Areas of Focus
- Neural Stem Cells
- Epigenetics
- Neurodevelopmental Disorders
- Autism
- Cognitive Impairment
- Neural Injury Repair
Work Experience
- 2014-10 - Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
- 2011-05 - Present - Johns Hopkins University School of Medicine - Postdoctoral
- 2008-04 - Present - University of New Mexico, Department of Neurobiology - Postdoctoral
- 2004-07 - Present - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
- 2001-08 - Present - Peking Union Medical College - PhD
Academic Background & Achievements
- 2001-08 - PhD: Peking Union Medical College
Publications
- Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury, Chang-Mei Liu, 2023
- ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-β signaling pathway, Chang-Mei Liu, 2023
- Chemotherapy for early-stage breast cancer: the more the better?, Chang-Mei Liu, 2023
- Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, Chang-Mei Liu, 2023
- Neuronal Histone Methyltransferase EZH2 Regulates Neuronal Morphogenesis, Synaptic Plasticity, and Cognitive Behavior in Mice, Chang-Mei Liu, 2023
- The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury, Chang-Mei Liu, 2023
- The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis, Chang-Mei Liu, 2022
- Mouse model of voluntary movement deficits induced by needlestick injuries to the primary motor cortex, Chang-Mei Liu, 2022
- Abnormal microglial polarization induced by Arid1a deletion leads to neuronal differentiation deficits, Chang-Mei Liu, 2022
- Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, Chang-Mei Liu, 2022
- Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury, Chang-Mei Liu, 2022
- A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, Chang-Mei Liu, 2022
- KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs, Chang-Mei Liu, 2022
- Loss of microglial EED impairs synapse density, learning, and memory, Chang-Mei Liu, 2022
- Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development, Chang-Mei Liu, 2022
- miR-26a promotes axon regeneration in the mammalian central nervous system by suppressing PTEN expression, Chang-Mei Liu, 2021
- Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration, Chang-Mei Liu, 2021
- TREM2, microglia, and Alzheimer’s disease, Chang-Mei Liu, 2021
- Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters, Chang-Mei Liu, 2021
- Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development, Chang-Mei Liu, 2021
- Strategies to Promote Long-Distance Optic Nerve Regeneration, Chang-Mei Liu, 2020
- Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury, Chang-Mei Liu, 2020
- Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2, Chang-Mei Liu, 2020
- Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, Chang-Mei Liu, 2020
- UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters, Chang-Mei Liu, 2020
- SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury, Chang-Mei Liu, 2020
- GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells, Chang-Mei Liu, 2019
- The Role of Non-Coding RNAs in Neurodevelopmental Disorders, Chang-Mei Liu, 2019
- Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus, Chang-Mei Liu, 2019
- MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice, Chang-Mei Liu, 2019
- GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells, Chang-Mei Liu, 2019
- Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration, Chang-Mei Liu, 2018
- Commentary: Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus., Chang-Mei Liu, 2018
- Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration., Chang-Mei Liu, 2018
- Wnt3 and Gata4 regulate axon regeneration in adult mouse DRG neurons, Chang-Mei Liu, 2018
- Partial loss of psychiatric risk gene miR-137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a, Chang-Mei Liu, 2018
- Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System, Chang-Mei Liu, 2018
- MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells, Chang-Mei Liu, 2017
- The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice., Chang-Mei Liu, 2017
- Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury, Chang-Mei Liu, 2016
- MicroRNA-26a supports mammalian axon regeneration in vivo by suppressing GSK3β expression., Chang-Mei Liu, 2015
- Akt-independent GSK3 inactivation downstream of PI3K signaling regulates mammalian axon regeneration., Chang-Mei Liu, 2014
- An Epigenetic Feedback Regulatory Loop Involving MicroRNA-195 and MBD1 Governs Neural Stem Cell Differentiation, Chang-Mei Liu, 2013
- MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration, Chang-Mei Liu, 2013
- PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1, Chang-Mei Liu, 2013
- RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression., Chang-Mei Liu, 2011
- Inhibition of Atrogin-1/MAFbx Expression by Adenovirus-Delivered Small Hairpin RNAs Attenuates Muscle Atrophy in Fasting Mice, Chang-Mei Liu, 2011
- Epigenetic Regulation of miR-184 by MBD1 Governs Neural Stem Cell Proliferation and Differentiation, Chang-Mei Liu, 2010
- Construction and identification of the human liver-specific miR-122 expression vector, Chang-Mei Liu, 2009
- The Influence of pH Value on the Absorption of RNA Interference Oligos of FOXO1 and GDF-8 Gene, Chang-Mei Liu, 2009
- A retrovirus-based system to stably silence gdf-8 expression and enhance myogenic differentiation in human rhabdomyosarcoma cells, Chang-Mei Liu, 2008
- Inhibiting GDF-8 Expression by Retrovirus-Based RNAi Stably, Chang-Mei Liu, 2008
- Recombinant protein of heptad-repeat HR
Awards
- Key Research Project Chief, First Prize, National Level, 2021
- Final Evaluation Excellence Award, First Prize, Ministerial Level, 2019
