Professor | Xiao Yu | Asia Growth Partners

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Name	Xiao Yu
Contact Information	yuxiao@ion.ac.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Xiao Yu

Contact Information

yuxiao@ion.ac.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2010-10 to 2014-10 PhD: Imperial College London
Work Experience	2023-03 to Present - Chinese Academy of Sciences, Center for Excellence in Brain Science and Intelligence Technology - Researcher 2021-11 to 2022-12 - King's College London - Senior Scientist 2019-09 to 2021-10 - Boston Children's Hospital, Harvard Medical School - Postdoctoral Fellow 2014-09 to 2019-09 - Imperial College London - Postdoctoral Fellow 2013-11 to 2014-09 - Imperial College London - Research Assistant 2010-10 to 2014-10 - Imperial College London - PhD

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2010-10 to 2014-10 PhD: Imperial College London

Work Experience

2023-03 to Present - Chinese Academy of Sciences, Center for Excellence in Brain Science and Intelligence Technology - Researcher
2021-11 to 2022-12 - King's College London - Senior Scientist
2019-09 to 2021-10 - Boston Children's Hospital, Harvard Medical School - Postdoctoral Fellow
2014-09 to 2019-09 - Imperial College London - Postdoctoral Fellow
2013-11 to 2014-09 - Imperial College London - Research Assistant
2010-10 to 2014-10 - Imperial College London - PhD

Areas of Focus	Emotion Sleep Stress Instinctive Behavior
Publications	Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus, 2nd Author, 2023 Editorial: Behaviors and Neural Circuits in Sleep and Sedation, 11th Author, 2022 A specific circuit in the midbrain detects stress and induces restorative sleep, 11th Author, 2022 Nitric Oxide Synthase Neurons in the Preoptic Hypothalamus Are NREM and REM Sleep-Active and Lower Body Temperature, 4th Author, 2021 Brain Clocks, Sleep, and Mood, 1st Author, 2021 Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior, 11th Author, 2021 Genetic lesioning of histamine neurons increases sleep-wake fragmentation and reveals their contribution to modafinil-induced wakefulness, 1st Author, 2019 Galanin Neurons Unite Sleep Homeostasis and α2-Adrenergic Sedation, 3rd Author, 2019 GABA and glutamate neurons in the VTA regulate sleep and wakefulness, 1st Author, 2019 Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation, 6th Author, 2018 A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus, 2nd Author, 2018 Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems, 1st Author, 2018 Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAA Receptors with Different α Subunits, 2nd Author, 2017 Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus, 3rd Author, 2016 Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons, 5th Author, 2016 Wakefulness Is Governed by GABA and Histamine Cotransmission, 1st Author, 2015 Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists, 8th Author, 2015 The Constitutive Activation of Egr-1/C/EBPa Mediates the Development of Type 2 Diabetes Mellitus by Enhancing Hepatic Gluconeogenesis, 4th Author, 2015 Circadian Factor BMAL1 in Histaminergic Neurons Regulates Sleep Architecture, 1st Author, 2014 An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism, 2nd Author, 2011 Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice, 1st Author, 2011 Celastrol Attenuates Hypertension-Induced Inflammation and Oxidative Stress in Vascular Smooth Muscle Cells via Induction of Heme Oxygenase-1, 1st Author, 2010 Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice, 3rd Author, 2010 GABAergic Inhibition of Histaminergic Neurons Regulates Active Waking But Not the sleep-wake Switch or Propofol-Induced Loss of Consciousness, 2nd Author

Areas of Focus

Emotion
Sleep
Stress
Instinctive Behavior

Publications

Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus, 2nd Author, 2023
Editorial: Behaviors and Neural Circuits in Sleep and Sedation, 11th Author, 2022
A specific circuit in the midbrain detects stress and induces restorative sleep, 11th Author, 2022
Nitric Oxide Synthase Neurons in the Preoptic Hypothalamus Are NREM and REM Sleep-Active and Lower Body Temperature, 4th Author, 2021
Brain Clocks, Sleep, and Mood, 1st Author, 2021
Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior, 11th Author, 2021
Genetic lesioning of histamine neurons increases sleep-wake fragmentation and reveals their contribution to modafinil-induced wakefulness, 1st Author, 2019
Galanin Neurons Unite Sleep Homeostasis and α2-Adrenergic Sedation, 3rd Author, 2019
GABA and glutamate neurons in the VTA regulate sleep and wakefulness, 1st Author, 2019
Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation, 6th Author, 2018
A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus, 2nd Author, 2018
Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems, 1st Author, 2018
Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAA Receptors with Different α Subunits, 2nd Author, 2017
Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus, 3rd Author, 2016
Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons, 5th Author, 2016
Wakefulness Is Governed by GABA and Histamine Cotransmission, 1st Author, 2015
Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists, 8th Author, 2015
The Constitutive Activation of Egr-1/C/EBPa Mediates the Development of Type 2 Diabetes Mellitus by Enhancing Hepatic Gluconeogenesis, 4th Author, 2015
Circadian Factor BMAL1 in Histaminergic Neurons Regulates Sleep Architecture, 1st Author, 2014
An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism, 2nd Author, 2011
Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice, 1st Author, 2011
Celastrol Attenuates Hypertension-Induced Inflammation and Oxidative Stress in Vascular Smooth Muscle Cells via Induction of Heme Oxygenase-1, 1st Author, 2010
Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice, 3rd Author, 2010
GABAergic Inhibition of Histaminergic Neurons Regulates Active Waking But Not the sleep-wake Switch or Propofol-Induced Loss of Consciousness, 2nd Author

Emotion Sleep Stress Instinctive Behavior Neuroscience Brain Behavior Neural Circuits Mental Health Cognitive Function

Li Weidong - Shanghai Jiao Tong University

Aihua Chen - East China Normal University

Wei Zhang - Tsinghua University

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