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Shuwen Zhang
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English, German
Disordered Proteins
Phase Separation
Synaptic Plasticity
Autism
Molecular Mechanisms
Neurodevelopment
Synaptic Transmission
Transgenic Mice
Two-Photon Imaging
Electrophysiology
Areas of Focus
- Disordered Protein Phase Separation and Synaptic Plasticity
- Molecular Mechanisms of Autism
- Neurodevelopmental Disorders
Work Experience
- 2014.1-2017.3 - Charité Hospital, Berlin, Germany - Postdoctoral Researcher
- 2017.7-2017.12 - Max Planck Institute, Göttingen, Germany - Postdoctoral Researcher
- 2019.1-2020.10 - Hospital for Sick Children, Toronto, Canada - Postdoctoral Researcher
Publications
- The gut metabolite indole-3-propionic acid activates ERK1 to restore social function and hippocampal inhibitory synaptic transmission in a 16p11.2 microdeletion mouse model, Shuwen Zhang, 2024
- Munc13-1 is a calcium phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission, Shuwen Zhang, 2021
- Synaptotagmin-1 drives synchronous Ca2+-triggered fusion by C2B-domain-mediated synaptic-vesicle-membrane attachment, Shuwen Zhang, 2018
- Heterodimerization of Munc13 C 2 A domain with RIM regulates synaptic vesicle docking and priming, Shuwen Zhang, 2017
- Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons, Shuwen Zhang, 2016
- Complexin Stabilizes Newly Primed Synaptic Vesicles and Prevents Their Premature Fusion at the Mouse Calyx of Held Synapse, Shuwen Zhang, 2015
