Han Haihao
hanhaihao@simm.ac.cn
Chinese, English
Shandong
University of Chinese Academy of Sciences
Medical School
Development of probes and drug molecules for disease-targeted diagnosis and treatment
  • NIR-II fluorescence lateral flow immunosensor based on efficient energy transfer probe for point-of-care testing of tumor biomarkers, Corresponding Author, 2024
  • The development of logic gate-based fluorescent probes that respond to intracellular hydrogen peroxide and pH in tandem, First Author, 2024
  • Selective FRET nano probe based on carbon dots and naphthalimide-isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury, Corresponding Author, 2024
  • Protein-encapsulated long-wavelength fluorescent probe hybrid for imaging lipid droplets in living cells and mice with non-alcoholic fatty liver, Corresponding Author, 2024
  • Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore, Second Author, 2023
  • Fluorescence-based chemical tools for monitoring ultrasound-induced hydroxyl radical production in aqueous solution and in cells, Corresponding Author, 2023
  • A Highly Sensitive and Selective Near-Infrared Fluorescent Probe for Imaging Peroxynitrite in Living Cells and Drug-Induced Liver Injury Mice, Corresponding Author, 2023
  • The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy, First Author, 2023
  • Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy, Third Author, 2022
  • Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial, Corresponding Author, 2022
  • Fluorescent probes for the detection of disease-associated biomarkers, Second Author, 2022
  • Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5 '-triphosphate in Cellular Applications, Corresponding Author, 2022
  • A long-wavelength fluorescent probe with a large Stokes shift for lysosome-targeted imaging of Cys and GSH, Second Author, 2021
  • Fluorescent probes for the imaging of lipid droplets in live cells, Third Author, 2021
  • In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics, Third Author, 2021
  • A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters, Third Author, 2021
  • Deferasirox (ExJade): An FDA-Approved AIEgen Platform with Unique Photophysical Properties, Sixth Author, 2021
  • Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells, Second Author, 2021
  • Small-molecule fluorescence-based probes for interrogating major organ diseases, First Author, 2021
  • Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes, First Author, 2020
  • Pinkment: a synthetic platform for the development of fluorescent probes for diagnostic and theranostic applications, Second Author, 2020
  • Supramolecular Assembly of TPE-Based Glycoclusters with Dicyanomethylene-4H-pyran (DM) Fluorescent Probes Improve Their Properties for Peroxynitrite Sensing and Cell Imaging, Fourth Author, 2020
  • Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers, Second Author, 2020
  • Protein Encapsulation: A Nanocarrier Approach to the Fluorescence Imaging of an Enzyme-Based Biomarker, Second Author, 2020
  • Self-Assembled Thin-Layer Glycomaterials With a Proper Shell Thickness for Targeted and Activatable Cell Imaging, Third Author, 2019
  • ESIPT-based fluorescence probe for the ratiometric detection of superoxide, Third Author, 2019
  • Targeted photoswitchable imaging of intracellular glutathione by a photochromic glycosheet sensor, Second Author, 2019
  • Peroxynitrite Activated Drug Conjugate Systems Based on a Coumarin Scaffold Toward the Application of Theranostics, Second Author, 2019
  • Glypican-3-targeted precision diagnosis of hepatocellular carcinoma on clinical sections with a supramolecular 2D imaging probe, First Author, 2018
  • The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH, Second Author, 2018
  • Photocontrolled Fluorescence \"Double-Check\" Bioimaging Enabled by a Glycoprobe-Protein Hybrid, Second Author, 2018
  • Remote light-controlled intracellular target recognition by photochromic fluorescent glycoprobes, Third Author, 2017
  • Sialylglycan-Assembled Supra-Dots for Ratiometric Probing and Blocking of Human-Infecting Influenza Viruses, Second Author, 2017
  • Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite, Second Author, 2017
  • Supramolecular core-glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy, First Author, 2017
Probes Drug Molecules Disease-Targeted Diagnosis Treatment Fluorescent Probes Biomarkers Imaging Theranostics Photodynamic Therapy

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