Professor | Kaixia Mi | Asia Growth Partners

Name	Kaixia Mi
Contact Information	mik@im.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Kaixia Mi

Contact Information

mik@im.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1999-2003 PhD in Genetics: Institute of Microbiology, Chinese Academy of Sciences
Work Experience	2009-present - Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology - Group Leader 2004-2009 - Albert Einstein College of Medicine - Research Assistant 2003-2004 - Texas University Health Science Center San Antonio - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1999-2003 PhD in Genetics: Institute of Microbiology, Chinese Academy of Sciences

Work Experience

2009-present - Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology - Group Leader
2004-2009 - Albert Einstein College of Medicine - Research Assistant
2003-2004 - Texas University Health Science Center San Antonio - Postdoctoral Researcher

Areas of Focus	Pathogenic Microorganisms Latent Infection and Drug Resistance Mechanisms of Mycobacterium tuberculosis
Publications	Trends and challenges of multi-drug resistance in childhood tuberculosis, Zhuang, Zengfang, Sun, Lin, Song, Xiaorui, Zhu, Hanzhao, Li, Lianju, Zhou, Xintong, Mi, Kaixia, 2023 Advances of new drugs bedaquiline and delamanid in the treatment of multi-drug resistant tuberculosis in children, Zhu, Hanzhao, Zhou, Xintong, Zhuang, Zengfang, Li, Lianju, Bi, Jing, Mi, Kaixia, 2023 The impact of global warming on the signature virulence gene, thermolabile hemolysin, of Vibrio parahaemolyticus, Weishan Zhang, Keyu Chen, Mi Kaixia, 2023 Coevolution of furA-Regulated Hyper-Inflammation and Mycobacterial Resistance to Oxidative Killing through Adaptation to Hydrogen Peroxide, Fan, Xin, Zhao, Bei, Zhang, Weishan, Li, Ning, Mi, Kaixia, Wang, Beinan, 2023 Experimental Evolution Reveals Redox State Modulates Mycobacterial Pathogenicity, Jiang, Zheng, Zhuang, Zengfang, Mi, Kaixia, 2022 The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility, Xinling Hu, Xintong Zhou, Tong Yin, Keyu Chen, Yongfei Hu, Baoli Zhu, Kaixia Mi, 2021 新型冠状病毒对冷链运输食品质量安全的影响, 张玮珊, 胡新玲, 律娜, 米凯霞, 2021 后基因组时代诺如病毒的研究进展, 张玮珊, 胡新玲, 律娜, 徐颖华, 米凯霞, 2021 The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic, Feng, Lipeng, Mundy, Julia E A, Stevenson, Clare E M, Mitchenall, Lesley A, Lawson, David M, Mi, Kaixia, Maxwell, Anthony, 2021 结核病和微生物菌群的关系, 裴佳宾, 杨雨媛, 周心童, 胡格, 王雪涵, 郭勇, 米凯霞, 2020 The plasmid-borne quinolone resistance protein QnrB, a novel DnaA-binding protein, increases the bacterial mutation rate by triggering DNA replication stress, Li, Xiaojing, Zhang, Yujiao, Zhou, Xintong, Hu, Xinling, Zhou, Yixuan, Liu, Di, Maxwell, Anthony, Mi, Kaixia, 2019 分枝杆菌丝氨酸/苏氨酸蛋白激酶PknK的功能研究, 周怡璇, 周心童, 杨健, 胡新玲, 米凯霞, 2019 结核病疫苗和耻垢分枝杆菌引起树突状细胞差异免疫反应的蛋白质组学分析, 霍祎, 宗兆运, 米凯霞, 邓海腾, 2018 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target, Zhang, Qingqing, Liu, Huijuan, Liu, Xiang, Jiang, Dunquan, Zhang, Bingjie, Tian, Hongliang, Yang, Cheng, Guddat, Luke W, Yang, Haitao, Mi, Kaixia, Rao, Zihe, 2018 定量蛋白质组分析蚯蚓血红蛋白样蛋白MSMEG_3312介导的分枝杆菌耐红霉素机制, 张玉娇, 胡新玲, 李晓静, 邓海腾, 米凯霞, 2018 Structural insight into the Zika virus capsid encapsulating the viral genome, Ting Li, Qi Zhao, Xiaoyun Yang, Cheng Chen, Kailin Yang, Chen Wu, Tianqing Zhang, Yinkai Duan, Xiaoyu