Professor | Shiqiang Huang | Asia Growth Partners

Name	Shiqiang Huang
Contact Information	huangsq@ioz.ac.cn
Language ability	English, Chinese
Province	Beijing

Name

Shiqiang Huang

Contact Information

huangsq@ioz.ac.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2009-09--2013-11 Ph.D.: Harvard University 2005-08--2008-05 B.A.: Princeton University
Awards	HHMI International Research Scholar (2018): Special Award

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2009-09--2013-11 Ph.D.: Harvard University
2005-08--2008-05 B.A.: Princeton University

Awards

HHMI International Research Scholar (2018): Special Award

Areas of Focus	Stem Cells Metabolomics Regenerative Medicine
Publications	Spatial metabolomics reveals skeletal myofiber subtypes, Shiqiang Huang, 2023 Adult progenitor rejuvenation with embryonic factor, Shiqiang Huang, 2023 Muscle Injuries Induce a Prostacyclin-PPARγ/PGC1a-FAO Spike That Boosts Regeneration, Shiqiang Huang, 2023 XAI-enabled neural network analysis of metabolite spatial distributions, Shiqiang Huang, 2023 Controllable assembly of skeletal muscle-like bundles through 3D bioprinting, Fan, Tingting, Wang, Shuo, Jiang, Zongmin, Ji, Shen, Cao, Wenhua, Liu, Wenli, Ji, Yun, Li, Yujing, ShyhChang, Ng, Gu, Qi, 2022 Machine learning‐based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small molecule ribosome agonists, Zongmin Jiang, Liping Zhang, Ziyue Yao, Wenhua Cao, Shilin Ma, Yu Chen, Lu Guang, Zipeng Zheng, Chunwei Li, Kang Yu, Ng ShyhChang, 2022 The Metabaging Cycle, Ma, Shilin, ShyhChang, Ng, 2022 Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor, Zunpeng Liu, Wei Li, Lingling Geng, Liang Sun, Qiaoran Wang, Yang Yu, Pengze Yan, Chuqian Liang, Jie Ren, Moshi Song, Qian Zhao, Jinghui Lei, Yusheng Cai, Jiaming Li, Kaowen Yan, Zeming Wu, Qun Chu, Jingyi Li, Si Wang, Chunyi Li, JingDong J Han, Reyna HernandezBenitez, Ng ShyhChang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, GuangHui Liu, 2022 Construction of a cross-species cell landscape at single-cell level, Wang, Renying, Zhang, Peijing, Wang, Jingjing, Ma, Lifeng, Weigao, E, Suo, Shengbao, Jiang, Mengmeng, Li, Jiaqi, Chen, Haide, Sun, Huiyu, Fei, Lijiang, Zhou, Ziming, Zhou, Yincong, Chen, Yao, Zhang, Weiqi, Wang, Xinru, Mei, Yuqing, Sun, Zhongyi, Yu, Chengxuan, Shao, Jikai, Fu, Yuting, Xiao, Yanyu, Ye, Fang, Fang, Xing, Wu, Hanyu, Guo, Qile, Fang, Xiunan, Li, Xia, Gao, Xianzhi, Wang, Dan, Xu, PengFei, Zeng, Rui, Xu, Gang, Zhu, Lijun, Wang, Lie, Qu, Jing, Zhang, Dan, Ouyang, Hongwei, Huang, He, Chen, Ming, Ng, ShyhChang, Liu, GuangHui, Yuan, GuoCheng, Guo, Guoji, Han, Xiaoping, 2022 An RNA methylation code to regulate protein translation and cell