Professor | Guoliang Xu | Asia Growth Partners

Upload Avatar (500 x 500)

Name

Guoliang Xu

Contact Information

glxu@sibs.ac.cn

Language ability

Chinese, German, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	1989-09--1993-03 PhD: Max Planck Institute for Molecular Genetics 1985-09--1988-08 Master's: Institute of Genetics, Chinese Academy of Sciences, Beijing 1981-09--1985-06 Bachelor's: Zhejiang University (formerly Hangzhou University)
Work Experience	2001-08~Present - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Researcher, Group Leader 2000-04~2001-07 - Columbia University Medical Center - Associate Research Scientist 1995-10~2000-03 - Department of Genetics and Development, Columbia University - Postdoctoral Researcher 1994-08~1995-09 - National University of Singapore, Life Sciences Center - Laboratory Director 1993-03~1994-07 - Max Planck Institute for Molecular Genetics - Postdoctoral Researcher
Awards	Third National Innovation Award (2023): National Level Shanghai Natural Science Award, First Prize (2016): Provincial Level 14th Shanghai Science and Technology Elite (2015): Provincial Level Chen Jiageng Life Science Award (2014): Other TWAS Biology Award (2013): Other

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

1989-09--1993-03 PhD: Max Planck Institute for Molecular Genetics
1985-09--1988-08 Master's: Institute of Genetics, Chinese Academy of Sciences, Beijing
1981-09--1985-06 Bachelor's: Zhejiang University (formerly Hangzhou University)

Work Experience

2001-08~Present - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Researcher, Group Leader
2000-04~2001-07 - Columbia University Medical Center - Associate Research Scientist
1995-10~2000-03 - Department of Genetics and Development, Columbia University - Postdoctoral Researcher
1994-08~1995-09 - National University of Singapore, Life Sciences Center - Laboratory Director
1993-03~1994-07 - Max Planck Institute for Molecular Genetics - Postdoctoral Researcher

Awards

Areas of Focus	Epigenetic regulation and its relationship with major diseases such as cancer
Publications	Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development, 11th Author, 2022 Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency, 11th Author, 2022 A vitamin-C-derived DNA modification catalysed by an algal TET homologue, 11th Author, 2019 TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling, 11th Author, 2016 Gadd45a promotes DNA demethylation through TDG, 11th Author, 2015 Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote, 11th Author, 2014 Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming, 11th Author, 2014 Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition, 1st Author, 2013 Vitamin C modulates TET1 function during somatic cell reprogramming, 1st Author, 2013 Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells, 1st Author, 2012 Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA, 11th Author, 2011 The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes, 11th Author, 2011

Areas of Focus

Epigenetic regulation and its relationship with major diseases such as cancer

Publications

Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development, 11th Author, 2022
Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency, 11th Author, 2022
A vitamin-C-derived DNA modification catalysed by an algal TET homologue, 11th Author, 2019
TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling, 11th Author, 2016
Gadd45a promotes DNA demethylation through TDG, 11th Author, 2015
Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote, 11th Author, 2014
Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming, 11th Author, 2014
Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition, 1st Author, 2013
Vitamin C modulates TET1 function during somatic cell reprogramming, 1st Author, 2013
Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells, 1st Author, 2012
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA, 11th Author, 2011
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes, 11th Author, 2011

Epigenetics Cancer Regulation Dna Methylation Gene Expression Chromatin Histones Non-Coding Rna Cell Differentiation Disease Mechanisms

Jiang Cizhong - Tongji University

Jiuhong Kang - Tongji University

Lu Dongdong - Tongji University

View All

Personal Information