Publications
Programmable A-to-Y base editing by fusing an adenine base editor with an N-methylpurine DNA glycosylase, Tong, Huawei, Wang, Xuchen, Liu, Yuanhua, Liu, Nana, Li, Yun, Luo, Jiamin, Ma, Qian, Wu, Danni, Li, Jiyong, Xu, Chunlong, Yang, Hui, 2023 Mini-dCas13X-mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy, Li, Guoling, Jin, Ming, Li, Zhifang, Xiao, Qingquan, Lin, Jiajia, Yang, Dong, Liu, Yuanhua, Wang, Xing, Xie, Long, Ying, Wenqin, Wang, Haoqiang, Zuo, Erwei, Shi, Linyu, Wang, Ning, Chen, Wanjin, Xu, Chunlong, Yang, Hui, 2023 A high-fidelity RNA-targeting Cas13 restores paternal Ube3a expression and improves motor functions in Angelman syndrome mice, Jinhui Li, Zhixin Shen, Yajing Liu, Zixiang Yan, Yuanhua Liu, Xiang Lin, Junjie Tang, Ruimin Lv, Guannan Geng, ZhiQi Xiong, Changyang Zhou, Hui Yang, 2023 Develop a Compact RNA Base Editor by Fusing ADAR with Engineered EcCas6e, Wang, Xing, Zhang, Renxia, Yang, Dong, Li, Guoling, Fan, Zhanqing, Du, Hongting, Wang, Zikang, Liu, Yuanhua, Lin, Jiajia, Wu, Xiaoqing, Shi, Linyu, Yang, Hui, Zhou, Yingsi, 2023 In vivo treatment of tyrosinaemia with hypercompact Cas12f1, Guo, Ruochen, Li, Zhifang, Li, Guoling, Zhang, Hainan, Zhang, Chang, Huo, Xiaona, Zhang, Xiaoyin, Yang, Xiali, Yang, Rongrong, Liu, Yuanhua, Sun, Xiaozhi, Liu, Xinyu, Yang, Hui, Zhou, Yingsi, Xu, Chunlong, 2023 Treatment of autosomal dominant retinitis pigmentosa caused by RHO-P23H mutation with high-fidelity Cas13X in mice, Zixiang Yan, Yuqin Yao, Luyao Li, Lingqiong Cai, Haiwei Zhang, Shenghai Zhang, Qingquan Xiao, Xing Wang, Erwei Zuo, Chunlong Xu, Jihong Wu, Hui Yang, 2023 RNA base editing therapy cures hearing loss induced by OTOF gene mutation, Yuanyuan Xue, Yong Tao, Xing Wang, Xueling Wang, Yilai Shu, Yuanhua Liu, Wen Kang, Sifan Chen, Zhenzhe Cheng, Boou Yan, Yanwei Xie, Lanting Bi, Haitao Jia, Jinhui Li, Qingquan Xiao, Liying Chen, Xuan Yao, Linyu Shi, Hui Yang, Hao Wu, 2023 Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor, Wei, Yinghui, Zhang, Meiling, Hu, Jing, Zhou, Yingsi, Xue, Mingxing, Yin, Jianhang, Liu, Yuanhua, Feng, Hu, Zhou, Ling, Li, Zhifang, Wang, Dongshuang, Zhang, Zhiguo, Zhou, Yin, Liu, Hongbin, Yao, Ning, Zuo, Erwei, Hu, Jiazhi, Du, Yanzhi, Li, Wen, Xu, Chunlong, Yang, Hui, 2023 Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editing, Xiangfeng Kong, Hainan Zhang, Guoling Li, Zikang Wang, Xuqiang Kong, Lecong Wang, Mingxing Xue, Weihong Zhang, Yao Wang, Jiajia Lin, Jingxing Zhou, Xiaowen Shen, Yinghui Wei, Na Zhong, Weiya Bai, Yuan Yuan, Linyu Shi, Yingsi Zhou, Hui Yang, 2023 Development of miniature base editors using engineered IscB nickase, Han, Dingyi, Xiao, Qingquan, Wang, Yifan, Zhang, Hainan, Dong, Xue, Li, Guoling, Kong, Xiangfeng, Wang, Shihao, Song, Jinhui, Zhang, Weihong, Zhou, Jingxing, Bi, Lanting, Yuan, Yuan, Shi, Linyu, Zhong, Na, Yang, Hui, Zhou, Yingsi, 2023 Programmable deaminase-free base editors for G-to-Y conversion