Professor | Hou Yayi | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Hou Yayi
Contact Information	yayihou@nju.edu.cn
Language ability	Chinese, English, Japanese
Province	Jiangsu

Upload Avatar (500 x 500)

Name

Hou Yayi

Contact Information

yayihou@nju.edu.cn

Language ability

Chinese, English, Japanese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Academic Background & Achievements	Bachelor's Degree: Nanjing University Master's Degree: Nanjing University Ph.D.: University of Tokyo Postdoctoral Research: University of Tokyo Visiting Scholar: University of Michigan Medical School Published over 280 papers, with more than 220 indexed by SCI Granted 5 national patents
Awards	National Science and Technology Progress Award Second Prize (2005) Jiangsu Province Science and Technology Progress Award Third Prize (2007) Jiangsu Province Science and Technology Progress Award First Prize (2014) Jiangsu Province Higher Education Science and Technology Research Award Second Prize (2016) Jiangsu Province Science and Technology Progress Award First Prize (2017)

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Academic Background & Achievements

Bachelor's Degree: Nanjing University
Master's Degree: Nanjing University
Ph.D.: University of Tokyo
Postdoctoral Research: University of Tokyo
Visiting Scholar: University of Michigan Medical School
Published over 280 papers, with more than 220 indexed by SCI
Granted 5 national patents

Awards

National Science and Technology Progress Award Second Prize (2005)
Jiangsu Province Science and Technology Progress Award Third Prize (2007)
Jiangsu Province Science and Technology Progress Award First Prize (2014)
Jiangsu Province Higher Education Science and Technology Research Award Second Prize (2016)
Jiangsu Province Science and Technology Progress Award First Prize (2017)