Xue, Kaixia Mi, Xiaoyun Ji, Zefang Wang, Haitao Yang, 2018 Structural insight into the Zika virus capsid encapsulating the viral genome, Li, Ting, Zhao, Qi, Yang, Xiaoyun, Chen, Cheng, Yang, Kailin, Wu, Chen, Zhang, Tianqing, Duan, Yinkai, Xue, Xiaoyu, Mi, Kaixia, Ji, Xiaoyun, Wang, Zefang, Yang, Haitao, 2018 Structural Insight into the Activation of PknI Kinase from M. tuberculosis via Dimerization of the Extracellular Sensor Domain, Yan, Qiaoling, Jiang, Dunquan, Qian, Lanfang, Zhang, Qingqing, Zhang, Wei, Zhou, Weihong, Mi, Kaixia, Guddat, Luke, Yang, Haitao, Rao, Zihe, 2017 Universal stress protein Rv2624c alters abundance of arginine and enhances intracellular survival by ATP binding in mycobacteria, Jia, Qiong, Hu, Xinling, Shi, Dawei, Zhang, Yan, Sun, Meihao, Wang, Jianwei, Mi, Kaixia, Zhu, Guofeng, 2016 结核分枝杆菌耐氟喹诺酮类药物的分子机制研究进展, 张玉娇, 李晓静, 米凯霞, 2016 Quantitative Proteomics Reveals Novel Insights into Isoniazid Susceptibility in Mycobacteria Mediated by a Universal Stress Protein, Hu, Xinling, Li, Xiaojing, Huang, Lige, Chan, John, Chen, Yuling, Deng, Haiteng, Mi, Kaixia, 2015 Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility, Li, Xiaojing, Li, Jingjing, Hu, Xinling, Huang, Lige, Xiao, Jing, Chan, John, Mi, Kaixia, 2015 A bacterial hemerythrin-like protein MsmHr inhibits the SigF-dependent hydrogen peroxide response in mycobacteria, Li, Xiaojing, Tao, Jun, Hu, Xinling, Chan, John, Xiao, Jing, Mi, Kaixia, 2015 Functional Characterization of Sirtuin-like Protein in Mycobacterium smegmatis, Gu, Lixiao, Chen, Yuling, Wang, Qingtao, Li, Xiaojing, Mi, Kaixia, Deng, Haiteng, 2015 Proteomic Analysis of Drug-Resistant Mycobacteria: Co-Evolution of Copper and INH Resistance, Chen, Yuling, Yang, Fan, Sun, Zhongyuan, Wang, Qingtao, Mi, Kaixia, Deng, Haiteng, 2015 HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions, Zhang, Yanqing, Mandava, Chandra Sekhar, Cao, Wei, Li, Xiaojing, Zhang, Dejiu, Li, Ningning, Zhang, Yiudao, Zhang, Xiaoxiao, Qin, Yan, Mi, Kaixia, Lei, Jianlin, Sanyal, Suparna, Gao, Ning, 2015 Distinct Responses of Mycobacterium smegmatis to Exposure to Low and High Levels of Hydrogen Peroxide, Li, Xiaojing, Wu, Jun, Han, Jiao, Hu, Yongfei, Mi, Kaixia, 2015 耻垢分枝杆菌的蚯蚓血红蛋白MSMEG_3312影响其大环内酯类抗生素的敏感性, 黄鹂歌, 胡新玲, 陶均, 米凯霞, 2014 The gain of hydrogen peroxide resistance benefits growth fitness in mycobacteria under stress, Li, Xiaojing, Tao, Jun, Han, Jiao, Hu, Xinling, Chen, Yuling, Deng, Haiteng, Zhang, Guangchun, Hu, Xiaoxiang, Mi, Kaixia, 2014 定量蛋白质组学分析ClpS在分枝杆菌耐药中的功能, 古丽莎娜阿地里江, 冯杉, 米凯霞, 邓海腾, 2014 Draft Genome Sequence of mc 2 51, a Highly Hydrogen Peroxide-Resistant Mycobacterium smegmatis Mutant Strain, Xiaojing Li, Fei Liu, Yongfei Hu, Kaixia Mi, 2014 定量蛋白质组学分析PknG在分枝杆菌中的功能, 陈宇凌, 江晓勇, 杨帆, 王清涛, 米凯霞, 邓海腾, 2014 耻垢分枝杆菌的蚯蚓血红蛋白样蛋白MSMEG_3312影响其大环内酯类药物的敏感性, 米凯霞, 黄鹂歌, 胡新玲, 陶均, 2014 Mycobacterium fluoroquinolone resistance protein B, a novel small GTPase, is involved in the regulation of DNA gyrase and drug resistance, Tao, Jun, Han, Jiao, Wu, Hanyu, Hu, Xinling, Deng, Jiaoyu, Fleming, Joy, Maxwell, Anthony, Bi, Lijun, Mi, Kaixia, 2013 2011年Keystone Symposium结核病国际会议简介, 米凯霞, 张宗德, 2012 选择性σ因子SigF影响耻垢分枝杆菌的抗氧化能力, 吴寒宇, 胡新玲, 肖璟, 张京阳, 陶均, 黄红兰, 米凯霞, 2012 2011年Keystone Symposium结核病国际会议简介, 张宗德, 米凯霞, 2011 植物口服疫苗的动物和临床实验, 于静, 米凯霞, 秦智伟, 陈晓英, 2003

