1999-09--2002-06 PhD in Microbiology: Nankai University
1986-09--1989-06 MSc in Microbiology: Nankai University
1982-09--1986-06 BSc in Microbiology: Nankai University
2005-11~Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher, Doctoral Supervisor
2004-01~2005-09 - CNRS UPR9073, France - Postdoctoral Researcher
1989-08~2004-01 - First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine - Director of Molecular Biology Laboratory
Science and Technology Promotion Award, Chinese Academy of Sciences (2015): Key technologies and industrial applications for the modification of industrial production strains of lysine and threonine
Yinchuan City Industry-University-Research Cooperation Award (2016): Construction and optimization of fermentation conditions for L-threonine, L-serine, and L-methionine genetically engineered bacteria
Zhu Li Yuehua Excellent Teacher Award, Chinese Academy of Sciences (2015)
Excellent Graduate Student Supervisor Award, Chinese Academy of Sciences (2013)
Research
Biosynthesis and Metabolic Regulation of Important Biologics
Model-guided metabolic rewiring to bypass pyruvate oxidation for pyruvate derivative synthesis by minimising carbon loss, Yun Zhang, Xueliang Wang, Christianah Odesanmi, Qitiao Hu, Dandan Li, Yuan Tang, Zhe Liu, Jie Mi, Shuwen Liu, Tingyi Wen, 2024
Adaptive mechanisms of Bacillus to near space extreme environments, Aihua Deng, Tiantian Wang, Junyue Wang, Lai Li, Xueliang Wang, Li Liu, Tingyi Wen, 2023
A seamless and iterative DNA assembly method named PS-Brick and its assisted metabolic engineering for threonine and 1-propanol production, Shuwen Liu, Haihan Xiao, Fangfang Zhang, Zheng Lu, Yun Zhang, Aihua Deng, Zhongcai Li, Cui Yang, Tingyi Wen, 2019
Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli, Di Cui, Aihua Deng, Hua Bai, Zhao Yang, Yong Liang, Zhe Liub, Qidi Qiu, Laiyou Wang, Shuwen Liu, Yun Zhang, Yi Shi, Jianxun Qi, Tingyi Wen, 2019
Reconstruction of TCA cycle in Corynebacterium glutamicum with a genome-scale metabolic network model for trans-4-hydroxyproline production, Yu Zhang, Yun Zhang, Xiuling Shang, Bo Wang, Qitiao Hu, Shuwen Liu, Tingyi Wen, 2019
Pathogens in the Meibomian Gland and Conjunctival Sac: Microbiome of Normal Subjects and Patients with Meibomian Gland Dysfunction, Xiaodan Jiang, Aihua Deng, Jiarui Yang, Hua Bai, Zhao Yang, Jie Wu, Huibin Lv, Xuemin Li, Tingyi Wen, 2018
A RecET-assisted CRISPR-Cas9 genome editing in Corynebacterium glutamicum, Bo Wang, Qitiao Hu, Yu Zhang, Ruilin Shi, Xin Chai, Zhe Liu, Xiuling Shang, Yun Zhang, Tingyi Wen, 2018
Bacterial Genome Editing via a Designed Toxin−Antitoxin Cassette, Jie Wu, Aihua Deng, Qinyun Sun, Hua Bai, Zhaopeng Sun, Xiuling Shang, Yun Zhang, Qian Liu, Yong Liang, Shuwen Liu, Yongsheng Che, Tingyi Wen, 2018
Reprogramming one-carbon metabolic pathways to decouple l-serine catabolism from cell growth in Corynebacterium glutamicum, Yun Zhang, Xiuling Shang, Shujuan Lai, Yu Zhang, Qitiao Hu, Xin Chai, Bo Wang, Shuwen Liu, Tingyi Wen, 2018
Native promoters of Corynebacterium glutamicum and its application in l-lysine production, Xiuling Shang, Xin Chai, Xuemei Lu, Yuan Li, Yun Zhang, Guoqiang Wang, Chen Zhang, Shuwen Liu, Yu Zhang, Jiyin Ma, Tingyi Wen, 2018
A Novel Tool for Microbial Genome Editing Using the Restriction-Modification System, Hua Bai, Aihua Deng, Shuwen Liu, Di Cui, Qidi Qiu, Laiyou Wang, Zhao Yang, Jie Wu, Xiuling Shang, Yun Zhang, Tingyi Wen, 2018
The KMT1A-GATA3-STAT3 circuit is a novel self-renewal signaling of human bladder cancer stem cells, Zhao Yang, Luyun He, Kaisu Lin, Yun Zhang, Aihua Deng, Yong Liang, Chong Li, Tingyi Wen, 2017
A new genome-scale metabolic model of Corynebacterium glutamicum and its application, Yu Zhang, Jingyi Cai, Xiuling Shang, Bo Wang, Shuwen Liu, Xin Chai, Tianwei Tan, Yun Zhang, Tingyi Wen, 2017
A novel pyruvate kinase and its application in lactic acid production under oxygen deprivation in Corynebacterium glutamicum, Xin Chai, Xiuling Shang, Yu Zhang, Shuwen Liu, Yong Liang, Yun Zhang, Tingyi Wen, 2016
In vitro assembly of the bacterial actin protein MamK from ‘Candidatus Magnetobacterium casensis’ in the phylum Nitrospirae, Aihua Deng, Wei Lin, Nana Shi, Jie Wu, Zhaopeng Sun, Qinyun Sun, Hua Bai, Yongxin Pan, Tingyi Wen, 2016
YjeH Is a Novel Exporter of l-Methionine and Branched-Chain Amino Acids in Escherichia coli, Qian Liu, Yong Liang, Yun Zhang, Xiuling Shang, Shuwen Liu, Jifu Wen, Tingyi Wen, 2015
A high efficiency recombineering system with PCR-based ssDNA in Bacillus subtilis mediated by the native phage recombinase GP35, Zhaopeng Sun, Aihua Deng, Ting Hu, Jie Wu, Qinyun Sun, Hua Bai, Guoqiang Zhang, Tingyi Wen, 2015
Secretory expression, functional characterization and molecular genetic analysis of a novel halo-solvent-tolerant protease from Bacillus gibsonii, Aihua Deng, Guoqiang Zhang, Nana Shi, Jie Wu, Fuping Lu, Tingyi Wen, 2014
Characterization and Molecular Mechanism of AroP as an Aromatic Amino Acid and Histidine Transporter in Corynebacterium glutamicum, Xiuling Shang, Yun Zhang, Guoqiang Zhang, Xin Chai, Aihua Deng, Yong Liang, Tingyi Wen, 2013
Development of a two-stage feeding strategy based on the kind and level of feeding nutrients
