Professor | Jin Zhong | Asia Growth Partners

Name	Jin Zhong
Contact Information	jzhong@sibs.ac.cn
Language ability	English, Chinese
Province	Shanghai

Name

Jin Zhong

Contact Information

jzhong@sibs.ac.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1997-08--2003-08 Ph.D.: University of Texas 1994-09--1997-07 Master's: Peking University 1990-09--1994-07 Bachelor's: Sichuan University
Work Experience	2016-01~Present - Chinese Academy of Sciences - Distinguished Researcher 2013-01~Present - ShanghaiTech University - Distinguished Professor 2007-01~Present - Shanghai Pasteur Institute, Chinese Academy of Sciences - Researcher, Group Leader, Assistant Director 2003-09~2006-12 - Scripps Research Institute - Postdoctoral Research Assistant
Awards	2015: 'Emergences' Award by the French Embassy in China 2014: Excellent Graduate Student Supervisor Award by the Chinese Academy of Sciences 2013: State Council Special Allowance Expert 2012: Outstanding Young Scientific and Technological Innovation Talent Nomination Award by the Shanghai Branch of the Chinese Academy of Sciences 2012: Zhu Li Yuehua Excellent Teacher Award by the Chinese Academy of Sciences 2010: Outstanding Young Talent by the Chinese Academy of Sciences 2009: French Talent Innovation Award

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1997-08--2003-08 Ph.D.: University of Texas
1994-09--1997-07 Master's: Peking University
1990-09--1994-07 Bachelor's: Sichuan University

Work Experience

2016-01~Present - Chinese Academy of Sciences - Distinguished Researcher
2013-01~Present - ShanghaiTech University - Distinguished Professor
2007-01~Present - Shanghai Pasteur Institute, Chinese Academy of Sciences - Researcher, Group Leader, Assistant Director
2003-09~2006-12 - Scripps Research Institute - Postdoctoral Research Assistant

Awards

2015: 'Emergences' Award by the French Embassy in China
2014: Excellent Graduate Student Supervisor Award by the Chinese Academy of Sciences
2013: State Council Special Allowance Expert
2012: Outstanding Young Scientific and Technological Innovation Talent Nomination Award by the Shanghai Branch of the Chinese Academy of Sciences
2012: Zhu Li Yuehua Excellent Teacher Award by the Chinese Academy of Sciences
2010: Outstanding Young Talent by the Chinese Academy of Sciences
2009: French Talent Innovation Award

