiman Ruan, Juan Li, Honglong Wu, Edward C Holmes, Dianmin Kang, Peiqiang Hou, Weifeng Shi., 2020 Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients., Xiong, Yong, Liu, Yuan, Cao, Liu, Wang, Dehe, Guo, Ming, Jiang, Ao, Guo, Dong, Hu, Wenjia, Yang, Jiayi, Tang, Zhidong, Wu, Honglong, Lin, Yongquan, Zhang, Meiyuan, Zhang, Qi, Shi, Mang, Liu, Yingle, Zhou, Yu, Lan, Ke, Chen, Yu., 2020 Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection., Zhang, Yi, Cui, Peng, Zhang, HaoCheng, Wu, HongLong, Ye, MingZhi, Zhu, YiMin, Ai, JingWen, Zhang, WenHong., 2020 Diagnostic accuracy of metagenomic next-generation sequencing for active tuberculosis in clinical practice at a tertiary general hospital., Jin, Wenting, Pan, Jue, Miao, Qing, Ma, Yuyan, Zhang, Yao, Huang, Yingnan, Yao, Yumeng, Su, Yi, Wang, Qingqing, Wang, Mengran, Li, Bing, Bao, Rong, Gao, Xiaodong, Wu, Honglong, Hu, Bijie., 2020 大规模检测平台在新型冠状病毒防控中的作用：基于新型数值模型的实证研究., 谢青, 王晶, 游简舲, 朱师达, 周锐, 田志坚, 吴昊, 林阳, 陈伟, 肖兰, 李建娟, 董杰, 吴红龙, 张伟, 李景, 牟峰, 徐讯, 尹烨, 陈唯军, 汪建. Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing., HongLong Wu, Yang Zhou, YiYi Qian, JiaLin Jin, Xian Zhou, JingWen Ai, Yue Ying, YiMin Zhu, Peng Cui, HongYu Wang, HaoCheng Zhang, WenHong Zhang., 2021 高通量测序技术诊疗幼儿急疹并热性惊厥1例., 徐佳佳, 吴红龙, 吴仁花., 2019 Detection of pathogens from resected heart valves of patients with infective endocarditis by next-generation sequencing., Cheng, Jun, Hu, Huan, Fang, Wei, Shi, Duozhi, Liang, Chen, Sun, Yang, Gao, GuoFeng, Wang, Hao, Zhang, Qian, Wang, LiQing, Wu, HongLong, Hu, Long, Chen, Luyao, Zhang, Jin, Lee, Shela, Wang, FeiYan, Zhou, Zhou., 2019 伪狂犬病毒脑炎临床观察与脑脊液二代测序鉴定., 赵伟丽, 乌依罕, 李红芳, 李世英, 范思远, 吴红龙, 李永军, 吕艳丽, 韩军, 张武超, 赵焱, 李国丽, 乔小东, 任海涛, 朱以诚, 彭斌, 崔丽英, 关鸿志. Metagenomics Biomarkers Selected for Prediction of Three Different Diseases in Chinese Population., Wu, Honglong, Cai, Lihua, Li, Dongfang, Wang, Xinying, Zhao, Shancen, Zou, Fuhao, Zhou, Ke., 2018 中枢神经系统李斯特菌感染患者的临床和脑脊液二代测序结果分析., 王晓娟, 关鸿志, 魏珂, 秦灵芝, 吴红龙, 李永军, 李玮., 2018 Use of next generation sequence to investigate potential novel macrolide resistance mechanisms in a population of Moraxella catarrhalis isolates., Liu, YaLi, Li, DongFang, Xu, HePing, Xiao, Meng, Cheng, JingWei, Zhang, Li, Xu, ZhiPeng, Chen, XinXin, Zhang, Ge, Kudinha, Timothy, Kong, Fanrong, Gong, YanPing, Wang, XinYing, Zhang, YinXin, Wu, HongLong, Xu, YingChun., 2016 新一代测序在中枢神经系统感染病原体检测中的应用., 吕遐, 关鸿志, 吴红龙, 朱以诚., 2016 De novo assembly of a haplotype-resolved human genome., Cao, Hongzhi, Wu, Honglong, Luo, Ruibang, Huang, Shujia, Sun, Yuhui, Tong, Xin, Xie, Yinlong, Liu, Binghang, Yang, Hailong, Zheng, Hancheng, Li, Jian, Li, Bo, Wang, Yu, Yang, Fang, Sun, Peng, Liu, Siyang, Gao, Peng, Huang, Haodong, Sun, Jing, Chen, Dan, He, Guangzhu, Huang, Weihua, Huang, Zheng, Li, Yue, Tellier, Laurent C A M, Liu, Xiao, Feng, Qiang, Xu, Xun, Zhang, Xiuqing, Bolund, Lars, Krogh, Anders, Kristiansen, Karsten, Drmanac, Radoje, Drmanac, Snezana, Nielsen, Rasmus, Li, Songgang, Wang, Jian, Yang, Huanming, Li, Yingrui, Wong, Gane KaShu., 2015 Type 2 Diabetes Biomarkers of Human Gut Microbiota Selected via Iterative Sure Independent Screening Method., Cai, Lihua, Wu, Honglong, Li, Dongfang, Zhou, Ke, Zou, Fuhao., 2015 An atlas of DNA methylomes in porcine adipose and muscle tissues., Li, Mingzhou, Wu, Honglong, Luo, Zonggang, Xia, Yudong, Guan, Jiuqiang, Wang, Tao, Gu, Yiren, Chen, Lei, Zhang, Kai, Ma, Jideng, Liu, Yingkai, Zhong, Zhijun, Nie, Jing, Zhou, Sh

