Professor | Xiao Ding | Asia Growth Partners

Name	Xiao Ding
Contact Information	dingxiao@mail.kib.ac.cn
Language ability	Chinese, English
Province	Yunnan

Name

Xiao Ding

Contact Information

dingxiao@mail.kib.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2009-09--2012-12 PhD in Agriculture: Fujian Agriculture and Forestry University 2006-09--2009-01 Master's in Engineering: Huaqiao University 2002-09--2006-06 Bachelor's in Engineering: Huaqiao University
Work Experience	2022-02~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher 2017-02~2022-01 - Kunming Institute of Botany, Chinese Academy of Sciences - Assistant Researcher 2013-10~2017-01 - Kunming Institute of Botany, Chinese Academy of Sciences - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2009-09--2012-12 PhD in Agriculture: Fujian Agriculture and Forestry University
2006-09--2009-01 Master's in Engineering: Huaqiao University
2002-09--2006-06 Bachelor's in Engineering: Huaqiao University

Work Experience

2022-02~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
2017-02~2022-01 - Kunming Institute of Botany, Chinese Academy of Sciences - Assistant Researcher
2013-10~2017-01 - Kunming Institute of Botany, Chinese Academy of Sciences - Postdoctoral Researcher

Areas of Focus	Chemical Biology Natural Medicinal Chemistry
Publications	Acetylcholinesterase inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta, Jinliang Li, Fengchao Li, Guoxing Wu, Furong Gui, Hongmei Li, Lili Xu, Xiaojiang Hao, Yuhan Zhao, Xiao Ding, Xiaoping Qin, 2023 Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health, Cui, JinJin, Li, Rui, Ma, XiaoLei, Yu, HaoYang, Luo, ZhiGang, Du, Peng, Ren, Ling, Ding, Xiao, Guo, XiuPing, Zheng, WenSheng, Jiang, JianDong, Che, Yongsheng, Wang, LuLu, 2023 Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut–brain axis, HuiHui Guo, HaoRan Shen, MingZe Tang, Ning Sheng, Xiao Ding, Yuan Lin, JinLan Zhang, JianDong Jiang, TianLe Gao, LuLu Wang, YanXing Han, 2023 Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress, Zhenpeng Niu, Guihua Tang, Xuenan Wang, Xu Yang, Yueqin Zhao, Yinyuan Wang, Qin Liu, Fan Zhang, Yuhan Zhao, Xiao Ding, Xiaojiang Hao, 2023 Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2, Wang, YiTing, Long, XinYan, Ding, Xiao, Fan, ShiRui, Cai, JieYun, Yang, BiJuan, Zhang, XinFang, Luo, Ronghua, Yang, Lian, Ruan, Ting, Ren, Juan, Jing, ChenXu, Zheng, YongTang, Hao, XiaoJiang, Chen, DuoZhi, 2022 Identification of limonoids from Walsura yunnanensis and evaluation of their cytotoxicity against cancer cell lines, Zhao, Yueqin, Yang, Xu, Fei, Jimin, Dong, Xianxiang, Wang, Yinyuan, Yang, Shan, Hao, Xiaojiang, Ding, Xiao, Zhao, Yuhan, 2022 Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa, Yu, Hang, Li, Jinliang, Wu, Guoxing, Tang, Qingbo, Duan, Xiuan, Liu, Quanjun, Lan, Mingxian, Zhao, Yuhan, Hao, Xiaojiang, Qin, Xiaoping, Ding, Xiao, 2022 Sesquiterpene lactones from Carpesium abrotanoides L. and their activity in inducing protective autophagy, Yang, BaoJia, Wang, Juan, Zeng, ZhengQuan, Yang, Xu, Huang, AiYing, Hao, XiaoJiang, Ding, Xiao, Li, ShunLin, 2022 Nematicidal activity of tirotundin and parthenolide isolated from Tithonia diversifolia and Chrysanthemum parthenium, Lan, Mingxian, Gao, Xi, Duan, Xiuan, Li, Hongmei, Yu, Hang, Li, Jinliang, Zhao, Yueqin, Hao, Xiaojiang, Zhao, Yuhan, Ding, Xiao, Wu, Guoxing, 2022 Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway, Chen, YanNi, Ding, Xiao, Li, DongMei, Sun, Mao, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2021 Ten new nortriterpenes from Euphorbia resinifera and their anti-tomato yellow