Areas of Focus	Virology Immunology Antiviral Drug Screening
Publications	Discovery of a fused bicyclic derivative of 4-hydroxypyrrolidine and imidazolidinone as a new anti-HCV agent, Yifan Xing, Ran Chen, Feng Li, Bin Xu, Lin Han, Chaolun Liu, Yimin Tong, Yaming Jiu, Jin Zhong, GuoChun Zhou, 2023 Construction and characterization of a new hepatitis C virus genotype 6a subgenomic replicon that is prone to render the sofosbuvir resistance, Chaolun Liu, Mingzhe Guo, Lin Han, Jie Lu, Xiaogang Xiang, Qing Xie, Janin Nouhin, Veasna Duong, Yimin Tong, Jin Zhong, 2023 Identification of a novel replication-competent hepatitis C virus variant that confers the sofosbuvir resistance, Leumi, Steve, Guo, Mingzhe, Lu, Jie, Wang, Zhaoning, Gan, Tianyu, Han, Lin, Ngari, Jackline, Tong, Yimin, Xiang, Xiaogang, Xie, Qing, Wang, Lanfeng, Zhong, Jin, 2022 Inhibitor Development against p7 Channel in Hepatitis C Virus, Wei, Shukun, Hu, Xiaoyou, Du, Lingyu, Zhao, Linlin, Xue, Hongjuan, Liu, Chaolun, Chou, James J, Zhong, Jin, Tong, Yimin, Wang, Shuqing, OuYang, Bo, 2021 Photo-catalyzed TiO2 inactivates pathogenic viruses by attacking viral genome, Tong, Yimin, Shi, Gansheng, Hu, Gaowei, Hu, Xiaoyou, Han, Lin, Xie, Xiaofeng, Xu, Yongfen, Zhang, Rong, Sun, Jing, Zhong, Jin, 2021 Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody, Yi, Chunyan, Xia, Jing, He, Lan, Ling, Zhiyang, Wang, Xuesong, Yan, Yu, Wang, Jiangjun, Zhao, Xinhao, Fan, Weiguo, Sun, Xiaoyu, Zhang, Ronghua, Ye, Sheng, Zhang, Rongguang, Xu, Yongfen, Ma, Liyan, Zhang, Yaguang, Zhou, Honglin, Huang, Zhong, Niu, Junqi, Long, Gang, Lu, Junxia, Zhong, Jin, Sun, Bing, 2021 TRIM26 is a critical host factor for HCV replication and contributes to host tropism, Liang, Yisha, Zhang, Guigen, Li, Qiheng, Han, Lin, Hu, Xiaoyou, Guo, Yu, Tao, Wanyin, Zhao, Xiaomin, Guo, Mingzhe, Gan, Tianyu, Tong, Yimin, Xu, Yongfen, Zhou, Zhuo, Ding, Qiang, Wei, Wensheng, Zhong, Jin, 2021 Glycometabolism regulates hepatitis C virus release, Tao Yu, Qiankun Yang, Fangling Tian, Haishuang Chang, Zhenzheng Hu, Bowen Yu, Lin Han, Yifan Xing, Yaming Jiu, Yongning He, Jin Zhong, 2021 Corrigendum to 'DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication' Virology 435 (2013) 385–394, Xi Kang, Xi Chen, Ying He, Deyin Guo, Lin Guo, Jin Zhong, HongBing Shu, 2021 UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation, He, Zhenliang, Ye, Sichao, Xing, Yifan, Jiu, Yaming, Zhong, Jin, 2021 Hepatitis C virus genotype 4: A poorly characterized endemic genotype, Leumi, Steve, El Kassas, Mohamed, Zhong, Jin, 2021 A novel cell culture system modeling the SARS-CoV-2 life cycle, Ju, Xiaohui, Zhu, Yunkai, Wang, Yuyan, Li, Jingrui, Zhang, Jiaxing, Gong, Mingli, Ren, Wenlin, Li, Sai, Zhong, Jin, Zhang, Linqi, Zhang, Qiangfeng Cliff, Zhang, Rong, Ding, Qiang, 2021 Development of a New Reverse Genetics System for Ebola Virus, Tianyu Gan, Dihan Zhou, Yi Huang, Shuqi Xiao, Ziyue Ma, Xiaoyou Hu, Yimin Tong, Huimin Yan, Jin Zhong, 2021 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals, Xu, Xin, Peng, Ruchao, Peng, Qi, Wang, Min, Xu, Ying, Liu, Sheng, Tian, Xiaolin, Deng, Haiteng, Tong, Yimin, Hu, Xiaoyou, Zhong, Jin, Wang, Peiyi, Qi, Jianxun, Gao, George F, Shi, Yi, 2021 DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication (vol 435, pg 385, 2013), Kang, Xi, Chen, Xi, He, Ying, Guo, Deyin, Guo, Lin, Zhong, Jin, Shu, HongBing, 2021 Anti-flavivirus activity of polyoxometalate, Qi, Yue, Han, Lin, Qi, Yanfei, Jin, Xia, Zhang, Bo, Niu, Junqi, Zhong, Jin, Xu, Yongfen, 2020 关于新型冠状病毒命名的思考与建议, 张冬梅, 姜世勃, 石正丽, 谭文杰, 卢洪洲, 曹彬, 张文宏, 刘叔文, 钟劲, 肖庚富, 谢幼华, 邓凯, 赵金存, 杨子峰, 宋敬东, 陆路, 黄竞荷, 应天雷, 王乔, 施莽, 徐建青, 安静, 鲁凤民, 高福, 舒跃龙, 郭德银, 2020 Small Molecule Inhibitor of ATPase Activity of HSP70 as a Broad-Spectrum Inhibitor against Flavivirus Infections, Yang, Jingjing, Xu, Yongfen, Yan, Yunzheng, Li, Wei, Zhao, Lei, Dai, Qingsong, Li, Yuexiang, Li, Song, Zhong, Jin, Cao, Ruiyuan, Zhong, Wu, 2020 IL-1β enhances anti-viral effect of IFN-α on HCV replication by negatively modulating ERK2 activation, Zhong Jing, 2020 2020年度诺奖解读, 谢磊, 钟劲, 2020 A Nanoparticle-Based Hepatitis C Virus Vaccine With Enhanced Potency, Yan, Yu, Wang, Xuesong, Lou, Peilan, Hu, Zhenzheng, Qu, Panke, Li, Dapeng, Li, Qingchao, Xu, Yongfen, Niu, Junqi, He, Yongning, Zhong, Jin, Zhong, Huang, 2020 分子生物学技术推进丙型肝炎病毒的发现和研究——2020年诺贝尔生理学或医学奖解读, 李庆超, 钟劲, 2020 An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, Xu, Ling, Yu, Dandan, Peng, Li, Wu, Yong, Fan, Yu, Gu, Tianle, Yao, YuLin, Zhong, Jin, Chen, Xinwen, Yao, YongGang, 2020 Discovery and research of hepatitis C virus-Thoughts from the 2020 Nobel Prize in Physiology or Medicine, Xu, Yongfen, Long, Gang, Zhong, Jin, 2020 Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, Xu, Ling, Yu, Dandan, Yao, YuLin, Gu, Tianle, Zheng, Xiao, Wu, Yong, Luo, RongHua, Zheng, YongTang, Zhong, Jin, Yao, YongGang, 2020 A novel approach to display structural proteins of HCV quasispecies in patients reveals a key role of E2 HVR1 in viral evolution, Zhong Jing, 2020 丙型肝炎病毒的发现及研究——从2020年度诺贝尔生理学或医学奖谈起, 徐咏芬, 龙钢, 钟劲, 2020 Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections, Xing, Yifan, Wen, Zeyu, Gao, Wei, Lin, Zhekai

