Kaixia Mi
Medical School
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Contact
Pathogenic Microorganisms Mycobacterium Tuberculosis Latent Infection Drug Resistance Molecular Mechanisms Microbiology Pathogenesis Infectious Diseases Bacterial Pathogens Immunology
Areas of Focus
  • Pathogenic Microorganisms
  • Latent Infection and Drug Resistance Mechanisms of Mycobacterium tuberculosis
Work Experience
  • 2009-present - Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology - Group Leader
  • 2004-2009 - Albert Einstein College of Medicine - Research Assistant
  • 2003-2004 - Texas University Health Science Center San Antonio - Postdoctoral Researcher
Academic Background & Achievements
  • 1999-2003 PhD in Genetics: Institute of Microbiology, Chinese Academy of Sciences
Publications
  • Trends and challenges of multi-drug resistance in childhood tuberculosis, Zhuang, Zengfang, Sun, Lin, Song, Xiaorui, Zhu, Hanzhao, Li, Lianju, Zhou, Xintong, Mi, Kaixia, 2023
  • Advances of new drugs bedaquiline and delamanid in the treatment of multi-drug resistant tuberculosis in children, Zhu, Hanzhao, Zhou, Xintong, Zhuang, Zengfang, Li, Lianju, Bi, Jing, Mi, Kaixia, 2023
  • The impact of global warming on the signature virulence gene, thermolabile hemolysin, of Vibrio parahaemolyticus, Weishan Zhang, Keyu Chen, Mi Kaixia, 2023
  • Coevolution of furA-Regulated Hyper-Inflammation and Mycobacterial Resistance to Oxidative Killing through Adaptation to Hydrogen Peroxide, Fan, Xin, Zhao, Bei, Zhang, Weishan, Li, Ning, Mi, Kaixia, Wang, Beinan, 2023
  • Experimental Evolution Reveals Redox State Modulates Mycobacterial Pathogenicity, Jiang, Zheng, Zhuang, Zengfang, Mi, Kaixia, 2022
  • The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility, Xinling Hu, Xintong Zhou, Tong Yin, Keyu Chen, Yongfei Hu, Baoli Zhu, Kaixia Mi, 2021
  • 新型冠状病毒对冷链运输食品质量安全的影响, 张玮珊, 胡新玲, 律娜, 米凯霞, 2021
  • 后基因组时代诺如病毒的研究进展, 张玮珊, 胡新玲, 律娜, 徐颖华, 米凯霞, 2021
  • The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic, Feng, Lipeng, Mundy, Julia E A, Stevenson, Clare E M, Mitchenall, Lesley A, Lawson, David M, Mi, Kaixia, Maxwell, Anthony, 2021
  • 结核病和微生物菌群的关系, 裴佳宾, 杨雨媛, 周心童, 胡格, 王雪涵, 郭勇, 米凯霞, 2020
  • The plasmid-borne quinolone resistance protein QnrB, a novel DnaA-binding protein, increases the bacterial mutation rate by triggering DNA replication stress, Li, Xiaojing, Zhang, Yujiao, Zhou, Xintong, Hu, Xinling, Zhou, Yixuan, Liu, Di, Maxwell, Anthony, Mi, Kaixia, 2019
  • 分枝杆菌丝氨酸/苏氨酸蛋白激酶PknK的功能研究, 周怡璇, 周心童, 杨健, 胡新玲, 米凯霞, 2019
  • 结核病疫苗和耻垢分枝杆菌引起树突状细胞差异免疫反应的蛋白质组学分析, 霍祎, 宗兆运, 米凯霞, 邓海腾, 2018
  • Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target, Zhang, Qingqing, Liu, Huijuan, Liu, Xiang, Jiang, Dunquan, Zhang, Bingjie, Tian, Hongliang, Yang, Cheng, Guddat, Luke W, Yang, Haitao, Mi, Kaixia, Rao, Zihe, 2018
  • 定量蛋白质组分析蚯蚓血红蛋白样蛋白MSMEG_3312介导的分枝杆菌耐红霉素机制, 张玉娇, 胡新玲, 李晓静, 邓海腾, 米凯霞, 2018
  • Structural insight into the Zika virus capsid encapsulating the viral genome, Ting Li, Qi Zhao, Xiaoyun Yang, Cheng Chen, Kailin Yang, Chen Wu, Tianqing Zhang, Yinkai Duan, Xiaoyu Xue, Kaixia Mi, Xiaoyun Ji, Zefang Wang, Haitao Yang, 2018
