Professor | Ying Cao | Asia Growth Partners

Name	Ying Cao
Contact Information	yingcao@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Ying Cao

Contact Information

yingcao@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2000 - BSc in Biological Sciences and Technology, Tsinghua University 2005 - PhD in Cell and Developmental Biology, Tsinghua University Research on FGF signaling pathway in zebrafish embryonic development during PhD
Work Experience	2005-2010 - Postdoctoral Researcher, Department of Genetics, Yale University School of Medicine 2010-present - Professor, School of Life Sciences and Technology, Tongji University

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2000 - BSc in Biological Sciences and Technology, Tsinghua University
2005 - PhD in Cell and Developmental Biology, Tsinghua University
Research on FGF signaling pathway in zebrafish embryonic development during PhD

Work Experience

2005-2010 - Postdoctoral Researcher, Department of Genetics, Yale University School of Medicine
2010-present - Professor, School of Life Sciences and Technology, Tongji University

Areas of Focus	Identification and functional study of new ciliary factors Mechanisms of kidney development and kidney diseases Mechanisms of other human rare diseases/ciliopathies Research on renal stem cells
Publications	Mutagenesis of ciliary candidate genes with CRISPR/Cas9 system in zebrafish identifies genes required for retina development, Ying Cao et al., 2019 Apical PtdIns(4,5)P2 is required for ciliogenesis and suppression of polycystic kidney disease, Ying Cao et al., 2019 Identification and Functional Studies of MYO1H for Mandibular Prognathism, Ying Cao et al., 2018 Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels, Ying Cao et al., 2018 Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway, Ying Cao et al., 2018 Using local chromatin structure to improve CRISPR/Cas9 efficiency in zebrafish, Ying Cao et al., 2017 The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane, Ying Cao et al., 2017 Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity, Ying Cao et al., 2010 Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models, Ying Cao et al., 2009 A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida, Ying Cao et al., 2007 fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos, Ying Cao et al., 2004

Areas of Focus

Identification and functional study of new ciliary factors
Mechanisms of kidney development and kidney diseases
Mechanisms of other human rare diseases/ciliopathies
Research on renal stem cells

Publications

Mutagenesis of ciliary candidate genes with CRISPR/Cas9 system in zebrafish identifies genes required for retina development, Ying Cao et al., 2019
Apical PtdIns(4,5)P2 is required for ciliogenesis and suppression of polycystic kidney disease, Ying Cao et al., 2019
Identification and Functional Studies of MYO1H for Mandibular Prognathism, Ying Cao et al., 2018
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels, Ying Cao et al., 2018
Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway, Ying Cao et al., 2018
Using local chromatin structure to improve CRISPR/Cas9 efficiency in zebrafish, Ying Cao et al., 2017
The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane, Ying Cao et al., 2017
Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity, Ying Cao et al., 2010
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models, Ying Cao et al., 2009
A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida, Ying Cao et al., 2007
fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos, Ying Cao et al., 2004

Cilia Genetics Kidney Development Kidney Disease Rare Diseases Ciliopathies Renal Stem Cells Zebrafish Model Crispr/Cas9 Signal Pathways

Ying Cao - Tongji University

Lin He - East China Normal University

Lei Wang - Southern University of Science and Technology

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