Areas of Focus

Application of omics technology in the field of industrial biology

Publications

Evaluation of superinfection, antimicrobial usage, and airway microbiome with metagenomic sequencing in COVID-19 patients: A cohort study in Shanghai., Miao, Qing, Ma, Yuyan, Ling, Yun, Jin, Wenting, Su, Yi, Wang, Qingqing, Pan, Jue, Zhang, Yao, Chen, Hongyou, Yuan, Jianying, Wu, Honglong, Hu, Bijie., 2021
Improved cancer biomarkers identification using network-constrained infinite latent feature selection., Lihua Cai, Honglong Wu, Ke Zhou., 2021
Total infectomes of 162 SARS-CoV-2 cases using meta-transcriptomic sequencing., Zhou, Hong, Li, Cixiu, Hu, Tao, Liu, Ti, Ni, Nan, Chen, Weijun, Zhao, Huailong, Ruan, Shiman, Li, Juan, Wu, Honglong, Francois, Sarah, Pybus, Oliver G, Holmes, Edward C, Kang, Dianmin, Hou, Peiqiang, Shi, Weifeng., 2020
HCMB: A stable and efficient algorithm for processing the normalization of highly sparse Hi-C contact data., Wu, Honglong, Wang, Xuebin, Chu, Mengtian, Li, Dongfang, Cheng, Lixin, Zhou, Ke.
FRMC: a fast and robust method for the imputation of scRNA-seq data., Wu, Honglong, Wang, Xuebin, Chu, Mengtian, Xiang, Ruizhi, Zhou, Ke.
Rapid diagnosis of Talaromyces marneffei infection assisted by metagenomic next-generation sequencing in a HIV-negative patient., Zhang, Jingjia, Zhang, Dong, Du, Juan, Zhou, Yang, Cai, Yunting, Sun, Ruixue, Zhou, Jiali, Tian, Jingjing, Wu, Honglong, Lu, Minya, Xu, Yingchun, Yang, Qiwen.
A rare case of adrenal gland abscess due to anaerobes detected by metagenomic next-generation sequencing., Jin, Wenting, Miao, Qing, Wang, Mengran, Zhang, Yao, Ma, Yuyan, Huang, Yingnan, Wu, Honglong, Lin, Yang, Hu, Bijie, Pan, Jue.
Diagnostic value and clinical application of next-generation sequencing for infections in immunosuppressed patients with corticosteroid therapy., Wang, Sen, Ai, Jingwen, Cui, Peng, Zhu, Yimin, Wu, Honglong, Zhang, Wenhong., 2020
Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples., Xiao, Minfeng, Liu, Xiaoqing, Ji, Jingkai, Li, Min, Li, Jiandong, Yang, Lin, Sun, Wanying, Ren, Peidi, Yang, Guifang, Zhao, Jincun, Liang, Tianzhu, Ren, Huahui, Chen, Tian, Zhong, Huanzi, Song, Wenchen, Wang, Yanqun, Deng, Ziqing, Zhao, Yanping, Ou, Zhihua, Wang, Daxi, Cai, Jielun, Cheng, Xinyi, Feng, Taiqing, Wu, Honglong, Gong, Yanping, Yang, Huanming, Wang, Jian, Xu, Xun, Zhu, Shida, Chen, Fang, Zhang, Yanyan, Chen, Weijun, Li, Yimin, Li, Junhua., 2020
