Professor | Zheng Zhou | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Zheng Zhou
Contact Information	zhouzh@ibp.ac.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Zheng Zhou

Contact Information

zhouzh@ibp.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	1999-09--2003-08 Ph.D. in Science: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences 1992-09--1999-07 Bachelor's and Master's in Science: Hunan Normal University
Work Experience	2008-09~2011-09 - National Cancer Institute, National Institutes of Health, USA - Research Fellow 2003-09~2008-09 - National Cancer Institute, National Institutes of Health, USA - Visiting Fellow

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

1999-09--2003-08 Ph.D. in Science: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
1992-09--1999-07 Bachelor's and Master's in Science: Hunan Normal University

Work Experience

2008-09~2011-09 - National Cancer Institute, National Institutes of Health, USA - Research Fellow
2003-09~2008-09 - National Cancer Institute, National Institutes of Health, USA - Visiting Fellow

Areas of Focus	Epigenetic regulation of chromatin dynamics
Publications	The interplay between viral molecular mimicry and host chromatin dynamics, Xiao, Shumin, Wang, Yajing, Shan, Shan, Zhou, Zheng, 2023 Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1, Li Huang, Youwang Wang, Haizhen Long, Haoqiang Zhu, Zengqi Wen, Liwei Zhang, Wenhao Zhang, Zhenqian Guo, Longge Wang, Fangyi Tang, Jie Hu, Keyan Bao, Ping Zhu, Guohong Li, Zheng Zhou, 2023 周政：因材施教因地制宜寓研于乐, 周政, 2022 Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8, Shi, Liuxin, Huang, Li, Long, Haizhen, Song, Aoqun, Zhou, Zheng, 2022 Epstein-Barr virus protein BKRF4 restricts nucleosome assembly to suppress host antiviral responses, Jiao Chen, Zheng, 2022 Recognition of the inherently unstable H2A nucleosome by Swc2 is a major determinant for unidirectional H2A.Z exchange, Dai, Linchang, Xiao, Xue, Pan, Lu, Shi, Liuxin, Xu, Ning, Zhang, Zhuqiang, Feng, Xiaoli, Ma, Lu, Dou, Shuoxing, Wang, Pengye, Zhu, Bing, Li, Wei, Zhou, Zheng, 2021 Molecular basis for the selective recognition and ubiquitination of centromeric histone H3 by yeast E3 ligase Psh1, Zhou, Ning, Shi, Liuxin, Shan, Shan, Zhou, Zheng, 2021 Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2AZ2.2, Zhou, Min, Dai, Linchang, Li, Chengmin, Shi, Liuxin, Huang, Yan, Guo, Zhenqian, Wu, Fei, Zhu, Ping, Zhou, Zheng, 2021 Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin, Dai, Linchang, Dai, Yaxin, Han, Jinhua, Huang, Yan, Wang, Longge, Huang, Jun, Zhou, Zheng, 2021 Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing, Huang, Yan, Sun, Lu, Pierrakeas, Leonidas, Dai, Linchang, Pan, Lu, Luk, Ed, Zhou, Zheng, 2020 Mechanistic and structural insights into histone H2A-H2B chaperone in chromatin regulation, Huang, Yan, Dai, Yaxin, Zhou, Zheng, 2020 Structural basis for shieldin complex subunit 3?mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair, Dai, Yaxin, Zhang, Fan, Wang, Longge, Shan, Shan, Gong, Zihua, Zhou, Zheng, 2020 Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease, Gao, Ying, Ren, RuJing, Zhong, ZiLin, Dammer, Eric, Zhao, QianHua, Shan, Shan, Zhou, Zheng, Li, Xia, Zhang, YueQi, Cui, HaiLun, Hu, YongBo, Chen, ShengDi, Chen, JianJun, Guo, QiHao, Wang, Gang, 