Areas of Focus
- Systematic separation of RNA-binding proteins and the study of RNA-protein interactions in cell fate, pathology, and physiological regulation
Work Experience
- 2018-01~Present - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Researcher
- 2013-01~2017-12 - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Associate Researcher
- 2011-07~2012-12 - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2006-09--2011-06 PhD: University of Science and Technology of China
- 2002-09--2006-06 Bachelor's: Anhui University
Publications
- Transcriptome-wide identification of single-stranded RNA binding proteins, Zhao, Ruiqi, Fang, Xin, Mai, Zhibiao, Chen, Xi, Mo, Jing, Lin, Yingying, Xiao, Rui, Bao, Xichen, Weng, Xiaocheng, Zhou, Xiang, 2023
- Application of nucleoside or nucleotide analogues in RNA dynamics and RNA-binding protein analysis, Meifeng Zheng, Yingying Lin, Wei Wang, Yu Zhao, Xichen Bao, 2022
- Capture of the newly transcribed RNA interactome using click chemistry, Guo, Xiangpeng, Tariq, Muqddas, Lai, Yiwei, Kanwal, Shahzina, Lv, Yuan, Wang, Xiwei, Li, Na, Jiang, Mengling, Meng, Jin, Hu, Jieyi, Yuan, Jianwen, Luo, Zhiwei, Ward, Carl, Volpe, Giacomo, Wang, Dongye, Yin, Menghui, Qin, Baoming, Zhang, Biliang, Bao, Xichen, Esteban, Miguel A., 2021
- The RNA m(6)A reader YTHDC1 silences retrotransposons and guards ES cell identity, Liu, Jiadong, Gao, Mingwei, He, Jiangping, Wu, Kaixin, Lin, Siyuan, Jin, Lingmei, Chen, Yaping, Liu, He, Shi, Junjie, Wang, Xiwei, Chang, Lei, Lin, Yingying, Zhao, YuLi, Zhang, Xiaofei, Zhang, Man, Luo, GuanZheng, Wu, Guangming, Pei, Duanqing, Wang, Jie, Bao, Xichen, Chen, Jiekai, 2021
- Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2, Hou, Linlin, Wei, Yuanjie, Lin, Yingying, Wang, Xiwei, Lai, Yiwei, Yin, Menghui, Chen, Yanpu, Guo, Xiangpeng, Wu, Senbin, Zhu, Yindi, Yuan, Jie, Tariq, Muqddas, Li, Na, Sun, Hao, Wang, Huating, Zhang, Xiaofei, Chen, Jiekai, Bao, Xichen, Jauch, Ralf, 2020
- beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus, Zhang, Meng, Lai, Yiwei, Krupalnik, Vladislav, Guo, Pengcheng, Guo, Xiangpeng, Zhou, Jianguo, Xu, Yan, Yu, Zhijun, Liu, Longqi, Jiang, Ao, Li, Wenjuan, Ma, Gang, Li, Na, Fu, Xiuling, Lv, Yuan, Jiang, Mengling, Tariq, Muqddas, Kanwal, Shahzina, Liu, Hao, Xu, Xueting, Zhang, Hui, Huang, Yinghua, Wang, Lulu, Chen, Shuhan, Babarinde, Isaac A, Luo, Zhiwei, Wang, Dongye, Zhou, Tiantian, Ward, Carl, He, Minghui, Ibanez, David P, Li, Yunpan, Zhou, Jiajian, Yuan, Jie, Feng, Yayan, Arumugam, Karthik, Di Vicino, Umberto, Bao, Xichen, Wu, Guangming, Schambach, Axel, Wang, Huating, Sun, Hao, Gao, Fei, Qin, Baoming, Hutchins, Andrew P, Doble, Bradley W, Hartmann, Christine, Cosma, Maria Pia, Qin, Yan, Xu, GuoLiang, Chen, Runsheng, Volpe, Giacomo, Chen, Liang, Hanna, Jacob H, Esteban, Miguel A., 2020
- JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency, Yinghua Huang, Hui Zhang, Lulu Wang, Chuanqing Tang, Xiaogan Qin, Xinyu Wu, Meifang Pan, Yujia Tang, Zhongzhou Yang, Isaac A Babarinde, Runxia Lin, Guanyu Ji, Yiwei Lai, Xueting Xu, Jianbin Su, Xue Wen, Takashi Satoh, Tanveer Ahmed, Vikas Malik, Carl Ward, Giacomo Volpe, Lin Guo, Jinlong Chen, Li Sun, Yingying Li, Xiaofen Huang, Xichen Bao, Fei Gao, Baohua Liu, Hui Zheng, Ralf Jauch, Liangxue Lai, Guangjin Pan, Jiekai Chen, Giuseppe Testa, Shizuo Akira, Jifan Hu, Duanqing Pei, Andrew P Hutchins, Miguel A Esteban, Baoming Qin, 2020
- Identification of mecciRNAs and their roles in the mitochondrial entry of proteins, Liu, Xu, Wang, Xiaolin, Li, Jingxin, Hu, Shanshan, Deng, Yuqi, Yin, Hao, Bao, Xichen, Zhang, Qiangfeng Cliff, Wang, Geng, Wang, Baolong, Shi, Qinghua, Shan, Ge, 2020
- YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways, Liu, Jiadong, Gao, Mingwei, Xu, Shuyang, Chen, Yaping, Wu, Kaixin, Liu, He, Wang, Jie, Yang, Xuejie, Wang, Junwei, Liu, Weiwei, Bao, Xichen, Chen, Jiekai, 2020
- Role of Long Non-coding RNAs in Reprogramming to Induced Pluripotency, Kanwal, Shahzina, Guo, Xiangpeng, Ward, Carl, Volpe, Giacomo, Qin, Baoming, Esteban, Miguel A, Bao, Xichen, 2020
- MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation, Yu Zhao, Jiajian Zhou, Liangqiang He, Yuying Li, Jie Yuan, Kun Sun, Xiaona Chen, Xichen Bao, Miguel A Esteban, Hao Sun, Huating Wang, 2019
- A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes, Yang, Jiayin, Wong, LaiYung, Tian, XiaoYu, Wei, Rui, Lai, WingHon, Au, KaWing, Luo, Zhiwei, Ward, Carl, Ho, WaiIn, Ibanez, David P, Liu, Hao, Bao, Xichen, Qin, Baoming, Huang, Yu, Esteban, Miguel A, Tse, HungFat, 2018
- Capturing the interactome of newly transcribed RNA, Bao, Xichen, Guo, Xiangpeng, Yin, Menghui, Tariq, Muqddas, Lai, Yiwei, Kanwal, Shahzina, Zhou, Jiajian, Li, Na, Lv, Yuan, PulidoQuetglas, Carlos, Wang, Xiwei, Ji, Lu, Khan, Muhammad J, Zhu, Xihua, Luo, Zhiwei, Shao, Changwei, Lim, DoHwan, Liu, Xiao, Li, Nan, Wang, Wei, He, Minghui, Liu, YuLin, Ward, Carl, Wang, Tong, Zhang, Gong, Wang, Dongye, Yang, Jianhua, Chen, Yiwen, Zhang, Chaolin, Jauch, Ralf, Yang, YunGui, Wang, Yangming, Qin, Baoming, Anko, MinnaLiisa, Hutchins, Andrew P, Sun, Hao, Wang, Huating, Fu, XiangDong, Zhang, Biliang, Esteban, Miguel A., 2018
- NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming, Zhuang, Qiang, Li, Wenjuan, Benda, Christina, Huang, Zhijian, Ahmed, Tanveer, Liu, Ping, Guo, Xiangpeng, Ibanez, David P, Luo, Zhiwei, Zhang, Meng, Abdul, Mazid Md, Yang, Zhongzhou, Yang, Jiayin, Huang, Yinghua, Zhang, Hui, Huang, Dehao, Zhou, Jianguo, Zhong, Xiaofen, Zhu, Xihua, Fu, Xiuling, Fan, Wenxia, Liu, Yulin, Xu, Yan, Ward, Carl, Khan, Muhammad Jadoon, Kanwal, Shahzina, Mirza, Bushra, Tortorella, Micky D, Tse, HungFat, Chen, Jiayu, Qin, Baoming, Bao, Xichen, Gao, Shaorong, Hutchins, Andrew P, Esteban, Miguel A., 2018
- A DGCR8-Independent Stable MicroRNA Expression Strategy Reveals Important Functions of miR-290 and miR-183-182 Families in Mouse Embryonic Stem Cells, Wang, XiWen, Hao, Jing, Guo, WenTing, Liao, LeQi, Huang, SiYue, Guo, Xiangpeng, Bao, Xichen, Esteban, Miguel A, Wang, Yangming, 2017
- Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells, Yang, Jiayin, Wang, Yu, Zhou, Ting, Wong, LaiYung, Tian, XiaoYu, Hong, Xueyu, Lai, WingHon, Au, KaWing, Wei, Rui, Liu, Yuqing, Cheng, LaiHung, Liang, Guichan, Huang, Zhijian, Fan, Wenxia, Zhao, Ping, Wang, Xiwei, Ibanez, David P, Luo, Zhiwei, Li, Yingying, Zhong, Xiaofen, Chen, Shuhan, Wang, Dongye, Li, Li, Lai, Liangxue, Qin, Baoming, Bao, Xichen, Hutchins, Andrew P, Siu, ChungWah, Huang, Yu, Esteban, Miguel A, Tse, HungFat, 2017
- Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1, Li, Li, Zhang, Quanjun, Yang, Huaqiang, Zou, Qingjian, Lai, Chengdan, Jiang, Fei, Zhao, Ping, Luo, Zhiwei, Yang, Jiayin, Chen, Qian, Wang, Yan, Newsome, Philip N, Frampton, Jon, Maxwell, Patrick H, Li, Wenjuan, Chen, Shuhan, Wang, Dongye, Siu, TakShing, Tam, Sidney, Tse, HungFat, Qin, Baoming, Bao, Xichen, Esteban, Miguel A, Lai, Liangxue
Awards
- Outstanding Member of the Youth Innovation Promotion Association, Chinese Academy of Sciences (2019)
- Guangdong Outstanding Youth (2019)
- First Prize for Urine-Induced Pluripotent Stem Cell Technology and Somatic Cell Reprogramming Mechanism (2019)
- Guangzhou Pearl River Science and Technology New Star (2016)
- First Prize for Research on Mesenchymal-Epithelial Transition Process in iPS Cell Induction (2015)
