Professor | Hongyu Wang | Asia Growth Partners

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Name	Hongyu Wang
Contact Information	wanghy@nicemice.cn
Language ability	English, German, Chinese
Province	Jiangsu

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Name

Hongyu Wang

Contact Information

wanghy@nicemice.cn

Language ability

English, German, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Academic Background & Achievements	2006 - PhD: Saarland University, Germany
Work Experience	2006-2010 - University of Dundee, UK - Postdoctoral Researcher 2010-2010 - University of Oxford, UK - Assistant Researcher 2012-2017 - Model Animal Research Institute, Nanjing University - Associate Researcher 2017-present - Model Animal Research Institute, Nanjing University - Associate Professor

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Academic Background & Achievements

2006 - PhD: Saarland University, Germany

Work Experience

2006-2010 - University of Dundee, UK - Postdoctoral Researcher
2010-2010 - University of Oxford, UK - Assistant Researcher
2012-2017 - Model Animal Research Institute, Nanjing University - Associate Researcher
2017-present - Model Animal Research Institute, Nanjing University - Associate Professor

Areas of Focus	Regulation of glucose and lipid metabolism and metabolic syndrome
Publications	Impaired SERCA2a phosphorylation causes diabetic cardiomyopathy through impinging on cardiac contractility and precursor protein processing, Quan C, Zhu SS, Wang RZ, Chen JM, Chen QL, Li M, Su S, Du Q, Liu MJ, Wang HY* and Chen S, 2022 The RalGAPα1−RalA signal module protects cardiac function through regulating calcium homeostasis, Zhu SS, Quan C, Wang RZ, Liang DR, Su S, Rong P, Zhou K, Yang XY, Chen QL, Li M, Du Q, Zhang JZ, Fang L, Wang HY and Chen S, 2022 TRIM24 is an insulin-responsive regulator of P-bodies, Wei W, Chen QL, Liu MJ, Sheng Y, OuYang Q, Feng WK, Yang XY, Ding LF, Su S, Zhang JZ, Fang L, Vidal-Puig A, Wang HY and Chen S, 2022 Tissue-Specific Splicing and Dietary Interaction of a Mutant As160 Allele Determine Muscle Metabolic Fitness in Rodents, Yang XY, Chen QL, Ouyang Q, Rong P, Feng WK, Quan C, Li M, Jiang Q, Liang H, Zhao T-J, Wang H-Y and Chen S, 2021 A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis, Chao Q, Qian D, Min L, Wang R, Ouyang Q, Su S, Zhu S, Chen Q, Sheng Y, Chen L, Wang H, Campbell DG, MacKintosh C, Yang ZZ, Ouyang KF, Wang H-Y & Chen S, 2020 The 14-3-3 protein is an essential component of cyclic AMP signaling for regulation of chemotaxis and development in Dictyostelium, Li M, Quan C, Chen S, Wang H-Y, 2020 Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control, Chen Q, Rong P, Zhu S, Yang X, Ouyang Q, Wang HY, Chen S, 2019 SPEG Controls Calcium Re-Uptake into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain, Quan C, Li M, Du Q, Chen Q, Wang H, Campbell DG, Fang L, Xue B, MacKintosh C, Gao X, Ouyang K, Wang HY, Chen S, 2019 Muscle-specific Rab8a deletion impairs lipid uptake and storage in skeletal muscle and causes hyperlipidemia and hepatosteatosis in mice, Chen Q, Rong P, Xu DJ, Chen L, Xie B, Sheng Y, Li P, Wang HY and Chen S, 2017 The energy sensing LKB1-AMPKα1 pathway regulates IGF1 secretion and consequent activation of the IGF1R-PKB pathway in primary hepatocytes, Chen L, Chen Q, Rong P, Wang HY and Chen S*, 2017

Areas of Focus

Regulation of glucose and lipid metabolism and metabolic syndrome

Publications

Impaired SERCA2a phosphorylation causes diabetic cardiomyopathy through impinging on cardiac contractility and precursor protein processing, Quan C, Zhu SS, Wang RZ, Chen JM, Chen QL, Li M, Su S, Du Q, Liu MJ, Wang HY* and Chen S*, 2022
The RalGAPα1−RalA signal module protects cardiac function through regulating calcium homeostasis, Zhu SS, Quan C, Wang RZ, Liang DR, Su S, Rong P, Zhou K, Yang XY, Chen QL, Li M, Du Q, Zhang JZ, Fang L, Wang HY* and Chen S*, 2022
TRIM24 is an insulin-responsive regulator of P-bodies, Wei W, Chen QL, Liu MJ, Sheng Y, OuYang Q, Feng WK, Yang XY, Ding LF, Su S, Zhang JZ, Fang L, Vidal-Puig A, Wang HY* and Chen S*, 2022
Tissue-Specific Splicing and Dietary Interaction of a Mutant As160 Allele Determine Muscle Metabolic Fitness in Rodents, Yang XY, Chen QL, Ouyang Q, Rong P, Feng WK, Quan C, Li M, Jiang Q, Liang H, Zhao T-J, Wang H-Y and Chen S, 2021
A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis, Chao Q, Qian D, Min L, Wang R, Ouyang Q, Su S, Zhu S, Chen Q, Sheng Y, Chen L, Wang H, Campbell DG, MacKintosh C, Yang ZZ, Ouyang KF, Wang H-Y & Chen S, 2020
The 14-3-3 protein is an essential component of cyclic AMP signaling for regulation of chemotaxis and development in Dictyostelium, Li M, Quan C, Chen S, Wang H-Y, 2020
Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control, Chen Q, Rong P, Zhu S, Yang X, Ouyang Q, Wang HY, Chen S, 2019
SPEG Controls Calcium Re-Uptake into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain, Quan C, Li M, Du Q, Chen Q, Wang H, Campbell DG, Fang L, Xue B, MacKintosh C, Gao X, Ouyang K, Wang HY, Chen S, 2019
Muscle-specific Rab8a deletion impairs lipid uptake and storage in skeletal muscle and causes hyperlipidemia and hepatosteatosis in mice, Chen Q, Rong P, Xu DJ, Chen L, Xie B, Sheng Y, Li P, Wang HY* and Chen S*, 2017
The energy sensing LKB1-AMPKα1 pathway regulates IGF1 secretion and consequent activation of the IGF1R-PKB pathway in primary hepatocytes, Chen L, Chen Q, Rong P, Wang HY* and Chen S*, 2017

Glucose Metabolism Lipid Metabolism Metabolic Syndrome Insulin Signaling Diabetes Cardiomyopathy Calcium Homeostasis Serca2A Ralgap P-Bodies

Shuai Chen - Nanjing University

Hong Lei - Wuhan University

Wen Zhongyuan - Wuhan University

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