Professor | Bin Zhou | Asia Growth Partners

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Name	Bin Zhou
Contact Information	zhoubin@sibs.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Bin Zhou

Contact Information

zhoubin@sibs.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2002-09--2006-06 PhD: Peking Union Medical College 1997-09--2002-06 Bachelor's: Zhejiang University School of Medicine
Work Experience	2010-09~Present - Chinese Academy of Sciences, Shanghai Institute of Life Sciences - Researcher 2006-06~2010-08 - Harvard Medical School, Boston Children's Hospital - Postdoctoral Fellow, Lecturer 2002-09~2006-06 - Peking Union Medical College - PhD 1997-09~2002-06 - Zhejiang University School of Medicine - Bachelor's
Awards	New Cornerstone Investigator (2023): Other Shanghai Natural Science Award First Prize (2020): Provincial XPlore Prize (2020): Other International Society for Heart Research - Distinguished Investigator Award (2019): Other National Ten Thousand Talents Program - Leading Talent (2018): Other Royal Society of the UK - Newton Advanced Fellowship (2017): Other 12th Shanghai Natural Science Peony Award (2017): Other Young and Middle-aged Leading Talent in Scientific and Technological Innovation (2016): Ministerial Shulan Medical Youth Award (2016): Other China Youth Science and Technology Award (2015): Other Top Ten Scientific Advances in China (2014): Ministerial Chinese Academy of Sciences Youth Scientist Award (2015): Ministerial Tan Jiazhen Life Science Innovation Award (2015): Other Chinese Academy of Sciences '**' Final Evaluation Excellent (2015): Ministerial Chinese Academy of Sciences '**' Final Evaluation Excellent Award (2015): Ministerial Chinese Medical Science and Technology Award (2014): Other

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2002-09--2006-06 PhD: Peking Union Medical College
1997-09--2002-06 Bachelor's: Zhejiang University School of Medicine

Work Experience

2010-09~Present - Chinese Academy of Sciences, Shanghai Institute of Life Sciences - Researcher
2006-06~2010-08 - Harvard Medical School, Boston Children's Hospital - Postdoctoral Fellow, Lecturer
2002-09~2006-06 - Peking Union Medical College - PhD
1997-09~2002-06 - Zhejiang University School of Medicine - Bachelor's

Awards

New Cornerstone Investigator (2023): Other
Shanghai Natural Science Award First Prize (2020): Provincial
XPlore Prize (2020): Other
International Society for Heart Research - Distinguished Investigator Award (2019): Other
National Ten Thousand Talents Program - Leading Talent (2018): Other
Royal Society of the UK - Newton Advanced Fellowship (2017): Other
12th Shanghai Natural Science Peony Award (2017): Other
Young and Middle-aged Leading Talent in Scientific and Technological Innovation (2016): Ministerial
Shulan Medical Youth Award (2016): Other
China Youth Science and Technology Award (2015): Other
Top Ten Scientific Advances in China (2014): Ministerial
Chinese Academy of Sciences Youth Scientist Award (2015): Ministerial
Tan Jiazhen Life Science Innovation Award (2015): Other
Chinese Academy of Sciences '****' Final Evaluation Excellent (2015): Ministerial
Chinese Academy of Sciences '****' Final Evaluation Excellent Award (2015): Ministerial
Chinese Medical Science and Technology Award (2014): Other

Areas of Focus	Lineage Tracing and Cell Plasticity Genetic Lineage Tracing Technology Stem Cells
Publications	Tracing the origin of alveolar stem cells in lung repair and regeneration, Bin Zhou, 2024 Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis, Bin Zhou, 2023 Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas, Bin Zhou, 2023 Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart, Bin Zhou, 2023 Bipotent transitional liver progenitor cells contribute to liver regeneration, Bin Zhou, 2023 Dual Genetic Lineage Tracing Reveals Capillary to Artery Formation in the Adult Heart, Bin Zhou, 2022 Monitoring of cell-cell communication and contact history in mammals, Bin Zhou, 2022 Genetic proliferation tracing reveals a rapid cell cycle withdrawal in preadolescent cardiomyocytes, Bin Zhou, 2022 Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair, Bin Zhou, 2021 Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation: Controversy, Fallacy, and Progress, Bin Zhou, 2020 Arterial Sca1+ vascular stem cells generate de novo smooth muscle for artery repair and regeneration, Bin Zhou, 2020 Reassessment of c-Kit+ Cells for Cardiomyocyte Contribution in Adult Heart, Bin Zhou, 2019 Genetic lineage tracing of nonmyocyte population by dual recombinases, Bin Zhou, 2018 Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart, Bin Zhou, 2018 Genetic Targeting of Organ-Specific Blood Vessels, Bin Zhou, 2018 Endocardial Cell Plasticity in Cardiac Development, Diseases and Regeneration, Bin Zhou, 2018 Preexisting endothelial cells mediate cardiac neovascularization after injury, Bin Zhou, 2017 Identification of a hybrid myocardial zone in the mammalian heart after birth, Bin Zhou, 2017 Enhancing the precision of genetic lineage tracing using dual recombinases, Bin Zhou, 2017 Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium, Bin Zhou, 2017 Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration, Bin Zhou, 2017 Cardiomyocyte proliferation: remove brakes and push accelerators, Bin Zhou, 2017 Endocardium Contributes to Cardiac Fat, Bin Zhou, 2016 Mfsd2a(+) hepatocytes repopulate the liver during injury and regeneration, Bin Zhou, 2016 Genetic lineage tracing discloses arteriogenesis as the main mechanism for collateral growth in the mouse heart, Bin Zhou, 2016 GATA4 regulates Fgf16 to promote heart repair after injury, Bin Zhou, 2016 Smooth muscle origin of postnatal 2nd CVP is pre-determined in early embryo, Bin Zhou, 2016 Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls, Bin Zhou, 2016 Genetic lineage tracing identifies endocardial origin of liver vasculature, Bin Zhou, 2016 Genetic targeting of sprouting angiogenesis using Apln-CreER, Bin Zhou, 2015 c-kit(+) cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair, Bin Zhou, 2015 Cellular Origin and Developmental Program of Coronary Angiogenesis, Bin Zhou, 2015 Genetic lineage tracing identifies in situ Kitexpressing cardiomyocytes, Bin Zhou, 2015 Fabp4-CreER lineage tracing revealstwo distinctive coronary vascular populations, Bin Zhou, 2014 De novo formation of a distinct coronary vascular population in neonatal heart, Bin Zhou, 2014 BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development, Bin Zhou, 2014 Epicardium-to-fat transition in injured heart, Bin Zhou, 2014 Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries, Bin Zhou, 2013 Peritruncal Coronary Endothelial Cells Contribute to Proximal Coronary Artery Stems and Their Aortic Orifices in the Mouse Heart, Bin Zhou, 2013 Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion, Bin Zhou, 2013

