Professor | Chun Xu | Asia Growth Partners

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Name	Chun Xu
Contact Information	chun.xu@ion.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Chun Xu

Contact Information

chun.xu@ion.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2003-09 to 2009-03 PhD in Science: Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 1999-09 to 2003-07 Bachelor of Science: Xiamen University
Work Experience	2017-01 to Present - Institute of Neuroscience, Chinese Academy of Sciences - Researcher 2009-05 to 2016-12 - FMI Research Institute, Basel, Switzerland - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2003-09 to 2009-03 PhD in Science: Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
1999-09 to 2003-07 Bachelor of Science: Xiamen University

Work Experience

2017-01 to Present - Institute of Neuroscience, Chinese Academy of Sciences - Researcher
2009-05 to 2016-12 - FMI Research Institute, Basel, Switzerland - Postdoctoral Researcher

Areas of Focus	Neurobiological mechanisms of context regulation of behavior Synaptic inputs and outputs of hippocampal cell subtypes Role of contextual regulation in anxiety and depression Role of contextual regulation in higher cognitive functions
Publications	An intein-split transactivator for intersectional neural imaging and optogenetic manipulation, Chen, HaoShan, Zhang, XiaoLong, Yang, RongRong, Wang, GuangLing, Zhu, XinYue, Xu, YuanFang, Wang, DanYang, Zhang, Na, Qiu, Shou, Zhan, LiJie, Shen, ZhiMing, Xu, XiaoHong, Long, Gang, Xu, Chun, 2022 Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies, Wang, Yuting, Dai, Guangyi, Gu, Zhili, Liu, Guopeng, Tang, Ke, Pan, YiHsuan, Chen, Yujie, Lin, Xin, Wu, Nan, Chen, Haoshan, Feng, Su, Qiu, Shou, Sun, Hongduo, Li, Qian, Xu, Chuan, Mao, Yanan, Zhang, Yong Edward, Khaitovich, Philipp, Wang, YanLing, Liu, Qunxiu, Han, JingDong Jackie, Shao, Zhen, Wei, Gang, Xu, Chun, Jing, Naihe, Li, Haipeng, 2020 Specific Hypothalamic Neurons Required for Sensing Conspecific Male Cues Relevant to Inter-male Aggression, Chen, AiXiao, Yan, JingJing, Zhang, Wen, Wang, Lei, Yu, ZiXian, Ding, XiaoJing, Wang, DanYang, Zhang, Min, Zhang, YanLi, Song, Nan, Jiao, ZhuoLei, Xu, Chun, Zhu, ShuJia, Xu, XiaoHong, 2020 VMHvl-Projecting Vglut1+ Neurons in the Posterior Amygdala Gate Territorial Aggression, Zha, Xi, Wang, Lei, Jiao, ZhuoLei, Yang, RongRong, Xu, Chun, Xu, XiaoHong, 2020 The orbitofrontal cortex projects to the parvafox nucleus of the ventrolateral hypothalamus and to its targets in the ventromedial periaqueductal grey matter, Babalian, Alexandre, Eichenberger, Simone, Bilella, Alessandro, Girard, Franck, Szabolcsi, Viktoria, Roccaro, Diana, AlvarezBolado, Gonzalo, Xu, Chun, Celio, Marco R., 2019 Adaptive disinhibitory gating by VIP interneurons permits associative learning, Krabbe, Sabine, Paradiso, Enrica, DAquin, Simon, Bitterman, Yael, Courtin, Julien, Xu, Chun, Yonehara, Keisuke, Markovic, Milica, Mueller, Christian, Eichlisberger, Tobias, Grundemann, Jan, Ferraguti, Francesco, Luthi, Andreas, 2019 NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis, Glangetas, Christelle, Massi, Lema, Fois, Giulia R, Jalabert, Marion, Girard, Delphine, Diana, Marco, Yonehara, Keisuke, Roska, Botond, Xu, Chun, Luthi, Andreas, Caille, Stephanie, Georges, Francois, 2017 A competitive inhibitory circuit for selection of active and passive fear responses, Fadok, Jonathan P, Krabbe, Sabine, Markovic, Milica, Courtin, Julien, Xu, Chun, Massi, Lema, Botta, Paolo, Bylund, Kristine, Mueller, Christian, Kovacevic, Aleksandar, Tovote, Philip, Luthi, Andreas, 2017 Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval, Xu, Chun, Krabbe, Sabine, Grundemann, Jan, Botta, Paolo, Fadok, Jonathan P, Osakada, Fumitaka, Saur, Dieter, Grewe, Benjamin F, Schnitzer, Mark J, Callaway, Edward M, Luthi, Andreas, 2016 Regulating anxiety with extrasynaptic inhibition, Botta, Paolo, Demmou, Lynda, Kasugai, Yu, Markovic, Milica, Xu, Chun, Fadok, Jonathan P, Lu, Tingjia, Poe, Michael M, Xu, Li, Cook, James M, Rudolph, Uwe, Sah, Pankaj, Ferraguti, Francesco, Luethi, Andreas, 2015 Tonic GABA(A) conductance decreases membrane time constant and increases EPSP-spike precision in hippocampal pyramidal neurons, Wlodarczyk, Agnieszka I, Xu, Chun, Song, Inseon, Doronin, Maxim, Wu, YuWei, Walker, Matthew C, Semyanov, Alexey, 2013 Identification and functional analysis of novel mutations of the CLCNKB gene in Chinese patients with classic Bartter syndrome, Yu, Y, Xu, C, Pan, X, Ren, H, Wang, W, Meng, X, Huang, F, Chen, N, 2010 GABAB receptor activation mediates frequency-dependent plasticity of developing hippocampal GABAergic synapses, Xu Chun, 2008

