De'An Guo
Medical School
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Contact
Quality Standards Traditional Chinese Medicine Analysis Herbal Medicine Pharmacopoeia Natural Products Metabolomics Chromatography Mass Spectrometry Phytochemistry
Areas of Focus
  • Modern Quality Standards for Traditional Chinese Medicine
  • Traditional Chinese Medicine Analysis
Work Experience
  • 1990-07 to 2004-02 - Peking University Health Science Center - Lecturer, Associate Professor, Professor
  • 2015-01-01 to Present - International Society for Chinese Medicine Standardization - President
  • 2014-12-12 to Present - European Pharmacopoeia Commission - Member
  • 2011-03-01 to Present - National Pharmacopoeia Commission - Executive Member, Chair of Natural Medicine Committee
  • 2010-01-01 to Present - United States Pharmacopoeia Commission - Member
Academic Background & Achievements
  • 1987-09 to 1990-07 PhD: Beijing Medical University
Publications
  • Species discrimination of multiple botanical origins of Fritillaria species based on infrared spectroscopy, thin layer chromatography-image analysis and untargeted metabolomics, 11th Author, 2024
  • MATLAB language assisted data acquisition and processing in liquid chromatography Orbitrap mass spectrometry: Application to the identification and differentiation of Radix Bupleuri from its adulterants, 11th Author, 2024
  • An improved strategy for identification and annotation of easily in-sourced dissociation diterpene lactones from plant natural products: Taking Andrographis paniculata (Burm. f.) as an example, 14th Author, 2023
  • Analysis of the lipids of Descurainiae Semen and Lepidii Semen based on three chromatography tandem mass spectrometry techniques, 5th Author, 2023
  • Characterization of the natural peptidome of four leeches by integrated proteogenomics and pseudotargeted peptidomics, 11th Author, 2023
  • Undescribed steroidal alkaloids from the bulbs of Fritillaria sinica, 11th Author, 2023
  • Optimization of Extraction, Hydrolysis and Derivatization of Ginseng Polysaccharide and Comparative Analysis of Monosaccharides of Its Related Species, 6th Author, 2023
  • Characterization of natural peptides in Pheretima by integrating proteogenomics and label-free peptidomics, 11th Author, 2023
  • A pseudotargeted peptidomics strategy for screening natural signature peptides in animal-derived drugs: Taking Pheretima as a case, 11th Author, 2023
  • 中药标准化“三部曲”, 2nd Author, 2022
  • Action proposal of 'telling good stories of traditional Chinese medicine science', 10th Author, 2022
  • Dissecting the Regulation of Arachidonic Acid Metabolites by Uncaria rhynchophylla (Miq). Miq. in Spontaneously Hypertensive Rats and the Predictive Target sEH in the Anti-Hypertensive Effect Based on Metabolomics and Molecular Docking, 0th Author, 2022
  • Research Progress in Anti-tumor Effect of Chinese Herbal Medicines, 6th Author, 2021
  • The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe, 11th Author, 2021
  • Nontargeted metabolomic analysis and multiple criteria decision-making method induced robust quality markers screening for the authentication of herbal medicines from different origins by taking Ophiopogon japonicus L. f. Ker-Gawl. as a case study, 11th Author, 2021
  • Characteristic Malonyl Ginsenosides from the Leaves of Panax notoginseng as Potential Quality Markers for Adulteration Detection, 11th Author, 2021
  • Recent advances in chemical analysis of licorice (Gan-Cao), 11th Author, 2021
  • A strategy for practical authentication of medicinal plants in traditional Chinese medicine prescription, paeony root in ShaoYao-GanCao decoction as a case study, 11th Author, 2021
  • Force iteration molecular designing strategy for the systematic characterization and discovery of new protostane triterpenoids from Alisma Rhizoma by UHPLC/LTQ-Orbitrap-MS, 11th Author, 2021
  • An integrated strategy for holistic quality identification of Chinese patent medicine: Liuwei Dihuang Pills as a case study, 9th Author, 2021
  • Two New Aristolochic Acid Analogues from the Roots of Aristolochia contorta with Significant Cytotoxic Activity, 11th Author, 2021
  • Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos, 4th Author, 2021