Areas of Focus

Virology
Immunology
Antiviral Drug Screening

Publications

Discovery of a fused bicyclic derivative of 4-hydroxypyrrolidine and imidazolidinone as a new anti-HCV agent, Yifan Xing, Ran Chen, Feng Li, Bin Xu, Lin Han, Chaolun Liu, Yimin Tong, Yaming Jiu, Jin Zhong, GuoChun Zhou, 2023
Construction and characterization of a new hepatitis C virus genotype 6a subgenomic replicon that is prone to render the sofosbuvir resistance, Chaolun Liu, Mingzhe Guo, Lin Han, Jie Lu, Xiaogang Xiang, Qing Xie, Janin Nouhin, Veasna Duong, Yimin Tong, Jin Zhong, 2023
Identification of a novel replication-competent hepatitis C virus variant that confers the sofosbuvir resistance, Leumi, Steve, Guo, Mingzhe, Lu, Jie, Wang, Zhaoning, Gan, Tianyu, Han, Lin, Ngari, Jackline, Tong, Yimin, Xiang, Xiaogang, Xie, Qing, Wang, Lanfeng, Zhong, Jin, 2022
Inhibitor Development against p7 Channel in Hepatitis C Virus, Wei, Shukun, Hu, Xiaoyou, Du, Lingyu, Zhao, Linlin, Xue, Hongjuan, Liu, Chaolun, Chou, James J, Zhong, Jin, Tong, Yimin, Wang, Shuqing, OuYang, Bo, 2021
Photo-catalyzed TiO2 inactivates pathogenic viruses by attacking viral genome, Tong, Yimin, Shi, Gansheng, Hu, Gaowei, Hu, Xiaoyou, Han, Lin, Xie, Xiaofeng, Xu, Yongfen, Zhang, Rong, Sun, Jing, Zhong, Jin, 2021
Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody, Yi, Chunyan, Xia, Jing, He, Lan, Ling, Zhiyang, Wang, Xuesong, Yan, Yu, Wang, Jiangjun, Zhao, Xinhao, Fan, Weiguo, Sun, Xiaoyu, Zhang, Ronghua, Ye, Sheng, Zhang, Rongguang, Xu, Yongfen, Ma, Liyan, Zhang, Yaguang, Zhou, Honglin, Huang, Zhong, Niu, Junqi, Long, Gang, Lu, Junxia, Zhong, Jin, Sun, Bing, 2021
TRIM26 is a critical host factor for HCV replication and contributes to host tropism, Liang, Yisha, Zhang, Guigen, Li, Qiheng, Han, Lin, Hu, Xiaoyou, Guo, Yu, Tao, Wanyin, Zhao, Xiaomin, Guo, Mingzhe, Gan, Tianyu, Tong, Yimin, Xu, Yongfen, Zhou, Zhuo, Ding, Qiang, Wei, Wensheng, Zhong, Jin, 2021
Glycometabolism regulates hepatitis C virus release, Tao Yu, Qiankun Yang, Fangling Tian, Haishuang Chang, Zhenzheng Hu, Bowen Yu, Lin Han, Yifan Xing, Yaming Jiu, Yongning He, Jin Zhong, 2021
Corrigendum to 'DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication' Virology 435 (2013) 385–394, Xi Kang, Xi Chen, Ying He, Deyin Guo, Lin Guo, Jin Zhong, HongBing Shu, 2021
UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation, He, Zhenliang, Ye, Sichao, Xing, Yifan, Jiu, Yaming, Zhong, Jin, 2021
Hepatitis C virus genotype 4: A poorly characterized endemic genotype, Leumi, Steve, El Kassas, Mohamed, Zhong, Jin, 2021
A novel cell culture system modeling the SARS-CoV-2 life cycle, Ju, Xiaohui, Zhu, Yunkai, Wang, Yuyan, Li, Jingrui, Zhang, Jiaxing, Gong, Mingli, Ren, Wenlin, Li, Sai, Zhong, Jin, Zhang, Linqi, Zhang, Qiangfeng Cliff, Zhang, Rong, Ding, Qiang, 2021
