Professor | Kang Lan | Asia Growth Partners

Name	Kang Lan
Contact Information	kanglan@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Kang Lan

Contact Information

kanglan@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2007-2012 PhD in Biochemistry and Molecular Biology, Beijing Union Medical College, Beijing Institute of Life Sciences First to demonstrate complete pluripotency of iPS cells in 2009, widely recognized internationally Recipient of multiple national and provincial research grants Selected for the National Natural Science Foundation of China Excellent Young Scientist Project
Work Experience	2018-Present - Tongji University, School of Life Sciences and Technology - Professor 2012-2018 - Dalian Medical University, Institute of Cancer Stem Cell Research - Professor 2007-2012 - Beijing Union Medical College, Beijing Institute of Life Sciences - PhD in Biochemistry and Molecular Biology

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2007-2012 PhD in Biochemistry and Molecular Biology, Beijing Union Medical College, Beijing Institute of Life Sciences
First to demonstrate complete pluripotency of iPS cells in 2009, widely recognized internationally
Recipient of multiple national and provincial research grants
Selected for the National Natural Science Foundation of China Excellent Young Scientist Project

Work Experience

2018-Present - Tongji University, School of Life Sciences and Technology - Professor
2012-2018 - Dalian Medical University, Institute of Cancer Stem Cell Research - Professor
2007-2012 - Beijing Union Medical College, Beijing Institute of Life Sciences - PhD in Biochemistry and Molecular Biology

Areas of Focus	Non-coding RNA in embryonic development Directed differentiation of pluripotent stem cells into germ cells Molecular mechanisms of somatic cell reprogramming
Publications	LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Kang L#, 2023 Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Kang L#, 2021 MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway, Kang L#, 2020 Historical review of reprogramming and pluripotent stem cell research in China, Kang L, 2018 Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation, Kang L#, 2017 LncRNA AC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression, Kang L#, 2017 Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs, Kang L#, 2017 NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer, Kang L#, 2017 The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status, Kang L#, 2015 The tumor-promoting role of TRIP4 in melanoma progression and its involvement in response to BRAF-targeted therapy, Kang L#, 2017 Generation of Viable Mice from Induced Pluripotent Stem Cells (iPSCs) Through Tetraploid Complementation, Kang L, 2015 Cell Type-Specific Expression Profile and Signaling Requirements in Early Hematopoietic Reprogramming, Kang L#, 2015 Pluripotency of induced pluripotent stem cells, Kang L, 2012 Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation, Kang L, 2011 Induced pluripotent stem cells (iPSCs)--a new era of reprogramming, Kang L, 2010 Mice cloned from induced pluripotent stem cells (iPSCs), Kang L, 2010 iPS cells can support full term development of tetraploid blastocyst-complemented embryos, Kang L, 2009

Areas of Focus

Non-coding RNA in embryonic development
Directed differentiation of pluripotent stem cells into germ cells
Molecular mechanisms of somatic cell reprogramming

Publications

LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Kang L#, 2023
Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Kang L#, 2021
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway, Kang L#, 2020
Historical review of reprogramming and pluripotent stem cell research in China, Kang L, 2018
Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation, Kang L#, 2017
LncRNA AC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression, Kang L#, 2017
Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs, Kang L#, 2017
NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer, Kang L#, 2017
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status, Kang L#, 2015
The tumor-promoting role of TRIP4 in melanoma progression and its involvement in response to BRAF-targeted therapy, Kang L#, 2017
Generation of Viable Mice from Induced Pluripotent Stem Cells (iPSCs) Through Tetraploid Complementation, Kang L, 2015
Cell Type-Specific Expression Profile and Signaling Requirements in Early Hematopoietic Reprogramming, Kang L#, 2015
Pluripotency of induced pluripotent stem cells, Kang L, 2012
Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation, Kang L, 2011
Induced pluripotent stem cells (iPSCs)--a new era of reprogramming, Kang L, 2010
Mice cloned from induced pluripotent stem cells (iPSCs), Kang L, 2010
iPS cells can support full term development of tetraploid blastocyst-complemented embryos, Kang L, 2009

Non-Coding Rna Embryonic Development Regulation Mechanisms Pluripotent Stem Cells Germ Cells Differentiation Somatic Cell Reprogramming Molecular Mechanisms Cellular Biology

Zengyi Chang - Peking University

Lan Kang - Tongji University

Yongchun Yu - Fudan University

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