leaf curl virus activities, Zhao, NingDong, Li, YuLin, Song, Yu, Yang, BaoJia, Ding, Xiao, Gao, Fang, Ye, Jian, Hao, XiaoJiang, Zhang, Yu, Li, ShunLin, 2021 Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells, Wei, Ruiran, Zhao, Yueqin, Wang, Juan, Yang, Xu, Li, Shunlin, Wang, Yinyuan, Yang, Xingzhi, Fei, Jimin, Hao, Xiaojiang, Zhao, Yuhan, Gui, Liming, Ding, Xiao, 2021 Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea, Chen, Chen, Ding, Xiao, Han, Lingling, Zhu, Wentao, Huang, Kepu, Hao, Xiaojiang, Zhang, Yu, 2021 Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway, YanNi Chen, Xiao Ding, DongMei Li, QingYun Lu, Shuai Liu, YingYao Li, YingTong Di, Xin Fang, XiaoJiang Hao, 2021 Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling, Wang, Yajie, Tan, Jiabin, Hu, Peng, Pei, Qiang, Wen, Yan, Ma, Wenqing, Shi, Keqian, Li, Zengzheng, Li, Huiyuan, Cheng, Fengyu, Gu, Xuezhong, Yao, Xiangmei, Man, Yan, Zhao, Renbin, Feng, Shuai, Ding, Xiao, Yang, Tonghua, 2021 Voacafrines A-N, aspidosperma-type monoterpenoid indole alkaloids from Voacanga africana with AChE inhibitory activity, Zhao, Qian, Zhu, WenTao, Ding, Xiao, Huo, ZongQing, Donkor, Paul O, Adelakun, Tiwalade A, Hao, XiaoJiang, Zhang, Yu, 2021 Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification, Zhang, Yu, Ding, Xiao, Yuan, YuXi, Guo, LingLi, Hao, XiaoJiang, 2020 Acotarines A-G, new diterpenoid alkaloids from Aconitum taronense induce lysosomal biogenesis, Si, Yu, Ding, Xiao, Adelakuna, Tiwalade A, Zhang, Yu, Hao, XiaoJiang, 2020 Inhibitory activities of flavonoids from Eupatorium adenophorum against acetylcholinesterase, Li, Mengyue, Gao, Xi, Lan, Mingxian, Liao, Xianbin, Su, Fawu, Fan, Liming, Zhao, Yuhan, Hao, Xiaojiang, Wu, Guoxing, Ding, Xiao, 2020 Tabernaesines A-I, Cytotoxic Aspidosperma-Aspidosperma-Type Bisindole Alkaloids from Tabernaemontana pachysiphon, Yi, WenFang, Ding, Xiao, Chen, YuanZhi, Adelakun, Tiwalade A, Zhang, Yu, Hao, XiaoJiang, 2020 A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud, Adelakun, Tiwalade A, Ding, Xiao, Ombati, Rose M, Zhao, NingDong, ObodozieOfoegbu, Obiageri, Di, YingTong, Zhang, Yu, Hao, XiaoJiang, 2020 Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis, Chen, YanNi, Ding, Xiao, Lu, QingYun, Li, DongMei, Li, BoTing, Liu, Shuai, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2020 12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata, Gui, PengYan, Yan, XiaoHui, Yuan, WenJuan, Ma, YuanLiang, Ding, Xiao, Liu, Shuai, Di, YingTong, Zhu, WeiMing, Hao, XiaoJiang, 2019 Two New C21 Steroidal Glycosides from the Roots of Cynanchum paniculatum, HaiLi Yu, Qin Long, WenFang Yi, BaoJia Yang, Yu Song, Xiao Ding, ShunLin Li, XiaoJiang Hao, 2019 Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis, Zhang, Yu, Ding, Xiao, Shao, Shun, Guo, LingLi, Zhao, Qing, Hao, XiaoJiang, He, HongPing, 2019 Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense, Duan, XiaoXiang, Qin, Dan, Song, HongChuan, Gao, TianCong, Zuo, ShiHao, Yan, Xiao, Wang, JunQi, Ding, Xiao, Di, YingTong, Dong, JinYan, 2019 Abietane Diterpernoids from the Roots of Euphorbia ebracteolata, YuanLiang Ma, XiaoHan Tang, WenJuan Yuan, Xiao Ding, YingTong Di, XiaoJiang Hao, 2018 Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus, Yi, Wenfang, Chen, Duozhi, Ding, Xiao, Li, Xiaonian, Li, Shunlin, Di, Yingtong, Zhang, Yu, Hao, Xiaojiang, 2018 C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death, Li, Yang, Zhang, Yu, Gan, Qiwen, Xu, Meng, Ding, Xiao, Tang, Guihua, Liang, Jingjing, Liu, Kai, Liu, Xuezhao, Wang, Xin, Guo, Lingli, Gao, Zhiyang, Hao, Xiaojiang, Yang, Chonglin, 2018