by engineered glycosylase, Tong, Huawei, Liu, Nana, Wei, Yinghui, Zhou, Yingsi, Li, Yun, Wu, Danni, Jin, Ming, Cui, Shuna, Li, Hengbin, Li, Guoling, Zhou, Jingxing, Yuan, Yuan, Zhang, Hainan, Shi, Linyu, Yao, Xuan, Yang, Hui, 2023 Ptbp1 knockdown failed to induce astrocytes to neurons in vivo, Yang, Guixiang, Yan, Zixiang, Wu, Xiaoqing, Zhang, Meng, Xu, Chunlong, Shi, Linyu, Yang, Hui, Fang, Kailun, 2023 An engineered xCas12i with high activity, high specificity, and broad PAM range, Zhang, Hainan, Kong, Xiangfeng, Xue, Mingxing, Hu, Jing, Wang, Zikang, Wei, Yinghui, Wang, Haoqiang, Zhou, Jingxing, Zhang, Weihong, Xu, Mengqiu, Shen, Xiaowen, Yin, Fengcai, Ai, Zhiyuan, Huang, Guangyan, Xia, Junhui, Song, Xueqiong, Li, Hengbin, Yuan, Yuan, Li, Jinhui, Zhong, Na, Zhang, Meiling, Zhou, Yingsi, Yang, Hui, 2023 Develop an efficient and specific AAV-based labeling system for Muller glia in mice, Gao, Yanxia, Fang, Kailun, Yan, Zixiang, Zhang, Haiwei, Geng, Guannan, Wu, Weiwei, Xu, Ding, Zhang, Heng, Zhong, Na, Wang, Qifang, Cai, Minqing, Zuo, Erwei, Yang, Hui, 2022 Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice, Gu, Xi, Hu, Xinde, Wang, Daqi, Xu, Zhijiao, Wang, Fang, Li, Di, Li, Genglin, Yang, Hui, Li, Huawei, Zuo, Erwei, Shu, Yilai, 2022 Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE, Wei, Yinghui, Xu, Chunlong, Feng, Hu, Xu, Kui, Li, Zhifang, Hu, Jing, Zhou, Ling, Wei, Yu, Zuo, Zhenrui, Zuo, Erwei, Li, Wen, Yang, Hui, Zhang, Meiling, 2022 High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects, Tong, Huawei, Huang, Jia, Xiao, Qingquan, He, Bingbing, Dong, Xue, Liu, Yuanhua, Yang, Xiali, Han, Dingyi, Wang, Zikang, Ying, Wenqin, Zhang, Runze, Wei, Yu, Wang, Xuchen, Xu, Chunlong, Zhou, Yingsi, Li, Yanfei, Cai, Minqing, Wang, Qifang, Xue, Mingxing, Li, Guoling, Fang, Kailun, Zhang, Hainan, Yang, Hui, 2022 Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor, Xiao, Qingquan, Xu, Zhijiao, Xue, Yuanyuan, Xu, Chunlong, Han, Lei, Liu, Yuanhua, Wang, Fang, Zhang, Runze, Han, Shuang, Wang, Xing, Li, GengLin, Li, Huawei, Yang, Hui, Shu, Yilai, 2022 Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos, Wei, Yinghui, Li, Zhifang, Xu, Kui, Feng, Hu, Xie, Long, Li, Di, Zuo, Zhenrui, Zhang, Meiling, Xu, Chunlong, Yang, Hui, Zuo, Erwei, 2022 Safeguarding genome integrity during gene-editing therapy in a mouse model of age-related macular degeneration, Yin, Jianhang, Fang, Kailun, Gao, Yanxia, Ou, Liqiong, Yuan, Shaopeng, Xin, Changchang, Wu, Weiwei, Wu, Weiwei, Hong, Jiaxu, Yang, Hui, Hu, Jiazhi, 2022 Gene editing in a Myo6 semi-dominant mouse model rescues auditory function, Xue, Yuanyuan, Hu, Xinde, Wang, Daqi, Li, Di, Li, Yige, Wang, Fang, Huang, Mingqian, Gu, Xi, Xu, Zhijiao, Zhou, Jinan, Wang, Jinghan, Chai, Renjie, Shen, Jun, Chen, ZhengYi, Li, GengLin, Yang, Hui, Li, Huawei, Zuo, Erwei, Shu, Yilai, 2022 Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes, Xu, Chunlong, Zhou, Y
