Areas of Focus
- Exploring underlying principles and rational design principles of cross-scale life systems using big data, AI, and mathematical models
- Genetic determinants and ecological rules of antibiotic resistance gene transmission
- Long-term evolution of prokaryotic life systems
Work Experience
- 2023-02 to Present - Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2015-07 to 2017-08 - Peking University, Center for Quantitative Biology - Research Assistant
Academic Background & Achievements
- 2017-08 to 2022-12 PhD in Biomedical Engineering: Duke University
- 2011-09 to 2015-07 Bachelor's in Biological Sciences: Peking University
Publications
- Horizontal gene transfer is predicted to overcome the diversity limit of competing microbial species, Corresponding Author, 2024
- A generic approach to infer community-level fitness of microbial genes, First Author, 2024
- Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria, Third Author, 2024
- Mapping single-cell responses to population-level dynamics during antibiotic treatment, Second Author, 2023
- Promotion of plasmid maintenance by heterogeneous partitioning of microbial communities, Second Author, 2023
- Intra- and interpopulation transposition of mobile genetic elements driven by antibiotic selection, Fifth Author, 2022
- Bringing cells to the edge, First Author, 2022
- Horizontal gene transfer enables programmable gene stability in synthetic microbiota, First Author, 2022
- Predicting plasmid persistence in microbial communities by coarse-grained modeling, First Author, 2021
- The persistence potential of transferable plasmids, First Author, 2020