fate, Song, Dan, ShyhChang, Ng, 2022 Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review, Chunwei Li, Kang Yu, Ng ShyhChang, Zongmin Jiang, Taoyan Liu, Shilin Ma, Lanfang Luo, Lu Guang, Kun Liang, Wenwu Ma, Hefan Miao, Wenhua Cao, Ruirui Liu, Lingjuan Jiang, Songlin Yu, Chao Li, Huijun Liu, Longyu Xu, Rongji Liu, Xinyuan Zhang, Gaoshan Liu, 2022 Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs, Liang, Lingmin, Tian, Yao, Feng, Lin, Wang, Chaoqun, Feng, Guihai, Stacey, Glyn Nigel, ShyhChang, Ng, Wu, Jun, Hu, Baoyang, Li, Wei, Hao, Jie, Wang, Liu, Wang, Yukai, 2022 Developing standards to support cell technology applications, Cao, Jiani, Stacey, Glyn, ShyhChang, Ng, Zhao, Tongbiao, 2022 Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia, Chew, Elaine G Y, Lim, Tze Chiun, Leong, Meng Fatt, Liu, Xingliang, Sia, Yee Yen, Leong, See Ting, YanJiang, Benjamin C, Stoecklin, Celine, Borhan, Rosa, HeilmannHeimbach, Stefanie, Nothen, Markus M, Viasnoff, Virgile, ShyhChang, Ng, Wan, Andrew C A, Philpott, Michael P, Hillmer, Axel M, 2022 Sterol metabolism and protein metabolism are differentially correlated with sarcopenia in Asian Chinese men and women, Li, ChunWei, Yu, Kang, ShyhChang, Ng, Li, GuoXun, Yu, SongLin, Liu, HuiJun, Yang, Bo, Li, ZiYao, Zhao, YongJie, Xu, LongYu, Xu, Jing, Jiang, LingJuan, Liu, RongJi, Zhang, XinYuan, Li, ShaoFei, Zhang, XiaoWei, Xie, HaiYan, Li, Kang, Zhan, YiXiang, Cui, Min, Tao, HangBo, Li, Yao, Liu, GaoShan, Ni, KeMin, Li, DongJing, 2021 Stabilizing Formative Pluripotent States with Germ Cell Competency, ShyhChang, Ng, Li, Lei, 2021 Formative pluripotent stem cells show features of epiblast cells poised for gastrulation, Wang, Xiaoxiao, Xiang, Yunlong, Yu, Yang, Wang, Ran, Zhang, Yu, Xu, Qianhua, Sun, Hao, Zhao, ZhenAo, Jiang, Xiangxiang, Wang, Xiaoqing, Lu, Xukun, Qin, Dandan, Quan, Yujun, Zhang, Jiaqi, ShyhChang, Ng, Wang, Hongmei, Jing, Naihe, Xie, Wei, Li, Lei, 2021 Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells, Liu, Tong Ming, Yildirim, Ege Deniz, Li, Pin, Fang, Hai Tong, Denslin, Vinitha, Kumar, Vibhor, Loh, Yuin Han, Lee, Eng Hin, Cool, Simon M, Teh, Bin Tean, Hui, James H, Lim, Bing, ShyhChang, Ng, 2020 Chromatin-modifying drugs and metabolites in cell fate control, Yao, Ziyue, Chen, Yu, Cao, Wenhua, ShyhChang, Ng, 2020 Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, Xu, YaJie, Liu, PeiPei, Ng, ShyhChang, Teng, ZhaoQian, Liu, ChangMei, 2020 Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis, Wu, Jun, Song, Dingyun, Li, Zhongwen, Guo, Baojie, Xiao, Yani, Liu, Wenjing, Liang, Lingmin, Feng, Chunjing, Gao, Tingting, Chen, Yanxia, Li, Ying, Wang, Zai, Wen, Jianyan, Yang, Shengnan, Liu, Peipei, Wang, Lei, Wang, Yukai, Peng, Liang, Stacey, Glyn