Areas of Focus
- Asymmetric cell division in stem cells
- Epigenetic mechanisms in stem cell fate determination
Work Experience
- 2012 - Present: Johns Hopkins University, Postdoctoral Research
- 2017 - Present: Tongji University, Researcher and Doctoral Supervisor
Academic Background & Achievements
- 2010 - PhD: Shanghai Institute of Biochemistry and Cell Biology, SIBCB, CAS
- Published in international journals including Cell, Science, and Trends in Cell Biology
- Holder of multiple US technology patents
Publications
- Breaking Symmetry—Asymmetry Histone Inheritance in Stem Cells, Xie, J.*, Wooten, M.*, Tran, V. and Chen, X., 2017
- Histone H3 Threonine 3 Phosphorylation Regulates Asymmetric Histone Inheritance in the in Drosophila Male Germline, Xie J., Wooten M., Tran V., Chen BZ., Pozmanter C., Simbolon C., Betzig E. and Chen X., 2015
- A Novel Function of Acetylcholinesterase: AChE Plays as a DNase that Degrades DNA during Apoptosis, Du AY. *, Xie J. *, Guo KJ., Wan YH., Yang Lei., Niu X., Wu J., Dong XQ., and Zhang XJ., 2015
- Asymmetric Division of Drosophila Male Germline Stem Cell Shows Asymmetric Histone Distribution, Tran V.*, Lim C.*, Xie J. and Chen X., 2012
- Acetylcholinesterase Blocks Cleavage of APP by γ-secretase in 293 Cells and Mouse Brain, Niu X., Zhang XJ., Xie J. and Zhang XJ., 2012
- Induction of a 55 kDa Acetylcholinesterase (AChE) Protein during Apoptosis and its Negative Regulation by the Akt Pathway, Xie J.，Jiang H., Wan YH., Du AY., Guo KJ., Liu T., Ye WY., Niu X., Wu J., Dong XQ., and Zhang XJ., 2011
- AChE Deficiency or Inhibition Decreases Apoptosis and p53 Expression and Protects Renal Function after Ischemia/Reperfusion, Ye WY.*, Gong XW.*, Xie J., Wu J., Zhang XJ., Ouyang Q., Shi YF., and Zhang XJ., 2010
- Acetylcholinesterase in Intestinal Cell Differentiation involves G2/M Cell Cycle Arrest, Xiang AC., Xie J., and Zhang XJ., 2008
- Mitochondria and Calpains Mediate Caspase-Dependent Apoptosis Induced by Doxycycline in HeLa Cells, Wu JC., LiuTJ., Xie J., Xin F., and Guo LH., 2006