2019 Structural insights into histone chaperone Chz1-mediated H2A.Z recognition and histone replacement, Wang, Yunyun, Liu, Sheng, Sun, Lu, Xu, Ning, Shan, Shan, Wu, Fei, Liang, Xiaoping, Huang, Yingzi, Luk, Ed, Wu, Carl, Zhou, Zheng, 2019 Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR, Yaxin Dai, Aili Zhang, Shan Shan, Zihua Gong, Zheng Zhou, 2018 NMR investigations on H2A-H2B heterodimer dynamics conferred by histone variant H2A.Z, Dai, Linchang, Xu, Ning, Zhou, Zheng, 2019 Identification of TYR mutations in patients with oculocutaneous albinism, Sun, Wan, Shen, Yanjie, Shan, Shan, Han, Liyun, Li, Yang, Zhou, Zheng, Zhong, Zilin, Chen, Jianjun, 2018 Recent Progress in Histone Chaperones Associated With H2A-H2B Type Histones, Huang Yan, Zhou Zheng, 2018 Crystal structure of the histone heterodimer containing histone variant H2A.Bbd, Dai, Linchang, Xie, Xiaoyan, Zhou, Zheng, 2018 Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1, Liang, Xiaoping, Shan, Shan, Pan, Lu, Zhao, Jicheng, Ranjan, Anand, Wang, Feng, Zhang, Zhuqiang, Huang, Yingzi, Feng, Hanqiao, Wei, Debbie, Huang, Li, Liu, Xuehui, Zhong, Qiang, Lou, Jizhong, Li, Guohong, Wu, Carl, Zhou, Zheng, 2016 Two novel mutations in PRPF3 causing autosomal dominant retinitis pigmentosa, Zhong, Zilin, Yan, Min, Sun, Wan, Wu, Zehua, Han, Liyun, Zhou, Zheng, Zheng, Fang, Chen, Jianjun, 2016 Chromatin Assembly of Histone Variants, Zhou JuJun, Feng XiaoLi, Zhou Zheng, 2015 Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z, Mao, Zhuo, Pan, Lu, Wang, Weixiang, Sun, Jian, Shan, Shan, Dong, Qiang, Liang, Xiaoping, Dai, Linchang, Ding, Xiaojun, Chen, She, Zhang, Zhuqiang, Zhu, Bing, Zhou, Zheng, 2014 Identification of Functionally Conserved Regions in the Structure of the Chaperone/CenH3/H4 Complex, Hong, Jingjun, Feng, Hanqiao, Zhou, Zheng, Ghirlando, Rodolfo, Bai, Yawen, 2013 Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3, Zhou, Zheng, Feng, Hanqiao, Zhou, BingRui, Ghirlando, Rodolfo, Hu, Kaifeng, Zwolak, Adam, Jenkins, Lisa M Miller, Xiao, Hua, Tjandra, Nico, Wu, Carl, Bai, Yawen, 2011 Binding Kinetics of Histone Chaperone Chz1 and Variant Histone H2A.Z-H2B by Relaxation Dispersion NMR Spectroscopy, Hansen, D Flemming, Zhou, Zheng, Fen, Haniqiao, Jenkins, Lisa M Miller, Bai, Yawen, Kay, Lewis E, 2009 The High-Resolution NMR Structure of the Early Folding Intermediate of the Thermus thermophilus Ribonuclease H, Zhou, Zheng, Feng, Hanqiao, Ghirlando, Rodolfo, Bai, Yawen, 2008 NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B, Zhou, Zheng, Feng, Hanqiao, Hansen, D Flemming, Kato, Hidenori, Luk, Ed, Freedberg, Daron I, Kay, Lewis E, Wu, Carl, Bai, Yawen, 2008 Detection of a hidden folding intermediate in the focal adhesion target domain: Implications for its function and folding, Zheng Zhou, Hanqiao Feng, Yawen Bai, 2006 A protein folding pathway with multiple folding intermediates at atomic resolution, Feng, HQ, Zhou, Z, Bai, YW, 2005 Structure determination and folding pathway characterization of an engineered multi-domain protein: kinetic versus equilibrium intermediates, Zheng Zhou, 2005 The folding pathway of Rd-apocyt b562: Demonstration of the on-pathway nature of a hidden intermediate and characterization of the rate-limiting transition state by protein, Zheng Zhou, 2005

