Professor | Xiao Xiao | Asia Growth Partners

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Name	Xiao Xiao
Contact Information	xiaoxiao2@mail.kiz.ac.cn
Language ability	English, Chinese
Province	Yunnan

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Name

Xiao Xiao

Contact Information

xiaoxiao2@mail.kiz.ac.cn

Language ability

English, Chinese

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2011-08--2016-08 Ph.D.: Johns Hopkins University 2010-08--2011-05 Master of Public Health: Johns Hopkins University 2005-09--2009-06 Bachelor of Science: Wuhan University
Work Experience	2022-10~Present - Chinese Academy of Sciences Kunming Institute of Zoology - Researcher 2020-04~2022-10 - Chinese Academy of Sciences Kunming Institute of Zoology - Associate Researcher 2016-10~2020-04 - Chinese Academy of Sciences Kunming Institute of Zoology - Assistant Researcher 2011-08~2016-08 - Johns Hopkins University - Ph.D. 2010-08~2011-05 - Johns Hopkins University - Master of Public Health 2005-09~2009-06 - Wuhan University - Bachelor of Science

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2011-08--2016-08 Ph.D.: Johns Hopkins University
2010-08--2011-05 Master of Public Health: Johns Hopkins University
2005-09--2009-06 Bachelor of Science: Wuhan University

Work Experience

2022-10~Present - Chinese Academy of Sciences Kunming Institute of Zoology - Researcher
2020-04~2022-10 - Chinese Academy of Sciences Kunming Institute of Zoology - Associate Researcher
2016-10~2020-04 - Chinese Academy of Sciences Kunming Institute of Zoology - Assistant Researcher
2011-08~2016-08 - Johns Hopkins University - Ph.D.
2010-08~2011-05 - Johns Hopkins University - Master of Public Health
2005-09~2009-06 - Wuhan University - Bachelor of Science

Areas of Focus	Biological mechanisms of cognitive and other social behavior phenotypes
Publications	An alternative splicing hypothesis for neuropathology of schizophrenia: evidence from studies on historical candidate genes and multi-omics data, 2nd Author, 2022 A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, 4th Author, 2021 Translational genomics and beyond in bipolar disorder, Not mentioned, 2021 Integrative Analyses Followed by Functional Characterization Reveal TMEM180 as a Schizophrenia Risk Gene, 7th Author, 2021 Whole genome analyses reveal significant convergence in obsessive-compulsive disorder between humans and dogs, 8th Author, 2021 Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, 11th Author, 2021 Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, 4th Author, 2021 Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals A Genome-Wide Association Study and Meta-analysis, 47th Author, 2021 Further confirmation of netrin 1 receptor ( DCC ) as a depression risk gene via integrations of multi-omics data, 11th Author, 2020 Identification of a functional 339 bp Alu insertion polymorphism in the schizophrenia-associated locus at 10q24.32, 13th Author, 2020 Identification of a functional human-unique 351-bp Alu insertion polymorphism associated with major depressive disorder in the 1p31.1 GWAS risk loci, 11th Author, 2020 The genome-wide risk alleles for psychiatric disorders at 3p21.1 show convergent effects on mRNA expression, cognitive function, and mushroom dendritic spine, 11th Author, 2020 Genome-wide Association Study of Creativity Reveals Genetic Overlap With Psychiatric Disorders, Risk Tolerance, and Risky Behaviors, 8th Author, 2020 The depression GWAS risk allele predicts smaller cerebellar gray matter volume and reduced SIRT1 mRNA expression in Chinese population, 11th Author, 2019 Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, 11th Author, 2019 Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, 18th Author, 2019 Genetic insights and neurobiological implications from NRXN1 in neuropsychiatric disorders, 2nd Author, 2019 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study., 16th Author, 2018 The cAMP responsive element-binding (CREB)-1 gene increases risk of major psychiatric disorders, Not mentioned, 2018 The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, Not mentioned, 2018 Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, 11th Author, 2018 The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder, 1st Author, 2018 Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations, 7th Author, 2018 The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, Not mentioned, 2017 Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, 11th Author, 2017 Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders, 1st Author, 2017 Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population, 3rd Author, 2013 Genetic association and identification of a functional SNP at GSK3 beta for schizophrenia susceptibility, 4th Author, 2011

Areas of Focus

Biological mechanisms of cognitive and other social behavior phenotypes

Publications

An alternative splicing hypothesis for neuropathology of schizophrenia: evidence from studies on historical candidate genes and multi-omics data, 2nd Author, 2022
A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, 4th Author, 2021
Translational genomics and beyond in bipolar disorder, Not mentioned, 2021
Integrative Analyses Followed by Functional Characterization Reveal TMEM180 as a Schizophrenia Risk Gene, 7th Author, 2021
Whole genome analyses reveal significant convergence in obsessive-compulsive disorder between humans and dogs, 8th Author, 2021
Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, 11th Author, 2021
Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, 4th Author, 2021
Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals A Genome-Wide Association Study and Meta-analysis, 47th Author, 2021
Further confirmation of netrin 1 receptor ( DCC ) as a depression risk gene via integrations of multi-omics data, 11th Author, 2020
Identification of a functional 339 bp Alu insertion polymorphism in the schizophrenia-associated locus at 10q24.32, 13th Author, 2020
Identification of a functional human-unique 351-bp Alu insertion polymorphism associated with major depressive disorder in the 1p31.1 GWAS risk loci, 11th Author, 2020
The genome-wide risk alleles for psychiatric disorders at 3p21.1 show convergent effects on mRNA expression, cognitive function, and mushroom dendritic spine, 11th Author, 2020
Genome-wide Association Study of Creativity Reveals Genetic Overlap With Psychiatric Disorders, Risk Tolerance, and Risky Behaviors, 8th Author, 2020
The depression GWAS risk allele predicts smaller cerebellar gray matter volume and reduced SIRT1 mRNA expression in Chinese population, 11th Author, 2019
Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, 11th Author, 2019
Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, 18th Author, 2019
Genetic insights and neurobiological implications from NRXN1 in neuropsychiatric disorders, 2nd Author, 2019
Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study., 16th Author, 2018
The cAMP responsive element-binding (CREB)-1 gene increases risk of major psychiatric disorders, Not mentioned, 2018
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, Not mentioned, 2018
Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, 11th Author, 2018
The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder, 1st Author, 2018
Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations, 7th Author, 2018
The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, Not mentioned, 2017
Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, 11th Author, 2017
Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders, 1st Author, 2017
Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population, 3rd Author, 2013
Genetic association and identification of a functional SNP at GSK3 beta for schizophrenia susceptibility, 4th Author, 2011

Cognition Social Behavior Biological Mechanisms Phenotypes Genetics Neuroscience Psychiatry Behavioral Science Mental Health Research

Wen Chen - Tongji University

Wenzhe Li - Tongji University

Xiaoli Wang - Shanghai Normal University

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