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding., Lu, Roujian, Zhao, Xiang, Li, Juan, Niu, Peihua, Yang, Bo, Wu, Honglong, Wang, Wenling, Song, Hao, Huang, Baoying, Zhu, Na, Bi, Yuhai, Ma, Xuejun, Zhan, Faxian, Wang, Liang, Hu, Tao, Zhou, Hong, Hu, Zhenhong, Zhou, Weimin, Zhao, Li, Chen, Jing, Meng, Yao, Wang, Ji, Lin, Yang, Yuan, Jianying, Xie, Zhihao, Ma, Jinmin, Liu, William J, Wang, Dayan, Xu, Wenbo, Holmes, Edward C, Gao, George F, Wu, Guizhen, Chen, Weijun, Shi, Weifeng, Tan, Wenjie., 2020
Total Infectomes of 162 SARS-CoV-2 Cases Using Meta-Transcriptomic Sequencing., Hong Zhou, Cixiu Li, Tao Hu, Ti Liu, Nan Ni, Weijun Chen, Huailong Zhao, Shiman Ruan, Juan Li, Honglong Wu, Edward C Holmes, Dianmin Kang, Peiqiang Hou, Weifeng Shi., 2020
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients., Xiong, Yong, Liu, Yuan, Cao, Liu, Wang, Dehe, Guo, Ming, Jiang, Ao, Guo, Dong, Hu, Wenjia, Yang, Jiayi, Tang, Zhidong, Wu, Honglong, Lin, Yongquan, Zhang, Meiyuan, Zhang, Qi, Shi, Mang, Liu, Yingle, Zhou, Yu, Lan, Ke, Chen, Yu., 2020
Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection., Zhang, Yi, Cui, Peng, Zhang, HaoCheng, Wu, HongLong, Ye, MingZhi, Zhu, YiMin, Ai, JingWen, Zhang, WenHong., 2020
Diagnostic accuracy of metagenomic next-generation sequencing for active tuberculosis in clinical practice at a tertiary general hospital., Jin, Wenting, Pan, Jue, Miao, Qing, Ma, Yuyan, Zhang, Yao, Huang, Yingnan, Yao, Yumeng, Su, Yi, Wang, Qingqing, Wang, Mengran, Li, Bing, Bao, Rong, Gao, Xiaodong, Wu, Honglong, Hu, Bijie., 2020
大规模检测平台在新型冠状病毒防控中的作用：基于新型数值模型的实证研究., 谢青, 王晶, 游简舲, 朱师达, 周锐, 田志坚, 吴昊, 林阳, 陈伟, 肖兰, 李建娟, 董杰, 吴红龙, 张伟, 李景, 牟峰, 徐讯, 尹烨, 陈唯军, 汪建.
Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing., HongLong Wu, Yang Zhou, YiYi Qian, JiaLin Jin, Xian Zhou, JingWen Ai, Yue Ying, YiMin Zhu, Peng Cui, HongYu Wang, HaoCheng Zhang, WenHong Zhang., 2021
高通量测序技术诊疗幼儿急疹并热性惊厥1例., 徐佳佳, 吴红龙, 吴仁花., 2019
Detection of pathogens from resected heart valves of patients with infective endocarditis by next-generation sequencing., Cheng, Jun, Hu, Huan, Fang, Wei, Shi, Duozhi, Liang, Chen, Sun, Yang, Gao, GuoFeng, Wang, Hao, Zhang, Qian, Wang, LiQing, Wu, HongLong, Hu, Long, Chen, Luyao, Zhang, Jin, Lee, Shela, Wang, FeiYan, Zhou, Zhou., 2019
