Fanglin Sun
Life Science
Tongji University
Shanghai
Language: Chinese, English
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Epigenetics Molecular Mechanisms Regulation Heterochromatin Structure Function Stem Cells Aging Networks Research
Areas of Focus
  • Epigenetics
  • Molecular mechanisms and functions of epigenetic regulation
  • Heterochromatin structure and function
  • Epigenetic regulatory networks in stem cells and aging
Work Experience
  • 1997-2001 Postdoctoral Researcher: Department of Biology, Washington University (St. Louis)
  • 2001-2006 Research Group Leader: Friedrich Miecher Institute (FMI), Switzerland
  • 2006-present Professor, Tsinghua University; various leadership roles at Tongji University
Academic Background & Achievements
  • 1993-1997 PhD: University of Cambridge
  • 2006 Selected for Tsinghua University's 'Hundred Talents Program'
  • 2006 Received funding from the National Natural Science Foundation of China
  • 2007 Appointed as Chang Jiang Scholar Distinguished Professor by the Ministry of Education
  • 2009 Appointed under the 'National Talents Project'
  • 2010 Received a special government allowance recommended by the Ministry of Education
  • 2011 Chief Scientist for the Ministry of Science and Technology's '973' project
  • 2017 Chief Scientist for the Ministry of Science and Technology's major research plan on stem cell aging
Publications
  • Heterochromatin remodeling by CDK12 contributes to learning in Drosophila, Sun FL*, 2015
  • Histone H1-mediated epigenetic regulation controls germline stem cell self-renewal by modulating H4K16 acetylation, Sun FL*, 2015
  • RAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1, Sun FL*, 2015
  • Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation, Sun FL*, 2012
  • Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription, Sun FL*, 2006
  • Sex-specific role of Drosophila HP1 in chromatin and transcription, Sun FL*, 2005
  • HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster, Sun FL*, 2005
  • Long-range nucleosome ordering is associated with gene silencing in Drosophila melanogaster pericentric heterochromatin, Sun FL, 2001
  • The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains, Sun FL, 2000
  • Putting boundaries on silence, Sun FL, 1999
  • Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome, Sun FL, 1997
Awards
  • 2006: National Natural Science Foundation of China funding
  • 2007: Chang Jiang Scholar Distinguished Professor
  • 2009: National Talents Project
  • 2010: Special government allowance
  • 2011: Chief Scientist for '973' project
  • 2017: Chief Scientist for stem cell aging research plan
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