  • Structural insight into the Zika virus capsid encapsulating the viral genome, Li, Ting, Zhao, Qi, Yang, Xiaoyun, Chen, Cheng, Yang, Kailin, Wu, Chen, Zhang, Tianqing, Duan, Yinkai, Xue, Xiaoyu, Mi, Kaixia, Ji, Xiaoyun, Wang, Zefang, Yang, Haitao, 2018
  • Structural Insight into the Activation of PknI Kinase from M. tuberculosis via Dimerization of the Extracellular Sensor Domain, Yan, Qiaoling, Jiang, Dunquan, Qian, Lanfang, Zhang, Qingqing, Zhang, Wei, Zhou, Weihong, Mi, Kaixia, Guddat, Luke, Yang, Haitao, Rao, Zihe, 2017
  • Universal stress protein Rv2624c alters abundance of arginine and enhances intracellular survival by ATP binding in mycobacteria, Jia, Qiong, Hu, Xinling, Shi, Dawei, Zhang, Yan, Sun, Meihao, Wang, Jianwei, Mi, Kaixia, Zhu, Guofeng, 2016
  • 结核分枝杆菌耐氟喹诺酮类药物的分子机制研究进展, 张玉娇, 李晓静, 米凯霞, 2016
  • Quantitative Proteomics Reveals Novel Insights into Isoniazid Susceptibility in Mycobacteria Mediated by a Universal Stress Protein, Hu, Xinling, Li, Xiaojing, Huang, Lige, Chan, John, Chen, Yuling, Deng, Haiteng, Mi, Kaixia, 2015
  • Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility, Li, Xiaojing, Li, Jingjing, Hu, Xinling, Huang, Lige, Xiao, Jing, Chan, John, Mi, Kaixia, 2015
  • A bacterial hemerythrin-like protein MsmHr inhibits the SigF-dependent hydrogen peroxide response in mycobacteria, Li, Xiaojing, Tao, Jun, Hu, Xinling, Chan, John, Xiao, Jing, Mi, Kaixia, 2015
  • Functional Characterization of Sirtuin-like Protein in Mycobacterium smegmatis, Gu, Lixiao, Chen, Yuling, Wang, Qingtao, Li, Xiaojing, Mi, Kaixia, Deng, Haiteng, 2015
  • Proteomic Analysis of Drug-Resistant Mycobacteria: Co-Evolution of Copper and INH Resistance, Chen, Yuling, Yang, Fan, Sun, Zhongyuan, Wang, Qingtao, Mi, Kaixia, Deng, Haiteng, 2015
  • HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions, Zhang, Yanqing, Mandava, Chandra Sekhar, Cao, Wei, Li, Xiaojing, Zhang, Dejiu, Li, Ningning, Zhang, Yiudao, Zhang, Xiaoxiao, Qin, Yan, Mi, Kaixia, Lei, Jianlin, Sanyal, Suparna, Gao, Ning, 2015
  • Distinct Responses of Mycobacterium smegmatis to Exposure to Low and High Levels of Hydrogen Peroxide, Li, Xiaojing, Wu, Jun, Han, Jiao, Hu, Yongfei, Mi, Kaixia, 2015
  • 耻垢分枝杆菌的蚯蚓血红蛋白MSMEG_3312影响其大环内酯类抗生素的敏感性, 黄鹂歌, 胡新玲, 陶均, 米凯霞, 2014
  • The gain of hydrogen peroxide resistance benefits growth fitness in mycobacteria under stress, Li, Xiaojing, Tao, Jun, Han, Jiao, Hu, Xinling, Chen, Yuling, Deng, Haiteng, Zhang, Guangchun, Hu, Xiaoxiang, Mi, Kaixia, 2014
  • 定量蛋白质组学分析ClpS在分枝杆菌耐药中的功能, 古丽莎娜阿地里江, 冯杉, 米凯霞, 邓海腾, 2014
  • Draft Genome Sequence of mc 2 51, a Highly Hydrogen Peroxide-Resistant Mycobacterium smegmatis Mutant Strain, Xiaojing Li, Fei Liu, Yongfei Hu, Kaixia Mi, 2014
  • 定量蛋白质组学分析PknG在分枝杆菌中的功能, 陈宇凌, 江晓勇, 杨帆, 王清涛, 米凯霞, 邓海腾, 2014
  • 耻垢分枝杆菌的蚯蚓血红蛋白样蛋白MSMEG_3312影响其大环内酯类药物的敏感性, 米凯霞, 黄鹂歌, 胡新玲, 陶均, 2014
  • Mycobacterium fluoroquinolone resistance protein B, a novel small GTPase, is involved in the regulation of DNA gyrase and drug resistance, Tao, Jun, Han, Jiao, Wu, Hanyu, Hu, Xinling, Deng, Jiaoyu, Fleming, Joy, Maxwell, Anthony, Bi, Lijun, Mi, Kaixia, 2013
  • 2011年Keystone Symposium结核病国际会议简介, 米凯霞, 张宗德, 2012
  • 选择性σ因子SigF影响耻垢分枝杆菌的抗氧化能力, 吴寒宇, 胡新玲, 肖璟, 张京阳, 陶均, 黄红兰, 米凯霞, 2012
  • 2011年Keystone Symposium结核病国际会议简介, 张宗德, 米凯霞, 2011
  • 植物口服疫苗的动物和临床实验, 于静, 米凯霞, 秦智伟, 陈晓英, 2003
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