Jingtao Guo
Medical School
University of Chinese Academy of Sciences
Beijing
Language: English, Chinese
Contact
Developmental Biology: Embryogenesis Cell Differentiation Morphogenesis Organogenesis Stem Cells Gene Expression Signaling Pathways Tissue Engineering Model Organisms Developmental Disorders Reproductive Biology: Gametogenesis Fertilization Reproductive Health Infertility Hormonal Regulation Reproductive Organs Assisted Reproduction Reproductive Aging Reproductive Genetics Reproductive Endocrinology Genomics: Dna Sequencing Gene Mapping Genetic Variation Genome Editing Bioinformatics Epigenomics Transcriptomics Functional Genomics Comparative Genomics Population Genomics
Areas of Focus
  • Developmental Biology
  • Reproductive Biology
  • Genomics
Work Experience
  • 2021-12~Present - Chinese Academy of Sciences Institute of Zoology - Researcher
  • 2020-07~2021-11 - University of Utah School of Medicine - Assistant Professor
  • 2018-08~2020-07 - University of Utah School of Medicine - Postdoctoral Fellow
Academic Background & Achievements
  • 2013-08--2018-06 PhD: University of Utah School of Medicine
  • 2009-09--2013-07 Bachelor of Science: Peking University School of Life Sciences
Publications
  • Single-cell analysis of human testis aging and correlation with elevated body mass index, Xichen Nie, Sarah K Munyoki, Meena Sukhwani, Nina Schmid, Annika Missel, Benjamin R Emery, DonorConnect, JanBernd Stukenborg, Artur Mayerhofer, Kyle E Orwig, Kenneth I Aston, James M Hotaling, Bradley R Cairns, Jingtao Guo, 2022
  • p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models, Grow, Edward J, Weaver, Bradley D, Smith, Christina M, Guo, Jingtao, Stein, Paula, Shadle, Sean C, Hendrickson, Peter G, Johnson, Nicholas E, Butterfield, Russell J, Menafra, Roberta, Kloet, Susan L, van der Maarel, Silvere M, Williams, Carmen J, Cairns, Bradley R, 2021
  • Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome, Mahyari, Eisa, Guo, Jingtao, Lima, Ana C, Lewinsohn, Daniel P, Stendahl, Alexandra M, VighConrad, Katinka A, Nie, Xichen, Nagirnaja, Liina, Rockweiler, Nicole B, Carrell, Douglas T, Hotaling, James M, Aston, Kenneth, I, Conrad, Donald F, 2021
  • Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment, Guo, Jingtao, Sosa, Enrique, Chitiashvili, Tsotne, Nie, Xichen, Rojas, Ernesto Javier, Oliver, Elizabeth, Plath, Kathrin, Hotaling, James M, Stukenborg, JanBernd, Clark, Amander T, Cairns, Bradley R, DonorConnect, 2021
  • The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty, Guo, Jingtao, Nie, Xichen, Giebler, Maria, Mlcochova, Hana, Wang, Yueqi, Grow, Edward J, DonorConnect, Kim, Robin, Tharmalingam, Melissa, Matilionyte, Gabriele, Lindskog, Cecilia, Carrell, Douglas T, Mitchell, Rod T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R, 2020
  • NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure, Patrick J Murphy, Jingtao Guo, Timothy G Jenkins, Emma R James, John R Hoidal, Thomas Huecksteadt, Dallin S Broberg, James M Hotaling, David F Alonso, Douglas T Carrell, Bradley R Cairns, Kenneth I Aston, 2020
  • Isolation and Enrichment of Spermatogonial Stem Cells from Human Testis Tissues, Guo Jingtao, 2019
  • The adult human testis transcriptional cell atlas, Guo, Jingtao, Grow, Edward J, Mlcochova, Hana, Maher, Geoffrey J, Lindskog, Cecilia, Nie, Xichen, Guo, Yixuan, Takei, Yodai, Yun, Jina, Cai, Long, Kim, Robin, Carrell, Douglas T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R, 2018
  • Chromatin and Single-Cell RNA- Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development, Guo, Jingtao, Grow, Edward J, Yi, Chongil, Mlcochova, Hana, Maher, Geoffrey J, Lindskog, Cecilia, Murphy, Patrick J, Wike, Candice L, Carrell, Douglas T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R, 2017
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