Areas of Focus
- Non-coding RNA in embryonic development
- Directed differentiation of pluripotent stem cells into germ cells
- Molecular mechanisms of somatic cell reprogramming
Work Experience
- 2018-Present - Tongji University, School of Life Sciences and Technology - Professor
- 2012-2018 - Dalian Medical University, Institute of Cancer Stem Cell Research - Professor
- 2007-2012 - Beijing Union Medical College, Beijing Institute of Life Sciences - PhD in Biochemistry and Molecular Biology
Academic Background & Achievements
- 2007-2012 PhD in Biochemistry and Molecular Biology, Beijing Union Medical College, Beijing Institute of Life Sciences
- First to demonstrate complete pluripotency of iPS cells in 2009, widely recognized internationally
- Recipient of multiple national and provincial research grants
- Selected for the National Natural Science Foundation of China Excellent Young Scientist Project
Publications
- LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Kang L#, 2023
- Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Kang L#, 2021
- MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway, Kang L#, 2020
- Historical review of reprogramming and pluripotent stem cell research in China, Kang L, 2018
- Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation, Kang L#, 2017
- LncRNA AC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression, Kang L#, 2017
- Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs, Kang L#, 2017
- NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer, Kang L#, 2017
- The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status, Kang L#, 2015
- The tumor-promoting role of TRIP4 in melanoma progression and its involvement in response to BRAF-targeted therapy, Kang L#, 2017
- Generation of Viable Mice from Induced Pluripotent Stem Cells (iPSCs) Through Tetraploid Complementation, Kang L, 2015
- Cell Type-Specific Expression Profile and Signaling Requirements in Early Hematopoietic Reprogramming, Kang L#, 2015
- Pluripotency of induced pluripotent stem cells, Kang L, 2012
- Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation, Kang L, 2011
- Induced pluripotent stem cells (iPSCs)--a new era of reprogramming, Kang L, 2010
- Mice cloned from induced pluripotent stem cells (iPSCs), Kang L, 2010
- iPS cells can support full term development of tetraploid blastocyst-complemented embryos, Kang L, 2009
