Areas of Focus
- Natural Product Chemistry
- Medicinal Chemistry
Work Experience
- 2014-01~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher
- 2007-07~2013-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
Academic Background & Achievements
- 2004-09--2007-07 PhD: Kunming Institute of Botany, Chinese Academy of Sciences
- 2001-09--2004-07 Master's: Yunnan University
- 1997-09--2001-07 Bachelor's: Yunnan University
Publications
- Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol, Xiao-Zheng Su, Lin-Fei Zhang, Kun Hu, Yang An, Qiao-Peng Zhang, Jian-Wei Tang, Bing-Chao Yan, Xing-Ren Li, Jie Cai, Xiao-Nian Li, Han-Dong Sun, Shi-You Jiang, Pema-Tenzin Puno, 2024
- Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo, Leilei Gou, Grace GarLee Yue, Julia KinMing Lee, Pema Tenzin Puno, Clara BikSan Lau, 2023
- Cyclobutane-containing meroditerpenoids, (+)-isoscopariusins B and C: structure elucidation and biomimetic synthesis, Li, MingXiang, Yan, BingChao, Zhou, Min, Li XingRen, Li, XiaoNian, He, ShiJun, Sun, Handong, Puno, PemaTenzin, 2023
- Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii, Qian Tan, Kun Hu, XiaoNian Li, XingZhi Yang, HanDong Sun, PemaTenzin Puno, 2023
- Phomopsischalins A-C, polycyclic-fused cytochalasins from the endophytic fungus Phomopsis sp. shj2 and their abilities to induce lysosomal function, Rong Chen, Li-Jing Guo, Xue-Dan Li, Xing-Ren Li, Kun Hu, Jian-Wei Tang, Zhen-Nan Ye, Bing-ChaoYan, Pema-Tenzin Puno, 2023
- Four new lanostane triterpenoids featuring extended π-conjugated systems from the stems of Kadsura coccinea, QiQi Zhang, Kun Hu, HanDong Sun, PemaTenzin Puno, 2023
- Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating 4 + 2 cycloaddition and target differentiation of enantiomers, Tao-Bin He, Bing-Chao Yan, Yuan-Fei Zhou, Yue-Qian Sang, Xiao-Nian Li, Han-Dong Sun, Chu Wang, XiaoSong Xue, Pema-Tenzin Puno, 2023
- Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues, Jia-Meng Dai, Bing-Chao Yan, Ling-Mei Kong, Kun Hu, Xing-Ren Li, Xiao-Nian Li, Han-Dong Sun, Yan Li, Pema-Tenzin Puno, 2023
- Scopariusicides D–M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scoparius, XingRen Li, Kun Hu, BingChao Yan, XiaoNian Li, HanDong Sun, Yang Liu, PemaTenzin Puno, 2022
- Discovery and biological evaluation of dispirocyclic and polycyclic ent-clerodane dimers from Isodon scoparius as novel inhibitors of Toll-like receptor signaling, Li, XingRen, Chen, Li, Hu, Kun, Yan, BingChao, Du, Xue, Li, XiaoNian, Sun, HanDong, He, ShiJun, Puno, PemaTenzin, 2022
Awards
- 2014: Special Prize for Schisandra Chemical Research, Provincial Level
- 2013: First Prize for Research on Diterpenoids and Their Anticancer Activity in Isodon Plants, Provincial Level
- 2011: Lu Jiaxi Young Talent Award, Chinese Academy of Sciences
- 2010: First Prize for Excellent Scientific Papers, Yunnan Province
- 2007: Second Prize for Excellent Scientific Papers, Yunnan Province
