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Jun Xu
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Insect
Organ
Development
Communication
Genetics
Molecular Biology
Physiology
Entomology
Research
Biology
Areas of Focus
- Insect Organ Development and Inter-organ Communication
Work Experience
- 2022-10~Present - Chinese Academy of Sciences, Center for Excellence in Molecular Plant Sciences - Researcher
- 2019-09~2022-10 - Harvard University - Postdoctoral Researcher
- 2017-07~2019-08 - Chinese Academy of Sciences, Center for Excellence in Molecular Plant Sciences - Postdoctoral Researcher
Academic Background & Achievements
- 2012-09--2017-06 PhD: University of Chinese Academy of Sciences
- 2008-09--2012-07 Bachelor's Degree: Guangxi University
Publications
- Mechanistic characterization of a Drosophila model of paraneoplastic nephrotic syndrome, Corresponding Author, 2024
- A phosphate-sensing organelle regulates phosphate and tissue homeostasis, Second Author, 2023
- split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80, Third Author, 2023
- Transcriptional and functional motifs defining renal function revealed by single nuclear sequencing, First Author, 2022
- Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies, Corresponding Author, 2022
- Mutation of Serine protease 1 Induces Male Sterility in Bombyx mori, Sixth Author, 2022
- NanoTag Nanobody Tools for Drosophila In Vitro and In Vivo Studies, Corresponding Author, 2022
- Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly, Not mentioned, 2022
- 5′-Nucleotidase Plays a Key Role in Uric Acid Metabolism of Bombyx mori, Seventh Author, 2021
- mTORC1-chaperonin CCT signaling regulates m(6)A RNA methylation to suppress autophagy, Other (Collaborative Group Author), 2021
- Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila, Third Author, 2021
- Mutation of P-element somatic inhibitor induces male sterility in the diamondback moth, Plutella xylostella, Sixth Author, 2021
- Genomic landscape and genetic manipulation of the black soldier fly Hermetia illucens,a natural waste recycler, Fifth Author, 2020
- Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade, First Author, 2020
- Disruption of the ovarian serine protease (Osp) gene causes female sterility in Bombyx mori and Spodoptera litura, Fifth Author, 2020
- Mutation of doublesex in Hyphantria cunea results in sex-specific sterility, Eighth Author, 2020
- Mutation of the seminal protease gene, serine protease 2, results in male sterility in diverse lepidopterans, Fourth Author, 2020
- Dysfunction of dimorphic sperm impairs male fertility in the silkworm, Corresponding Author, 2020
- MicroRNA-2738 regulates gene expression in the sex determination pathway in Bombyx mori, Corresponding Author, 2020
- Gtsf1 is essential for proper female sex determination and transposon silencing in the silkworm, Bombyx mori, Corresponding Author, 2020
- miR-34 regulates larval growth and wing morphogenesis by directly modulating ecdysone signalling and cuticle protein inBombyx mori, Second Author, 2020
- Identification of a germline-expression promoter for genome editing in Bombyx mori, First Author, 2019
- Intersex regulates female external genital and imaginal disc development in the silkworm, First Author, 2019
- Genome editing in insects: current status and challenges, First Author, 2019
- CRISPR Disruption of BmOvo Resulted in the Failure of Emergence and Affected the Wing and Gonad Development in the Silkworm Bombyx mori, Seventh Author, 2019
- The Masc gene product controls masculinization in the black cutworm, Agrotis ipsilon, Fourth Author, 2019
- Maelstrom regulates spermatogenesis of the silkworm, Bombyx mori, Third Author, 2019
- CRISPR/Cas9-mediated ebony knockout results in puparium melanism in Spodoptera litura, Second Author, 2019
- Mutation of doublesex induces sex-specific sterility of the diamondback moth Plutella xylostella, Fourth Author, 2019
- Mass spider silk production through targeted gene replacement in Bombyx mori, First Author, 2018
- CRISPR disruption of TCTP gene impaired normal development in the silkworm Bombyx mori, Second Author, 2018
- MicroRNA-14 regulates larval development time in Bombyx mori, Third Author, 2018
- The FOXO transcription factor controls insect growth and development by regulating juvenile hormone degradation in the silkworm, Bombyx mori, Third Author, 2017
- Transgenic Clustered Regularly Interspaced Short Palindromic Repeat/Cas9-Mediated Viral Gene Targeting for Antiviral Therapy of Bombyx mori Nucleopolyhedrovirus, Fifth Author, 2017
- Sexually dimorphic traits in the silkworm, Bombyx mori , are regulated by doublesex, First Author, 2017
- Bombyx mori P-element Somatic Inhibitor (BmPSI) Is a Key Auxiliary Factor for Silkworm Male Sex Determination, First Author, 2017
- CRISPR/Cas9-mediated targeted gene mutagenesis in Spodoptera litura, Second Author, 2016
- Expansion of CRISPR targeting sites in Bombyx mori, Fifth Author, 2016
- Functional characterization of SlitPBP3 in Spodoptera litura by CRISPR/Cas9 mediated genome editing, Second Author, 2016
- Transgenic characterization of two testis-specific promoters in the silkworm, Bombyx mori, Not mentioned, 2015
- MiR-2 family targets awd and fng to regulate wing morphogenesis in Bombyx mori, Fifth Author, 2015
- Ectopic expression of ecdysone oxidase impairs tissue degeneration in Bombyx mori, Fifth Author, 2015
- Enhancement of Larval RNAi Efficiency by Over-expressing Argonaute2 in Bombyx mori, Fourth Author, 2015
- Site-specific, TALENs-mediated transformation of Bombyx mori, Third Author, 2014
- CYP18A1 regulates tissue-specific steroid hormone inactivation in Bombyx mori, Fifth Author, 2014
- MicroRNA Let-7 regulates molting and metamorphosis in the silkworm, Bombyx mori, Fifth Author, 2014
- Transcription activator-like effector nuclease (TALEN)-mediated female-specific sterility in the silkworm, Bombyx mori, Not mentioned, 2014
- Functional characterization of the vitellogenin promoter in the silkworm, Bombyx mori, Not mentioned, 2014
- Allelic-specific expression in relation to Bombyx mori resistance to Bt toxin, Ninth Author, 2014
- Genetic Regulation of Insect Populations, Second Author, 2013
- In vitro culture system of stem segments from Cuscuta japonica, First Author, 2013
- The CRISPR/Cas System mediates efficient genome engineering in Bombyx mori, Third Author, 2013
- Effects of Three Plant Extracts on Growth and Development of Dodder and Soybean and on Protective Enzymes of Host, Second Author, 2012
- Physiological Response of Schefflera odorata cv.Variegata to Cuscuta japonica Parasitization, First Author, 2010
Awards
- Harvard Chinese Life Sciences Outstanding Research Award (2023): Other
- Postdoctoral Innovative Talent Support Program Excellent Innovation Achievement Award (2020): Other
- Sanofi-Shanghai Institute of Biological Sciences Outstanding Young Talent Award Fund (2018): Other
