Yanling Wang
wangyl@ioz.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Medical School
  • 1993-09 to 1998-07 PhD in Science: Institute of Zoology, Chinese Academy of Sciences
  • 1988-09 to 1993-07 Bachelor's in Science: University of Science and Technology of China
  • 2004-10 to Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
  • 2001-05 to 2004-09 - Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
  • 1999-05 to 1999-09 - University of Hong Kong - Visiting Scholar
  • 1998-07 to 2001-04 - Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
  • Zhu Liyuehua Excellent Teacher Award, Institute (School), 2021
  • National Maternal and Child Health Science and Technology Award, Second Prize, National Level, 2017
  • Basic and Clinical Research on Endometriosis, Second Prize, National Level, 2007
  • Advanced Individual in Population and Family Planning Science and Technology Work, Ministry Level, 2006
  • Basic and Clinical Research on Endometriosis, First Prize, Provincial Level, 2005
Placental Development and Pregnancy Maintenance
Pregnancy-Related Diseases such as Preeclampsia and Recurrent Miscarriage
  • Orchestrated feedback regulation between melatonin and sex hormones involving GPER1-PKA-CREB signaling in the placenta., Shao X, Yang Y, Liu Y, Wang Y, Zhao Y, Yu X, Liu J, Li Y, Wang YL, 2023
  • Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at midgestation highlights the defective impacts on foetal health., Du, Lili, Wang, Yanling, Shao, Xuan, Wang, Xiaoyi, Yu, Wenzhe, Bi, Shilei, Chen, Dexiong, Pan, Xingfei, Zeng, Shanshan, Huang, Lijun, Liang, Yingyu, Li, Yulian, Chen, Rufang, Xue, Fengwu, Li, Xiuying, Wang, Shouping, Zhuang, Manli, Liu, Mingxing, Lin, Lin, Yan, Hao, He, Fang, Yu, Lin, Jiang, Qingping, Xiong, Zhongtang, Zhang, Lizi, Cao, Bin, Wang, YanLing, Chen, Dunjin, 2022
  • Decoding the temporal and regional specification of microglia in the developing human brain., Li, Yanxin, Li, Zhongqiu, Yang, Min, Wang, Feiyang, Zhang, Yuehong, Li, Rong, Li, Qian, Gong, Yunxia, Wang, Binhong, Fan, Baoguang, Wang, Chunyue, Chen, Lei, Li, Hong, Ong, Jennie, Teng, Zhaoqian, Jin, Lei, Wang, YanLing, Du, Peng, Jiao, Jianwei, 2022
  • The mystery of the life tree: the placentas., Shao, Xuan, Yu, Wenzhe, Yang, Yun, Wang, Feiyang, Yu, Xin, Wu, Hongyu, Ma, Yeling, Cao, Bin, Wang, YanLing, 2022
  • Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia., Li, Guanlin, Wang, Yongqing, Cao, Guangming, Ma, Yeling, Li, YuXia, Zhao, Yangyu, Shao, Xuan, Wang, YanLing, 2022
  • Placental Development and Pregnancy-Associated Diseases., Xin Yu, Hongyu Wu, Yun Yang, Feiyang Wang, YanLing Wang, Xuan Shao, 2022
  • Single-cell immune landscape of human recurrent miscarriage., Wang F, Jia W, Fan M, Li Z, Liu Y, Ma Y, Shao X, Li YX, Li R, Tu Q, Wang YL, 2021
  • Placenta-Derived MicroRNAs in the Pathophysiology of Human Pregnancy., Xu P, Ma Y, Wu H, Wang YL, 2021
  • Quantitative chemoproteomics reveals O-GlcNAcylation of Cystathionine γ-lyase (CSE) represses trophoblast syncytialization., Liu J, Shao X, Qin W, Yu X, Dang F, Yang Q, Li YX, Chen X, Wang C, Wang YL, 2021
  • MNSFβ regulates placental development by conjugating IGF2BP2 to enhance trophoblast cell invasiveness., Yang Q, Ma Y, Liu Y, Shao X, Jia W, Yu X, Li YX, Yang L, Gu W, Wang H, Wang J, Wang YL, 2021
  • HGF/ c-Met signal regulates early differentiation of placental trophoblast cells., Ma Y, Yu X, Li YX, Wang YL, 2021
  • MNSFbeta Regulates TNFalpha Production by Interacting with RC3H1 in Human Macrophages, and Dysfunction of MNSFbeta in Decidual Macrophages Is Associated With Recurrent Pregnancy Loss., Zhen XX, Yang L, Gu Y, Yang Q, Gu WW, He YP, Wang YL, Wang J, 2021