伪狂犬病毒脑炎临床观察与脑脊液二代测序鉴定., 赵伟丽, 乌依罕, 李红芳, 李世英, 范思远, 吴红龙, 李永军, 吕艳丽, 韩军, 张武超, 赵焱, 李国丽, 乔小东, 任海涛, 朱以诚, 彭斌, 崔丽英, 关鸿志.
Metagenomics Biomarkers Selected for Prediction of Three Different Diseases in Chinese Population., Wu, Honglong, Cai, Lihua, Li, Dongfang, Wang, Xinying, Zhao, Shancen, Zou, Fuhao, Zhou, Ke., 2018
中枢神经系统李斯特菌感染患者的临床和脑脊液二代测序结果分析., 王晓娟, 关鸿志, 魏珂, 秦灵芝, 吴红龙, 李永军, 李玮., 2018
Use of next generation sequence to investigate potential novel macrolide resistance mechanisms in a population of Moraxella catarrhalis isolates., Liu, YaLi, Li, DongFang, Xu, HePing, Xiao, Meng, Cheng, JingWei, Zhang, Li, Xu, ZhiPeng, Chen, XinXin, Zhang, Ge, Kudinha, Timothy, Kong, Fanrong, Gong, YanPing, Wang, XinYing, Zhang, YinXin, Wu, HongLong, Xu, YingChun., 2016
新一代测序在中枢神经系统感染病原体检测中的应用., 吕遐, 关鸿志, 吴红龙, 朱以诚., 2016
De novo assembly of a haplotype-resolved human genome., Cao, Hongzhi, Wu, Honglong, Luo, Ruibang, Huang, Shujia, Sun, Yuhui, Tong, Xin, Xie, Yinlong, Liu, Binghang, Yang, Hailong, Zheng, Hancheng, Li, Jian, Li, Bo, Wang, Yu, Yang, Fang, Sun, Peng, Liu, Siyang, Gao, Peng, Huang, Haodong, Sun, Jing, Chen, Dan, He, Guangzhu, Huang, Weihua, Huang, Zheng, Li, Yue, Tellier, Laurent C A M, Liu, Xiao, Feng, Qiang, Xu, Xun, Zhang, Xiuqing, Bolund, Lars, Krogh, Anders, Kristiansen, Karsten, Drmanac, Radoje, Drmanac, Snezana, Nielsen, Rasmus, Li, Songgang, Wang, Jian, Yang, Huanming, Li, Yingrui, Wong, Gane KaShu., 2015
Type 2 Diabetes Biomarkers of Human Gut Microbiota Selected via Iterative Sure Independent Screening Method., Cai, Lihua, Wu, Honglong, Li, Dongfang, Zhou, Ke, Zou, Fuhao., 2015
An atlas of DNA methylomes in porcine adipose and muscle tissues., Li, Mingzhou, Wu, Honglong, Luo, Zonggang, Xia, Yudong, Guan, Jiuqiang, Wang, Tao, Gu, Yiren, Chen, Lei, Zhang, Kai, Ma, Jideng, Liu, Yingkai, Zhong, Zhijun, Nie, Jing, Zhou, Sh

Omics Industrial Biology Bioinformatics Genomics Metagenomics High-Throughput Sequencing Microbial Detection Pathogen Diagnosis Biotechnology Data Analysis

Qi Liu - Tongji University

Guifen Liu - Tongji University

Kailin Tang - Tongji University

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