Development of a New Reverse Genetics System for Ebola Virus, Tianyu Gan, Dihan Zhou, Yi Huang, Shuqi Xiao, Ziyue Ma, Xiaoyou Hu, Yimin Tong, Huimin Yan, Jin Zhong, 2021
Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals, Xu, Xin, Peng, Ruchao, Peng, Qi, Wang, Min, Xu, Ying, Liu, Sheng, Tian, Xiaolin, Deng, Haiteng, Tong, Yimin, Hu, Xiaoyou, Zhong, Jin, Wang, Peiyi, Qi, Jianxun, Gao, George F, Shi, Yi, 2021
DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication (vol 435, pg 385, 2013), Kang, Xi, Chen, Xi, He, Ying, Guo, Deyin, Guo, Lin, Zhong, Jin, Shu, HongBing, 2021
Anti-flavivirus activity of polyoxometalate, Qi, Yue, Han, Lin, Qi, Yanfei, Jin, Xia, Zhang, Bo, Niu, Junqi, Zhong, Jin, Xu, Yongfen, 2020
关于新型冠状病毒命名的思考与建议, 张冬梅, 姜世勃, 石正丽, 谭文杰, 卢洪洲, 曹彬, 张文宏, 刘叔文, 钟劲, 肖庚富, 谢幼华, 邓凯, 赵金存, 杨子峰, 宋敬东, 陆路, 黄竞荷, 应天雷, 王乔, 施莽, 徐建青, 安静, 鲁凤民, 高福, 舒跃龙, 郭德银, 2020
Small Molecule Inhibitor of ATPase Activity of HSP70 as a Broad-Spectrum Inhibitor against Flavivirus Infections, Yang, Jingjing, Xu, Yongfen, Yan, Yunzheng, Li, Wei, Zhao, Lei, Dai, Qingsong, Li, Yuexiang, Li, Song, Zhong, Jin, Cao, Ruiyuan, Zhong, Wu, 2020
IL-1β enhances anti-viral effect of IFN-α on HCV replication by negatively modulating ERK2 activation, Zhong Jing, 2020
2020年度诺奖解读, 谢磊, 钟劲, 2020
A Nanoparticle-Based Hepatitis C Virus Vaccine With Enhanced Potency, Yan, Yu, Wang, Xuesong, Lou, Peilan, Hu, Zhenzheng, Qu, Panke, Li, Dapeng, Li, Qingchao, Xu, Yongfen, Niu, Junqi, He, Yongning, Zhong, Jin, Zhong, Huang, 2020
分子生物学技术推进丙型肝炎病毒的发现和研究——2020年诺贝尔生理学或医学奖解读, 李庆超, 钟劲, 2020
An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, Xu, Ling, Yu, Dandan, Peng, Li, Wu, Yong, Fan, Yu, Gu, Tianle, Yao, YuLin, Zhong, Jin, Chen, Xinwen, Yao, YongGang, 2020
Discovery and research of hepatitis C virus-Thoughts from the 2020 Nobel Prize in Physiology or Medicine, Xu, Yongfen, Long, Gang, Zhong, Jin, 2020
Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, Xu, Ling, Yu, Dandan, Yao, YuLin, Gu, Tianle, Zheng, Xiao, Wu, Yong, Luo, RongHua, Zheng, YongTang, Zhong, Jin, Yao, YongGang, 2020
A novel approach to display structural proteins of HCV quasispecies in patients reveals a key role of E2 HVR1 in viral evolution, Zhong Jing, 2020
丙型肝炎病毒的发现及研究——从2020年度诺贝尔生理学或医学奖谈起, 徐咏芬, 龙钢, 钟劲, 2020
Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections, Xing, Yifan, Wen, Zeyu, Gao, Wei, Lin, Zhekai

Hcv Hepatitis C Virology Immunology Antiviral Drug Screening Virus-Host Interaction Cell Culture Model Molecular Mechanism Therapeutics

Hongbing Shu - Wuhan University

Hai-Rong Xiong - Wuhan University

Lifeng Fu - University of Chinese Academy of Sciences

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