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Zhenfeng Zhang
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Extremophiles
Genetic Mechanisms
Synthetic Biology
Archaea
Viruses
Dna Replication
Dna Repair
Chromosome Organization
Host Cell Lysis
Thermophiles
Areas of Focus
- Genetic mechanisms of extremophiles
- Synthetic biology of extremophiles
- Archaeal viruses
Work Experience
- 2010-07~2020-06 - Chinese Academy of Sciences, Institute of Microbiology - Associate Researcher
- 2007-03~2010-07 - Chinese Academy of Sciences, Institute of Microbiology - Assistant Researcher
Academic Background & Achievements
- 2001-09--2006-12 Ph.D.: Nankai University
- 1997-09--2001-07 Bachelor's: Shandong University
Publications
- Lysine Methylation Modulates the Interaction of Archaeal Chromatin Protein Cren7 With DNA, Corresponding Author, 2022
- Essentiality of core hydrophobicity to the structure and function of archaeal chromatin protein Cren7, Corresponding Author, 2022
- A Novel Family of Winged-Helix Single-Stranded DNA-Binding Proteins from Archaea, Corresponding Author, 2022
- Biochemical and structural characterization of a KTSC family single-stranded DNA-binding protein from Euryarchaea, Corresponding Author, 2022
- Isolation and Characterization of the First Temperate Virus Infecting Psychrobacillus from Marine Sediments, 4th Author, 2022
- Interaction of the Escherichia coli HU Protein with Various Topological Forms of DNA, 2nd Author, 2021
- Archaeal Chromatin Proteins Cren7 and Sul7d Compact DNA by Bending and Bridging, 1st Author, 2020
- Inhibition of K-Ras4B-plasma membrane association with a membrane microdomain-targeting peptide, 2nd Author, 2020
- 探秘生命的第三种形式--我国古菌研究之回顾与展望, 7th Author, 2019
- Architectural roles of Cren7 in folding crenarchaeal chromatin filament, 1st Author, 2019
- Novel Sulfolobus Virus with an Exceptional Capsid Architecture, 9th Author, 2018
- Roles of leu28 side chain intercalation in the interaction between cren7 and dna, 1st Author, 2017
- Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea, 2nd Author, 2016
- Genome Sequencing of Sulfolobus sp. A20 from Costa Rica and Comparative Analyses of the Putative Pathways of Carbon, Nitrogen, and Sulfur Metabolism in Various Sulfolobus Strains, 3rd Author, 2016
- Akmt catalyzes extensive protein lysine methylation in the hyperthermophilic archaeon sulfolobus islandicus but is dispensable for the growth of the organism, 5th Author, 2016
- Cleavage of The Double-strand Region in Alkali-denatured Supercoiled Plasmid pBR322 Leads to DNA Nodes, Corresponding Author, 2016
- DNA Condensation Induced by Transciption of tet A-cfa ABCE in Escherichia coli topA Mutant, Corresponding Author, 2015
- Insights into the interaction between Cren7 and DNA: the role of loop beta 3-beta 4, 1st Author, 2015
- Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase, 4th Author, 2012
- Archaeal chromatin proteins, 1st Author, 2012
- Identification and Characterization of a Highly Conserved Crenarchaeal Protein Lysine Methyltransferase with Broad Substrate Specificity, 2nd Author, 2012
- Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA, 1st Author, 2010
- 在拓扑异构酶Ⅰ缺失的大肠杆菌中拓扑异构酶Ⅲ参与高负超螺旋的消除, 1st Author, 2009
- Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea, 3rd Author, 2008
- Visualization of alkali-denatured supercoiled plasmid DNA by atomic force microscopy, 2nd Author, 2008
- 大肠杆菌topA-菌株中质粒pBR322的超凝集结构, 1st Author, 2007
Awards
- CAS Distinguished Research Fellow (2021): Institute (School)
- Outstanding Editor Award (2021): Frontiers in Microbiology
- Best Poster Award (2013): Thermophiles 2013
- Best Poster Award (2009): Thermophiles 2009