Areas of Focus

Epigenetic regulation of chromatin dynamics

Publications

The interplay between viral molecular mimicry and host chromatin dynamics, Xiao, Shumin, Wang, Yajing, Shan, Shan, Zhou, Zheng, 2023
Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1, Li Huang, Youwang Wang, Haizhen Long, Haoqiang Zhu, Zengqi Wen, Liwei Zhang, Wenhao Zhang, Zhenqian Guo, Longge Wang, Fangyi Tang, Jie Hu, Keyan Bao, Ping Zhu, Guohong Li, Zheng Zhou, 2023
周政：因材施教因地制宜寓研于乐, 周政, 2022
Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8, Shi, Liuxin, Huang, Li, Long, Haizhen, Song, Aoqun, Zhou, Zheng, 2022
Epstein-Barr virus protein BKRF4 restricts nucleosome assembly to suppress host antiviral responses, Jiao Chen, Zheng, 2022
Recognition of the inherently unstable H2A nucleosome by Swc2 is a major determinant for unidirectional H2A.Z exchange, Dai, Linchang, Xiao, Xue, Pan, Lu, Shi, Liuxin, Xu, Ning, Zhang, Zhuqiang, Feng, Xiaoli, Ma, Lu, Dou, Shuoxing, Wang, Pengye, Zhu, Bing, Li, Wei, Zhou, Zheng, 2021
Molecular basis for the selective recognition and ubiquitination of centromeric histone H3 by yeast E3 ligase Psh1, Zhou, Ning, Shi, Liuxin, Shan, Shan, Zhou, Zheng, 2021
Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2AZ2.2, Zhou, Min, Dai, Linchang, Li, Chengmin, Shi, Liuxin, Huang, Yan, Guo, Zhenqian, Wu, Fei, Zhu, Ping, Zhou, Zheng, 2021
Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin, Dai, Linchang, Dai, Yaxin, Han, Jinhua, Huang, Yan, Wang, Longge, Huang, Jun, Zhou, Zheng, 2021
Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing, Huang, Yan, Sun, Lu, Pierrakeas, Leonidas, Dai, Linchang, Pan, Lu, Luk, Ed, Zhou, Zheng, 2020
Mechanistic and structural insights into histone H2A-H2B chaperone in chromatin regulation, Huang, Yan, Dai, Yaxin, Zhou, Zheng, 2020
Structural basis for shieldin complex subunit 3?mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair, Dai, Yaxin, Zhang, Fan, Wang, Longge, Shan, Shan, Gong, Zihua, Zhou, Zheng, 2020
Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease, Gao, Ying, Ren, RuJing, Zhong, ZiLin, Dammer, Eric, Zhao, QianHua, Shan, Shan, Zhou, Zheng, Li, Xia, Zhang, YueQi, Cui, HaiLun, Hu, YongBo, Chen, ShengDi, Chen, JianJun, Guo, QiHao, Wang, Gang, 2019
Structural insights into histone chaperone Chz1-mediated H2A.Z recognition and histone replacement, Wang, Yunyun, Liu, Sheng, Sun, Lu, Xu, Ning, Shan, Shan, Wu, Fei, Liang, Xiaoping, Huang, Yingzi, Luk, Ed, Wu, Carl, Zhou, Zheng, 2019
Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR, Yaxin Dai, Aili Zhang, Shan Shan, Zihua Gong, Zheng Zhou, 2018
NMR investigations on H2A-H2B heterodimer dynamics conferred by histone variant H2A.Z, Dai, Linchang, Xu, Ning, Zhou, Zheng, 2019
Identification of TYR mutations in patients with oculocutaneous albinism, Sun, Wan, Shen, Yanjie, Shan, Shan, Han, Liyun, Li, Yang, Zhou, Zheng, Zhong, Zilin, Chen, Jianjun, 2018
