Guanghai Feng
fenggh@ioz.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Medical School
  • 2010-09--2014-06 PhD: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
  • 2007-09--2010-06 Master's Degree: Academy of Military Medical Sciences
  • 2003-09--2007-06 Bachelor's Degree: Shandong University (Weihai)
  • 2024-01~Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
  • 2018-01~2024-01 - Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
  • 2014-07~2018-01 - Institute of Zoology, Chinese Academy of Sciences - Postdoctoral Researcher
  • Outstanding Scientific Achievement Award of the Chinese Academy of Sciences (2020): Collective Award
  • National Maternal and Child Health Science and Technology Award (2019): First Prize in Natural Science
Regenerative Medicine
  • mRNA isoform switches during mouse zygotic genome activation, Guanghai Feng, 2024
  • Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution, Guanghai Feng, 2023
  • Live-cell imaging reveals redox metabolic reprogramming during zygotic genome activation, Guanghai Feng, 2023
  • High-efficiency targeted transgene integration via primed micro-homologues, Guanghai Feng, 2023
  • Influence of feeder cells on transcriptomic analysis of pluripotent stem cells, Guanghai Feng, 2022
  • Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro, Guanghai Feng, 2021
  • TRANSCRIPTOME AND DNA METHYLATION PROFILES OF MOUSE FETUS AND PLACENTA GENERATED BY ROUND SPERMATID INJECTION, Guanghai Feng, 2021
  • Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation, Guanghai Feng, 2020
  • Impaired lipid metabolism by age-dependent DNA methylation alterations accelerates aging, Guanghai Feng, 2020
  • Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer, Guanghai Feng, 2020
  • Transcriptional repression of p21 by EIF1AX promotes the proliferation of breast cancer cells, Guanghai Feng, 2020
  • Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs, Guanghai Feng, 2020
  • Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis, Guanghai Feng, 2020
  • Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon, Guanghai Feng, 2020
  • Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing, Guanghai Feng, 2020
  • Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions, Guanghai Feng, 2019
  • Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I, Guanghai Feng, 2019
  • Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds, Guanghai Feng, 2019
  • Derivation of Mouse Haploid Trophoblast Stem Cells, Guanghai Feng, 2019
  • Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos, Guanghai Feng, 2018
  • MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation, Guanghai Feng, 2018
  • SIRT6 deficiency results in developmental retardation cynomolgus monkeys, Guanghai Feng, 2018
  • RBM14 is indispensable for pluripotency maintenance and mesoderm development of mouse embryonic stem cells, Guanghai Feng, 2018
  • MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer, Guanghai Feng, 2018
  • Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions, Guanghai Feng, 2018
  • Repurposing CRISPR-Cas12b for mammalian genome engineering, Guanghai Feng, 2018
  • Mitochondrially produced ATP affects stem cell pluripotency via ActI6a-mediated histone acetylation, Guanghai Feng, 2018
  • Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis, Guanghai Feng, 2018
  • Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-Wide Genetic Screening, Guanghai Feng, 2017
  • Mettl3-Mediated m6A Regulates Spermatogonial Differentiation and Meiosis Initiation, Guanghai Feng, 2017
  • Rat Embryonic Stem Cells Produce Fertile Offspring Through Tetraploid Complementation, Guanghai Feng, 2017
  • Birth of Fertile Bimaternal Offspring Following Intracytoplasmic Injection of Parthenogenetic Haploid Embryonic Stem Cells, Guanghai Feng, 2016
  • Ubiquitously Expressed Genes Participate in Cell-Specific Functions via Alternative Promoter Usage, Guanghai Feng, 2016
Stem Cells Tissue Engineering Cell Therapy Regeneration Biomedical Research Genetic Engineering Molecular Biology Developmental Biology Clinical Applications Biotechnology

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