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Bin Zhou
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Contact
Lineage Tracing Cell Plasticity Genetic Tracing Stem Cells Cell Fate Regeneration Molecular Mechanisms Intervention Strategies Cardiovascular Development Liver Regeneration
Areas of Focus
  • Lineage Tracing and Cell Plasticity
  • Genetic Lineage Tracing Technology
  • Stem Cells
Work Experience
  • 2010-09~Present - Chinese Academy of Sciences, Shanghai Institute of Life Sciences - Researcher
  • 2006-06~2010-08 - Harvard Medical School, Boston Children's Hospital - Postdoctoral Fellow, Lecturer
  • 2002-09~2006-06 - Peking Union Medical College - PhD
  • 1997-09~2002-06 - Zhejiang University School of Medicine - Bachelor's
Academic Background & Achievements
  • 2002-09--2006-06 PhD: Peking Union Medical College
  • 1997-09--2002-06 Bachelor's: Zhejiang University School of Medicine
Publications
  • Tracing the origin of alveolar stem cells in lung repair and regeneration, Bin Zhou, 2024
  • Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis, Bin Zhou, 2023
  • Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas, Bin Zhou, 2023
  • Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart, Bin Zhou, 2023
  • Bipotent transitional liver progenitor cells contribute to liver regeneration, Bin Zhou, 2023
  • Dual Genetic Lineage Tracing Reveals Capillary to Artery Formation in the Adult Heart, Bin Zhou, 2022
  • Monitoring of cell-cell communication and contact history in mammals, Bin Zhou, 2022
  • Genetic proliferation tracing reveals a rapid cell cycle withdrawal in preadolescent cardiomyocytes, Bin Zhou, 2022
  • Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair, Bin Zhou, 2021
  • Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation: Controversy, Fallacy, and Progress, Bin Zhou, 2020
  • Arterial Sca1+ vascular stem cells generate de novo smooth muscle for artery repair and regeneration, Bin Zhou, 2020
  • Reassessment of c-Kit+ Cells for Cardiomyocyte Contribution in Adult Heart, Bin Zhou, 2019
  • Genetic lineage tracing of nonmyocyte population by dual recombinases, Bin Zhou, 2018
  • Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart, Bin Zhou, 2018
  • Genetic Targeting of Organ-Specific Blood Vessels, Bin Zhou, 2018
  • Endocardial Cell Plasticity in Cardiac Development, Diseases and Regeneration, Bin Zhou, 2018
  • Preexisting endothelial cells mediate cardiac neovascularization after injury, Bin Zhou, 2017
  • Identification of a hybrid myocardial zone in the mammalian heart after birth, Bin Zhou, 2017
  • Enhancing the precision of genetic lineage tracing using dual recombinases, Bin Zhou, 2017
  • Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium, Bin Zhou, 2017
  • Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration, Bin Zhou, 2017
  • Cardiomyocyte proliferation: remove brakes and push accelerators, Bin Zhou, 2017
  • Endocardium Contributes to Cardiac Fat, Bin Zhou, 2016
  • Mfsd2a(+) hepatocytes repopulate the liver during injury and regeneration, Bin Zhou, 2016
  • Genetic lineage tracing discloses arteriogenesis as the main mechanism for collateral growth in the mouse heart, Bin Zhou, 2016
  • GATA4 regulates Fgf16 to promote heart repair after injury, Bin Zhou, 2016
  • Smooth muscle origin of postnatal 2nd CVP is pre-determined in early embryo, Bin Zhou, 2016
  • Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls, Bin Zhou, 2016
  • Genetic lineage tracing identifies endocardial origin of liver vasculature, Bin Zhou, 2016
  • Genetic targeting of sprouting angiogenesis using Apln-CreER, Bin Zhou, 2015
  • c-kit(+) cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair, Bin Zhou, 2015
  • Cellular Origin and Developmental Program of Coronary Angiogenesis, Bin Zhou, 2015
  • Genetic lineage tracing identifies in situ Kitexpressing cardiomyocytes, Bin Zhou, 2015
  • Fabp4-CreER lineage tracing revealstwo distinctive coronary vascular populations, Bin Zhou, 2014
  • De novo formation of a distinct coronary vascular population in neonatal heart, Bin Zhou, 2014
  • BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development, Bin Zhou, 2014
  • Epicardium-to-fat transition in injured heart, Bin Zhou, 2014
  • Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries, Bin Zhou, 2013
  • Peritruncal Coronary Endothelial Cells Contribute to Proximal Coronary Artery Stems and Their Aortic Orifices in the Mouse Heart, Bin Zhou, 2013
  • Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion, Bin Zhou, 2013
Awards
  • New Cornerstone Investigator (2023): Other
  • Shanghai Natural Science Award First Prize (2020): Provincial
  • XPlore Prize (2020): Other
  • International Society for Heart Research - Distinguished Investigator Award (2019): Other
  • National Ten Thousand Talents Program - Leading Talent (2018): Other
  • Royal Society of the UK - Newton Advanced Fellowship (2017): Other
  • 12th Shanghai Natural Science Peony Award (2017): Other
  • Young and Middle-aged Leading Talent in Scientific and Technological Innovation (2016): Ministerial
  • Shulan Medical Youth Award (2016): Other
  • China Youth Science and Technology Award (2015): Other
  • Top Ten Scientific Advances in China (2014): Ministerial
  • Chinese Academy of Sciences Youth Scientist Award (2015): Ministerial
  • Tan Jiazhen Life Science Innovation Award (2015): Other
  • Chinese Academy of Sciences '****' Final Evaluation Excellent (2015): Ministerial
  • Chinese Academy of Sciences '****' Final Evaluation Excellent Award (2015): Ministerial
  • Chinese Medical Science and Technology Award (2014): Other
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