Areas of Focus

Pathogenic Microorganisms
Latent Infection and Drug Resistance Mechanisms of Mycobacterium tuberculosis

Publications

Trends and challenges of multi-drug resistance in childhood tuberculosis, Zhuang, Zengfang, Sun, Lin, Song, Xiaorui, Zhu, Hanzhao, Li, Lianju, Zhou, Xintong, Mi, Kaixia, 2023
Advances of new drugs bedaquiline and delamanid in the treatment of multi-drug resistant tuberculosis in children, Zhu, Hanzhao, Zhou, Xintong, Zhuang, Zengfang, Li, Lianju, Bi, Jing, Mi, Kaixia, 2023
The impact of global warming on the signature virulence gene, thermolabile hemolysin, of Vibrio parahaemolyticus, Weishan Zhang, Keyu Chen, Mi Kaixia, 2023
Coevolution of furA-Regulated Hyper-Inflammation and Mycobacterial Resistance to Oxidative Killing through Adaptation to Hydrogen Peroxide, Fan, Xin, Zhao, Bei, Zhang, Weishan, Li, Ning, Mi, Kaixia, Wang, Beinan, 2023
Experimental Evolution Reveals Redox State Modulates Mycobacterial Pathogenicity, Jiang, Zheng, Zhuang, Zengfang, Mi, Kaixia, 2022
The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility, Xinling Hu, Xintong Zhou, Tong Yin, Keyu Chen, Yongfei Hu, Baoli Zhu, Kaixia Mi, 2021
新型冠状病毒对冷链运输食品质量安全的影响, 张玮珊, 胡新玲, 律娜, 米凯霞, 2021
后基因组时代诺如病毒的研究进展, 张玮珊, 胡新玲, 律娜, 徐颖华, 米凯霞, 2021
The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic, Feng, Lipeng, Mundy, Julia E A, Stevenson, Clare E M, Mitchenall, Lesley A, Lawson, David M, Mi, Kaixia, Maxwell, Anthony, 2021
结核病和微生物菌群的关系, 裴佳宾, 杨雨媛, 周心童, 胡格, 王雪涵, 郭勇, 米凯霞, 2020
The plasmid-borne quinolone resistance protein QnrB, a novel DnaA-binding protein, increases the bacterial mutation rate by triggering DNA replication stress, Li, Xiaojing, Zhang, Yujiao, Zhou, Xintong, Hu, Xinling, Zhou, Yixuan, Liu, Di, Maxwell, Anthony, Mi, Kaixia, 2019
分枝杆菌丝氨酸/苏氨酸蛋白激酶PknK的功能研究, 周怡璇, 周心童, 杨健, 胡新玲, 米凯霞, 2019
结核病疫苗和耻垢分枝杆菌引起树突状细胞差异免疫反应的蛋白质组学分析, 霍祎, 宗兆运, 米凯霞, 邓海腾, 2018
Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target, Zhang, Qingqing, Liu, Huijuan, Liu, Xiang, Jiang, Dunquan, Zhang, Bingjie, Tian, Hongliang, Yang, Cheng, Guddat, Luke W, Yang, Haitao, Mi, Kaixia, Rao, Zihe, 2018
定量蛋白质组分析蚯蚓血红蛋白样蛋白MSMEG_3312介导的分枝杆菌耐红霉素机制, 张玉娇, 胡新玲, 李晓静, 邓海腾, 米凯霞, 2018
Structural insight into the Zika virus capsid encapsulating the viral genome, Ting Li, Qi Zhao, Xiaoyun Yang, Cheng Chen, Kailin Yang, Chen Wu, Tianqing Zhang, Yinkai Duan, Xiaoyu Xue, Kaixia Mi, Xiaoyun Ji, Zefang Wang, Haitao Yang, 2018
Structural insight into the Zika virus capsid encapsulating the viral genome, Li, Ting, Zhao, Qi, Yang, Xiaoyun, Chen, Cheng, Yang, Kailin, Wu, Chen, Zhang, Tianqing, Duan, Yinkai, Xue, Xiaoyu, Mi, Kaixia, Ji, Xiaoyun, Wang, Zefang, Yang, Haitao, 2018
Structural Insight into the Activation of PknI Kinase from M. tuberculosis via Dimerization of the Extracellular Sensor Domain, Yan, Qiaoling, Jiang, Dunquan, Qian, Lanfang, Zhang, Qingqing, Zhang, Wei, Zhou, Weihong, Mi, Kaixia, Guddat, Luke, Yang, Haitao, Rao, Zihe, 2017