Areas of Focus	Cell and Molecular Immunology
Publications	C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1 + M-MDSCs in relieving lupus-like symptoms, Li D, Lu L, Kong W, Xia X, Pan Y, Li J, Wang J, Wang T, Liang J, Dou H, Hou Y, 2021 IRF-8/miR-451a regulates M-MDSC differentiation via the AMPK/mTOR signal pathway during lupus development, Shi G, Li D, Zhang D, Xu Y, Pan Y, Lu L, Li J, Xia X, Dou H, Hou Y, 2021 Interleukin-34 accelerates intrauterine adhesions progress related to CX3CR1+monocytes/macrophages, Wang J, Li D, Pan Y, Li J, Jiang Q, Liu D, Hou Y, 2021 Placenta-derived IL-32β activates neutrophils to promote preeclampsia development, Liu D, Li Q, Ding H, Zhao G, Wang Z, Cao C, Dai Y, Zheng M, Zhu X, Wu Q, Wang Y, Duan H, Tang H, Lu X, Hou Y, Hu Y, 2021 mTOR inhibitor INK128 promotes wound healing by regulating MDSCs, Li Y, Xu Y, Liu X, Yan X, Lin Y, Tan Q, Hou Y, 2021 Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma, Zhang D, Song Y, Li D, Liu X, Pan Y, Ding L, Shi G, Wang Y, Ni Y, Hou Y, 2021 17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis, Sun Z, Qu J, Xia X, Pan Y, Liu X, Liang H, Dou H, Hou Y, 2021 Urokinase-type plasminogen activator receptor is required for impairing toll-like receptor 7 signaling on macrophage efferocytosis in lupus, Li J, Pan Y, Li D, Xia X, Jiang Q, Dou H, Hou Y, 2020 17β-Estradiol Promotes Trained Immunity in Females Against Sepsis via Regulating Nucleus Translocation of RelB, Sun Z, Pan Y, Qu J, Xu Y, Dou H, Hou Y, 2020 Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells, Li D, Pan Y, Xia X, Liang J, Liu F, Dou H, Hou Y, 2020 Ganoderma lucidum fruiting body extracts inhibit colorectal cancer by inducing apoptosis, autophagy, and G0/G1 phase cell cycle arrest in vitro and in vivo, Liu X, Xu Y, Li Y, Pan Y, Sun Z, Zhao S, Hou Y, 2020 Mesenchymal stem cell transplantation alleviates experimental Sjögren's syndrome through IFN-β/IL-27 signaling axis, Yao G, Qi J, Liang J, Shi B, Chen W, Li W, Tang X, Wang D, Lu L, Chen W, Shi S, Hou Y, Sun L, 2019 SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy, Xu Y, Li Y, Liu X, Pan Y, Sun Z, Xue Y, Wang T, Dou H, Hou Y, 2019 Elevated monocytic-myeloid derived suppressor cells positively correlate with infection frequency in children with RRTIs, Ji J, Ren L, Liu Y, Zheng M, Fang H, Xu Hui, He H, Zhang M, Wang X, Shan J, Hou Y, 2020 MDSCs: friend or foe in systemic lupus erythematosus, Ji J, Li P, Shen C, Dou H, Wang T, Shi L, Hou Y, 2019 Protective effect of dihydroartemisinin in inhibiting senescence of myeloid-derived suppressor cells from lupus mice via Nrf2/HO-1 pathway, Li D, Qi J, Wang J, Pan Y, Li J, Xia X, Dou H, Hou Y, 2019 Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells, Li D, Shi G, Wang J, Zhang D, Pan Y, Dou H, Hou Y, 2019 mTOR inhibitor INK128attenuates systemic lupus erythematosus by regulating inflammation inducedCD11b (+) Gr1(+) cells, Shi G, Li D, Li X, Ren J, Xu J, Ding L, Dou H, Hou Y, 2019 Anti-tumor macrophages activated by ferumoxytolcombined or surface-functionalized with the TLR3agonist poly (I:C) promote melanoma regression, Zhao J, Zhang Z, Xue Y, Wang G, Cheng Y, Pan Y, Zhao S, Hou Y, 2018 GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a, Pan Y, Wang J, Xue Y, Zhao J, Li D, Zhang S, Li K, Hou Y, Fan H, 2018 Carcinoma-associated fibroblasts promote the stemness and chemoresistance ofcolorectal cancer by transferring exosomal lncRNA H19, Ren J, Ding L, Zhang D, Shi G, Xu Q, Shen S, Wang Y, Wang T, Hou Y, 2018 Myeloid-DerivedSuppressor Cells Induce Podocyte Injury Through Increasing Reactive OxygenSpecies in Lupus Nephritis, Zhang D, Xu J, Ren J, Ding L, Shi G, Li D, Dou H, Hou Y, 2018 Anovel stromal lncRNA signature reprograms fibroblasts to promote the growth oforal squamous cell carcinoma via LncRNA-CAF/interleukin-33, Ding L, Ren J, Zhang D, Li Y, Huang X, Hu Q, Wang H, Song Y, Ni Y, Hou Y, 2018 Roles of estrogens on myeloid-derived suppressor cellsin cancer and autoimmune diseases, Ren J, Hou Y, Wang T, 2018 TLR7, a third signal for the robust generation ofspontaneous germinal center B cells in systemic lupus erythematosus, Fan H, Ren D, Hou Y, 2018