  • Simultaneous Determination of Tetrandrine and Fangchindine in Stephania tetrandra from Different Habitats by HPLC, 6th Author, 2021
  • Comprehensive evaluation of NAODESHENG by combining UPLC quantitative fingerprint and antioxidant activity, 11th Author, 2021
  • A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats, 11th Author, 2021
  • Systematic characterization of chemical constituents in Mahuang decoction by UHPLC tandem linear ion trap-Orbitrap mass spectrometry coupled with feature-based molecular networking, 11th Author, 2021
  • Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction, 11th Author, 2021
  • Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases, 10th Author, 2021
  • Exploration of tissue distribution of ginsenoside Rg1 by LC-MS/MS and nanospray desorption electrospray ionization mass spectrometry, 11th Author, 2021
  • A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study, 10th Author, 2021
  • Rapid Determination of 3 Components With Different Polarities in Medicinal Mushrooms by Multistep Matrix Solid-Phase Dispersion and High-Performance Liquid Chromatography Analysis, 11th Author, 2021
  • Simple and robust differentiation of Ganoderma species by high performance thin-layer chromatography coupled with single quadrupole mass spectrometry QDa, 11th Author, 2021
  • Isolation of Protostane Triterpenoids, Nor-triterpenoids and Sesquiterpenes from Rhizoma Alismatis and their Anti-inflammatory Activities Research, 4th Author, 2021
  • On-Line Electrokinetic Supercharging and Sweeping for the Preconcentration and Determination of Nucleosides and Related Compounds by Capillary Electrophoresis, 4th Author, 2020
  • Naphthalene diimide based near-infrared luminogens with aggregation-induced emission characteristics for biological imaging and high mobility ambipolar transistors, Not mentioned, 2020
  • An unexpected reaction of cinobufagin analogues in the presence of PPh3/I-2, 7th Author, 2020
  • Three new bisflavonols from the seeds of Hovenia dulcis Thunb. and their anti-RSV activities, 11th Author, 2020
  • Quality evaluation of Salvianolate for Injection by quantitative analysis of multi-components with single-marker, 9th Author, 2020
  • Highly selective monitoring of in-source fragmentation sapogenin product ions in positive mode enabling group-target ginsenosides profiling and simultaneous identification of seven Panax herbal medicines, 11th Author, 2020
  • Quality assessment of herbal medicines based on chemical fingerprints combined with chemometrics approach: A review, 11th Author, 2020
  • Two new neolignans and one new benzyl benzoate glycoside from Potentilla discolor, 7th Author, 2020
  • Exploring the protective effects of Danqi Tongmai tablet on acute myocardial ischemia rats by comprehensive metabolomics profiling, 11th Author, 2020
  • A metabolomics strategy for authentication of plant medicines with multiple botanical origins, a case study of Uncariae Rammulus Cum Uncis, 11th Author, 2020
  • A novel neutral loss/product ion scan-incorporated integral approach for the untargeted characterization and comparison of the carboxyl-free ginsenosides from Panax ginseng, Panax quinquefolius, and Panax notoginseng, 11th Author, 2020
  • Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network-molecular docking-LC-MS E analysis, 11th Author, 2020
  • Metabolomics Combined with Multivariate Statistical Analysis for Screening of Chemical Markers between Gentiana scabra and Gentiana rigescens, 11th Author, 2020
Awards
  • Zhang Ande International Contribution Award (2016): Other
  • Wu Jieping Medical Innovation Award (2013): Other
  • Research on Systematic Analysis Methods of Active Ingredients in Complex Systems of Traditional Chinese Medicine and Their Application in Quality Standards (2012): National Second Prize
  • Norman R. Farnsworth Excellence in Research Award (2012): Other
  • First Outstanding Contribution Award of the International Conference on Traditional Chinese Medicine (2012): Other
Post a Project

Contact us

Let's talk!
* Required
* Required
* Required
* Invalid email address
By submitting this form, you agree that IoT ONE may contact you with insights and marketing messaging.
No thanks, I don't want to receive any marketing emails from IoT ONE.
Submit

Thank you for your message!
We will contact you soon.