Areas of Focus
- Basic and clinical research on nervous system injury and brain glioma
Work Experience
- Current - Nanjing General Hospital - Director of Neurosurgery
- Current - Military Neurosurgery Research Institute - Director
Academic Background & Achievements
- Medical Doctorate
- Published over 200 academic papers, including 80 SCI papers
- Authored 'Neurosurgery Color Atlas'
- Translated 'AL-Mefty Meningiomas'
- Supervised over 60 doctoral and master's students
Publications
- Valproic acid attenuates traumatic brain injury-induced inflammation in vivo: involvement of autophagy and the nrf2/are signaling pathway, Xiangrong Chen, Handong Wang*, Mengliang Zhou, et al., 2018
- Autophagy in traumatic brain injury: a new target for therapeutic intervention, Li Zhang, Handong Wang*, 2018
- SS-31 Provides neuroprotection by reversing mitochondrial dysfunction after traumatic brain injury, Y, Zhu, H. Wang*, J. Fang, et al., 2018
- Targeting Long Noncoding RNA HMMR-AS1 Suppresses and Radiosensitizes Glioblastoma, Junyang Li, Xiangjun Ji, Handong Wang*, 2018
- Neuroprotection by quercetin via mitochondrial function adaptation in traumatic brain injury: PGC-1a pathway as a potential mechanism, Xiang Li, Handong Wang*, Guodao Wen, et al., 2017
- Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways, Zhang L, Wang H*, Fan Y, et al., 2017
- Nrf2-ARE signaling provides neuroprotection in traumatic brain injury via modulation of the ubiquitin proteasome system, Ding H, Wang X, Wang H*, et al., 2017
- Targeting the NF-E2-Related Factor 2 Pathway: a Novel Strategy for Traumatic Brain Injury, Zhang L, Wang H*, 2017
- Interplay between VEGF and Nrf2 regulates angiogenesis due to intracranial venous hypertension, Li L, Pan H, Wang H*, et al., 2016
- Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2–ARE pathway, Jianguo Xu, Handong Wang*, Ke Ding, et al., 2014
- Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism, Ke Ding, Handong Wang*, Jianguo Xu, Tao Li, Li Zhang, Yu Ding, Lin Zhu, Jin He, Mengliang Zhou, 2014
- Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1a, Xiangjun Ji, Handong Wang*, Jianhong Zhu, et al., 2014
Awards
- 2015: Third Prize in Jiangsu Province Science and Technology for research on endogenous neuroprotection targets after central nervous system injury
- 2015: Third Prize in Military Medical Achievements for surgical treatment of secondary hydrocephalus in pineal region tumors
- 2016: Second Prize in Military Science and Technology Progress for research on multiple protective mechanisms of the Nrf2 pathway after central nervous system injury
- 2016: Recognized as 'Outstanding Young and Middle-aged Expert with Outstanding Contributions' in Jiangsu Province
