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Dandan Yu
Life Science
University of Chinese Academy of Sciences
Yunnan
Language: Chinese, English
Virus
Infection
Animal Model
Antiviral
Innate Immunity
Research
Immunology
Pathogenesis
Genetics
Virology
Areas of Focus
- Virus Infection Animal Model Establishment and Antiviral Innate Immunity Research
Work Experience
- 2007-12~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
- 2005-07~2007-11 - Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences - Research Intern
- 2002-09~2005-06 - Nanjing Agricultural University - Master's Student
- 1998-09~2002-06 - Nanjing Agricultural University - Undergraduate Student
Academic Background & Achievements
- 2002-09--2005-06 Master's Degree: Nanjing Agricultural University
- 1998-09--2002-06 Bachelor's Degree: Nanjing Agricultural University
Publications
- SARS-CoV-2 Spike protein S2 subunit modulates gama-secretase and enhances amyloid-beta production in COVID-19 neuropathy, Dandan Yu, 2022
- Characterizing the role of Tupaia DNA damage inducible transcript 3 (DDIT3) gene in viral infections, Dandan Yu, 2022
- Characteristics of replication and pathogenicity of SARS-CoV-2 Alpha and Delta isolates, Dandan Yu, 2022
- Single-nucleus transcriptomic profiling of multiple organs in a rhesus macaque model of SARS-CoV-2 infection, Dandan Yu, 2022
- A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core, Dandan Yu, 2022
- Optimization of Milk Substitutes for the Artificial Rearing of Chinese Tree Shrews (Tupaia belangeri chinensis), Dandan Yu, 2022
- Infectivity of SARS-CoV-2 and protection against reinfection in rats, Dandan Yu, 2022
- SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target, Dandan Yu, 2021
- Tupaia guanylate-binding protein 1 interacts with vesicular stomatitis virus phosphoprotein and represses primary transcription of the viral genome, Dandan Yu, 2021
- Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study, Dandan Yu, 2021
- Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2, Dandan Yu, 2021
- Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS, Dandan Yu, 2020
- An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, Dandan Yu, 2020
- Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, Dandan Yu, 2020
- COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2, Dandan Yu, 2020
- Establishment and transcriptomic features of an immortalized hepatic cell line of the Chinese tree shrew, Dandan Yu, 2020
- Molecular characterization of the 2',5'-oligoadenylate synthetase family in the Chinese tree shrew (Tupaia belangeri chinensis), Dandan Yu, 2019
- Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis), Dandan Yu, 2019
- Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I, Dandan Yu, 2019
- Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis), Dandan Yu, 2019
- The 3 ' UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, Dandan Yu, 2019
- Identification and characterization of toll-like receptors (TLRs) in the Chinese tree shrew ( Tupaia belangeri chinensis ), Dandan Yu, 2016
- Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew, Dandan Yu, 2016
- Mitochondrial genome variations and functional characterization in Han Chinese families with schizophrenia, Dandan Yu, 2016
- Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis), Dandan Yu, 2015
- Molecular characterization, tissue distribution and expression analysis of TRIM25 in Gallus gallus domesticus, Dandan Yu, 2015
- Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens, Dandan Yu, 2014
- IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma, Dandan Yu, 2014
- Diverse Interleukin-7 mRNA Transcripts in Chinese Tree Shrew (Tupaia belangeri chinensis), Dandan Yu, 2014
- Is mitochondrial tRNA(phe) variant m.593T>C a synergistically pathogenic mutation in Chinese LHON families with m.11778G>A?, Dandan Yu, 2011
- Mitochondrial DNA Sequence Variation and Haplogroup Distribution in Chinese Patients with LHON and m.14484T > C, Dandan Yu, 2010
- Molecular characterization of six Chinese families with m.3460G > A and Leber hereditary optic neuropathy, Dandan Yu, 2010
- Reverse genetic manipulation of the overlapping coding regions for structural proteins of the type II porcine reproductive and respiratory syndrome virus, Dandan Yu, 2009
Awards
- Leber Hereditary Optic Neuropathy Genetic Susceptibility Research (2015): Second Prize, Provincial Level