Recent Progress in Histone Chaperones Associated With H2A-H2B Type Histones, Huang Yan, Zhou Zheng, 2018
Crystal structure of the histone heterodimer containing histone variant H2A.Bbd, Dai, Linchang, Xie, Xiaoyan, Zhou, Zheng, 2018
Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1, Liang, Xiaoping, Shan, Shan, Pan, Lu, Zhao, Jicheng, Ranjan, Anand, Wang, Feng, Zhang, Zhuqiang, Huang, Yingzi, Feng, Hanqiao, Wei, Debbie, Huang, Li, Liu, Xuehui, Zhong, Qiang, Lou, Jizhong, Li, Guohong, Wu, Carl, Zhou, Zheng, 2016
Two novel mutations in PRPF3 causing autosomal dominant retinitis pigmentosa, Zhong, Zilin, Yan, Min, Sun, Wan, Wu, Zehua, Han, Liyun, Zhou, Zheng, Zheng, Fang, Chen, Jianjun, 2016
Chromatin Assembly of Histone Variants, Zhou JuJun, Feng XiaoLi, Zhou Zheng, 2015
Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z, Mao, Zhuo, Pan, Lu, Wang, Weixiang, Sun, Jian, Shan, Shan, Dong, Qiang, Liang, Xiaoping, Dai, Linchang, Ding, Xiaojun, Chen, She, Zhang, Zhuqiang, Zhu, Bing, Zhou, Zheng, 2014
Identification of Functionally Conserved Regions in the Structure of the Chaperone/CenH3/H4 Complex, Hong, Jingjun, Feng, Hanqiao, Zhou, Zheng, Ghirlando, Rodolfo, Bai, Yawen, 2013
Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3, Zhou, Zheng, Feng, Hanqiao, Zhou, BingRui, Ghirlando, Rodolfo, Hu, Kaifeng, Zwolak, Adam, Jenkins, Lisa M Miller, Xiao, Hua, Tjandra, Nico, Wu, Carl, Bai, Yawen, 2011
Binding Kinetics of Histone Chaperone Chz1 and Variant Histone H2A.Z-H2B by Relaxation Dispersion NMR Spectroscopy, Hansen, D Flemming, Zhou, Zheng, Fen, Haniqiao, Jenkins, Lisa M Miller, Bai, Yawen, Kay, Lewis E, 2009
The High-Resolution NMR Structure of the Early Folding Intermediate of the Thermus thermophilus Ribonuclease H, Zhou, Zheng, Feng, Hanqiao, Ghirlando, Rodolfo, Bai, Yawen, 2008
NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B, Zhou, Zheng, Feng, Hanqiao, Hansen, D Flemming, Kato, Hidenori, Luk, Ed, Freedberg, Daron I, Kay, Lewis E, Wu, Carl, Bai, Yawen, 2008
Detection of a hidden folding intermediate in the focal adhesion target domain: Implications for its function and folding, Zheng Zhou, Hanqiao Feng, Yawen Bai, 2006
A protein folding pathway with multiple folding intermediates at atomic resolution, Feng, HQ, Zhou, Z, Bai, YW, 2005
Structure determination and folding pathway characterization of an engineered multi-domain protein: kinetic versus equilibrium intermediates, Zheng Zhou, 2005
The folding pathway of Rd-apocyt b562: Demonstration of the on-pathway nature of a hidden intermediate and characterization of the rate-limiting transition state by protein, Zheng Zhou, 2005

Epigenetics Chromatin Dna Replication Gene Transcription Dna Damage Repair Genome Stability Histone Variants Chromatin Remodeling Non-Coding Rna Cancer

Jiang Cizhong - Tongji University

Jiuhong Kang - Tongji University

Zhang He - Tongji University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us