Areas of Focus

Lineage Tracing and Cell Plasticity
Genetic Lineage Tracing Technology
Stem Cells

Publications

Tracing the origin of alveolar stem cells in lung repair and regeneration, Bin Zhou, 2024
Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis, Bin Zhou, 2023
Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas, Bin Zhou, 2023
Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart, Bin Zhou, 2023
Bipotent transitional liver progenitor cells contribute to liver regeneration, Bin Zhou, 2023
Dual Genetic Lineage Tracing Reveals Capillary to Artery Formation in the Adult Heart, Bin Zhou, 2022
Monitoring of cell-cell communication and contact history in mammals, Bin Zhou, 2022
Genetic proliferation tracing reveals a rapid cell cycle withdrawal in preadolescent cardiomyocytes, Bin Zhou, 2022
Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair, Bin Zhou, 2021
Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation: Controversy, Fallacy, and Progress, Bin Zhou, 2020
Arterial Sca1+ vascular stem cells generate de novo smooth muscle for artery repair and regeneration, Bin Zhou, 2020
Reassessment of c-Kit+ Cells for Cardiomyocyte Contribution in Adult Heart, Bin Zhou, 2019
Genetic lineage tracing of nonmyocyte population by dual recombinases, Bin Zhou, 2018
Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart, Bin Zhou, 2018
Genetic Targeting of Organ-Specific Blood Vessels, Bin Zhou, 2018
Endocardial Cell Plasticity in Cardiac Development, Diseases and Regeneration, Bin Zhou, 2018
Preexisting endothelial cells mediate cardiac neovascularization after injury, Bin Zhou, 2017
Identification of a hybrid myocardial zone in the mammalian heart after birth, Bin Zhou, 2017
Enhancing the precision of genetic lineage tracing using dual recombinases, Bin Zhou, 2017
Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium, Bin Zhou, 2017
Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration, Bin Zhou, 2017
Cardiomyocyte proliferation: remove brakes and push accelerators, Bin Zhou, 2017
Endocardium Contributes to Cardiac Fat, Bin Zhou, 2016
Mfsd2a(+) hepatocytes repopulate the liver during injury and regeneration, Bin Zhou, 2016
Genetic lineage tracing discloses arteriogenesis as the main mechanism for collateral growth in the mouse heart, Bin Zhou, 2016
GATA4 regulates Fgf16 to promote heart repair after injury, Bin Zhou, 2016
Smooth muscle origin of postnatal 2nd CVP is pre-determined in early embryo, Bin Zhou, 2016
Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls, Bin Zhou, 2016
Genetic lineage tracing identifies endocardial origin of liver vasculature, Bin Zhou, 2016
Genetic targeting of sprouting angiogenesis using Apln-CreER, Bin Zhou, 2015
c-kit(+) cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair, Bin Zhou, 2015
Cellular Origin and Developmental Program of Coronary Angiogenesis, Bin Zhou, 2015
Genetic lineage tracing identifies in situ Kitexpressing cardiomyocytes, Bin Zhou, 2015
Fabp4-CreER lineage tracing revealstwo distinctive coronary vascular populations, Bin Zhou, 2014
De novo formation of a distinct coronary vascular population in neonatal heart, Bin Zhou, 2014
BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development, Bin Zhou, 2014
Epicardium-to-fat transition in injured heart, Bin Zhou, 2014
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries, Bin Zhou, 2013
Peritruncal Coronary Endothelial Cells Contribute to Proximal Coronary Artery Stems and Their Aortic Orifices in the Mouse Heart, Bin Zhou, 2013
Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion, Bin Zhou, 2013

Lineage Tracing Cell Plasticity Genetic Tracing Stem Cells Cell Fate Regeneration Molecular Mechanisms Intervention Strategies Cardiovascular Development Liver Regeneration

Xudong Guo - Tongji University

Juan Tang - Tongji University

Guiying Wang - Tongji University

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