Nigel, Hu, Zheng, Feng, Guihai, Li, Wei, Huo, Yan, Jin, Ronghua, ShyhChang, Ng, Zhou, Qi, Wang, Liu, Hu, Baoyang, Dai, Huaping, Hao, Jie, 2020 DNA Torsion-based Model of Cell Fate Phase Transitions, ShyhChang Ng, Luo Liaofu, 2020 HNF4 alpha pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer, Xu, Chang, Ooi, Wen Fong, Qamra, Aditi, Tan, Jing, Chua, Benjamin YanJiang, Ho, Shamaine Wei Ting, Das, Kakoli, Isa, Zul Fazreen Adam, Li, Zhimei, Yao, Xiaosai, Yan, Tingdong, Xing, Manjie, Huang, Kie Kyon, Lin, Joyce Suling, Nandi, Tannistha, Tay, Su Ting, Lee, Ming Hui, Tan, Angie Lay Keng, Ong, Xuewen, Ashktorab, Hassan, Smoot, Duane, Li, Shang, Ng, ShyhChang, Teh, Bin Tean, Tan, Patrick, 2020 Oncofetal SALL4-Driven Tumorigenesis Is Highly Dependent on Oxidative Phosphorylation, Revealing Therapeutic Opportunities, Liu, Taoyan, Ng ShyhChang, 2019 Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention, Li, Chunwei, Yu, Kang, ShyhChang, Ng, Li, Guoxun, Jiang, Lingjuan, Yu, Songlin, Xu, Longyu, Liu, Rongji, Guo, Zijian, Xie, Haiyan, Li, Rongrong, Ying, Jie, Li, Kang, Li, Dongjing, 2019 Putting Stem Cells on a Low-Fat Diet Switches Their Pluripotent State, Jiang, Zongmin, Guang, Lu, Li, Lei, Ng ShyhChang, 2019 Assessment of different strategies for scalable production and proliferation of human myoblasts, Chua, MinWen Jason, Yildirim, Ege Deniz, Tan, JunHao Elwin, Chua, YanJiang Benjamin, Low, SuetMei Crystal, Ding, Suet Lee Shirley, Li, Chunwei, Jiang, Zongmin, Teh, Bin Tean, Yu, Kang, ShyhChang, Ng, 2019 Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis, Zhang, Xing, Liu, Zunpeng, Liu, Xiaoqian, Wang, Si, Zhang, Yiyuan, He, Xiaojuan, Sun, Shuhui, Ma, Shuai, Ng ShyhChang, Liu, Feng, Wang, Qiang, Wang, Xiaoqun, Liu, Lin, Zhang, Weiqi, Song, Moshi, Liu, GuangHui, Qu, Jing, 2019 Efficient RNA drug delivery using red blood cell extracellular vesicles, Waqas Muhammad Usman, Tin Chanh Pham, Yuk Yan Kwok, Luyen Tien Vu, Victor Ma, Boya Peng, Yuen San Chan, Likun Wei, Siew Mei Chin, Ajijur Azad, Alex BaiLiang He, Anskar Y H Leung, Mengsu Yang, Ng ShyhChang, William C Cho, Jiahai Shi, Minh T N Le, 2018 Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation, Lee, HoJoon, Jedrychowski, Mark P, Vinayagam, Arunachalam, Wu, Ning, ShyhChang, Ng, Hu, Yanhui, MinWen, Chua, Moore, Jodene K, Asara, John M, Lyssiotis, Costas A, Perrimon, Norbert, Gygi, Steven P, Cantley, Lewis C, Kirschner, Marc W, 2017 Polyurethane acrylates as effective substrates for sustained in vitro culture of human myotubes, Andriani, Yosephine, Chua, Jason MinWen, Chua, Benjamin YanJiang, Phang, In Yee, ShyhChang, Ng, Tan,

