1996-09--2000-06 Bachelor: Shandong Agricultural University
2019-10~Present - Chinese Academy of Sciences, Institute of Microbiology - Project Researcher
2011-08~2012-11 - Cornell University Medical College, USA - Visiting Assistant Professor
2009-06~Present - Chinese Academy of Sciences, Institute of Microbiology - Associate Researcher
2005-07~2009-06 - Chinese Academy of Sciences, Institute of Microbiology - Assistant Researcher
Research
Pathogenesis of Influenza Virus Antiviral Innate Immunity Research on Antiviral and Anti-inflammatory Products
Molecular Therapy, Lei Sun, 2024
PROTAC targeting cyclophilin A controls virus-induced cytokine storm, Heqiao Li, Wenxian Yang, Huizi Li, Xiaoyuan Bai, He Zhang, Wenhui Fan, Wenjun Liu, Lei Sun, 2023
SARS-CoV-2 nonstructural protein 6 triggers endoplasmic reticulum stress-induced autophagy to degrade STING1, Pengtao Jiao, Wenhui Fan, Xiaoya Ma, Runshan Lin, Yuna Zhao, Yabo Li, He Zhang, Xiaojuan Jia, Yuhai Bi, Xiaoli Feng, Minghua Li, Wenjun Liu, Ke Zhang, Lei Sun, 2023
Recombinant porcine interferon cocktail delays the onset and lessens the severity of African swine fever, Pengtao Jiao, Shuchao Wang, Wenhui Fan, He Zhang, Hongyan Yin, Yingli Shang, Hongfei Zhu, Wenjun Liu, Rongliang Hu, Lei Sun, 2023
Delicate regulation of IL-1 beta-mediated inflammation by cyclophilin A, Wenxian Yang, Xiaoyuan Bai, Xiaohan Luan, Jie Min, Xiaodong Tian, Heqiao Li, Huizi Li, Wenqiang Sun, Wei Liu, Wenhui Fan, Wenjun Liu, Lei Sun, 2022
Cyclosporine A Regulates Influenza A Virus-induced Macrophages Polarization and Inflammatory Responses by Targeting Cyclophilin A, Xiaoyuan Bai, Wenxian Yang, Heqiao Li, Yuna Zhao, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun, 2022
Influenza A and B Virus-Triggered Epithelial–Mesenchymal Transition Is Relevant to the Binding Ability of NA to Latent TGF-β, Wenxian Yang, Xiaoyuan Bai, Heqiao Li, Huizi Li, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun, 2022
The Cross-Protective Immunity Landscape Among Different SARS-CoV-2 Variant RBDs, Wenqiang Sun, Lihong He, Huicong Lou, Wenhui Fan, Limin Yang, Gong Cheng, Wenjun Liu, Lei Sun, 2022
Nucleoprotein phosphorylation site (Y385) mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperature, Weinan Zheng, Liang Cui, Minghui Li, Yun Li, Wenhui Fan, Limin Yang, Jing Li, Lei Sun, Wenjun Liu, 2021
Synergistic effect of the responses of different tissues against African swine fever virus, Wenhui Fan, Ying Cao, Pengtao Jiao, Ping Yu, He Zhang, Teng Chen, Xintao Zhou, Yu Qi, Lei Sun, Di Liu, Hongfei Zhu, Wenjun Liu, Rongliang Hu, Jing Li, 2021
The self-assembled nanoparticle-based trimeric RBD mRNA vaccine elicits robust and durable protective immunity against SARS-CoV-2 in mice, Wenqiang Sun, Lihong He, He Zhang, Xiaodong Tian, Zhihua Bai, Lei Sun, Limin Yang, Xiaojuan Jia, Yuhai Bi, Tingrong Luo, Gong Cheng, Wenhui Fan, Wenjun Liu, Jing Li, 2021
Cyclophilin A is a key positive and negative feedback regulator within interleukin-6 trans-signaling pathway, Xiaohan Luan, Wenxian Yang, Xiaoyuan Bai, Heqiao Li, Huizi Li, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun, 2021
Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection, Xiaoyuan Bai, Wenxian Yang, Xiaohan Luan, Huizi Li, Heqiao Li, Deyu Tian, Wenhui Fan, Jing Li, Beinan Wang, Wenjun Liu, Lei Sun, 2021
The effect of cyclophilin A on coronavirus replication and the antiviral effect of its inhibitors, Lu Tian, Wenjun Liu, Lei Sun, 2020
Establishment of RIG-I knockout 293T cell line and its effect on influenza B virus replication, Lu Tian, Pengtao Jiao, Lidan Hou, Yun Li, Zhengyu Song, Wenjun Liu, Wenhui Fan, Lei Sun, 2020
Nucleoprotein phosphorylation site (Y385) mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperature, Lei Sun, 2020
Naproxen Exhibits Broad Anti-influenza Virus Activity in Mice by Impeding Viral Nucleoprotein Nuclear Export, Weinan Zheng, Wenhui Fan, Shuang Zhang, Pengtao Jiao, Yingli Shang, Liang Cui, Madina Mahesutihan, Jing Li, Dayan Wang, George Fu Gao, Lei Sun, Wenjun Liu, 2019
Phosphorylation Status of Tyrosine 78 Residue Regulates the Nuclear Export and Ubiquitination of Influenza A Virus Nucleoprotein, Liang Cui, Weinan Zheng, Minghui Li, Xiaoyuan Bai, Wenxian Yang, Jing Li, Wenhui Fan, George Fu Gao, Lei Sun, Wenjun Liu, 2019
CDC25B promotes influenza A virus replication by regulating the phosphorylation of nucleoprotein, Liang Cui, Madina Mahesutihan, Weinan Zheng, Lijun Meng, Wenhui Fan, Jing Li, Xin Ye, Wenjun Liu, Lei Sun, 2018
The effect of extracellular cyclophilin A on inflammation and the role of its antibody in inhibiting inflammatory response, Wenbo Li, Wei Liu, Can Chen, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun, 2018
Phosphorylation and dephosphorylation of threonine 188 in nucleoprotein is crucial for the replication of influenza A virus, Yun Li, Lei Sun, Weinan Zheng, Madina Mahesutihan, Jing Li, Yuhai Bi, Heran Wang, Wenjun Liu, Ting Rong Luo, 2018
A Promising IFN-Deficient System to Manufacture IFN-Sensitive Influenza Vaccine Virus, Can Chen, Wenhui Fan, Jing Li, Weinan Zheng, Shuang Zhang, Limin Yang, Di Liu, Wenjun Liu, Lei Sun, 2018
CypA Regulates AIP4-Mediated M1 Ubiquitination of Influenza A Virus, Madina Mahesutihan, Weinan Zheng, Liang Cui, Yun Li, Pengtao Jiao, Wenxian Yang, Wei Liu, Jing Li, Wenhui Fan, Limin Yang, Wenjun Liu, Lei Sun, 2018
Differential nucleocytoplasmic shuttling of the nucleoprotein of influenza a viruses and association with host tropism, Jing Li, Weinan Zheng, Lidan Hou, Can Chen, Wenhui Fan, Hongren Qu, Hongren Qu, Jingwen Jiang, Jinhua Liu, George F Gao, Jiyong Zhou, Lei Sun, Wenjun Liu, 2017
Threonine 80 Phosphorylation of Non-Structural Protein NS1 Regulates the Replication of Influenza A Virus by Reducing the Binding Affinity with RIG-I, Wenjun Liu, 2016
Analysis of peptidyl-prolyl cis-trans isomerase activity and genetic variation of vertebrate cyclophilin A, Liqian Ren, Wei Liu, Wenbo Li, Wenjun Liu, Lei Sun, 2016
Novel genetic reassortants in H9N2 influenza A viruses and their diverse pathogenicity to mice, Yuhai Bi, Lu Lu, Jing Li, Yanbo Yin, Yi Zhang, Huijie Gao, Zhuoming Qin, Basit Zeshan, Jinhua Liu, Lei Sun, Wenjun Liu, 2011
