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Ying Cao
Life Science
Tongji University
Shanghai
Language: Chinese, English
Contact
Cilia Genetics Kidney Development Kidney Disease Rare Diseases Ciliopathies Renal Stem Cells Zebrafish Model Crispr/Cas9 Signal Pathways
Areas of Focus
  • Identification and functional study of new ciliary factors
  • Mechanisms of kidney development and kidney diseases
  • Mechanisms of other human rare diseases/ciliopathies
  • Research on renal stem cells
Work Experience
  • 2005-2010 - Postdoctoral Researcher, Department of Genetics, Yale University School of Medicine
  • 2010-present - Professor, School of Life Sciences and Technology, Tongji University
Academic Background & Achievements
  • 2000 - BSc in Biological Sciences and Technology, Tsinghua University
  • 2005 - PhD in Cell and Developmental Biology, Tsinghua University
  • Research on FGF signaling pathway in zebrafish embryonic development during PhD
Publications
  • Mutagenesis of ciliary candidate genes with CRISPR/Cas9 system in zebrafish identifies genes required for retina development, Ying Cao et al., 2019
  • Apical PtdIns(4,5)P2 is required for ciliogenesis and suppression of polycystic kidney disease, Ying Cao et al., 2019
  • Identification and Functional Studies of MYO1H for Mandibular Prognathism, Ying Cao et al., 2018
  • Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels, Ying Cao et al., 2018
  • Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway, Ying Cao et al., 2018
  • Using local chromatin structure to improve CRISPR/Cas9 efficiency in zebrafish, Ying Cao et al., 2017
  • The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane, Ying Cao et al., 2017
  • Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity, Ying Cao et al., 2010
  • Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models, Ying Cao et al., 2009
  • A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida, Ying Cao et al., 2007
  • fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos, Ying Cao et al., 2004
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