Areas of Focus

Neurobiological mechanisms of context regulation of behavior
Synaptic inputs and outputs of hippocampal cell subtypes
Role of contextual regulation in anxiety and depression
Role of contextual regulation in higher cognitive functions

Publications

An intein-split transactivator for intersectional neural imaging and optogenetic manipulation, Chen, HaoShan, Zhang, XiaoLong, Yang, RongRong, Wang, GuangLing, Zhu, XinYue, Xu, YuanFang, Wang, DanYang, Zhang, Na, Qiu, Shou, Zhan, LiJie, Shen, ZhiMing, Xu, XiaoHong, Long, Gang, Xu, Chun, 2022
Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies, Wang, Yuting, Dai, Guangyi, Gu, Zhili, Liu, Guopeng, Tang, Ke, Pan, YiHsuan, Chen, Yujie, Lin, Xin, Wu, Nan, Chen, Haoshan, Feng, Su, Qiu, Shou, Sun, Hongduo, Li, Qian, Xu, Chuan, Mao, Yanan, Zhang, Yong Edward, Khaitovich, Philipp, Wang, YanLing, Liu, Qunxiu, Han, JingDong Jackie, Shao, Zhen, Wei, Gang, Xu, Chun, Jing, Naihe, Li, Haipeng, 2020
Specific Hypothalamic Neurons Required for Sensing Conspecific Male Cues Relevant to Inter-male Aggression, Chen, AiXiao, Yan, JingJing, Zhang, Wen, Wang, Lei, Yu, ZiXian, Ding, XiaoJing, Wang, DanYang, Zhang, Min, Zhang, YanLi, Song, Nan, Jiao, ZhuoLei, Xu, Chun, Zhu, ShuJia, Xu, XiaoHong, 2020
VMHvl-Projecting Vglut1+ Neurons in the Posterior Amygdala Gate Territorial Aggression, Zha, Xi, Wang, Lei, Jiao, ZhuoLei, Yang, RongRong, Xu, Chun, Xu, XiaoHong, 2020
The orbitofrontal cortex projects to the parvafox nucleus of the ventrolateral hypothalamus and to its targets in the ventromedial periaqueductal grey matter, Babalian, Alexandre, Eichenberger, Simone, Bilella, Alessandro, Girard, Franck, Szabolcsi, Viktoria, Roccaro, Diana, AlvarezBolado, Gonzalo, Xu, Chun, Celio, Marco R., 2019
Adaptive disinhibitory gating by VIP interneurons permits associative learning, Krabbe, Sabine, Paradiso, Enrica, DAquin, Simon, Bitterman, Yael, Courtin, Julien, Xu, Chun, Yonehara, Keisuke, Markovic, Milica, Mueller, Christian, Eichlisberger, Tobias, Grundemann, Jan, Ferraguti, Francesco, Luthi, Andreas, 2019
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis, Glangetas, Christelle, Massi, Lema, Fois, Giulia R, Jalabert, Marion, Girard, Delphine, Diana, Marco, Yonehara, Keisuke, Roska, Botond, Xu, Chun, Luthi, Andreas, Caille, Stephanie, Georges, Francois, 2017
A competitive inhibitory circuit for selection of active and passive fear responses, Fadok, Jonathan P, Krabbe, Sabine, Markovic, Milica, Courtin, Julien, Xu, Chun, Massi, Lema, Botta, Paolo, Bylund, Kristine, Mueller, Christian, Kovacevic, Aleksandar, Tovote, Philip, Luthi, Andreas, 2017
Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval, Xu, Chun, Krabbe, Sabine, Grundemann, Jan, Botta, Paolo, Fadok, Jonathan P, Osakada, Fumitaka, Saur, Dieter, Grewe, Benjamin F, Schnitzer, Mark J, Callaway, Edward M, Luthi, Andreas, 2016
Regulating anxiety with extrasynaptic inhibition, Botta, Paolo, Demmou, Lynda, Kasugai, Yu, Markovic, Milica, Xu, Chun, Fadok, Jonathan P, Lu, Tingjia, Poe, Michael M, Xu, Li, Cook, James M, Rudolph, Uwe, Sah, Pankaj, Ferraguti, Francesco, Luethi, Andreas, 2015
Tonic GABA(A) conductance decreases membrane time constant and increases EPSP-spike precision in hippocampal pyramidal neurons, Wlodarczyk, Agnieszka I, Xu, Chun, Song, Inseon, Doronin, Maxim, Wu, YuWei, Walker, Matthew C, Semyanov, Alexey, 2013
Identification and functional analysis of novel mutations of the CLCNKB gene in Chinese patients with classic Bartter syndrome, Yu, Y, Xu, C, Pan, X, Ren, H, Wang, W, Meng, X, Huang, F, Chen, N, 2010
GABAB receptor activation mediates frequency-dependent plasticity of developing hippocampal GABAergic synapses, Xu Chun, 2008

Context Behavior Neurobiology Hippocampus Synaptic Inputs Outputs Anxiety Depression Cognition

Lin Longnian - East China Normal University

Shuwei Hao - Peking University

Lin Longnian - East China Normal University

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