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Yang Qien
Life Science
University of Chinese Academy of Sciences
Qinghai
Language: English, Chinese
Reproductive Biology: Reproduction
Fertility
Gametes
Embryos
Spermatogenesis
Oogenesis
Fertilization
Developmental Stages
Genetic Regulation
Cellular Processes
Developmental Biology: Development
Differentiation
Growth
Morphogenesis
Embryogenesis
Cell Signaling
Gene Expression
Tissue Formation
Organogenesis
Model Organisms
Functional Genomics: Genomics
Gene Function
Genetic Networks
Transcriptomics
Proteomics
Bioinformatics
Genetic Variation
Molecular Biology
Systems Biology
Areas of Focus
- Reproductive Biology
- Developmental Biology
- Functional Genomics
Work Experience
- 2014-12~Present - Northwest Institute of Plateau Biology, Chinese Academy of Sciences - Researcher
- 2014-05~2014-11 - Washington State University - Research Assistant Professor
- 2011-06~2014-04 - Washington State University - Postdoctoral Researcher
- 2006-08~2010-12 - University of Florida - PhD
- 2004-09~2006-07 - China Agricultural University - Master's
- 2000-09~2004-07 - China Agricultural University - Bachelor's
Academic Background & Achievements
- 2006-08--2010-12 PhD: University of Florida
- 2004-09--2006-07 Master's: China Agricultural University
- 2000-09--2004-07 Bachelor's: China Agricultural University
Publications
- Loss of PBX1 function in Leydig cells causes testicular dysgenesis and male sterility, Yang Qien, 2024
- Single-cell transcriptome analyses reveal critical regulators of spermatogonial stem cell fate transitions, Yang Qien, 2024
- Single-cell analysis identifies critical regulators of spermatogonial development and differentiation in cattle-yak bulls, Yang Qien, 2024
- Single-cell transcriptomic characterization of sheep conceptus elongation and implantation, Yang Qien, 2023
- Elevated Id2 expression causes defective meiosis and spermatogenesis in mice, Yang Qien, 2023
- Comparative proteomic analysis identifies differentially expressed proteins associated with meiotic arrest in cattle-yak hybrids, Yang Qien, 2023
- ARHGEF15 is expressed in undifferentiated spermatogonia but is not required for spermatogenesis in mice, Yang Qien, 2023
- Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression, Yang Qien, 2023
- Pancreatic lipase-related protein 2 is selectively expressed by peritubular myoid cells in the murine testis and sustains long-term spermatogenesis, Yang Qien, 2023
- Hypobaric hypoxia exposure alters transcriptome in mouse testis and impairs spermatogenesis in offspring, Yang Qien, 2022
- Long read genome assemblies complemented by single cell RNA-sequencing reveal genetic and cellular mechanisms underlying the adaptive evolution of yak, Yang Qien, 2022
- Ldha-Dependent Metabolic Programs in Sertoli Cells Regulate Spermiogenesis in Mouse Testis, Yang Qien, 2022
- Paternal hypoxia exposure impairs fertilization process and preimplantation embryo development, Yang Qien, 2021
- Transcriptome analysis revealed key signaling networks regulating ovarian activities in the domestic yak, Yang Qien, 2020
- WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche, Yang Qien, 2020
- Function and transcriptomic dynamics of Sertoli cells during prospermatogonia development in mouse testis, Yang Qien, 2020
- 青藏高原牦牛遗传资源保护和利用：问题与展望, Yang Qien, 2020
- E4 Transcription Factor 1 (E4F1) Regulates Sertoli Cell Proliferation and Fertility in Mice, Yang Qien, 2020
- The expression of histone methyltransferases and distribution of selected histone methylations in testes of yak and cattle-yak hybrid, Yang Qien, 2020
- Gene expression dynamics during the gonocyte to spermatogonia transition and spermatogenesis in the domestic yak, Yang Qien, 2019
- Gene expression dynamics during the gonocyte to spermatogonia transition and spermatogenesis in the domestic yak, Yang Qien, 2019
- Testosterone-retinoic acid signaling directs spermatogonial differentiation and seasonal spermatogenesis in the Plateau pika (Ochotona curzoniae), Yang Qien, 2019
- The CXCL12-CXCR4 signaling promotes oocyte maturation by regulating cumulus expansion in sheep, Yang Qien, 2018
- ID4 levels dictate the stem cell state in mouse spermatogonia, Yang Qien, 2017
- Conditions for Long-Term Culture of Cattle Undifferentiated Spermatogonia, Yang Qien, 2016
- The requirement for protein kinase C delta (PRKCD) during preimplantation bovine embryo development, Yang Qien, 2016
- Inactivation of Retinoblastoma Protein (Rb1) in the Oocyte: Evidence That Dysregulated Follicle Growth Drives Ovarian Teratoma Formation in Mice, Yang Qien, 2015
- Chapter Nine - Spermatogonial Stem Cell Functions in Physiological and Pathological Conditions, Yang Qien, 2014
- Functional and molecular features of the Id4 + germline stem cell population in mouse testes, Yang Qien, 2014
- Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males, Yang Qien, 2013
- Retinoblastoma Protein (RB1) Controls Fate Determination in Stem Cells and Progenitors of the Mouse Male Germline, Yang Qien, 2013
- MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells, Yang Qien, 2013
- CXCL12/CXCR4 signaling is essential for the maintenance of mouse spermatogonial stem cells, Yang Qien, 2013
- Fibroblast growth factors activate mitogen-activated protein kinase pathways to promote migration in ovine trophoblast cells, Yang Qien, 2011
- Fibroblast Growth Factor 2 Promotes Primitive Endoderm Development in Bovine Blastocyst Outgrowths, Yang Qien, 2011
- Protein Kinase C Delta Mediates Fibroblast Growth Factor-2-Induced Interferon-Tau Expression in Bovine Trophoblast, Yang Qien, 2011
- Stepwise in-straw dilution and direct transfer using open pulled straws (OPS) in the mouse: A potential model for field manipulation of vitrified embryos, Yang Qien, 2007