Areas of Focus

Stem Cells
Metabolomics
Regenerative Medicine

Publications

Spatial metabolomics reveals skeletal myofiber subtypes, Shiqiang Huang, 2023
Adult progenitor rejuvenation with embryonic factor, Shiqiang Huang, 2023
Muscle Injuries Induce a Prostacyclin-PPARγ/PGC1a-FAO Spike That Boosts Regeneration, Shiqiang Huang, 2023
XAI-enabled neural network analysis of metabolite spatial distributions, Shiqiang Huang, 2023
Controllable assembly of skeletal muscle-like bundles through 3D bioprinting, Fan, Tingting, Wang, Shuo, Jiang, Zongmin, Ji, Shen, Cao, Wenhua, Liu, Wenli, Ji, Yun, Li, Yujing, ShyhChang, Ng, Gu, Qi, 2022
Machine learning‐based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small molecule ribosome agonists, Zongmin Jiang, Liping Zhang, Ziyue Yao, Wenhua Cao, Shilin Ma, Yu Chen, Lu Guang, Zipeng Zheng, Chunwei Li, Kang Yu, Ng ShyhChang, 2022
The Metabaging Cycle, Ma, Shilin, ShyhChang, Ng, 2022
Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor, Zunpeng Liu, Wei Li, Lingling Geng, Liang Sun, Qiaoran Wang, Yang Yu, Pengze Yan, Chuqian Liang, Jie Ren, Moshi Song, Qian Zhao, Jinghui Lei, Yusheng Cai, Jiaming Li, Kaowen Yan, Zeming Wu, Qun Chu, Jingyi Li, Si Wang, Chunyi Li, JingDong J Han, Reyna HernandezBenitez, Ng ShyhChang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, GuangHui Liu, 2022
Construction of a cross-species cell landscape at single-cell level, Wang, Renying, Zhang, Peijing, Wang, Jingjing, Ma, Lifeng, Weigao, E, Suo, Shengbao, Jiang, Mengmeng, Li, Jiaqi, Chen, Haide, Sun, Huiyu, Fei, Lijiang, Zhou, Ziming, Zhou, Yincong, Chen, Yao, Zhang, Weiqi, Wang, Xinru, Mei, Yuqing, Sun, Zhongyi, Yu, Chengxuan, Shao, Jikai, Fu, Yuting, Xiao, Yanyu, Ye, Fang, Fang, Xing, Wu, Hanyu, Guo, Qile, Fang, Xiunan, Li, Xia, Gao, Xianzhi, Wang, Dan, Xu, PengFei, Zeng, Rui, Xu, Gang, Zhu, Lijun, Wang, Lie, Qu, Jing, Zhang, Dan, Ouyang, Hongwei, Huang, He, Chen, Ming, Ng, ShyhChang, Liu, GuangHui, Yuan, GuoCheng, Guo, Guoji, Han, Xiaoping, 2022
An RNA methylation code to regulate protein translation and cell fate, Song, Dan, ShyhChang, Ng, 2022
Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review, Chunwei Li, Kang Yu, Ng ShyhChang, Zongmin Jiang, Taoyan Liu, Shilin Ma, Lanfang Luo, Lu Guang, Kun Liang, Wenwu Ma, Hefan Miao, Wenhua Cao, Ruirui Liu, Lingjuan Jiang, Songlin Yu, Chao Li, Huijun Liu, Longyu Xu, Rongji Liu, Xinyuan Zhang, Gaoshan Liu, 2022
Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs, Liang, Lingmin, Tian, Yao, Feng, Lin, Wang, Chaoqun, Feng, Guihai, Stacey, Glyn Nigel, ShyhChang, Ng, Wu, Jun, Hu, Baoyang, Li, Wei, Hao, Jie, Wang, Liu, Wang, Yukai, 2022
Developing standards to support cell technology applications, Cao, Jiani, Stacey, Glyn, ShyhChang, Ng, Zhao, Tongbiao, 2022
Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia, Chew, Elaine G Y, Lim, Tze Chiun, Leong, Meng Fatt, Liu, Xingliang, Sia, Yee Yen, Leong, See Ting, YanJiang, Benjamin C, Stoecklin, Celine, Borhan, Rosa, HeilmannHeimbach, Stefanie, Nothen, Markus M, Viasnoff, Virgile, ShyhChang, Ng, Wan, Andrew C A, Philpott, Michael P, Hillmer, Axel M, 2022
Sterol metabolism and protein metabolism are differentially correlated with sarcopenia in Asian Chinese men and women, Li, ChunWei, Yu, Kang, ShyhChang, Ng, Li, GuoXun, Yu, SongLin, Liu, HuiJun, Yang, Bo, Li, ZiYao, Zhao, YongJie, Xu, LongYu, Xu, Jing, Jiang, LingJuan, Liu, RongJi, Zhang, XinYuan, Li, ShaoFei, Zhang, XiaoWei, Xie, HaiYan, Li, Kang, Zhan, YiXiang, Cui, Min, Tao, HangBo, Li, Yao, Liu, GaoShan, Ni, KeMin, Li, DongJing, 2021
Stabilizing Formative Pluripotent States with Germ Cell Competency, ShyhChang, Ng, Li, Lei, 2021
Formative pluripotent stem cells show features of epiblast cells poised for gastrulation, Wang, Xiaoxiao, Xiang, Yunlong, Yu, Yang, Wang, Ran, Zhang, Yu, Xu, Qianhua, Sun, Hao, Zhao, ZhenAo, Jiang, Xiangxiang, Wang, Xiaoqing, Lu, Xukun, Qin, Dandan, Quan, Yujun, Zhang, Jiaqi, ShyhChang, Ng, Wang, Hongmei, Jing, Naihe, Xie, Wei, Li, Lei, 2021
Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells, Liu, Tong Ming, Yildirim, Ege Deniz, Li, Pin, Fang, Hai Tong, Denslin, Vinitha, Kumar, Vibhor, Loh, Yuin Han, Lee, Eng Hin, Cool, Simon M, Teh, Bin Tean, Hui, James H, Lim, Bing, ShyhChang, Ng, 2020
Chromatin-modifying drugs and metabolites in cell fate control, Yao, Ziyue, Chen, Yu, Cao, Wenhua, ShyhChang, Ng, 2020
Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, Xu, YaJie, Liu, PeiPei, Ng, ShyhChang, Teng, ZhaoQian, Liu, ChangMei, 2020
Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis, Wu, Jun, Song, Dingyun, Li, Zhongwen, Guo, Baojie, Xiao, Yani, Liu, Wenjing, Liang, Lingmin, Feng, Chunjing, Gao, Tingting, Chen, Yanxia, Li, Ying, Wang, Zai, Wen, Jianyan, Yang, Shengnan, Liu, Peipei, Wang, Lei, Wang, Yukai, Peng, Liang, Stacey, Glyn Nigel, Hu, Zheng, Feng, Guihai, Li, Wei, Huo, Yan, Jin, Ronghua, ShyhChang, Ng, Zhou, Qi, Wang, Liu, Hu, Baoyang, Dai, Huaping, Hao, Jie, 2020
DNA Torsion-based Model of Cell Fate Phase Transitions, ShyhChang Ng, Luo Liaofu, 2020
HNF4 alpha pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer, Xu, Chang, Ooi, Wen Fong, Qamra, Aditi, Tan, Jing, Chua, Benjamin YanJiang, Ho, Shamaine Wei Ting, Das, Kakoli, Isa, Zul Fazreen Adam, Li, Zhimei, Yao, Xiaosai, Yan, Tingdong, Xing, Manjie, Huang, Kie Kyon, Lin, Joyce Suling, Nandi, Tannistha, Tay, Su Ting, Lee, Ming Hui, Tan, Angie Lay Keng, Ong, Xuewen, Ashktorab, Hassan, Smoot, Duane, Li, Shang, Ng, ShyhChang, Teh, Bin Tean, Tan, Patrick, 2020
Oncofetal SALL4-Driven Tumorigenesis Is Highly Dependent on Oxidative Phosphorylation, Revealing Therapeutic Opportunities, Liu, Taoyan, Ng ShyhChang, 2019
Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention, Li, Chunwei, Yu, Kang, ShyhChang, Ng, Li, Guoxun, Jiang, Lingjuan, Yu, Songlin, Xu, Longyu, Liu, Rongji, Guo, Zijian, Xie, Haiyan, Li, Rongrong, Ying, Jie, Li, Kang, Li, Dongjing, 2019
Putting Stem Cells on a Low-Fat Diet Switches Their Pluripotent State, Jiang, Zongmin, Guang, Lu, Li, Lei, Ng ShyhChang, 2019
Assessment of different strategies for scalable production and proliferation of human myoblasts, Chua, MinWen Jason, Yildirim, Ege Deniz, Tan, JunHao Elwin, Chua, YanJiang Benjamin, Low, SuetMei Crystal, Ding, Suet Lee Shirley, Li, Chunwei, Jiang, Zongmin, Teh, Bin Tean, Yu, Kang, ShyhChang, Ng, 2019
Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis, Zhang, Xing, Liu, Zunpeng, Liu, Xiaoqian, Wang, Si, Zhang, Yiyuan, He, Xiaojuan, Sun, Shuhui, Ma, Shuai, Ng ShyhChang, Liu, Feng, Wang, Qiang, Wang, Xiaoqun, Liu, Lin, Zhang, Weiqi, Song, Moshi, Liu, GuangHui, Qu, Jing, 2019
Efficient RNA drug delivery using red blood cell extracellular vesicles, Waqas Muhammad Usman, Tin Chanh Pham, Yuk Yan Kwok, Luyen Tien Vu, Victor Ma, Boya Peng, Yuen San Chan, Likun Wei, Siew Mei Chin, Ajijur Azad, Alex BaiLiang He, Anskar Y H Leung, Mengsu Yang, Ng ShyhChang, William C Cho, Jiahai Shi, Minh T N Le, 2018
Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation, Lee, HoJoon, Jedrychowski, Mark P, Vinayagam, Arunachalam, Wu, Ning, ShyhChang, Ng, Hu, Yanhui, MinWen, Chua, Moore, Jodene K, Asara, John M, Lyssiotis, Costas A, Perrimon, Norbert, Gygi, Steven P, Cantley, Lewis C, Kirschner, Marc W, 2017
Polyurethane acrylates as effective substrates for sustained in vitro culture of human myotubes, Andriani, Yosephine, Chua, Jason MinWen, Chua, Benjamin YanJiang, Phang, In Yee, ShyhChang, Ng, Tan,

Stem Cells Regenerative Medicine Metabolomics Tissue Engineering Cell Therapy Biomarkers Muscle Regeneration Aging Embryology Histology

Xia Li - Southern University of Science and Technology

Yueshan Lei - Wuhan University

Jing Qu - University of Chinese Academy of Sciences

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