Universal stress protein Rv2624c alters abundance of arginine and enhances intracellular survival by ATP binding in mycobacteria, Jia, Qiong, Hu, Xinling, Shi, Dawei, Zhang, Yan, Sun, Meihao, Wang, Jianwei, Mi, Kaixia, Zhu, Guofeng, 2016
结核分枝杆菌耐氟喹诺酮类药物的分子机制研究进展, 张玉娇, 李晓静, 米凯霞, 2016
Quantitative Proteomics Reveals Novel Insights into Isoniazid Susceptibility in Mycobacteria Mediated by a Universal Stress Protein, Hu, Xinling, Li, Xiaojing, Huang, Lige, Chan, John, Chen, Yuling, Deng, Haiteng, Mi, Kaixia, 2015
Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility, Li, Xiaojing, Li, Jingjing, Hu, Xinling, Huang, Lige, Xiao, Jing, Chan, John, Mi, Kaixia, 2015
A bacterial hemerythrin-like protein MsmHr inhibits the SigF-dependent hydrogen peroxide response in mycobacteria, Li, Xiaojing, Tao, Jun, Hu, Xinling, Chan, John, Xiao, Jing, Mi, Kaixia, 2015
Functional Characterization of Sirtuin-like Protein in Mycobacterium smegmatis, Gu, Lixiao, Chen, Yuling, Wang, Qingtao, Li, Xiaojing, Mi, Kaixia, Deng, Haiteng, 2015
Proteomic Analysis of Drug-Resistant Mycobacteria: Co-Evolution of Copper and INH Resistance, Chen, Yuling, Yang, Fan, Sun, Zhongyuan, Wang, Qingtao, Mi, Kaixia, Deng, Haiteng, 2015
HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions, Zhang, Yanqing, Mandava, Chandra Sekhar, Cao, Wei, Li, Xiaojing, Zhang, Dejiu, Li, Ningning, Zhang, Yiudao, Zhang, Xiaoxiao, Qin, Yan, Mi, Kaixia, Lei, Jianlin, Sanyal, Suparna, Gao, Ning, 2015
Distinct Responses of Mycobacterium smegmatis to Exposure to Low and High Levels of Hydrogen Peroxide, Li, Xiaojing, Wu, Jun, Han, Jiao, Hu, Yongfei, Mi, Kaixia, 2015
耻垢分枝杆菌的蚯蚓血红蛋白MSMEG_3312影响其大环内酯类抗生素的敏感性, 黄鹂歌, 胡新玲, 陶均, 米凯霞, 2014
The gain of hydrogen peroxide resistance benefits growth fitness in mycobacteria under stress, Li, Xiaojing, Tao, Jun, Han, Jiao, Hu, Xinling, Chen, Yuling, Deng, Haiteng, Zhang, Guangchun, Hu, Xiaoxiang, Mi, Kaixia, 2014
定量蛋白质组学分析ClpS在分枝杆菌耐药中的功能, 古丽莎娜阿地里江, 冯杉, 米凯霞, 邓海腾, 2014
Draft Genome Sequence of mc 2 51, a Highly Hydrogen Peroxide-Resistant Mycobacterium smegmatis Mutant Strain, Xiaojing Li, Fei Liu, Yongfei Hu, Kaixia Mi, 2014
定量蛋白质组学分析PknG在分枝杆菌中的功能, 陈宇凌, 江晓勇, 杨帆, 王清涛, 米凯霞, 邓海腾, 2014
耻垢分枝杆菌的蚯蚓血红蛋白样蛋白MSMEG_3312影响其大环内酯类药物的敏感性, 米凯霞, 黄鹂歌, 胡新玲, 陶均, 2014
Mycobacterium fluoroquinolone resistance protein B, a novel small GTPase, is involved in the regulation of DNA gyrase and drug resistance, Tao, Jun, Han, Jiao, Wu, Hanyu, Hu, Xinling, Deng, Jiaoyu, Fleming, Joy, Maxwell, Anthony, Bi, Lijun, Mi, Kaixia, 2013
2011年Keystone Symposium结核病国际会议简介, 米凯霞, 张宗德, 2012
选择性σ因子SigF影响耻垢分枝杆菌的抗氧化能力, 吴寒宇, 胡新玲, 肖璟, 张京阳, 陶均, 黄红兰, 米凯霞, 2012
2011年Keystone Symposium结核病国际会议简介, 张宗德, 米凯霞, 2011
植物口服疫苗的动物和临床实验, 于静, 米凯霞, 秦智伟, 陈晓英, 2003

Pathogenic Microorganisms Mycobacterium Tuberculosis Latent Infection Drug Resistance Molecular Mechanisms Microbiology Pathogenesis Infectious Diseases Bacterial Pathogens Immunology

Kaixia Mi - University of Chinese Academy of Sciences

Min Zhao - Wuhan University

Congrong Li - Wuhan University

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