Areas of Focus
- Stem Cells
- Neurodegenerative Diseases
- Reprogramming
- Transdifferentiation
- Non-coding RNA
- Induced Pluripotent Stem Cells
- Cell Fate Regulation
Work Experience
- 1991-1992 - University of Navarra, Department of Pathology - Research Assistant
- 1992-1993 - University of Navarra, Department of Microbiology - Research Assistant
- 1995-1998 - Princess Hospital (Madrid), Emergency Department - Rotating Doctor
- 2003-2007 - Imperial College London, Faculty of Medicine, Renal Laboratory - Associate Researcher
- 2008 to present - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, South China Institute for Stem Cell Biology and Regenerative Medicine - Chief Researcher
Academic Background & Achievements
- 1999-09 to 2003-06 PhD: Autonomous University of Madrid
- 1988-09 to 1994-06 Bachelor's: University of Navarra
Publications
- Capture of the newly transcribed RNA interactome using click chemistry, Miguel Angel Esteban, 2021
- Global Profiling of the Lysine Crotonylome in Different Pluripotent States, Miguel Angel Esteban, 2021
- beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus, Miguel Angel Esteban, 2020
- JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency, Miguel Angel Esteban, 2020
- Generation of induced pluripotent stem cell line (ZZUi011-A) from urine sample of a normal human, Miguel Angel Esteban, 2018
- Ncor/smrt co-repressors cooperate with c-myc to create an epigenetic barrier to somatic cell reprogramming, Miguel Angel Esteban, 2018
- Capturing the interactome of newly transcribed RNA, Miguel Angel Esteban, 2018
- Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1, Miguel Angel Esteban, 2017
- Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells, Miguel Angel Esteban, 2017
- Transcriptional Control of Somatic Cell Reprogramming, Miguel Angel Esteban, 2016
- LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration, Miguel Angel Esteban, 2015
- Characterization of a novel cell penetrating peptide derived from human Oct4, Miguel Angel Esteban, 2014
- Solving the puzzle of Parkinson's disease using induced pluripotent stem cells, Miguel Angel Esteban, 2014
- Generation of knockout rabbits using transcription activator-like effector nucleases, Miguel Angel Esteban, 2014
- Transcriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming, Miguel Angel Esteban, 2014
- Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C, Miguel Angel Esteban, 2011
- MicroRNA Cluster 302-367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition, Miguel Angel Esteban, 2011
- Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases, Miguel Angel Esteban, 2010
- Porcine induced pluripotent stem cell may bridge the gap between mouse and human ips, Miguel Angel Esteban, 2010
- A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts, Miguel Angel Esteban, 2010
- Induced pluripotent stem cell can be used to model the genomic imprinting disorder prader-willi syndrome, Miguel Angel Esteban, 2010
- Vitamin C enhances the generation of mouse and human induced pluripotent stem cell, Miguel Angel Esteban, 2010
- VHL Inactivation Induces HEF1 and Aurora Kinase A, Miguel Angel Esteban, 2010
- Generation of human induced pluripotent stem cell from umbilical cord matrix and amniotic membrane mesenchymal cells, Miguel Angel Esteban, 2010
- The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters, Miguel Angel Esteban, 2010
Awards
- 2011: Friendship Award of Yangcheng
- 2011: Foreign Expert of Chinese Academy of Sciences
- 2012: Foreign Expert of Chinese Academy of Sciences
- 2012: Zhu Li Yuehua Excellent Teacher Award of Chinese Academy of Sciences
- 2012: Excellent Graduate Supervisor of Guangzhou Education Base
- 2015: Distinguished Researcher of Chinese Academy of Sciences
- 2017: Outstanding Scientific Achievement Award of Chinese Academy of Sciences (Outstanding Contributor)
- 2018: Honorary Citizen of Guangzhou
- 2018: Innovation Award of Chinese Society for Stem Cell Research
- 2018: Star of Innovation Talent of Guangzhou Huangpu Development Zone
- 2019: China Government Friendship Award
- 2020: First Prize of Natural Science of Guangdong Province
- 2021: Nanyue Innovation Award of Guangdong Province
