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Shinan Nie
Medical School
Nanjing University
Jiangsu
Language: Chinese, English
Critical Care
Emergency Medicine
Resuscitation
Toxicology
Infectious Diseases
Acute Care
Trauma
Public Health
Medical Management
Clinical Research
Areas of Focus
- Critical Illness
- Cardiopulmonary Resuscitation
- Poisoning Treatment
- Severe Infection
Work Experience
- Current - Nanjing University Medical School - Chief Physician, Professor, Doctoral Supervisor
- Current - Jinling Hospital - Chief Physician, Department of Emergency Medicine
- Past - Fudan University - EMBA Advanced Training Program
- Past - MD Anderson Cancer Center, University of Texas - Visiting Scholar
Academic Background & Achievements
- PhD: Nanjing University
- EMBA: Fudan University
- Visiting Scholar: MD Anderson Cancer Center, University of Texas
- Published over 80 papers
- Authored, translated, and co-authored 10 books
- Received 1 provincial and ministerial level second prize for scientific and technological progress
- Received 1 national invention patent and 4 utility model patents
Publications
- Clinical Practice Guidelines of the World Society of Emergency Surgery, Shinan Nie, 2020
- Knockdown of circRNA Paralemmin 2 Ameliorates Lipopolysaccharide-induced Murine Lung Epithelial Cell Injury by Sponging miR-330-5p to Reduce ROCK2 Expression, Shinan Nie, 2022
- Interference with connective tissue growth factor attenuated fibroblast-to-myofibroblast transition and pulmonary fibrosis, Shinan Nie, 2022
- Phosphatidylserine-Specific Phospholipase A1 Alleviates Lipopolysaccharide-induced Macrophage Inflammation by Inhibiting MAPKs Activation, Shinan Nie, 2022
- Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion, Shinan Nie, 2022
- Arctigenin attenuates paraquat-induced human lung epithelial A549 cell injury by suppressing ROS/p38 mitogen-activated protein kinases-mediated apoptosis, Shinan Nie, 2022
- Inhibition of Wnt10b/β-catenin signaling alleviates pulmonary fibrogenesis induced by paraquat in vivo and in vitro, Shinan Nie, 2021
- Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway, Shinan Nie, 2021
- MicroRNA-139-5p improves sepsis-induced lung injury by targeting Rho-kinase1, Shinan Nie, 2021
- Xuebijing protects against septic acute liver injury based on regulation of GSK-3β pathway, Shinan Nie, 2021
- Ferulic acid positively modulates the inflammatory response to septic liver injury through the GSK-3β/NF-κB/CREB pathway, Shinan Nie, 2021
- Protective effect of ginsenoside Rg1 on LPS-induced apoptosis of lung epithelial cells, Shinan Nie, 2021
- Pretreatment with intestinal trefoil factor alleviates stress-induced gastric mucosal damage via Akt signaling, Shinan Nie, 2020
- Arctigenin Suppressed Epithelial-Mesenchymal Transition through Wnt3a/β-Catenin Pathway in PQ-Induced Pulmonary Fibrosis, Shinan Nie, 2020
- Paraquat induces pulmonary fibrosis through Wnt/β-catenin signaling pathway and myofibroblast differentiation, Shinan Nie, 2020
- Long non-coding RNA Hsp4 alleviates lipopolysaccharide-induced apoptosis of lung epithelial cells via miRNA-466m-3p/DNAjb6 axis, Shinan Nie, 2020
- Schizandrin B mitigates rifampicin-induced liver injury by inhibiting endoplasmic reticulum stress, Shinan Nie, 2020
- Advances in nanomaterials for use in photothermal and photodynamic therapeutics, Shinan Nie, 2019
- Curcumin relieves paraquat-induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3-mediated inflammatory pathway, Shinan Nie, 2019
- Retrospective study of clinical features and prognosis of edaravone in the treatment of paraquat poisoning, Shinan Nie, 2019
- E3 ubiquitin ligase tripartite motif 7 positively regulates the TLR4-mediated immune response via its E3 ligase domain in macrophages, Shinan Nie, 2019
- Melatonin protects against myocardial ischemia-reperfusion injury by elevating Sirtuin3 expression and manganese superoxide dismutase activity, Shinan Nie, 2018
- Relationship between platelet count, D-dimer, RANTES and NIHSS score in patients with traumatic brain injury and its prognostic value, Shinan Nie, 2022
- Study on the protective effect of naringin on paraquat-induced lung injury in rats, Shinan Nie, 2022
- Diagnostic efficacy of combined free calcium and oxygenation index with rapid sequential organ failure score in identifying adult sepsis, Shinan Nie, 2022
- Septic cardiomyopathy - from pathogenesis to clinical management, Shinan Nie, 2022
- Risk factors for acute liver injury after cardiac arrest resuscitation and its impact on prognosis, Shinan Nie, 2021
- Research progress on clinical treatment and molecular mechanism of paraquat poisoning-induced pulmonary fibrosis, Shinan Nie, 2020
- Study on the correlation between strong ion gap and prognosis in patients with acute paraquat poisoning, Shinan Nie, 2020
- Progress in the treatment of acute aluminum phosphide poisoning, Shinan Nie, 2019
- Research progress on the mechanism of epithelial-mesenchymal transition in paraquat-induced pulmonary fibrosis, Shinan Nie, 2019
- Value of white blood cell count and arterial blood lactate in prognosis evaluation of patients with acute paraquat poisoning, Shinan Nie, 2019
- Clinical study on prone ventilation in the treatment of moderate to severe acute respiratory distress syndrome caused by acute paraquat poisoning, Shinan Nie, 2019
- Role of connective tissue growth factor in paraquat-induced pulmonary fibrosis, Shinan Nie, 2018
- Effect of Xuebijing on Caspase-3 expression in lung tissue and plasma inflammatory factors in paraquat poisoning rats, Shinan Nie, 2018
- Epidemiological analysis of poisoning patients in the emergency rescue room of a large tertiary hospital in Nanjing, Shinan Nie, 2018
- Clinical study on the treatment of acute paraquat poisoning with N-acetylcysteine, Shinan Nie, 2018
- Role of Wnt/β-catenin signaling pathway in paraquat-induced pulmonary fibrosis, Shinan Nie, 2017
Awards
- Provincial and Ministerial Level Second Prize for Scientific and Technological Progress (2017): Research on Risk Factors and Prevention Strategies for Acute Gastric Mucosal Lesions in Critically Ill Patients
- Jiangsu Provincial Health Commission First Prize for New Technology Introduction (2021): Integrated Diagnosis and Treatment Strategy for Acute Paraquat Poisoning
- China Emergency Medicine Career Persistence Award
- First National 'Bethune-style Good Doctor' Honorary Title
- Top Ten Figures of Wuxi Joint Protection Center
- Outstanding Contribution Award for Military Emergency Medicine
- Jiangsu Province Outstanding Young and Middle-aged Expert with Outstanding Contributions
- Second Jiangsu Physician Award
- Second 'Nanjing Good Person (Military System)'
- Sixth 'Top Ten Medical Ethics Models' in Jiangsu Province
