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Li Zhu
zhuli@ibp.ac.cn
English, Chinese
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2003-12 to 2009-06 Postdoctoral Researcher: University of Texas Southwestern Medical Center
  • 1998-09 to 2003-07 Ph.D. in Science: Institute of Biophysics, Chinese Academy of Sciences
  • 1992-09 to 1996-06 Bachelor's in Biochemistry: Beijing Normal University
  • 2003-12 to 2009-06 - University of Texas Southwestern Medical Center - Postdoctoral Researcher
  • Beijing Science and Technology Award (2022): Second Prize, 2023
  • Outstanding Editorial Board Member of 'Progress in Biochemistry and Biophysics' (2022)
  • Postdoctoral Fellowship from the Dystonia Medical Research Foundation (2006)
  • Liu Yongling Scholarship from the Chinese Academy of Sciences (2001): Second Prize
  • Outstanding Graduate of Beijing Higher Education Institutions (1996)
  • Beijing Sanhao Student (1994)
Molecular mechanisms of cognitive impairment and related brain diseases
Mechanisms and interventions for neurodegenerative diseases
Mitochondrial homeostasis imbalance and neurodegenerative diseases
Protein homeostasis and diseases
  • Integration of FUNDC1-associated mitochondrial protein import and mitochondrial quality control contributes to TDP-43 degradation, Ma, Jinfa, Liu, Lei, Song, Lu, Liu, Jianghong, Yang, Lingyao, Chen, Quan, WU, JANE Y, Zhu, Li, 2023
  • 线粒体蛋白CHCHD10与神经退行性疾病, 王腈, 朱笠, 2023
  • Protein aggregation and phase separation in TDP-43 associated neurodegenerative diseases, Shi, Lijun, Xu, Anqi, Zhu, Li, 2022
  • 蛋白质和多肽的检测与疾病诊疗, 柯莎, 朱笠, 2022
  • Detection of orthologous exons and isoforms using EGIO, Ma, Jinfa, Jane Y. Wu, Zhu, Li, 2022
  • Diagnostic Value of Salivary Real-Time Quaking-Induced Conversion in Parkinson's Disease and Multiple System Atrophy, Luan, Mingyue, Sun, Yunchuang, Chen, Jing, Jiang, Yanyan, Li, Fan, Wei, Luhua, Sun, Wei, Ma, Jinfa, Song, Lu, Liu, Jianghong, Liu, Bing, Pei, Yaohua, Wang, Zhaoxia, Zhu, Li, Deng, Jianwen, 2022
  • DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors, Peng Chen, Ziyang Liu, Qian Zhang, Dong Lin, Lu Song, Jianghong Liu, HuiFeng Jiao, Xinsheng Lai, Suqi Zou, Shunqi Wang, Tian Zhou, BaoMing Li, Li Zhu, BingXing Pan, Erkang Fei, 2022
  • MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking, Wang, Fei, Chen, Xiaoping, Cheng, Haipeng, Song, Lu, Liu, Jianghong, Caplan, Steve, Zhu, Li, Wu, Jane Y, 2021
  • Tunneling Nanotube: a Novel Type of Signal Transmission in The Nervous System, Wang Fei, Zhang Yan, Zhu Li, 2021
  • TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response, Peng Wang, Jianwen Deng, Jie Dong, Jianghong Liu, Eileen H Bigio, Marsel Mesulam, Tao Wang, Lei Sun, Li Wang, Alan YuehLuen Lee, Warren A McGee, Xiaoping Chen, Kazuo Fushimi, Li Zhu, Jane Y Wu, 2019
  • TDP-43 regulates cancer-associated microRNAs, Chen, Xiaowei, Fan, Zhen, McGee, Warren, Chen, Mengmeng, Kong, Ruirui, Wen, Pushuai, Xiao, Tengfei, Chen, Xiaomin, Liu, Jianghong, Zhu, Li, Chen, Runsheng, Wu, Jane Y, 2018
  • Measure and model a 3-D space-variant PSF for fluorescence microscopy image deblurring, Chen, Yemeng, Chen, Mengmeng, Zhu, Li, Wu, Jane Y, Du, Sidan, Li, Yang, 2018
  • FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models, Deng, Jianwen, Wang, Peng, Chen, Xiaoping, Cheng, Haipeng, Liu, Jianghong, Fushimi, Kazuo, Zhu, Li, Wu, Jane Y, 2018
  • MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2, Zhang, Yunjia, Chen, Mengmeng, Qiu, Zilong, Hu, Keping, McGee, Warren, Chen, Xiaoping, Liu, Jianghong, Zhu, Li, Wu, Jane Y, 2016
  • PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration, Chen, Yanbo, Deng, Jianwen, Wang, Peng, Yang, Mengxue, Chen, Xiaoping, Zhu, Li, Liu, Jianghong, Lu, Bingwei, Shen, Yan, Fushimi, Kazuo, Xu, Qi, Wu, Jane Y, 2016
  • 与神经退行性疾病相关的RNA结合蛋白在线粒体损伤中的作用, 朱笠, 邓健文, 王鹏, 刘江红, Jane Y. Wu, 2016
  • Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism, Yi, Fengshuang, Kong, Ruirui, Ren, Jinqi, Zhu, Li, Lou, Jizhong, Wu, Jane Y, Feng, Wei, 2016
  • A new method for quantifying mitochondrial axonal transport, Chen, Mengmeng, Li, Yang, Yang, Mengxue, Chen, Xiaoping, Chen, Yemeng, Yang, Fan, Lu, Sheng, Yao, Shengyu, Zhou, Timothy, Liu, Jianghong, Zhu, Li, Du, Sidan, Wu, Jane Y, 2016
  • USP33 mediates Slit- Robo signaling in inhibiting colorectal cancer cell migration, Huang, Zhaohui, Wen, Pushuai, Kong, Ruirui, Cheng, Haipeng, Zhang, Binbin, Quan, Cao, Bian, Zehua, Chen, Mengmeng, Zhang, Zhenfeng, Chen, Xiaoping, Du, Xiang, Liu, Jianghong, Zhu, Li, Fushimi, Kazuo, Hua, Dong, Wu, Jane Y, 2015
  • Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression, Kong, Ruirui, Yi, Fengshuang, Wen, Pushuai, Liu, Jianghong, Chen, Xiaoping, Ren, Jinqi, Li, Xiaofei, Shang, Yulong, Nie, Yongzhan, Wu, Kaichun, Fan, Daiming, Zhu, Li, Feng, Wei, Wu, Jane Y, 2015
  • FUS Interacts with HSP60 to Promote Mitochondrial Damage, Deng, Jianwen, Yang, Mengxue, Chen, Yanbo, Chen, Xiaoping, Liu, Jianghong, Sun, Shufeng, Cheng, Haipeng, Li, Yang, Bigio, Eileen H, Mesulam, Marsel, Xu, Qi, Du, Sidan, Fushimi, Kazuo, Zhu, Li, Wu, Jane Y, 2015
  • Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation, Xu, Yiliang, Sun, Yuhui, Ye, Haihong, Zhu, Li, Liu, Jianghong, Wu, Xiaofeng, Wang, Le, He, Tingting, Shen, Yan, Wu, Jane Y, Xu, Qi, 2015
  • USP33, a new player in lung cancer, mediates Slit-Robo signaling, Wen, Pushuai, Kong, Ruirui, Liu, Jianghong, Zhu, Li, Chen, Xiaoping, Li, Xiaofei, Nie, Yongzhan, Wu, Kaichun, Wu, Jane Y, 2014
  • RNA-binding proteins in neurological diseases, Zhou HuaLin, Mangelsdorf, Marie, Liu JiangHong, Zhu Li, Wu, Jane Y, 2014
  • AxonQuant: A Microfluidic Chamber Culture-Coupled Algorithm That Allows High-Throughput Quantification of Axonal Damage, Li, Yang, Yang, Mengxue, Huang, Zhuo, Chen, Xiaoping, Maloney, Michael T, Zhu, Li, Liu, Jianghong, Yang, Yanmin, Du, Sidan, Jiang, Xingyu, Wu, Jane Y, 2014
  • An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel beta-structure and induces TDP-43 redistribution, Zhu, Li, Xu, Meng, Yang, Mengxue, Yang, Yanlian, Li, Yang, Deng, Jianwen, Ruan, Linhao, Liu, Jianghong, Du, Sidan, Liu, Xuehui, Feng, Wei, Fushimi, Kazuo, Bigio, Eileen H, Mesulam, Marsel, Wang, Chen, Wu, Jane Y, 2014
  • AMPK interacts with DSCAM and plays an important role in Netrin-1 induced neurite outgrowth, Zhu, Kun, Chen, Xiaoping, Liu, Jianghong, Ye, Haihong, Zhu, Li, Wu, Jane Y, 2013
  • Characterization of beta-domains in C-terminal fragments of TDP-43 by scanning tunneling microscopy, Xu, Meng, Zhu, Li, Liu, Jianghong, Yang, Yanlian, Wu, Jane Y, Wang, Chen, 2013
  • 1.270 A UNIQUE REDOX-SENSING SENSOR-II MOTIF IN TORSINA PLAYS A CRITICAL ROLE IN NUCLEOTIDE AND PARTNER BINDING, Zhu, Li, L. Millen, J.L. Mendoza, P.J. Thomas, 2012
  • 转录后基因调控异常与老年性痴呆, 朱笠, 刘江红,
Cognitive Impairment Brain Diseases Molecular Mechanisms Neurodegenerative Diseases Interventions Mitochondrial Homeostasis Protein Homeostasis Disease Mechanisms Brain Research Biochemistry

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