Areas of Focus
- Protein Expression Systems
- Microbial Enzymology
- Molecular Structure of Protein Complexes
Work Experience
- 2014-05~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Associate Researcher
- 2010-09~2014-04 - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Assistant Researcher
- 2007-10~2008-09 - International University Bremen - Exchange
Academic Background & Achievements
- 2007-10--2008-09 Exchange: International University Bremen
- 2006-09-- PhD: Institute of Microbiology, Chinese Academy of Sciences
- 2004-09-- Master's: Nanjing University of Science and Technology
- 2000-09-- Bachelor's: Nanjing University of Science and Technology
Publications
- Application-oriented structure and function study of proteins: a review, Fourth Author, 2022
- Developments of core technologies in industrial enzymes and green bioprocessing, Fourth Author, 2022
- Recombinant expression of milk proteins and biosynthesis of animal-free milk: analysis on related patents and trend for technology development, Sixth Author, 2021
- Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediates, Seventh Author, 2020
- Structure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate, Fifth Author, 2020
- High expression and characterization of a novel zearalenone hydrolase from Rhinocladiella mackenziei in Pichia pastoris, Seventh Author, 2020
- Structure of a gut microbial diltiazem-metabolizing enzyme suggests possible substrate binding mode, Fifth Author, 2020
- Expression, Purification and Crystallization of a Glycoside Hydrolase Family 5 Endoglucanase (AnCel5A) from Aspergillus niger, Third Author, 2019
- Molecular Engineering of Mycoestrogen-Detoxifying Lactonase ZHD101 to Improve Enzyme Thermostability, Sixth Author, 2019
- Discovery of Lipophilic Bisphosphonates that Target Bacterial Cell Wall and Quinone Biosynthesis, First Author, 2019
- Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity, First Author, 2018
- Expression, purification and characterization of a novel zearalenone hydrolase from Rhinocladiella mackenziei, Seventh Author, 2018
- Fusion Expression of Dehydrosqualene Desaturase (CrtN) from Staphylococcus aureus and DNA Binding Protein Sso7d, Second Author, 2018
- The Lysine 299 Residue Endows the Multisubunit Mrp1 Antiporter with Dominant Roles in Na+ Resistance and pH Homeostasis in Corynebacterium glutamicum, Second Author, 2018
- The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement, Seventh Author, 2018
- Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris, Sixth Author, 2017
- Characterization and crystal structure of a novel zearalenone hydrolase from Cladophialophora bantiana, Fifth Author, 2017
- Structural insight into catalytic mechanism of PET hydrolase, Fifth Author, 2017
- Characterization and crystal structure of a novel zearalenone hydrolase from Cladophialophora bantiana, Fifth Author, 2017
- Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyl Transferase MoeN5, Fifth Author, 2016
- Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase, First Author, 2016
- Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50, Fifth Author, 2016
- Functional and structural analyses of a 1,4-beta-endoglucanase from Ganoderma lucidum, Seventh Author, 2016
- Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyl Transferase MoeN5, Fifth Author, 2016
- Enhanced alpha-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering, Eleventh Author, 2016
- Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Antiparasitic Drug Targets, Not mentioned, 2016
- Structure and Function of a 'Head-to-Middle' Prenyltransferase: Lavandulyl Diphosphate Synthase, Fifth Author, 2016
- Functional and structural analysis of Pichia pastoris-expressed Aspergillus niger 1,4-beta-endoglucanase, Fifth Author, 2016
- Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+), NADPH, or NAD(+)/10-Oxogeranial: Reaction Mechanisms, Fourth Author, 2015
- Binding mode of the oxidized alpha-anomer of NAD(+) to RSP, a Rex-family repressor. Biochem Biophys Res Commun., First Author, 2015
- Binding mode of the oxidized alpha-anomer of NAD(+) to RSP, a Rex-family repressor, First Author, 2015
- Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms, Fifth Author, 2015
- Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima, First Author, 2015
- Preliminary X-ray diffraction analysis of thermostable beta-1,4-xylanase from Streptomyces sp S9, Ninth Author, 2014
- Preliminary X-ray diffraction analysis of thermostable beta-1,4-xylanase from Streptomyces sp. S9, Ninth Author, 2014
- Structural and Functional Analysis of Bacillus subtilis YisP Reveals a Role of Its Product in Biofilm Production, Third Author, 2014
- Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms, Eighth Author, 2014
- Crystallization and preliminary X-ray diffraction analysis of the S-adenosylhomocysteine hydrolase (SAHH) from Thermotoga maritima, Second Author, 2014
- Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum, Third Author, 2014
- Preliminary X-ray diffraction analysis of a thermophilic beta-1,3-1,4-glucanase from Clostridium thermocellum, Sixth Author, 2014
- Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis, Sixth Author, 2014
- Structural perspectives of an engineered beta-1,4-xylanase with enhanced enhanced thermostability, Tenth Author, 2014
- Crystal structure and substrate-binding mode of the mycoestrogen-detoxifying lactonase ZHD from Clonostachys rosea, Fourth Author, 2014
- Preliminary X-ray diffraction analysis of thermostable beta-1,4-xylanase from Streptomyces sp S9, Ninth Author, 2014
- Functional and structural studies of pullulanase from Anoxybacillus sp. LM18-11, Fourth Author, 2014
- Crystallization and preliminary X-ray diffraction analysis of the S-adenosylhomocysteine hydrolase (SAHH) from Thermotoga maritima, Second Author, 2014
- Squalene Synthase As a Target for Chagas Disease Therapeutics, Sixth Author, 2014
- Functional and structural studies of pullulanase from Anoxybacillus sp. LM18-11., Not mentioned, 2014
- Preliminary X-ray diffraction analysis of a thermophilic beta-1,3-1,4-glucanase from Clostridium thermocellum, Sixth Author, 2014
- Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes, First Author, 2014
- Structural perspectives of an engineered beta-1,4-xylanase with enhanced thermostability, Thirteenth Author, 2014
- Crystallization and preliminary X-ray diffraction analysis of YisP protein from Bacillus subtilis subsp subtilis strain 168, Eighth Author
Awards
- Tianjin Natural Science Award Second Prize (2019): Second Prize