Areas of Focus

Chemical Biology
Natural Medicinal Chemistry

Publications

Acetylcholinesterase inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta, Jinliang Li, Fengchao Li, Guoxing Wu, Furong Gui, Hongmei Li, Lili Xu, Xiaojiang Hao, Yuhan Zhao, Xiao Ding, Xiaoping Qin, 2023
Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health, Cui, JinJin, Li, Rui, Ma, XiaoLei, Yu, HaoYang, Luo, ZhiGang, Du, Peng, Ren, Ling, Ding, Xiao, Guo, XiuPing, Zheng, WenSheng, Jiang, JianDong, Che, Yongsheng, Wang, LuLu, 2023
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut–brain axis, HuiHui Guo, HaoRan Shen, MingZe Tang, Ning Sheng, Xiao Ding, Yuan Lin, JinLan Zhang, JianDong Jiang, TianLe Gao, LuLu Wang, YanXing Han, 2023
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress, Zhenpeng Niu, Guihua Tang, Xuenan Wang, Xu Yang, Yueqin Zhao, Yinyuan Wang, Qin Liu, Fan Zhang, Yuhan Zhao, Xiao Ding, Xiaojiang Hao, 2023
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2, Wang, YiTing, Long, XinYan, Ding, Xiao, Fan, ShiRui, Cai, JieYun, Yang, BiJuan, Zhang, XinFang, Luo, Ronghua, Yang, Lian, Ruan, Ting, Ren, Juan, Jing, ChenXu, Zheng, YongTang, Hao, XiaoJiang, Chen, DuoZhi, 2022
Identification of limonoids from Walsura yunnanensis and evaluation of their cytotoxicity against cancer cell lines, Zhao, Yueqin, Yang, Xu, Fei, Jimin, Dong, Xianxiang, Wang, Yinyuan, Yang, Shan, Hao, Xiaojiang, Ding, Xiao, Zhao, Yuhan, 2022
Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa, Yu, Hang, Li, Jinliang, Wu, Guoxing, Tang, Qingbo, Duan, Xiuan, Liu, Quanjun, Lan, Mingxian, Zhao, Yuhan, Hao, Xiaojiang, Qin, Xiaoping, Ding, Xiao, 2022
Sesquiterpene lactones from Carpesium abrotanoides L. and their activity in inducing protective autophagy, Yang, BaoJia, Wang, Juan, Zeng, ZhengQuan, Yang, Xu, Huang, AiYing, Hao, XiaoJiang, Ding, Xiao, Li, ShunLin, 2022
Nematicidal activity of tirotundin and parthenolide isolated from Tithonia diversifolia and Chrysanthemum parthenium, Lan, Mingxian, Gao, Xi, Duan, Xiuan, Li, Hongmei, Yu, Hang, Li, Jinliang, Zhao, Yueqin, Hao, Xiaojiang, Zhao, Yuhan, Ding, Xiao, Wu, Guoxing, 2022
Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway, Chen, YanNi, Ding, Xiao, Li, DongMei, Sun, Mao, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2021
Ten new nortriterpenes from Euphorbia resinifera and their anti-tomato yellow leaf curl virus activities, Zhao, NingDong, Li, YuLin, Song, Yu, Yang, BaoJia, Ding, Xiao, Gao, Fang, Ye, Jian, Hao, XiaoJiang, Zhang, Yu, Li, ShunLin, 2021
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells, Wei, Ruiran, Zhao, Yueqin, Wang, Juan, Yang, Xu, Li, Shunlin, Wang, Yinyuan, Yang, Xingzhi, Fei, Jimin, Hao, Xiaojiang, Zhao, Yuhan, Gui, Liming, Ding, Xiao, 2021
Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea, Chen, Chen, Ding, Xiao, Han, Lingling, Zhu, Wentao, Huang, Kepu, Hao, Xiaojiang, Zhang, Yu, 2021
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway, YanNi Chen, Xiao Ding, DongMei Li, QingYun Lu, Shuai Liu, YingYao Li, YingTong Di, Xin Fang, XiaoJiang Hao, 2021
Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling, Wang, Yajie, Tan, Jiabin, Hu, Peng, Pei, Qiang, Wen, Yan, Ma, Wenqing, Shi, Keqian, Li, Zengzheng, Li, Huiyuan, Cheng, Fengyu, Gu, Xuezhong, Yao, Xiangmei, Man, Yan, Zhao, Renbin, Feng, Shuai, Ding, Xiao, Yang, Tonghua, 2021
Voacafrines A-N, aspidosperma-type monoterpenoid indole alkaloids from Voacanga africana with AChE inhibitory activity, Zhao, Qian, Zhu, WenTao, Ding, Xiao, Huo, ZongQing, Donkor, Paul O, Adelakun, Tiwalade A, Hao, XiaoJiang, Zhang, Yu, 2021
Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification, Zhang, Yu, Ding, Xiao, Yuan, YuXi, Guo, LingLi, Hao, XiaoJiang, 2020
Acotarines A-G, new diterpenoid alkaloids from Aconitum taronense induce lysosomal biogenesis, Si, Yu, Ding, Xiao, Adelakuna, Tiwalade A, Zhang, Yu, Hao, XiaoJiang, 2020
Inhibitory activities of flavonoids from Eupatorium adenophorum against acetylcholinesterase, Li, Mengyue, Gao, Xi, Lan, Mingxian, Liao, Xianbin, Su, Fawu, Fan, Liming, Zhao, Yuhan, Hao, Xiaojiang, Wu, Guoxing, Ding, Xiao, 2020
Tabernaesines A-I, Cytotoxic Aspidosperma-Aspidosperma-Type Bisindole Alkaloids from Tabernaemontana pachysiphon, Yi, WenFang, Ding, Xiao, Chen, YuanZhi, Adelakun, Tiwalade A, Zhang, Yu, Hao, XiaoJiang, 2020
A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud, Adelakun, Tiwalade A, Ding, Xiao, Ombati, Rose M, Zhao, NingDong, ObodozieOfoegbu, Obiageri, Di, YingTong, Zhang, Yu, Hao, XiaoJiang, 2020
Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis, Chen, YanNi, Ding, Xiao, Lu, QingYun, Li, DongMei, Li, BoTing, Liu, Shuai, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2020
12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata, Gui, PengYan, Yan, XiaoHui, Yuan, WenJuan, Ma, YuanLiang, Ding, Xiao, Liu, Shuai, Di, YingTong, Zhu, WeiMing, Hao, XiaoJiang, 2019
Two New C21 Steroidal Glycosides from the Roots of Cynanchum paniculatum, HaiLi Yu, Qin Long, WenFang Yi, BaoJia Yang, Yu Song, Xiao Ding, ShunLin Li, XiaoJiang Hao, 2019
Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis, Zhang, Yu, Ding, Xiao, Shao, Shun, Guo, LingLi, Zhao, Qing, Hao, XiaoJiang, He, HongPing, 2019
Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense, Duan, XiaoXiang, Qin, Dan, Song, HongChuan, Gao, TianCong, Zuo, ShiHao, Yan, Xiao, Wang, JunQi, Ding, Xiao, Di, YingTong, Dong, JinYan, 2019
Abietane Diterpernoids from the Roots of Euphorbia ebracteolata, YuanLiang Ma, XiaoHan Tang, WenJuan Yuan, Xiao Ding, YingTong Di, XiaoJiang Hao, 2018
Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus, Yi, Wenfang, Chen, Duozhi, Ding, Xiao, Li, Xiaonian, Li, Shunlin, Di, Yingtong, Zhang, Yu, Hao, Xiaojiang, 2018
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death, Li, Yang, Zhang, Yu, Gan, Qiwen, Xu, Meng, Ding, Xiao, Tang, Guihua, Liang, Jingjing, Liu, Kai, Liu, Xuezhao, Wang, Xin, Guo, Lingli, Gao, Zhiyang, Hao, Xiaojiang, Yang, Chonglin, 2018

Chemical Biology: Chemical Biology Molecular Interactions Synthesis Analysis Compounds Mechanisms Pathways Applications Natural Medicinal Chemistry: Natural Medicinal Chemistry Extraction Pharmacology Bioactivity Therapeutic

Zheng Fang - Wuhan University

Chenggang Huang - University of Chinese Academy of Sciences

Minghua Qiu - University of Chinese Academy of Sciences

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