Sheng Wu
Medical School
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English, German
Contact
Chirality Biocatalysis Enzyme Screening Enzyme Characterization 3D Structure Structure-Activity Relationship Catalytic Mechanism Molecular Design Molecular Modification High-Throughput Screening
Areas of Focus
  • Protein Engineering and Biocatalysis
Work Experience
  • 2009-12 to Present - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher, Young Group Leader
  • 2009-10 to 2009-12 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Researcher
  • 2006-09 to 2009-09 - Max-Planck-Institut für Kohlenforschung - Postdoctoral Researcher
Academic Background & Achievements
  • 2001-09 to 2005-12 Ph.D. in Science: Institute of Microbiology, Chinese Academy of Sciences
  • 1998-09 to 2001-07 Master's in Science: Shenyang Pharmaceutical University
  • 1994-09 to 1998-07 Bachelor's in Engineering: Shenyang Pharmaceutical University
Publications
  • Induced allosteric communication in the directed evolution of an enantioselective Baeyer-Villiger monooxygenase, Wu S, Acevedo-Cox JP, Reetz MT, 2010
  • Directed evolution of enantioselective enzymes: an uncreasing catalyst source for organic chemistry, Reetz MT, Wu S, Zheng HB, Prasad S, 2010
  • Laboratory evolution of a robust and enantioselective Baeyer-Villiger monooxygenase for asymmetric catalysis, Reetz MT, Wu S, 2009
  • Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions, Reetz MT, Wu S, 2008
  • Cloning, expression, purification, and characterization of a novel epoxide hydrolase from Aspergillus niger SQ-6, Liu Y, Wu S, Wang JJ, Yang L, Sun WR, 2007
  • Thermostable D-carbamoylase from Sinorhizobium morelens S-5: purification, characterization and gene expression in Escherichia coli, Wu S, Liu Y, Zhao GG, Wang JJ, Sun WR, 2006
  • Enzymatic production of D-p-hydroxyphenylglycine from DL-5-p-hydroxyphenylhydantoin by Sinorhizobium morelens S-5, Wu S, Yang L, Liu Y, Zhao GG, Wang JJ, Sun WR, 2005
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