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Keqiong Ye
yekeqiong@ibp.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 1995-09--2000-12 PhD: Institute of Biophysics, Chinese Academy of Sciences
  • 1990-09--1995-06 Bachelor's: Zhejiang University
  • 2014-present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
  • 2011-2014 - Beijing Institute of Life Sciences - Senior Researcher
  • 2005-2011 - Beijing Institute of Life Sciences - Researcher
  • 2001-2005 - Memorial Sloan Kettering Cancer Center, USA - Postdoctoral Fellow
Eukaryotic Ribosome Assembly
H/ACA and C/D RNA-Protein Complexes
RNA Silencing
  • Dimerization mediated by a divergent FHA domain is essential for the DNA damage and spindle functions of fission yeast Mdb1, Shukun Luo, Xiaoran Xin, Li-Lin Du, Keqiong Ye, Yi Wei, 2015
  • Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complex, Xing Zhu, Keqiong Ye, 2015
  • Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation, Sanduo Zheng, Raffaella Villa, Jia Wang, Yingang Feng, Jinfeng Wang, Peter B. Becker, Keqiong Ye, 2014
  • Interaction of ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast, Sanduo Zheng, Pengfei Lan, Ximing Liu, Keqiong Ye, 2014
  • Purification, crystallization and preliminary X-ray diffraction analysis of Imp3 in complex with an Mpp10 peptide involved in yeast ribosome biogenesis, Sanduo Zheng, Keqiong Ye, 2014
  • CLIP techniques in studying protein-RNA interactions, Dejian Zhou, Keqiong Ye, 2014
  • Structure of Utp21 tandem WD domain provides insight into the organization of the UTPB complex involved in ribosome synthesis, Cheng Zhang, Jinzhong Lin, Weixiao Liu, Xining Chen, Rongchang Chen, Keqiong Ye, 2014
  • Structural and functional analysis of Utp23, a yeast ribosome synthesis factor with degenerate PIN domain, Jing Lu, Mengyi Sun, Keqiong Ye, 2013
  • An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme, Jinzhong Lin, Jing Lu, Yingang Feng, Mengyi Sun, Keqiong Ye, 2013
  • Single modification at position 14 of siRNA strand abolishes its gene-silencing activity by decreasing both RISC loading and target degradation, Jie Zheng, Lei Zhang, Junbin Zhang, Xiaoxia Wang, Keqiong Ye, Zhen Xi, Quan Du, Zicai Liang, 2013
  • Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant, Yue-He Ding, Yun-Guang Du, Shukun Luo, Yu-Xin Li, Tie-Mei Li, Sawako Yoshina, Xing Wang, Karsten Klage, Shohei Mitani, Keqiong Ye, Meng-Qiu Dong, 2013
  • Structural and functional analysis of the U3 snoRNA binding protein Rrp9, Liman Zhang, Jinzhong Lin, Keqiong Ye, 2013
  • Solution structure of MSL2 CXC domain reveals an unusual Zn3Cys9 cluster and similarity to pre-SET domains of histone lysine methyltransferases, Sanduo Zheng, Jia Wang, Yingang Feng, Jinfeng Wang, Keqiong Ye, 2012
  • Kinetic and thermodynamic characterization of the reaction pathway of box H/ACA RNA-guided pseudouridine formation, Xinxing Yang, Jinqi Duan, Shuang Li, Peng Wang, Shoucai Ma, Keqiong Ye, Xin Sheng Zhao, 2012
  • Identification of cross-linked peptides from complex samples, Bing Yang, Yan-Jie Wu, Ming Zhu, Sheng-Bo Fan, Jinzhong Lin, Kun Zhang, Shuang Li, Hao Chi, Yu-Xin Li, Hai-Feng Chen, Shu-Kun Luo, Yue-He Ding, Le-Heng Wang, Zhiqi Hao, Li-Yun Xiu, She Chen, Keqiong Ye, Si-Min He, Meng-Qiu Dong, 2012
  • Crystal structure of Cmr2 suggests a nucleotide cyclase-related enzyme in type III CRISPR-Cas systems, Xing Zhu, Keqiong Ye, 2012
  • Plant actin-binding protein SCAB1 is dimeric actin cross-linker with atypical pleckstrin homology domain, Wei Zhang, Yang Zhao, Yan Guo, Keqiong Ye, 2012
  • Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1, Shukun Luo, Keqiong Ye, 2012
  • Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain, Jinping Liu, Shukun Luo, Hongchang Zhao, Ji Liao, Jing Li, Chunying Yang, Bo Xu, David F. Stern, Xingzhi Xu, Keqiong Ye, 2012
  • Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita, Shuang Li, Jingqi Duan, Dandan Li, Shoucai Ma, Keqiong Ye, 2011
  • Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase, Shuang Li, Jingqi Duan, Dandan Li, Bing Yang, Mengqiu Dong, Keqiong Ye, 2011
  • Structure and molecular evolution of CDGSH iron-sulfur domains, Jinzhong Lin, Liman Zhang, Shaomei Lai, Keqiong Ye, 2011
  • The Plant-Specific Actin Binding Protein SCAB1 Stabilizes Actin Filaments and Regulates Stomatal Movement in Arabidopsis, Yang Zhao, Shuangshuang Zhao, Tonglin Mao, Xiaolu Qu, Wanhong Cao, Li Zhang, Wei Zhang, Liu He, Sidi Li, Sulin Ren, Jinfeng Zhao, Guoli Zhu, Shanjin Huang, Keqiong Ye, Ming Yuan, Yan Guo, 2011
  • Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase, Bihong Guo, Jinzhong Lin, Keqiong Ye, 2011
  • Structural basis of site-specific ribose methylation by box C/D RNA protein complexes, Jinzhong Lin, Shaomei Lai, Ru Jia, Anbi Xu, Liman Zhang, Jing Lu, Keqiong Ye, 2011
  • Crystal structure and centromere binding of the plasmid segregation protein ParB from pCXC100, Lin Huang, Ping Yin, Xing Zhu, Yi Zhang, Keqiong Ye, 2011
  • Progress in structural biology of RNA silencing, Wei Zhang, Keqiong Ye, 2010
  • Size-independent and non-cooperative recognition of dsRNA by the Rice stripe virus RNA silencing suppressor NS3, Mei Shen, Yi Xu, Ru Jia, Xueping Zhou, Keqiong Ye, 2010
  • Structural organization of box C/D RNA-guided RNA methyltransferase, Keqiong Ye, Ru Jia, Jinzhong Lin, Minghua Ju, Jin Peng, Anbi Xu, Liman Zhang, 2009
  • Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthase, Jingqi Duan, Ling Li, Jing Lu, Wei Wang, Keqiong Ye, 2009
  • H/ACA RNAs, proteins and complexes, Keqiong Ye, 2007
  • Crystal structure of human mitoNEET reveals distinct groups of iron-sulfur proteins, Jinzhong Lin, Tao Zhou, Keqiong Ye, Jinfeng Wang, 2007
  • Crystal structure of an H/ACA box ribonucleoprotein particle, Ling Li, Keqiong Ye, 2006
  • Structural Biology of RNA Silencing and Its Functional Implications, D.J. Patel, J.-B. Ma, Y.-R. Yuan, K. Ye, Y. Pei, V. Kuryavyi, L. Malinina, G. Meister, T. Tuschl, 2006
  • RNA silencing suppressor p21 of Beet Yellows Virus forms an RNA-binding octameric ring structure, K. Ye, D.J. Patel, 2005
  • Structural mechanism of overhang-specific small interfering RNA recognition of the PAZ domain, J. Ma, K. Ye, D.J. Patel, 2004
  • Recognition of small interfering RNA by a viral suppressor of RNA silencing, K. Ye, L. Malinina, D.J. Patel, 2003
  • NMR study of the conformational transition of cytochrome c upon the displacement of Met80 by exogenous ligand: structural and magnetic characterization of azidoferricytochrome c, Y. Yao, Y. Wu, C. Qian, K. Ye, J. Wang, W. Tang, 2003
  • Ribosome-associated factor Y adopts a fold resembling a double-stranded RNA binding domain scaffold, K. Ye, A. Serganov, W. Hu, M. Garber, D.J. Patel, 2002
  • Solution structure of cyanoferricytochrome c: ligand-controlled conformational flexibility and electronic structure of the heme moiety, Y. Yao, C. Qian, K. Ye, J. Wang, Z. Bai, W. Tang, 2002
  • Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c, C. Qian, Y. Yao, K. Ye, J. Wang, W. Tang, Y. Wang, W. Wang, J. Lu, Y. Xie, Z. Huang, 2001
  • Self-association reaction of denatured staphylococcal nuclease fragments characterized by heteronuclear NMR
Ribosome Rna Protein Translation Modification Gene Regulation X-Ray Crystallography Electron Microscopy Nmr Yeast Genetics

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