Areas of Focus

Cell and Molecular Immunology

Publications

C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1 + M-MDSCs in relieving lupus-like symptoms, Li D, Lu L, Kong W, Xia X, Pan Y, Li J, Wang J, Wang T, Liang J, Dou H, Hou Y, 2021
IRF-8/miR-451a regulates M-MDSC differentiation via the AMPK/mTOR signal pathway during lupus development, Shi G, Li D, Zhang D, Xu Y, Pan Y, Lu L, Li J, Xia X, Dou H, Hou Y, 2021
Interleukin-34 accelerates intrauterine adhesions progress related to CX3CR1+monocytes/macrophages, Wang J, Li D, Pan Y, Li J, Jiang Q, Liu D, Hou Y, 2021
Placenta-derived IL-32β activates neutrophils to promote preeclampsia development, Liu D, Li Q, Ding H, Zhao G, Wang Z, Cao C, Dai Y, Zheng M, Zhu X, Wu Q, Wang Y, Duan H, Tang H, Lu X, Hou Y, Hu Y, 2021
mTOR inhibitor INK128 promotes wound healing by regulating MDSCs, Li Y, Xu Y, Liu X, Yan X, Lin Y, Tan Q, Hou Y, 2021
Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma, Zhang D, Song Y, Li D, Liu X, Pan Y, Ding L, Shi G, Wang Y, Ni Y, Hou Y, 2021
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis, Sun Z, Qu J, Xia X, Pan Y, Liu X, Liang H, Dou H, Hou Y, 2021
Urokinase-type plasminogen activator receptor is required for impairing toll-like receptor 7 signaling on macrophage efferocytosis in lupus, Li J, Pan Y, Li D, Xia X, Jiang Q, Dou H, Hou Y, 2020
17β-Estradiol Promotes Trained Immunity in Females Against Sepsis via Regulating Nucleus Translocation of RelB, Sun Z, Pan Y, Qu J, Xu Y, Dou H, Hou Y, 2020
Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells, Li D, Pan Y, Xia X, Liang J, Liu F, Dou H, Hou Y, 2020
Ganoderma lucidum fruiting body extracts inhibit colorectal cancer by inducing apoptosis, autophagy, and G0/G1 phase cell cycle arrest in vitro and in vivo, Liu X, Xu Y, Li Y, Pan Y, Sun Z, Zhao S, Hou Y, 2020
Mesenchymal stem cell transplantation alleviates experimental Sjögren's syndrome through IFN-β/IL-27 signaling axis, Yao G, Qi J, Liang J, Shi B, Chen W, Li W, Tang X, Wang D, Lu L, Chen W, Shi S, Hou Y, Sun L, 2019
SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy, Xu Y, Li Y, Liu X, Pan Y, Sun Z, Xue Y, Wang T, Dou H, Hou Y, 2019
Elevated monocytic-myeloid derived suppressor cells positively correlate with infection frequency in children with RRTIs, Ji J, Ren L, Liu Y, Zheng M, Fang H, Xu Hui, He H, Zhang M, Wang X, Shan J, Hou Y, 2020
MDSCs: friend or foe in systemic lupus erythematosus, Ji J, Li P, Shen C, Dou H, Wang T, Shi L, Hou Y, 2019
Protective effect of dihydroartemisinin in inhibiting senescence of myeloid-derived suppressor cells from lupus mice via Nrf2/HO-1 pathway, Li D, Qi J, Wang J, Pan Y, Li J, Xia X, Dou H, Hou Y, 2019
Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells, Li D, Shi G, Wang J, Zhang D, Pan Y, Dou H, Hou Y, 2019
mTOR inhibitor INK128attenuates systemic lupus erythematosus by regulating inflammation inducedCD11b (+) Gr1(+) cells, Shi G, Li D, Li X, Ren J, Xu J, Ding L, Dou H, Hou Y, 2019
Anti-tumor macrophages activated by ferumoxytolcombined or surface-functionalized with the TLR3agonist poly (I:C) promote melanoma regression, Zhao J, Zhang Z, Xue Y, Wang G, Cheng Y, Pan Y, Zhao S, Hou Y, 2018
GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a, Pan Y, Wang J, Xue Y, Zhao J, Li D, Zhang S, Li K, Hou Y, Fan H, 2018
Carcinoma-associated fibroblasts promote the stemness and chemoresistance ofcolorectal cancer by transferring exosomal lncRNA H19, Ren J, Ding L, Zhang D, Shi G, Xu Q, Shen S, Wang Y, Wang T, Hou Y, 2018
Myeloid-DerivedSuppressor Cells Induce Podocyte Injury Through Increasing Reactive OxygenSpecies in Lupus Nephritis, Zhang D, Xu J, Ren J, Ding L, Shi G, Li D, Dou H, Hou Y, 2018
Anovel stromal lncRNA signature reprograms fibroblasts to promote the growth oforal squamous cell carcinoma via LncRNA-CAF/interleukin-33, Ding L, Ren J, Zhang D, Li Y, Huang X, Hu Q, Wang H, Song Y, Ni Y, Hou Y, 2018
Roles of estrogens on myeloid-derived suppressor cellsin cancer and autoimmune diseases, Ren J, Hou Y, Wang T, 2018
TLR7, a third signal for the robust generation ofspontaneous germinal center B cells in systemic lupus erythematosus, Fan H, Ren D, Hou Y, 2018

Cell Immunology Molecular Immunology Myeloid Cells Tumor Immunology Autoimmune Diseases Dendritic Cells Mesenchymal Stem Cells Tumor Immune Escape Targeted Therapy Traditional Chinese Medicine

Jianping Zuo - University of Chinese Academy of Sciences

Sun Lingyun - Nanjing University

Huayong Zhang - Nanjing University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us