Professor | Congling Xu | Asia Growth Partners

Name	Congling Xu
Contact Information	Conglingxu@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Congling Xu

Contact Information

Conglingxu@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2018 - PhD in Science: Shanghai Jiao Tong University School of Medicine Received 'Super' Postdoctoral Award from Fudan University
Work Experience	2018 - Fudan University Affiliated Cancer Hospital: Postdoctoral Research 2023 - Tongji University School of Life Sciences and Technology: Distinguished Research Fellow, Dual-appointed Professor at Shanghai Fourth People's Hospital
Awards	Outstanding Award from the Biophysical Society of China Women's Science Forum

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2018 - PhD in Science: Shanghai Jiao Tong University School of Medicine
Received 'Super' Postdoctoral Award from Fudan University

Work Experience

2018 - Fudan University Affiliated Cancer Hospital: Postdoctoral Research
2023 - Tongji University School of Life Sciences and Technology: Distinguished Research Fellow, Dual-appointed Professor at Shanghai Fourth People's Hospital

Awards

Outstanding Award from the Biophysical Society of China Women's Science Forum

Areas of Focus	Transcriptional regulation mechanisms in higher biological developmental processes Transcriptional regulation mechanisms in mammalian early embryonic development Transcriptional regulation mechanisms in mammalian stem cell differentiation and pluripotency maintenance
Publications	R-loop-dependent promoter-proximal termination ensures genome stability, Xu C, Li C, Chen J, Xiong Y, Qiao Z, Fan P, Li C, Ma S, Liu J, Song A, Tao B, Xu T, Xu W, Chi Y, Xue J, Wang P, Ye D, Gu H, Zhang P, Wang Q, Xiao R, Cheng J, Zheng H, Yu X, Zhang Z, Wu J, Liang K, Liu YJ, Lu H, Chen FX, 2023 Stabilization of Integrator/INTAC by the small but versatile DSS1 protein, Xu C, Zhou QX, Zheng H, Song A, Zhao WY, Xiong Y, Huang Z, Xu Y, Cheng J, Chen FX, 2024 From snapshots to a movie: Capturing eukaryotic transcription initiation at single-nucleotide resolution, Shang XY, Xu C, Chen FX, 2024 Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition, Fan P, Shang XY, Song A, Chen S, Mao RY, Chen J, Wang Z, Zheng H, Tao B, Xu W, Jiang W, Yang H, Xu C, Zhang P, Jiang H, Chen FX, 2024 Mechanisms of SOSS-Integrator-PP2A complex in attenuating R-loops and promoting genome stability, Wang J, Xu C, Zhang Z, Chen FX, 2024 SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape, Hu S, Peng L, Xu C, Wang Z, Song A, Chen FX, 2021 Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase, Zheng H, Qi Y, Hu S, Cao X, Xu C, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX, Xu Y, 2020 Synergy between arsenic trioxide and JQ1 on autophagy in pancreatic cancer, Xu C, Wang X, Zhou Y, et al., 2019 Comprehensive epigenetic analyses reveal master regulators driving lung metastasis of breast cancer, Li K, Xu C, Du Y, Junaid M, Kaushik AC, Wei DQ, 2019 KDM3B suppresses APL progression by restricting chromatin accessibility and facilitating the ATRA-mediated degradation of PML/RARα, Wang X, Fan H, Xu C, et al., 2019 Cooperativity of co-factor NR2F2 with Pioneer Factors GATA3, FOXA1 in promoting ERα function, Jiang G, Wang X, Sheng D, Zhou L, Liu Y, Xu C, et al., 2019 Shared genetic and epigenetic mechanisms between chronic periodontitis and oral squamous cell carcinoma, Li S, Liu X, Zhou Y, Acharya A, Savkovic V, Xu C, et al., 2018

Areas of Focus

Transcriptional regulation mechanisms in higher biological developmental processes
Transcriptional regulation mechanisms in mammalian early embryonic development
Transcriptional regulation mechanisms in mammalian stem cell differentiation and pluripotency maintenance

Publications

R-loop-dependent promoter-proximal termination ensures genome stability, Xu C, Li C, Chen J, Xiong Y, Qiao Z, Fan P, Li C, Ma S, Liu J, Song A, Tao B, Xu T, Xu W, Chi Y, Xue J, Wang P, Ye D, Gu H, Zhang P, Wang Q, Xiao R, Cheng J, Zheng H, Yu X, Zhang Z, Wu J, Liang K, Liu YJ, Lu H, Chen FX, 2023
Stabilization of Integrator/INTAC by the small but versatile DSS1 protein, Xu C, Zhou QX, Zheng H, Song A, Zhao WY, Xiong Y, Huang Z, Xu Y, Cheng J, Chen FX, 2024
From snapshots to a movie: Capturing eukaryotic transcription initiation at single-nucleotide resolution, Shang XY, Xu C, Chen FX, 2024
Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition, Fan P, Shang XY, Song A, Chen S, Mao RY, Chen J, Wang Z, Zheng H, Tao B, Xu W, Jiang W, Yang H, Xu C, Zhang P, Jiang H, Chen FX, 2024
Mechanisms of SOSS-Integrator-PP2A complex in attenuating R-loops and promoting genome stability, Wang J, Xu C, Zhang Z, Chen FX, 2024
SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape, Hu S, Peng L, Xu C, Wang Z, Song A, Chen FX, 2021
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase, Zheng H, Qi Y, Hu S, Cao X, Xu C, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX, Xu Y, 2020
Synergy between arsenic trioxide and JQ1 on autophagy in pancreatic cancer, Xu C, Wang X, Zhou Y, et al., 2019
Comprehensive epigenetic analyses reveal master regulators driving lung metastasis of breast cancer, Li K, Xu C, Du Y, Junaid M, Kaushik AC, Wei DQ, 2019
KDM3B suppresses APL progression by restricting chromatin accessibility and facilitating the ATRA-mediated degradation of PML/RARα, Wang X, Fan H, Xu C, et al., 2019
Cooperativity of co-factor NR2F2 with Pioneer Factors GATA3, FOXA1 in promoting ERα function, Jiang G, Wang X, Sheng D, Zhou L, Liu Y, Xu C, et al., 2019
Shared genetic and epigenetic mechanisms between chronic periodontitis and oral squamous cell carcinoma, Li S, Liu X, Zhou Y, Acharya A, Savkovic V, Xu C, et al., 2018

Transcription Regulation Developmental Processes Higher Biology Mammalian Embryonic Stem Cells Pluripotency Differentiation Genomic Stability Transcription Machinery

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