Professor | Pema-Tenzin Puno | Asia Growth Partners

Name	Pema-Tenzin Puno
Contact Information	punopematenzin@mail.kib.ac.cn
Language ability	Chinese, English
Province	Yunnan

Name

Pema-Tenzin Puno

Contact Information

punopematenzin@mail.kib.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2004-09--2007-07 PhD: Kunming Institute of Botany, Chinese Academy of Sciences 2001-09--2004-07 Master's: Yunnan University 1997-09--2001-07 Bachelor's: Yunnan University
Work Experience	2014-01~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher 2007-07~2013-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
Awards	2014: Special Prize for Schisandra Chemical Research, Provincial Level 2013: First Prize for Research on Diterpenoids and Their Anticancer Activity in Isodon Plants, Provincial Level 2011: Lu Jiaxi Young Talent Award, Chinese Academy of Sciences 2010: First Prize for Excellent Scientific Papers, Yunnan Province 2007: Second Prize for Excellent Scientific Papers, Yunnan Province

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2004-09--2007-07 PhD: Kunming Institute of Botany, Chinese Academy of Sciences
2001-09--2004-07 Master's: Yunnan University
1997-09--2001-07 Bachelor's: Yunnan University

Work Experience

2014-01~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher
2007-07~2013-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher

Awards

2014: Special Prize for Schisandra Chemical Research, Provincial Level
2013: First Prize for Research on Diterpenoids and Their Anticancer Activity in Isodon Plants, Provincial Level
2011: Lu Jiaxi Young Talent Award, Chinese Academy of Sciences
2010: First Prize for Excellent Scientific Papers, Yunnan Province
2007: Second Prize for Excellent Scientific Papers, Yunnan Province

Areas of Focus	Natural Product Chemistry Medicinal Chemistry
Publications	Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol, Xiao-Zheng Su, Lin-Fei Zhang, Kun Hu, Yang An, Qiao-Peng Zhang, Jian-Wei Tang, Bing-Chao Yan, Xing-Ren Li, Jie Cai, Xiao-Nian Li, Han-Dong Sun, Shi-You Jiang, Pema-Tenzin Puno, 2024 Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo, Leilei Gou, Grace GarLee Yue, Julia KinMing Lee, Pema Tenzin Puno, Clara BikSan Lau, 2023 Cyclobutane-containing meroditerpenoids, (+)-isoscopariusins B and C: structure elucidation and biomimetic synthesis, Li, MingXiang, Yan, BingChao, Zhou, Min, Li XingRen, Li, XiaoNian, He, ShiJun, Sun, Handong, Puno, PemaTenzin, 2023 Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii, Qian Tan, Kun Hu, XiaoNian Li, XingZhi Yang, HanDong Sun, PemaTenzin Puno, 2023 Phomopsischalins A-C, polycyclic-fused cytochalasins from the endophytic fungus Phomopsis sp. shj2 and their abilities to induce lysosomal function, Rong Chen, Li-Jing Guo, Xue-Dan Li, Xing-Ren Li, Kun Hu, Jian-Wei Tang, Zhen-Nan Ye, Bing-ChaoYan, Pema-Tenzin Puno, 2023 Four new lanostane triterpenoids featuring extended π-conjugated systems from the stems of Kadsura coccinea, QiQi Zhang, Kun Hu, HanDong Sun, PemaTenzin Puno, 2023 Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating 4 + 2 cycloaddition and target differentiation of enantiomers, Tao-Bin He, Bing-Chao Yan, Yuan-Fei Zhou, Yue-Qian Sang, Xiao-Nian Li, Han-Dong Sun, Chu Wang, XiaoSong Xue, Pema-Tenzin Puno, 2023 Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues, Jia-Meng Dai, Bing-Chao Yan, Ling-Mei Kong, Kun Hu, Xing-Ren Li, Xiao-Nian Li, Han-Dong Sun, Yan Li, Pema-Tenzin Puno, 2023 Scopariusicides D–M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scoparius, XingRen Li, Kun Hu, BingChao Yan, XiaoNian Li, HanDong Sun, Yang Liu, PemaTenzin Puno, 2022 Discovery and biological evaluation of dispirocyclic and polycyclic ent-clerodane dimers from Isodon scoparius as novel inhibitors of Toll-like receptor signaling, Li, XingRen, Chen, Li, Hu, Kun, Yan, BingChao, Du, Xue, Li, XiaoNian, Sun, HanDong, He, ShiJun, Puno, PemaTenzin, 2022

Areas of Focus

Natural Product Chemistry
Medicinal Chemistry

Publications

Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol, Xiao-Zheng Su, Lin-Fei Zhang, Kun Hu, Yang An, Qiao-Peng Zhang, Jian-Wei Tang, Bing-Chao Yan, Xing-Ren Li, Jie Cai, Xiao-Nian Li, Han-Dong Sun, Shi-You Jiang, Pema-Tenzin Puno, 2024
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo, Leilei Gou, Grace GarLee Yue, Julia KinMing Lee, Pema Tenzin Puno, Clara BikSan Lau, 2023
Cyclobutane-containing meroditerpenoids, (+)-isoscopariusins B and C: structure elucidation and biomimetic synthesis, Li, MingXiang, Yan, BingChao, Zhou, Min, Li XingRen, Li, XiaoNian, He, ShiJun, Sun, Handong, Puno, PemaTenzin, 2023
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii, Qian Tan, Kun Hu, XiaoNian Li, XingZhi Yang, HanDong Sun, PemaTenzin Puno, 2023
Phomopsischalins A-C, polycyclic-fused cytochalasins from the endophytic fungus Phomopsis sp. shj2 and their abilities to induce lysosomal function, Rong Chen, Li-Jing Guo, Xue-Dan Li, Xing-Ren Li, Kun Hu, Jian-Wei Tang, Zhen-Nan Ye, Bing-ChaoYan, Pema-Tenzin Puno, 2023
Four new lanostane triterpenoids featuring extended π-conjugated systems from the stems of Kadsura coccinea, QiQi Zhang, Kun Hu, HanDong Sun, PemaTenzin Puno, 2023
Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating 4 + 2 cycloaddition and target differentiation of enantiomers, Tao-Bin He, Bing-Chao Yan, Yuan-Fei Zhou, Yue-Qian Sang, Xiao-Nian Li, Han-Dong Sun, Chu Wang, XiaoSong Xue, Pema-Tenzin Puno, 2023
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues, Jia-Meng Dai, Bing-Chao Yan, Ling-Mei Kong, Kun Hu, Xing-Ren Li, Xiao-Nian Li, Han-Dong Sun, Yan Li, Pema-Tenzin Puno, 2023
Scopariusicides D–M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scoparius, XingRen Li, Kun Hu, BingChao Yan, XiaoNian Li, HanDong Sun, Yang Liu, PemaTenzin Puno, 2022
Discovery and biological evaluation of dispirocyclic and polycyclic ent-clerodane dimers from Isodon scoparius as novel inhibitors of Toll-like receptor signaling, Li, XingRen, Chen, Li, Hu, Kun, Yan, BingChao, Du, Xue, Li, XiaoNian, Sun, HanDong, He, ShiJun, Puno, PemaTenzin, 2022

Natural Products Chemistry Medicinal Diterpenoids Anticancer Bioactivity Phytochemistry Drug Discovery Synthesis Pharmacology

Chang Min - Wuhan University

Ai-Qin Jiang - Nanjing University

Hongwei Liu - University of Chinese Academy of Sciences

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