  • miR-210 regulates placental adaptation to maternal hypoxic stress during pregnancy., Bian X, Liu J, Yang Q, Liu Y, Jia W, Zhang X, Li YX, Shao X, Wang YL, 2021
  • Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supply., Shao X, Cao G, Chen D, Liu J, Yu B, Liu M, Li YX, Cao B, Sadovsky Y, Wang YL, 2021
  • Uterine decidual niche modulates the progressive dedifferentiation of spiral artery vascular smooth muscle cells during human pregnancy., Ma Y, Yu X, Zhang L, Liu J, Shao X, Li YX, Wang YL, 2021
  • Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation., Ma Y, Yang Q, Fan M, Zhang L, Gu Y, Jia W, Li Z, Wang F, Li YX, Wang J, Li R, Shao X, Wang YL, 2020
  • Uterine Scarring Leads to Adverse Pregnant Consequences by Impairing the Endometrium Response to Steroids., Li Z, Bian X, Ma Y, Yang Q, Jia W, Liu J, Wang F, Liu M, Li YX, Shao X, Wang YL, 2020
  • A positive feedback self-regulatory loop between miR-210 and HIF-1α mediated by CPEB2 is involved in trophoblast syncytialization: implication of trophoblast malfunction in preeclampsia., Wang H, Zhao Y, Luo R, Bian X, Wang Y, Shao X, Li YX, Liu M, Wang YL, 2020
  • miR-18a Contributes to Preeclampsia by Downregulating Smad2 (Full Length) and Reducing TGF-β Signaling., Xu P, Li Z, Wang Y, Yu X, Shao X, Li YX, Peng C, Zhao Y, Wang YL, 2020
  • MiR-18a contributes to preeclampsia by downregulating Smad2 (full-length) and reducing transforming growth factor-β signaling., Xu P, Li Z, Wang Y, Yu X, Shao X, Li YX, Peng C, Zhao Y, Wang YL, 2020
  • Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia., Xuan Shao, Yongqing Wang, Yanlei Liu, Xuejiang Guo, Dong Li, Ran Huo, Wentong Jia, Guangming Cao, Yu-Xia Li, Ming Liu, Jiahao Sha, Yangyu Zhao, and Yan-Ling Wang, 2019
  • Low-dose aspirin reduces hypoxia-induced sFlt1 release via the JNK/AP-1 pathway in human trophoblast and endothelial cells., Lin L, Li G, Zhang W, Wang Y, Yang H, 2019
  • A positive feedback self-regulatory loop between miR-210 and HIF-1α mediated by CPEB2 is involved in trophoblast syncytiolization: implication of trophoblast malfunction in preeclampsia Self-regulatory loop for trophoblast malfunction., Hao Wang, Yangyu Zhao, Rongcan Luo, Xiaotao Bian, Yongqing Wang, Xuan Shao, Yu-xia Li, Ming Liu, Yan-Ling Wang, 2019
  • Placental defects are involved in most gene mutations that cause embryonic and fetal death., Shao X, Tan C, Chen D, Wang YL, 2018
  • The intervention effect of aspirin on a lipopolysaccharide-induced preeclampsia-like mouse model by inhibiting the NF-κB pathway., Li G, Ma L, Lin L, Wang YL, Yang H, 2018
  • Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis., Dai J, Liang K, Zhao S, Jia W, Liu Y, Wu H, Lv J, Cao C, Chen T, Zhuang S, Hou X, Zhou S, Zhang X, Chen XW, Huang Y, Xiao RP, Wang YL, Luo T, Xiao J, Wang C, 2018
  • MiR-195 modulates oxidative stress-induced apoptosis and mitochondrial energy production in human trophoblasts via flavin adenine dinucleotide-dependent oxidoreductase domain-containing protein 1 and pyruvate dehydrogenase phosphatase regulatory subunit., Wang H, Zhang L, Guo X, Bai Y, Li YX, Sha J, Peng C, Wang YL, Liu M, 2018
  • Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia., Shao X, Wang Y, Liu Y, Guo X, Li D, Huo R, Jia W, Cao G, Li YX, Liu M, Sha J,
Placental Development Pregnancy Maintenance Trophoblast Cells Uterine Endometrium Embryo Implantation Preeclampsia Recurrent Miscarriage Immune Regulation Molecular Mechanisms Clinical Interventions

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