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Xiao Yu
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: English, Chinese
Emotion
Sleep
Stress
Instinctive Behavior
Neuroscience
Brain
Behavior
Neural Circuits
Mental Health
Cognitive Function
Areas of Focus
- Emotion
- Sleep
- Stress
- Instinctive Behavior
Work Experience
- 2023-03 to Present - Chinese Academy of Sciences, Center for Excellence in Brain Science and Intelligence Technology - Researcher
- 2021-11 to 2022-12 - King's College London - Senior Scientist
- 2019-09 to 2021-10 - Boston Children's Hospital, Harvard Medical School - Postdoctoral Fellow
- 2014-09 to 2019-09 - Imperial College London - Postdoctoral Fellow
- 2013-11 to 2014-09 - Imperial College London - Research Assistant
- 2010-10 to 2014-10 - Imperial College London - PhD
Academic Background & Achievements
- 2010-10 to 2014-10 PhD: Imperial College London
Publications
- Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus, 2nd Author, 2023
- Editorial: Behaviors and Neural Circuits in Sleep and Sedation, 11th Author, 2022
- A specific circuit in the midbrain detects stress and induces restorative sleep, 11th Author, 2022
- Nitric Oxide Synthase Neurons in the Preoptic Hypothalamus Are NREM and REM Sleep-Active and Lower Body Temperature, 4th Author, 2021
- Brain Clocks, Sleep, and Mood, 1st Author, 2021
- Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior, 11th Author, 2021
- Genetic lesioning of histamine neurons increases sleep-wake fragmentation and reveals their contribution to modafinil-induced wakefulness, 1st Author, 2019
- Galanin Neurons Unite Sleep Homeostasis and α2-Adrenergic Sedation, 3rd Author, 2019
- GABA and glutamate neurons in the VTA regulate sleep and wakefulness, 1st Author, 2019
- Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation, 6th Author, 2018
- A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus, 2nd Author, 2018
- Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems, 1st Author, 2018
- Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAA Receptors with Different α Subunits, 2nd Author, 2017
- Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus, 3rd Author, 2016
- Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons, 5th Author, 2016
- Wakefulness Is Governed by GABA and Histamine Cotransmission, 1st Author, 2015
- Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists, 8th Author, 2015
- The Constitutive Activation of Egr-1/C/EBPa Mediates the Development of Type 2 Diabetes Mellitus by Enhancing Hepatic Gluconeogenesis, 4th Author, 2015
- Circadian Factor BMAL1 in Histaminergic Neurons Regulates Sleep Architecture, 1st Author, 2014
- An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism, 2nd Author, 2011
- Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice, 1st Author, 2011
- Celastrol Attenuates Hypertension-Induced Inflammation and Oxidative Stress in Vascular Smooth Muscle Cells via Induction of Heme Oxygenase-1, 1st Author, 2010
- Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice, 3rd Author, 2010
- GABAergic Inhibition of Histaminergic Neurons Regulates Active Waking But Not the sleep-wake Switch or Propofol-Induced Loss of Consciousness, 2nd Author
